Dramatic response to alectinib in an ALK‐positive LCNEC patient with a poor performance status: A case report

Authors: Kazuki Masuda, Masafumi Saiki, So Shimamura, Shuichiro Ide, Yoshinori Uchida, Yusuke Sogami, Hiroshi Ishihara, Fumi Ikeda, Kiyotaka Kugiyama

Source: Respirology Case Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)

Subject Terms: alectinib, echinoderm microtubule‐associated protein‐like 4‐anaplastic lymphoma kinase, large cell neuroendocrine carcinoma, poor performance status, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/2051-3380

Access URL: https://doaj.org/article/f274a77b6ad3431cb71acad07bf6058f

Structural Thickening of Medial Layer in Coronary Artery With Spasm in Patients With Myocardial Infarction

Authors: Takamitsu Nakamura, Takeo Horikoshi, Kiyotaka Kugiyama

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 2 (2021)

Subject Terms: coronary atherosclerosis, coronary spasm, coronary vasomotion, optical coherence tomography, smooth muscle, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/39256dc9279b4381a35f4c0de1255970

A case of drug induced lung injury caused by levofloxacin eye drops

Authors: Naoki Hosogaya, Kazuhiro Toida, Hiroshi Ishihara, Kiyotaka Kugiyama

Source: Respiratory Medicine Case Reports, Vol 24, Iss , Pp 12-15 (2018)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213007118300509; https://doaj.org/toc/2213-0071

Access URL: https://doaj.org/article/ba83d6d65635418f9745ddea90ea506f

A Propensity Score Matched Analysis of Statin Effects on Major Adverse Cardiac Events after Percutaneous Coronary Intervention in Patients Over 75 Years Old.

Authors: Takeo Horikoshi, Takamitsu Nakamura, Toru Yoshizaki, Jun Nakamura, Yosuke Watanabe, Manabu Uematsu, Aritaka Makino, Yukio Saito, Jun-ei Obata, Takao Sawanobori, Hajime Takano, Ken Umetani, Akinori Watanabe, Tetsuya Asakawa, Akira Sato, Kiyotaka Kugiyama

Source: Internal Medicine; 2022, Vol. 61 Issue 18, p2711-2719, 9p

Relationship of a thinned medial layer to the attenuated contractile response in atherosclerotic coronary arteries.

Authors: Takamitsu Nakamura, Takeo Horikoshi, Kiyotaka Kugiyama

Source: American Journal of Physiology: Heart & Circulatory Physiology; Jan2020, Vol. 318 Issue 1, pH135-H142, 8p

Subject Terms: OPTICAL coherence tomography, SMOOTH muscle, CORONARY arteries, MYOCARDIAL infarction, IMAGE analysis

Human soluble phospholipase A2 receptor is an inhibitor of the integrin-mediated cell migratory response to collagen-I.

Authors: Kazunori Watanabe, Kazuhiro Watanabe, Yosuke Watanabe, Daisuke Fujioka, Takamitsu Nakamura, Kazuto Nakamura, Jun-ei Obata, Kiyotaka Kugiyama

Source: American Journal of Physiology: Cell Physiology; Sep2018, Vol. 315 Issue 3, pC398-C408, 11p

Sustained myocardial production of stromal cell-derived factor-1α was associated with left ventricular adverse remodeling in patients with myocardial infarction.

Authors: Manabu Uematsu, Toru Yoshizaki, Takuya Shimizu, Jun-ei Obata, Takamitsu Nakamura, Daisuke Fujioka, Kazuhiro Watanabe, Yosuke Watanabe, Kiyotaka Kugiyama

Source: American Journal of Physiology: Heart & Circulatory Physiology; Nov2015, Vol. 309 Issue 10, pH1764-H1771, 8p

Subject Terms: MYOCARDIAL infarction, STROMAL cells, VENTRICULAR remodeling, CONNECTIVE tissue cells, MYOCARDIAL revascularization

Twelve weeks of smoking cessation therapy with varenicline increases the serum levels of apolipoprotein A-I only in the success group.

Authors: Masahiko Iwaoka, Hiromasa Shimamura, Takeshi Tsuji, Kiyotaka Kugiyama

Source: Journal of Cardiology; Sept/Oct2014, Vol. 64 Issue 3/4, p318-323, 6p

The combined assessment of flow-mediated dilation of the brachial artery and brachial-ankle pulse wave velocity improves the prediction of future coronary events in patients with chronic coronary artery disease.

Authors: Wataru Sugamata, Takamitsu Nakamura, Manabu Uematsu, Yoshinobu Kitta, Daisuke Fujioka, Yukio Saito, Ken-ichi Kawabata, Jun-ei Obata, Yosuke Watanabe, Kazuhiro Watanabe, Kiyotaka Kugiyama

Source: Journal of Cardiology; Sept/Oct2014, Vol. 64 Issue 3/4, p179-184, 6p

Insulin resistance negatively affects long-term outcome in non-diabetic patients with coronary artery disease after therapies to reduce atherosclerotic risk factors.

