SPR is a fast and straightforward method to estimate the binding constants of cyclic dinucleotides to their binding partners, such as STING or poxin

Authors: Sülzen, Hagen, Klima, Martin, Duchoslav, Vojtech, Boura, Evzen ^⁎

Source: In Biophysical Chemistry April 2025 319

Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase

Authors: Krejčová, Kateřina, Krafcikova, Petra, Klima, Martin, Chalupska, Dominika, Chalupsky, Karel, Zilecka, Eva, Boura, Evzen

Source: In Structure 8 August 2024 32(8):1099-1109

Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function

Authors: Klima, Martin, Dejmek, Milan, Duchoslav, Vojtech, Eisenreichova, Andrea, Sala, Michal, Chalupsky, Karel, Chalupska, Dominika, Novotná, Barbora, Birkuš, Gabriel, Nencka, Radim, Boura, Evzen

Source: In Structure 4 April 2024 32(4):433-439

Does the Sign of Charge Affect the Surface Affinity of Simple Ions?

Authors: Hantal, György, Klíma, Martin, McFegan, Louisa, Kolafa, Jiří, Jedlovszky, Pál

Source: Journal of physical chemistry.B. 127(27):6205-6216

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633097950&indx=1&recIds=ETOCRN633097950

Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy

Authors: Dejmek, Milan, Brazdova, Andrea, Otava, Tomáš, Polidarova, Marketa Pimkova, Klíma, Martin, Smola, Miroslav, Vavrina, Zdenek, Buděšínský, Miloš, Dračínský, Martin, Liboska, Radek, Boura, Evzen, Birkuš, Gabriel, Nencka, Radim

Source: In European Journal of Medicinal Chemistry 5 November 2023 259

SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses

Authors: Li, Fengling ^{a, 1}, Ghiabi, Pegah ^{a, 1}, Hajian, Taraneh ^{a, b}, Klima, Martin ^c, Li, Alice Shi Ming ^{b, d}, Khalili Yazdi, Aliakbar ^a, Chau, Irene ^a, Loppnau, Peter ^a, Kutera, Maria ^a, Seitova, Almagul ^a, Bolotokova, Albina ^a, Hutchinson, Ashley ^a, Perveen, Sumera ^a, Boura, Evzen ^c, Vedadi, Masoud ^{a, b, d, e, ⁎}

Source: In BBA - General Subjects April 2023 1867(4)

The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors

Authors: Kolcheva, Marharyta, Ladislav, Marek, Netolicky, Jakub, Kortus, Stepan, Rehakova, Kristyna, Krausova, Barbora Hrcka, Hemelikova, Katarina, Misiachna, Anna, Kadkova, Anna, Klima, Martin, Chalupska, Dominika, Horak, Martin

Source: In Neuropharmacology 1 January 2023 222

Asynchronní nádorová kvadruplicita(triplicita urologických malignit)
Asynchronous primary tumour quadruplicity (triplicity of urological malignancies)

Authors: Klíma, Martin, Schraml, Jan, Broul, Marek, Hlavička, Martin, Skála, Petr, Čegan, Martin, Chodacká, Martina

Contributors: Klíma, Martin, Schraml, Jan , 1968-, Broul, Marek, Hlavička, Martin, Skála, Petr, Čegan, Martin, Chodacká, Martina

Source: Česká urologie : Czech urology : moderní časopis pro klinické a praktické urology | 2015 Volume:19 | Number:3

Availability: http://data.europeana.eu/aggregation/europeana/336/uuid_bmc16034676_3b42c8ae_f5b3_47b0_a0e8_c17364842c69

The mycobacterial guaB1 gene encodes a guanosine 5′‐monophosphate reductase with a cystathionine‐β‐synthase domain

Authors: Knejzlík, Zdeněk, Doležal, Michal, Herkommerová, Klára, Clarova, Kamila, Klíma, Martin, Dedola, Matteo, Zborníková, Eva, Rejman, Dominik, Pichová, Iva

