Safety and toxicity of Iopofosine I 131 (CLR 131) with external beam radiation therapy in recurrent or metastatic head and neck cancer: results of a phase 1 single-centre, open-label, single-arm, dose escalation and dose expansion study

Authors: Bruce, Justine Yang ^{a, ∗}, Burr, Adam ^b, Kimple, Randall J. ^b, Adam, David P. ^c, Yu, Menggang ^d, Piaskowski, Shari M. ^b, Glazer, Tiffany A. ^e, Hill, Patrick ^b, Hartig, Gregory K. ^e, McCulloch, Timothy M. ^e, Wieland, Aaron M. ^e, Trask, Diana ^b, Oliver, Kate ^f, Longcor, Jarrod ^f, Rogus-Pulia, Nicole ^g, Cho, Steve Y. ^h, Bednarz, Bryan ^{b, i}, Harari, Paul M. ^b

Source: In eBioMedicine January 2025 111

Multifunctional dendrimer-peptide conjugates for MET receptor-specific imaging of cancer cells

Authors: Lee, Jin Woong, Nickel, Kwangok P., Minne, Rachel L., Jeffery, Justin J., Aluicio-Sarduy, Eduardo, Kim, Carter, Kim, DaWon, Rawding, Piper A., Poellmann, Michael J., Mamidi, Narsimha, Engle, Jonathan W., Lee, Jung Heon, Park, Hansoo, Hernandez, Reinier, Kimple, Randall J., Baschnagel, Andrew M., Hong, Seungpyo

Source: In Nano Today December 2024 59

Challenges and opportunities for early phase clinical trials of novel drug–radiotherapy combinations: recommendations from NRG Oncology, the American Society for Radiation Oncology (ASTRO), the American College of Radiology (ACR), the Sarah Cannon Research Institute, and the American College of Radiation Oncology (ACRO)

Authors: Zumsteg, Zachary S ^*, Sheth, Siddharth, Jabbour, Salma K, Patel, Krishnan R, Kimple, Randall J, Williams, Terence M, Xu-Welliver, Meng, Torres-Saavedra, Pedro A, Monjazeb, Arta M, Mayadev, Jyoti, Finkelstein, Steven E, Buatti, John M, Patel, Sandip P, Lin, Steven H

Source: In The Lancet Oncology October 2024 25(10):e489-e500

Genomic and Immune Landscape Comparison of MET Exon 14 Skipping and MET-Amplified Non-small Cell Lung Cancer

Authors: Minne, Rachel L., Luo, Natalie Y., Traynor, Anne M., Huang, Minxuan, DeTullio, Luisina, Godden, Jen, Stoppler, Melissa, Kimple, Randall J., Baschnagel, Andrew M.

Source: In Clinical Lung Cancer September 2024 25(6):567-576

An algorithm for standardization of tumor Infiltrating lymphocyte evaluation in head and neck cancers

Authors: Xirou, Vasiliki, Moutafi, Myrto, Bai, Yalai, Nwe Aung, Thazin, Burela, Sneha, Liu, Matthew, Kimple, Randall J., Shabbir Ahmed, Fahad, Schultz, Bryant, Flieder, Douglas, Connolly, Denise C., Psyrri, Amanda, Burtness, Barbara, Rimm, David L.

Source: In Oral Oncology May 2024 152

Functionality of bone marrow mesenchymal stromal cells derived from head and neck cancer patients – A FDA-IND enabling study regarding MSC-based treatments for radiation-induced xerostomia

Authors: Blitzer, Grace C., Paz, Cristina, Glassey, Annemarie, Ganz, Olga R., Giri, Jayeeta, Pennati, Andrea, Meyers, Ross O., Bates, Amber M., Nickel, Kwangok P, Weiss, Marissa, Morris, Zachary S., Mattison, Ryan J., McDowell, Kimberly A., Croxford, Emma, Chappell, Richard J., Glazer, Tiffany A., Rogus-Pulia, Nicole M., Galipeau, Jacques, Kimple, Randall J.

Source: In Radiotherapy and Oncology March 2024 192

Interstitial Brachytherapy for Lip Cancer: Technical Aspects to Individualize Treatment Approach and Optimize Outcomes

Authors: Merfeld, Emily C., Witek, Matthew E., Francis, David M., Burr, Adam R., Wallace, Charles R., Kuczmarska-Haas, Aleksandra, Lamichhane, Narottam, Kimple, Randall J., Glazer, Tiffany A., Wieland, Aaron M., McCulloch, Timothy M., Hartig, Gregory K., Harari, Paul M.

Source: Practical radiation oncology. 13(4):340-345

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193605004.0x000001&indx=1&recIds=ETOCvdc_100193605004.0x000001

Radiation Sensitivity: The Rise of Predictive Patient-Derived Cancer Models

Authors: Berube, Liliana L, Nickel, Kwang-ok P, Iida, Mari, Ramisetty, Sravani, Kulkarni, Prakash, Salgia, Ravi, Wheeler, Deric L, Kimple, Randall J

Source: Seminars in radiation oncology. 33(3):279-286

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193412067.0x000001&indx=1&recIds=ETOCvdc_100193412067.0x000001

Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Foundation 3504

Authors: Gillison, Maura L., Ferris, Robert L., Harris, Jonathan, Colevas, A. Dimitrios, Mell, Loren K., Kong, Christina, Jordan, Richard C., Moore, Kevin L., Truong, Minh-Tam, Kirsch, Claudia, Chakravarti, Arnab, Blakaj, Dukagjin M., Clump, David A., Ohr, James P., Deeken, John F., Gensheimer, Michael F., Saba, Nabil F., Dorth, Jennifer A., Rosenthal, David I., Leidner, Rom S., Kimple, Randall J., Machtay, Mitchell, Curran, Walter J., Torres-Saavedra, Pedro, Le, Quynh Thu

