Efficacy and Safety of CDK4/6 Inhibitors: A Focus on HR+/HER2− Early Breast Cancer: CDK4/6 Inhibitors in Early Breast Cancer: E. V. Klocker et al.

Authors: Klocker, Eva Valentina^1,2, Egle, Daniel^2,3, Bartsch, Rupert^2,4, Rinnerthaler, Gabriel^1,2, Gnant, Michael^2,5 michael.gnant@meduniwien.ac.at

Source: Drugs. Feb2025, Vol. 85 Issue 2, p149-169. 21p.

Subject Terms: *PATIENT safety, *BREAST tumors, *EARLY detection of cancer, *PROTEIN-tyrosine kinase inhibitors, *TUMOR markers, *DRUG efficacy, *MEDICAL research, *PROGRESSION-free survival, *PHARMACODYNAMICS

Distribution of spinal damage in patients with axial spondyloarthritis as assessed by MRI: a prospective and blinded study.

Authors: Haidmayer, Andreas, Adelsmayr, Gabriel, Spreizer, Christopher, Klocker, Eva Valentina, Quehenberger, Franz, Fuchsjaeger, Michael, Thiel, Jens, Hermann, Josef

Source: Arthritis Research & Therapy; 1/14/2025, Vol. 27 Issue 1, p1-9, 9p

Longitudinal tumor fraction trajectories predict risk of progression in metastatic HR+ breast cancer patients undergoing CDK4/6 treatment

Authors: Dandachi, Nadia, Posch, Florian, Graf, Ricarda, Suppan, Christoph, Klocker, Eva Valentina, Müller, Hannah Deborah, Lindenmann, Jörg, Terbuch, Angelika, Heitzer, Ellen, Balic, Marija

Source: Molecular oncology. 15(9):2390-2400

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128490295.0x000001&indx=1&recIds=ETOCvdc_100128490295.0x000001

Safety and Clinical Evaluation of Dual Inhibition with Pertuzumab and Trastuzumab Biosimilar SB3 in HER2-Positive Breast Cancer Patients

Authors: Suppan, Christoph, Steiner, Daniel, Klocker, Eva Valentina, Posch, Florian, Henzinger, Elisabeth, Müller, Hannah Deborah, Stöger, Herbert, Dandachi, Nadia, Balic, Marija

Source: Breast care. 16(6):607-613

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136706920.0x000001&indx=1&recIds=ETOCvdc_100136706920.0x000001

External validation of the prognostic relevance of the advanced lung cancer inflammation index (ALI) in pancreatic cancer patients

Authors: Barth, Dominik Andreas, Brenner, Carina, Riedl, Jakob Michael, Prinz, Felix, Klocker, Eva Valentina, Schlick, Konstantin, Kornprat, Peter, Lackner, Karoline, Stöger, Herbert, Stotz, Michael, Gerger, Armin, Pichler, Martin

Source: Cancer medicine. 9(15):5473-5479

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107420009.0x000001&indx=1&recIds=ETOCvdc_100107420009.0x000001

Biomarkers in Her2- Positive Disease

Authors: Klocker, Eva Valentina, Suppan, Christoph

Source: Breast care. 15(6):586-593

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111105983.0x000001&indx=1&recIds=ETOCvdc_100111105983.0x000001

Liquid biopsy in breast cancer.

Authors: Klocker, Eva Valentina, Suppan, Christoph

Source: memo - Magazine of European Medical Oncology; Sep2024, Vol. 17 Issue 3, p194-197, 4p

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression.

Authors: Klocker, Eva Valentina¹ (AUTHOR), Hasenleithner, Samantha² (AUTHOR), Bartsch, Rupert³ (AUTHOR), Gampenrieder, Simon P.⁴ (AUTHOR), Egle, Daniel⁵ (AUTHOR), Singer, Christian F.⁶ (AUTHOR), Rinnerthaler, Gabriel¹ (AUTHOR), Hubalek, Michael⁷ (AUTHOR), Schmitz, Katja^8,9 (AUTHOR), Bago‐Horvath, Zsuzsanna¹⁰ (AUTHOR), Petzer, Andreas¹¹ (AUTHOR), Heibl, Sonja¹² (AUTHOR), Heitzer, Ellen¹³ (AUTHOR), Balic, Marija^1,14 (AUTHOR) marija.balic@medunigraz.at, Gnant, Michael¹⁵ (AUTHOR)

Source: Molecular Oncology. Jun2024, p1. 21p. 6 Illustrations, 4 Charts.