Source: FEBS journal. 289(18):5571-5598

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161222136.0x000001&indx=1&recIds=ETOCvdc_100161222136.0x000001

Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential

Authors: Dejmek, Milan, Šála, Michal, Brazdova, Andrea, Vanekova, Lenka, Smola, Miroslav, Klíma, Martin, Břehová, Petra, Buděšínský, Miloš, Dračínský, Martin, Procházková, Eliška, Zavřel, Martin, Šimák, Ondřej, Páv, Ondřej, Boura, Evzen, Birkuš, Gabriel, Nencka, Radim

Source: In Structure 4 August 2022 30(8):1146-1156

Molecular dynamics of evaporative cooling of water clusters.

Authors: Klíma, Martin, Janek, Jiří, Kolafa, Jiří

Source: Physical Chemistry Chemical Physics (PCCP); 2/14/2025, Vol. 27 Issue 6, p2939-2947, 9p

Properties of water and argon clusters developed in supersonic expansions.

Authors: Klíma, Martin¹ (AUTHOR), Celný, David¹ (AUTHOR), Janek, Jiří¹ (AUTHOR), Kolafa, Jiří¹ (AUTHOR) jiri.kolafa@vscht.cz

Source: Journal of Chemical Physics. 9/28/2023, Vol. 159 Issue 12, p1-12. 12p.

Subject Terms: *WATER clusters, *EVAPORATIVE cooling, *FLUID dynamics, *MOLECULAR dynamics, *HYDRAULIC couplings, *MOLECULAR beams, *WATER vapor

Molecular Dynamics of Heterogeneous Systems on GPUs and Their Application to Nucleation in Gas Expanding to a Vacuum

Authors: Celný, David, Klíma, Martin, Kolafa, Jiří

Source: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 17(12):7397-7405

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632733062&indx=1&recIds=ETOCRN632733062

Structural analysis of the putative SARS-CoV-2 primase complex

Authors: Konkolova, Eva, Klima, Martin, Nencka, Radim, Boura, Evzen

Source: In Journal of Structural Biology 1 August 2020 211(2)

Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation

Authors: Dubankova, Anna, Horova, Vladimira, Klima, Martin, Boura, Evzen

Source: In Journal of Structural Biology 1 November 2019 208(2):92-98

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

Authors: Zilecka, Eva, Klima, Martin, Stefek, Milan, Dejmek, Milan, Nencka, Radim, Boura, Evzen

Source: In Journal of Structural Biology: X December 2024 10

Structural analysis of phosphatidylinositol 4-kinase IIIβ (PI4KB) – 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro

Authors: Chalupska, Dominika, Eisenreichova, Andrea, Różycki, Bartosz, Rezabkova, Lenka, Humpolickova, Jana, Klima, Martin, Boura, Evzen

Source: In Journal of Structural Biology October 2017 200(1):36-44

Kobuviral Non-structural 3A Proteins Act as Molecular Harnesses to Hijack the Host ACBD3 Protein

Authors: Klima, Martin, Chalupska, Dominika, Różycki, Bartosz, Humpolickova, Jana, Rezabkova, Lenka, Silhan, Jan, Baumlova, Adriana, Dubankova, Anna, Boura, Evzen

Source: In Structure 7 February 2017 25(2):219-230

Direct Molecular Dynamics Simulation of Nucleation during Supersonic Expansion of Gas to a Vacuum

Authors: Klíma, Martin, Kolafa, Jiří

Source: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 14(5):2332-2340

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632714344&indx=1&recIds=ETOCRN632714344

Agent-Based Production Scheduling for Aircraft Manufacturing Ramp-up
Industrial applications of holonic and multi-agent systems

Authors: Vrba, Pavel, Harcuba, Ondřej, Klíma, Martin, Mařík, Vladimír

Source: Lecture notes in computer science. 9266:145-156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN600641620&indx=1&recIds=ETOCCN600641620