Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer

Authors: Antti Kiviaho, Sini K. Eerola, Heini M. L. Kallio, Maria K. Andersen, Miina Hoikka, Aliisa M. Tiihonen, Iida Salonen, Xander Spotbeen, Alexander Giesen, Charles T. A. Parker, Sinja Taavitsainen, Olli Hantula, Mikael Marttinen, Ismaïl Hermelo, Mazlina Ismail, Elise Midtbust, Maximilian Wess, Wout Devlies, Abhibhav Sharma, Sebastian Krossa, Tomi Häkkinen, Ebrahim Afyounian, Katy Vandereyken, Sam Kint, Juha Kesseli, Teemu Tolonen, Teuvo L. J. Tammela, Trond Viset, Øystein Størkersen, Guro F. Giskeødegård, Morten B. Rye, Teemu Murtola, Andrew Erickson, Leena Latonen, G. Steven Bova, Ian G. Mills, Steven Joniau, Johannes V. Swinnen, Thierry Voet, Tuomas Mirtti, Gerhardt Attard, Frank Claessens, Tapio Visakorpi, Kirsi J. Rautajoki, May-Britt Tessem, Alfonso Urbanucci, Matti Nykter

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/1ebb45b1d7aa49d7b63f03831144be68

Previously reported CCDC26 risk variant and novel germline variants in GALNT13, AR, and MYO10 associated with familial glioma in Finland

Authors: Riikka Nurminen, Ebrahim Afyounian, Niina Paunu, Riku Katainen, Mari Isomäki, Anssi Nurminen, Mauro Scaravilli, Jenni Tolppanen, Vidal Fey, Anni Kivinen, Pauli Helén, Niko Välimäki, Juha Kesseli, Lauri A. Aaltonen, Hannu Haapasalo, Matti Nykter, Kirsi J. Rautajoki

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3f05e1aae8db4dccab392f0bae132f55

Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting

Authors: Kirsi J. Rautajoki, Serafiina Jaatinen, Anja Hartewig, Aliisa M. Tiihonen, Matti Annala, Iida Salonen, Masi Valkonen, Vili Simola, Elisa M. Vuorinen, Anni Kivinen, Minna J. Rauhala, Riikka Nurminen, Kendra K. Maass, Sirpa-Liisa Lahtela, Arja Jukkola, Olli Yli-Harja, Pauli Helén, Kristian W. Pajtler, Pekka Ruusuvuori, Joonas Haapasalo, Wei Zhang, Hannu Haapasalo, Matti Nykter

Source: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)

Subject Terms: Diffuse glioma, Secondary glioblastoma, Non-homologous end-joining, Microhomology-mediated end-joining, Homologous recombination repair, Longitudinal analysis, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/93bb5201f4a448cca5fb328e55e9e60a

Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection

Authors: Jake Lin, Elaheh Moradi, Karoliina Salenius, Suvi Lehtipuro, Tomi Häkkinen, Jutta E. Laiho, Sami Oikarinen, Sofia Randelin, Hemang M. Parikh, Jeffrey P. Krischer, Jorma Toppari, Åke Lernmark, Joseph F. Petrosino, Nadim J. Ajami, Jin-Xiong She, William A. Hagopian, Marian J. Rewers, Richard E. Lloyd, Kirsi J. Rautajoki, Heikki Hyöty, Matti Nykter, the TEDDY Study Group

Source: Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/80ebd0159183481dafbd9063fd5905f9

PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas

Authors: Kirsi J. Rautajoki, Serafiina Jaatinen, Aliisa M. Tiihonen, Matti Annala, Elisa M. Vuorinen, Anni Kivinen, Minna J. Rauhala, Kendra K. Maass, Kristian W. Pajtler, Olli Yli-Harja, Pauli Helén, Joonas Haapasalo, Hannu Haapasalo, Wei Zhang, Matti Nykter

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/217af1ece6ce40dc840de8b5664b04d5