Molecular profiling leading to personalized treatment in breast cancer.

Authors: Klocker, Eva Valentina, Balic, Marija, Steger, Günther

Source: memo - Magazine of European Medical Oncology; Sep2022, Vol. 15 Issue 3, p196-200, 5p

Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.

Authors: Suppan, Christoph, Graf, Ricarda, Jahn, Stephan, Zhou, Qing, Klocker, Eva Valentina, Bartsch, Rupert, Terbuch, Angelika, Kashofer, Karl, Regitnig, Peter, Lindenmann, Joerg, Posch, Florian, Gerritsmann, Hanno, Jost, Philipp J., Heitzer, Ellen, Dandachi, Nadia, Balic, Marija

Source: British Journal of Cancer; Feb2022, Vol. 126 Issue 3, p456-463, 8p

Longitudinal tumor fraction trajectories predict risk of progression in metastatic HR⁺ breast cancer patients undergoing CDK4/6 treatment.

Authors: Dandachi, Nadia, Posch, Florian, Graf, Ricarda, Suppan, Christoph, Klocker, Eva Valentina, Müller, Hannah Deborah, Lindenmann, Jörg, Terbuch, Angelika, Heitzer, Ellen, Balic, Marija

Source: Molecular Oncology; Sep2021, Vol. 15 Issue 9, p2390-2400, 11p

Decreased Activity of Circulating Butyrylcholinesterase in Blood Is an Independent Prognostic Marker in Pancreatic Cancer Patients.

Authors: Klocker, Eva Valentina¹ (AUTHOR) eva.klocker@medunigraz.at, Barth, Dominik Andreas^1,2,3 (AUTHOR) dominik.barth@medunigraz.at, Riedl, Jakob Michael¹ (AUTHOR) j.riedl@medunigraz.at, Prinz, Felix¹ (AUTHOR) felix.prinz@medunigraz.at, Szkandera, Joanna¹ (AUTHOR) joanna.szkandera@medunigraz.at, Schlick, Konstantin⁴ (AUTHOR) k.schlick@salk.at, Kornprat, Peter⁵ (AUTHOR) peter.kornprat@medunigraz.at, Lackner, Karoline⁶ (AUTHOR) karoline.lackner@medunigraz.at, Lindenmann, Jörg⁷ (AUTHOR) jo.lindenmann@medunigraz.at, Stöger, Herbert¹ (AUTHOR) herbert.stoeger@medunigraz.at, Stotz, Michael¹ (AUTHOR) michael.stotz@medunigraz.at, Gerger, Armin¹ (AUTHOR) armin.gerger@medunigraz.at, Pichler, Martin^1,2,3 (AUTHOR) martin.pichler@medunigraz.at

Source: Cancers. May2020, Vol. 12 Issue 5, p1154. 1p.

Subject Terms: *CHOLINESTERASES, *CONFIDENCE intervals, *MULTIVARIATE analysis, *PANCREATIC tumors, *STATISTICS, *TUMOR markers, *PROPORTIONAL hazards models, *DESCRIPTIVE statistics, *KAPLAN-Meier estimator

Patterns of Recurrence after Neoadjuvant Therapy in Early Breast Cancer, according to the Residual Cancer Burden Index and Reductions in Neoadjuvant Treatment Intensity.

Authors: Suppan, Christoph, Posch, Florian, Mueller, Hannah Deborah, Mischitz, Nina, Steiner, Daniel, Klocker, Eva Valentina, Setaffy, Lisa, Bargfrieder, Ute, Hammer, Robert, Hauser, Hubert, Jost, Philipp J., Dandachi, Nadia, Lax, Sigurd, Balic, Marija, Wong, David

Source: Cancers; 5/15/2021, Vol. 13 Issue 10, p2492-2492, 1p

Subject Terms: BREAST cancer prognosis, SURVIVAL, ANTHRACYCLINES, TERPENES, CONFIDENCE intervals, CANCER chemotherapy, CANCER relapse, TREATMENT effectiveness, DESCRIPTIVE statistics, COMBINED modality therapy, BREAST tumors