Authors: Yoshinobu Kitta, Takamitsu Nakamura, Manabu Uematsu, Wataru Sugamata, Juntarou Deyama, Daisuke Fujioka, Yukio Saito, Kenichi Kawabata, Jun-ei Obata, Kiyotaka Kugiyama

Source: Journal of Cardiology; NovDec2013, Vol. 62 Issue 5-6, p348-353, 6p

Deficiency of Phospholipase A2 Receptor Exacerbates Ovalbumin-Induced Lung Inflammation.

Authors: Shun Tamaru, Hideto Mishina, Yosuke Watanabe, Kazuhiro Watanabe, Daisuke Fujioka, Soichiro Takahashi, Koji Suzuki, Takamitsu Nakamura, Jun-ei Obata, Kenichi Kawabata, Yasunori Yokota, Makoto Murakami, Kohji Hanasaki, Kiyotaka Kugiyama

Source: Journal of Immunology; 8/1/2013, Vol. 191 Issue 3, p1021-1028, 8p

Disruption of group IVA cytosolic phospholipase A2 attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway.

Authors: Yukio Saito, Kazuhiro Watanabe, Daisuke Fujioka, Takamitsu Nakamura, Jun-ei Obata, Kenichi Kawabata, Yosuke Watanabe, Hideto Mishina, Shun Tamaru, Yoshihiro Kita, Takao Shimizu, Kiyotaka Kugiyama

Source: American Journal of Physiology: Heart & Circulatory Physiology; May2012 Part2, Vol. 302 Issue 10, pH2018-H2030, 13p

Group X secretory PLA2 in neutrophils plays a pathogenic role in abdominal aortic aneurysms in mice.

Authors: Kazuhiro Watanabe, Daisuke Fujioka, Yukio Saito, Takamitsu Nakamura, Jun-ei Obata, Kenichi Kawabata, Yosuke Watanabe, Hideto Mishina, Shun Tamaru, Kohji Hanasaki, Kiyotaka Kugiyama

Source: American Journal of Physiology: Heart & Circulatory Physiology; Jan2012, Vol. 302 Issue 1, pH95-H104, 10p

A synthetic small molecule, ONO-1301, enhances endogenous growth factor expression and augments angiogenesis in the ischaemic heart.

Authors: Kazuto Nakamura, Masataka Sata, Hiroshi Iwata, Yoshiki Sakai, Yasunobu Hirata, Kiyotaka Kugiyama, Ryozo Nagai

Source: Clinical Science; 2007, Vol. 112 Issue 12, p607-616, 10p

Subject Terms: PROSTACYCLIN, NEOVASCULARIZATION, ISCHEMIA, FIBROBLASTS

Angiogenic strategy for human ischemic heart disease: Brief overview.

Authors: Shoji Fukuda, Shinpei Yoshii, Shigeaki Kaga, Masahiko Matsumoto, Kiyotaka Kugiyama, Nilanjana Maulik

Source: Molecular & Cellular Biochemistry; Sep2004, Vol. 264 Issue 1/2, p143-149, 7p

Increased Autoanitbodies Against Oxidized Low-Density Lipoprotein in Coronary Circulation in Patients with Coronary Spastic Angina.

Authors: Hisao Ogawa, Hirofumi Soejima, Keiji Takazoe, Shinzo Miyamoto, Kajiwara, Ichiro, Hideki Shimomura, Tomohiro Sakamoto, Michihiro Yoshimura, Kiyotaka Kugiyama, Masahiro Kimura, Hirofumi Yasue

Source: Angiology; Mar2001, Vol. 52 Issue 3, p167, 8p, 1 Chart, 3 Graphs

Subject Terms: AUTOANTIBODIES, ANGINA pectoris, LOW density lipoproteins, CORONARY circulation

Cigarette smoke extract contracts isolated porcine coronary arteries by superoxide anion-mediated degradation of EDRF.

Authors: TOYOAKI MUROHARA, KIYOTAKA KUGIYAMA, MASAMICHI OHGUSHI, SEIGO SUGIYAMA, HIROFUMI YASUE

Source: American Journal of Physiology: Heart & Circulatory Physiology; 1994, Vol. 266 Issue 3, pH874-H880, 7p

Abstract 11297: S-Glutathionylation, One of the Oxidative Protein Modifications, Stimulates Adipogenesis and Obesity by Stabilizing C/EBP Beta Through Inhibition of SUMO E3 Ligase PIAS1 Interaction.

Authors: Watanabe, Yosuke, Watanabe, Kazuhiro, Fujioka, Daisuke, Nakamura, Kazuto, Kawabata, Kenichi, Kishi, Hiroki, Fujihara, Yuki, Matsui, Reiko, Bachschmid, Markus M, Cohen, Richard A, Kiyotaka, Kugiyama

Source: Circulation; 2018 Supplement, Vol. 138, pA11297-A11297, 1p

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Group V secreted phospholipase A2 plays a protective role against aortic dissection.

Authors: Kazuhiro Watanabe^1,2, Yoshitaka Taketomi^2,3, Yoshimi Miki^2,3, Kiyotaka Kugiyama^1,4, Makoto Murakami^2,3,4,5

Source: Journal of Biological Chemistry. 7/24/2020, Vol. 295 Issue 30, p10092-10111. 20p.

Subject Terms: *AORTIC dissection, *PHOSPHOLIPASE A2, *LINOLEIC acid, *PHOSPHOLIPASES, *UNSATURATED fatty acids, *LYSYL oxidase