Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection

Authors: Koenecke, Allison, Powell, Michael, Xiong, Ruoxuan, Shen, Zhu, Fischer, Nicole, Huq, Sakibul, Khalafallah, Adham M., Trevisan, Marco, Sparen, Pär, Carrero, Juan J, Nishimura, Akihiko, Caffo, Brian, Stuart, Elizabeth A., Bai, Renyuan, Staedtke, Verena, Thomas, David L., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Bettegowda, Chetan, Konig, Maximilian F., Mensh, Brett, Vogelstein, Joshua T., Athey, Susan

Source: Elife 10 (2021): e61700

Subject Terms: Quantitative Biology - Tissues and Organs, Quantitative Biology - Quantitative Methods

Access URL: http://arxiv.org/abs/2004.10117

TCR-mimic bispecific antibodies to target the HIV-1 reservoir

Authors: Sengupta, Srona, Board, Nathan L., Wu, Fengting, Moskovljevic, Milica, Douglass, Jacqueline, Zhang, Josephine, Reinhold, Bruce R., Duke-Cohan, Jonathan, Yu, Jeanna, Reed, Madison C., Tabdili, Yasmine, Azurmendi, Aitana, Fray, Emily J., Zhang, Hao, Hsiue, Emily Han-Chung, Jenike, Katharine, Ho, Ya-Chi, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Siliciano, Janet D., Nasseri, Scheherazade Sadegh-, Reinherz, Ellis L., Siliciano, Robert F.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Apr 01. 119(15), 1-12.

Access URL: https://www.jstor.org/stable/27151816

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape.

Authors: Cook, Ashley L., Sur, Surojit, Dobbyn, Laura, Watson, Evangeline, Cohen, Joshua D., Ptak, Blair, Bum Seok Lee, Paul, Suman, Hsiue, Emily, Popoli, Maria, Vogelstein, Bert, Papadopoulos, Nickolas, Bettegowda, Chetan, Gabrielson, Kathy, Zhou, Shibin, Kinzler, Kenneth W., Wyhs, Nicolas

Source: eLife; 2/17/2025, p1-32, 32p

Targeting loss of heterozygosity for cancer-specific immunotherapy

Authors: Hwang, Michael S., Mog, Brian J., Douglass, Jacqueline, Pearlman, Alexander H., Hsiue, Emily Han-Chung, Paul, Suman, DiNapoli, Sarah R., Konig, Maximilian F., Pardoll, Drew M., Gabelli, Sandra B., Bettegowda, Chetan, Papadopoulos, Nickolas, Vogelstein, Bert, Zhou, Shibin, Kinzler, Kenneth W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(12), 1-10.

Access URL: https://www.jstor.org/stable/27039563

QnAs with Kenneth W. Kinzler

Authors: Ravindran, Sandeep, Kinzler, Kenneth W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(12), 1-2.

Access URL: https://www.jstor.org/stable/27039554

Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer: 5-year outcomes of the randomized DYNAMIC trial

Authors: Tie, Jeanne, Wang, Yuxuan, Lo, Serigne N., Lahouel, Kamel, Cohen, Joshua D., Wong, Rachel, Shapiro, Jeremy D., Harris, Samuel J., Khattak, Adnan, Burge, Matthew E., Lee, Margaret, Harris, Marion, McLachlan, Sue-Anne, Horvath, Lisa, Karapetis, Christos, Shannon, Jenny, Singh, Madhu, Yip, Desmond, Ananda, Sumitra, Underhill, Craig, Ptak, Janine, Silliman, Natalie, Dobbyn, Lisa, Popoli, Maria, Papadopoulos, Nickolas, Tomasetti, Cristian, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter

Source: Nature Medicine; 20250101, Issue: Preprints p1-10, 10p

Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett’s Esophagus

Authors: Douville, Christopher, Moinova, Helen R., Thota, Prashanthi N., Shaheen, Nicholas J., Iyer, Prasad G., Canto, Marcia Irene, Wang, Jean S., Dumot, John A., Faulx, Ashley, Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert, Markowitz, Sanford D., Bettegowda, Chetan, Willis, Joseph E., Chak, Amitabh

Source: In Gastroenterology May 2021 160(6):2043-2054

Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies

Authors: Tie, Jeanne, Cohen, Joshua D., Lo, Serigne N., Wang, Yuxuan, Li, Lu, Christie, Michael, Lee, Margaret, Wong, Rachel, Kosmider, Suzanne, Skinner, Iain, Wong, Hui Li, Lee, Belinda, Burge, Matthew E., Yip, Desmond, Karapetis, Christos S., Price, Timothy J., Tebbutt, Niall C., Haydon, Andrew M., Ptak, Janine, Schaeffer, Mary J., Silliman, Natalie, Dobbyn, Lisa, Popoli, Maria, Tomasetti, Cristian, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter

Source: International journal of cancer. 148(4):1014-1026

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111853847.0x000001&indx=1&recIds=ETOCvdc_100111853847.0x000001

Assessing aneuploidy with repetitive element sequencing

Authors: Douville, Christopher, Cohen, Joshua D., Ptak, Janine, Popoli, Maria, Schaefer, Joy, Silliman, Natalie, Dobbyn, Lisa, Schoen, Robert E., Tie, Jeanne, Gibbs, Peter, Goggins, Michael, Wolfgang, Christopher L., Wang, Tian-Li, Shih, Ie-Ming, Karchin, Rachel, Lennon, Anne Marie, Hruban, Ralph H., Tomasetti, Cristian, Bettegowda, Chetan, Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar 01. 117(9), 4858-4863.

