Bempegaldesleukin (BEMPEG; NKTR‐214) efficacy as a single agent and in combination with checkpoint‐inhibitor therapy in mouse models of osteosarcoma

Authors: Hennessy, Marlene, Wahba, Andrew, Felix, Kumar, Cabrera, Mariella, Segura, Maria Gabriela, Kundra, Vikas, Ravoori, Murali K., Stewart, John, Kleinerman, Eugenie S., Jensen, Vanessa Behrana, Gopalakrishnan, Vidya, Pena, Rhoneil, Quach, Phi, Kim, Grace, Kivimäe, Saul, Madakamutil, Loui, Overwijk, Willem W., Zalevsky, Jonathan, Gordon, Nancy

Source: International journal of cancer. 148(8):1928-1937

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115429349.0x000001&indx=1&recIds=ETOCvdc_100115429349.0x000001

Clodronate Improves Survival of Transplanted Hoxb8 Myeloid Progenitors with Constitutively Active GMCSFR in Immunocompetent Mice

Authors: Lee, Simon, Kivimäe, Saul, Szoka, Francis C.

Source: In Molecular Therapy - Methods & Clinical Development 15 December 2017 7:60-73

Macrophage-based cell therapies: The long and winding road

Authors: Lee, Simon, Kivimäe, Saul, Dolor, Aaron, Szoka, Francis C.

Source: In Journal of Controlled Release 28 October 2016 240:527-540

Improving the distribution of Doxil® in the tumor matrix by depletion of tumor hyaluronan

Authors: Kohli, Aditya G., Kivimäe, Saul, Tiffany, Matthew R., Szoka, Francis C.

Source: In Journal of Controlled Release 10 October 2014 191:105-114

Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock

Authors: Kaasik, Krista, Kivimäe, Saul, Allen, Jasmina J., Chalkley, Robert J., Huang, Yong, Baer, Kristin, Kissel, Holger, Burlingame, Alma L., Shokat, Kevan M., Ptáček, Louis J., Fu, Ying-Hui

Source: In Cell Metabolism 5 February 2013 17(2):291-302

Delivery of Lipid Micelles into Infarcted Myocardium Using a Lipid-Linked Matrix Metalloproteinase Targeting Peptide

Authors: Nguyen, Juliane, Sievers, Richard, Motion, J. P. Michael, Kivimäe, Saul, Fang, Qizhi, Lee, Randall J.

Source: Molecular pharmaceutics. 12(4):1150-1157

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600644920&indx=1&recIds=ETOCRN600644920

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in Colorectal Cancer and Is a Therapeutic Target of Histone Modifications

Authors: Jiang, Xia, Tan, Jing, Li, Jingsong, Kivimäe, Saul, Yang, Xiaojing, Zhuang, Li, Lee, Puay Leng, Chan, Mark T.W., Stanton, Lawrence W., Liu, Edison T., Cheyette, Benjamin N.R., Yu, Qiang

Source: In Cancer Cell 2008 13(6):529-541

Fusion of a Short Peptide that Binds Immunoglobulin G to a Recombinant Protein Substantially Increases Its Plasma Half-Life in Mice.

Authors: Sockolosky, Jonathan T.^1,2, Kivimäe, Saul², Szoka, Francis C.^1,2 szoka@cgl.ucsf.edu

Source: PLoS ONE. Jul2014, Vol. 9 Issue 7, p1-10. 10p.

Subject Terms: *PEPTIDES, *IMMUNOGLOBULIN G, *RECOMBINANT proteins, *BLOOD plasma, *FLUORESCENT proteins, *LABORATORY mice

Replication of a chimeric origin containing elements from Epstein–Barr virus ori P and bovine papillomavirus minimal origin

Authors: Kivimäe, Saul, Allikas, Aire, Kurg, Reet, Ustav, Mart ^*

Source: In Virus Research 2001 75(1):1-11

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak.

Authors: Suriben, Rowena¹, Kivimäe, Saul², Fisher, Daniel A. C.², Moon, Randall T.³, Cheyette, Benjamin N. R.⁴

Source: Nature Genetics. Sep2009, Vol. 41 Issue 9, p977-985. 9p. 3 Diagrams, 3 Graphs.

Subject Terms: *GENETIC mutation, *LABORATORY mice, *GENITOURINARY organs, *ALIMENTARY canal, *MORPHOGENESIS

Activating PER Repressor through a DBT-Directed Phosphorylation Switch.

Authors: Kivimäe, Saul¹, Saez, Lino¹, Young, Michael W.¹ young@mail.rockefeller.edu

Source: PLoS Biology. Jul2008, Vol. 6 Issue 7, pe183. 14p. 4 Black and White Photographs, 2 Diagrams, 2 Charts, 2 Graphs.

Subject Terms: *CHEMICAL reactions, *PHOSPHORYLATION, *BIOLOGICAL rhythms, *CIRCADIAN rhythms, *DROSOPHILA, *PROTEIN kinases

NKTR-255, a Polymer-Conjugated IL-15 Enhances Antibody-Dependent Cellular Cytotoxicity Mediated By NK Cells in a B Cell Lymphoma Model

Authors: Miyazaki, Takahiro ^*, Kivimäe, Saul ^*, Hennessy, Marlene ^*, Pena, Rhoneil ^*, Quach, Phi ^*, Moffet, Andrew ^*, Nieves, Wildaliz ^*, Zhang, Ping ^*, Marcondes, Mario Q., Madakamutil, Loui ^*, Zalevsky, Jonathan ^*

Source: In Blood 13 November 2019 134 Supplement 1:5302-5302

This result is not displayed to guests.
Login for full access.

Dact1–3 mRNAs exhibit distinct expression domains during tooth development

Authors: Kettunen, Päivi, Kivimäe, Saul, Keshari, Pankaj, Klein, Ophir D., Cheyette, Benjamin N.R., Luukko, Keijo

Source: In Gene Expression Patterns 2010 10(2):140-143

This result is not displayed to guests.
Login for full access.

568. Characterization of Iduronidase-Expressing Monocyte Progenitor Cells for a Cell Based Therapy for Hurler Syndrome

Authors: Lee, Simon, Kivimäe, Saul, Szoka, Francis C.

Source: In Molecular Therapy May 2015 23 Supplement 1:S226-S227

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases.

Authors: Kivimäe, Saul, Xiao Yong Yang, Cheyette, Benjamin N. R.

Source: BMC Biochemistry; 2011, Vol. 12 Issue 1, p33-44, 12p

Subject Terms: SCAFFOLD proteins, AMINO acids, SERINE, DIMERIZATION, FRUIT flies