Source: International journal of radiation oncology, biology, physics. 115(4):847-860

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184087905.0x000001&indx=1&recIds=ETOCvdc_100184087905.0x000001

Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment

Authors: Poellmann, Michael J., Bu, Jiyoon, Kim, DaWon, Iida, Mari, Hong, Heejoo, Wang, Andrew Z., Wheeler, Deric L., Kimple, Randall J., Hong, Seungpyo

Source: In Cancer Letters 28 May 2023 562

Bimodal liquid biopsy for cancer immunotherapy based on peptide engineering and nanoscale analysis

Authors: Bu, Jiyoon, Jeong, Woo-jin, Jafari, Roya, Kubiatowicz, Luke J., Nair, Ashita, Poellmann, Michael J., Hong, Rachel S., Liu, Elizabeth W., Owen, Randall H., Rawding, Piper A., Hopkins, Caroline M., Kim, DaWon, George, Daniel J., Armstrong, Andrew J., Král, Petr, Wang, Andrew Z., Bruce, Justine, Zhang, Tian, Kimple, Randall J., Hong, Seungpyo

Source: In Biosensors and Bioelectronics 1 October 2022 213

Radiation-Therapy Related Salivary Dysfunction.

Authors: Blitzer, Grace C., Paz, Cristina, McCoy, Sara S., Kimple, Randall J.

Source: Seminars in Radiation Oncology; Apr2025, Vol. 35 Issue 2, p278-284, 7p

Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer

Authors: Carper, Miranda B., Goel, Saumya, Zhang, Anna M., Damrauer, Jeffrey S., Cohen, Stephanie, Zimmerman, Matthew P., Gentile, Gabrielle M., Parag-Sharma, Kshitij, Murphy, Ryan M., Sato, Kotaro, Nickel, Kwangok P., Kimple, Randall J., Yarbrough, Wendell G., Amelio, Antonio L.

Source: In Neoplasia July 2022 29

Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction (MARSH): Study protocol for a phase 1 dose-escalation trial of patients with xerostomia after radiation therapy for head and neck cancer: MARSH: Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction

Authors: Blitzer, Grace C., Rogus-Pulia, Nicole M., Mattison, Ryan J., Varghese, Tomy, Ganz, Olga, Chappell, Richard, Galipeau, Jacques, McDowell, Kimberly A., Meyers, Ross O., Glazer, Tiffany A., Kimple, Randall J.

Source: In Cytotherapy May 2022 24(5):534-543

Autophagy awakens—the myriad roles of autophagy in head and neck cancer development and therapeutic response

Authors: Bradley, Samantha T., Lee, Yong‐Syu, Gurel, Zafer, Kimple, Randall J.

Source: Molecular carcinogenesis. 61(2):243-253

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139523798.0x000001&indx=1&recIds=ETOCvdc_100139523798.0x000001

Prospective Study of PET/MRI Tumor Response During Chemoradiotherapy for Patients With Low-risk and Intermediate-risk p16-positive Oropharynx Cancer

Authors: Witek, Matthew E., Kimple, Randall J., Avey, Gregory D., Burr, Adam R., Chandereng, Thevaa, Yu, Menggang, Hu, Rong, Wieland, Aaron M., Labby, Zacariah E., Bruce, Justine Y., Brower, Jeffrey V., Hartig, Gregory K., Harari, Paul M.

Source: American journal of clinical oncology. 45(5):202-207

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194439536.0x000001&indx=1&recIds=ETOCvdc_100194439536.0x000001

Defining high‐risk elective contralateral neck radiation volumes for oropharynx cancer

Authors: Witek, Matthew E., Woody, Neil M., Musunuru, Hima B., Hill, Patrick M., Yadav, Poonam, Burr, Adam R., Ko, Huaising C., Ross, Richard B., Kimple, Randall J., Harari, Paul M.

Source: Head & neck. 44(2):317-324

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138908707.0x000001&indx=1&recIds=ETOCvdc_100138908707.0x000001

Quantification of very late xerostomia in head and neck cancer patients after irradiation

Authors: Blitzer, Grace C., Rogus‐Pulia, Nicole M., Paz, Cristina, Nickel, Kwangok P., Cannaday, Vanessa L., Kelm‐Nelson, Cynthia A., Sudakaran, Sailendharan, Chappell, Richard J., Glazer, Tiffany, Kimple, Randall J.

Source: Laryngoscope investigative otolaryngology. 7(4):1018-1024

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100158427515.0x000001&indx=1&recIds=ETOCvdc_100158427515.0x000001

Biology of HPV Mediated Carcinogenesis and Tumor Progression

Authors: Cosper, Pippa F. ^*, Bradley, Samantha ^*, Luo, Qianyun ^*, Kimple, Randall J. ^*

Source: In Seminars in Radiation Oncology October 2021 31(4):265-273

Immunotherapy in Head and Neck Cancer—Ready for Prime Time or More Research Needed?

Authors: Karam, Sana D., Anderson, Carryn M., Ma, Daniel, Chua, Melvin L.K., Kimple, Randall J.

Source: International journal of radiation oncology, biology, physics. 109(3):647-650

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136470384.0x000001&indx=1&recIds=ETOCvdc_100136470384.0x000001