Sertraline/chloroquine combination therapy to target hypoxic and immunosuppressive serine/glycine synthesis-dependent glioblastomas

Authors: Anaís Sánchez-Castillo, Kim G. Savelkouls, Alessandra Baldini, Judith Hounjet, Pierre Sonveaux, Paulien Verstraete, Kim De Keersmaecker, Barbara Dewaele, Benny Björkblom, Beatrice Melin, Wendy Y. Wu, Rickard L. Sjöberg, Kasper M. A. Rouschop, Martijn P. G. Broen, Marc Vooijs, Kim R. Kampen

Source: Oncogenesis, Vol 13, Iss 1, Pp 1-18 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2157-9024

Access URL: https://doaj.org/article/d61b57eb4ce140da832cf94a49f0efd8

Cancer EV stimulate endothelial glycolysis to fuel protein synthesis via mTOR and AMPKα activation

Authors: Joël E. J. Beaumont, Lydie M. O. Barbeau, Jinzhe Ju, Kim G. Savelkouls, Freek G. Bouwman, Marijke I. Zonneveld, Annelies Bronckaers, Kim R. Kampen, Tom G. H. Keulers, Kasper M. A. Rouschop

Source: Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)

Subject Terms: angiogenesis, extracellular vesicles, hypoxia, metabolism, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/ec4b00231fe04dc18ed39d6c447f3218

Secretion of pro‐angiogenic extracellular vesicles during hypoxia is dependent on the autophagy‐related protein GABARAPL1

Authors: Tom G. Keulers, Sten F. Libregts, Joel E.J. Beaumont, Kim G. Savelkouls, Johan Bussink, Hans Duimel, Ludwig Dubois, Marijke I. Zonneveld, Carmen López‐Iglesias, Karel Bezstarosti, Jeroen A. Demmers, Marc Vooijs, Marca Wauben, Kasper M.A. Rouschop

Source: Journal of Extracellular Vesicles, Vol 10, Iss 14, Pp n/a-n/a (2021)

Subject Terms: autophagy, exosomes, extracellular vesicles, GABARAPL1, hypoxia, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/af6b9ede953b475aa1ad89c65bcf4ab4

MAP1LC3C repression reduces CIITA- and HLA class II expression in non-small cell lung cancer.

Authors: Lydie M O Barbeau, Nicky A Beelen, Kim G Savelkouls, Tom G H Keulers, Lotte Wieten, Kasper M A Rouschop

Source: PLoS ONE, Vol 20, Iss 2, p e0316716 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/89778b76bd294f19b72e0c4130cde654