Access URL: https://www.jstor.org/stable/26929182

Revisiting the tumorigenesis timeline with a data-driven generative model

Authors: Lahouel, Kamel, Younes, Laurent, Danilova, Ludmila, Giardiello, Francis M., Hruban, Ralph H., Groopman, John, Kinzler, Kenneth W., Vogelstein, Bert, Geman, Donald, Tomasetti, Cristian

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jan . 117(2), 857-864.

Access URL: https://www.jstor.org/stable/26896952

An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation

Authors: Miller, Michelle S., Douglass, Jacqueline, Hwang, Michael S., Skora, Andrew D., Murphy, Michael, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Gabelli, Sandra B. ^**

Source: In Journal of Biological Chemistry 13 December 2019 294(50):19322-19334

Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology

Authors: Rodriguez Pena, Maria Del Carmen, Springer, Simeon U., Taheri, Diana, Li, Lu, Tregnago, Aline C., Eich, Marie-Lisa, Eltoum, Isam-Eldin A., VandenBussche, Christopher J., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Netto, George J.

Source: Virchows Archiv. 476(3):423-429

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168023055.0x000001&indx=1&recIds=ETOCvdc_100168023055.0x000001

Accumulation of driver and passenger mutations during tumor progression

Authors: Bozic, Ivana, Antal, Tibor, Ohtsuki, Hisashi, Carter, Hannah, Kim, Dewey, Chen, Sining, Karchin, Rachel, Kinzler, Kenneth W., Vogelstein, Bert, Nowak, Martin A.

Source: PNAS 107, 18545 (2010)

Subject Terms: Quantitative Biology - Populations and Evolution

Access URL: http://arxiv.org/abs/0912.1627

Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations

Authors: Palsgrove, Doreen N., Taheri, Diana, Springer, Simeon U., Cowan, Morgan, Guner, Gunes, Mendoza Rodriguez, Maria A., Rodriguez Pena, Maria Del Carmen, Wang, Yuxuan, Kinde, Isaac, Ricardo, Bernardo F.P., Cunha, Isabela, Fujita, Kazutoshi, Ertoy, Dilek, Kinzler, Kenneth W., Bivalacqua, Trinity J., Papadopoulos, Nickolas, Vogelstein, Bert, Netto, George J.

Source: In Human Pathology March 2019 85:1-9

Minimal functional driver gene heterogeneity among untreated metastases

Authors: Reiter, Johannes G., Makohon-Moore, Alvin P., Gerold, Jeffrey M., Heyde, Alexander, Attiyeh, Marc A., Kohutek, Zachary A., Tokheim, Collin J., Brown, Alexia, DeBlasio, Rayne M., Niyazov, Juliana, Zucker, Amanda, Karchin, Rachel, Kinzler, Kenneth W., Iacobuzio-Donahue, Christine A., Vogelstein, Bert, Nowak, Martin A.

Source: Science, 2018 Sep 01. 361(6406), 1033-1037.

Access URL: https://www.jstor.org/stable/26505312

Genetic progression and the waiting time to cancer

Authors: Beerenwinkel, Niko, Antal, Tibor, Dingli, David, Traulsen, Arne, Kinzler, Kenneth W., Velculescu, Victor E., Vogelstein, Bert, Nowak, Martin A.

Source: PLoS Comput Biol 3(11): e225 (2007)

Subject Terms: Quantitative Biology - Populations and Evolution, Quantitative Biology - Quantitative Methods

Access URL: http://arxiv.org/abs/0707.3770

Detection and Quantification of Mutations in the Plasma of Patients with Colorectal Tumors

Authors: Li, Meng, Dressman, Devin, He, Yiping, Shen, Dong, Szabo, Steve, Goodman, Steven N., Juhl, Hartmut, Kinzler, Kenneth W., Vogelstein, Bert

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Nov 01. 102(45), 16368-16373.

Access URL: https://www.jstor.org/stable/4152432

Imaging Bacterial Infections with Radiolabeled 1-(2′-Deoxy-2′-Fluoro-β-D-Arabinofuranosyl)-5-Iodouracil

Authors: Bettegowda, Chetan, Foss, Catherine A., Cheong, Ian, Wang, Yuchuan, Diaz, Luis, Agrawal, Nishant, Fox, James, Dick, James, Dang, Long H., Zhou, Shibin, Kinzler, Kenneth W., Vogelstein, Bert, Pomper, Martin G.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Jan . 102(4), 1145-1150.

Access URL: https://www.jstor.org/stable/3374392

Application of Deep Learning to Pancreatic Cancer Detection: Lessons Learned From Our Initial Experience

Authors: Chu, Linda C., Park, Seyoun, Kawamoto, Satomi, Wang, Yan, Zhou, Yuyin, Shen, Wei, Zhu, Zhuotun, Xia, Yingda, Xie, Lingxi, Liu, Fengze, Yu, Qihang, Fouladi, Daniel F., Shayesteh, Shahab, Zinreich, Eva, Graves, Jefferson S., Horton, Karen M., Yuille, Alan L., Hruban, Ralph H., Kinzler, Kenneth W., Vogelstein, Bert, Fishman, Elliot K.

Source: Journal of the American College of Radiology. 16(PB):1338-1342

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087514260.0x000001&indx=1&recIds=ETOCvdc_100087514260.0x000001

Genomic landscape and evolutionary trajectories of ovarian cancer precursor lesions

Authors: Wu, Ren‐Chin, Wang, Pei, Lin, Shiou‐Fu, Zhang, Ming, Song, Qianqian, Chu, Tiffany, Wang, Brant G, Kurman, Robert J, Vang, Russell, Kinzler, Kenneth, Tomasetti, Cristian, Jiao, Yuchen, Shih, Ie‐Ming, Wang, Tian‐Li

Source: Journal of pathology. 248(1):41-50

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084201766.0x000001&indx=1&recIds=ETOCvdc_100084201766.0x000001