Engineering therapeutic phages for enhanced antibacterial efficacy

Authors: Meile, Susanne, Du, Jiemin, Dunne, Matthew, Kilcher, Samuel, Loessner, Martin J

Source: In Current Opinion in Virology February 2022 52:182-191

Enhancing phage therapy through synthetic biology and genome engineering

Authors: Lenneman, Bryan R, Fernbach, Jonas, Loessner, Martin J, Lu, Timothy K, Kilcher, Samuel

Source: In Current Opinion in Biotechnology April 2021 68:151-159

Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes

Authors: Osuna, Beatriz A., Karambelkar, Shweta, Mahendra, Caroline, Christie, Kathleen A., Garcia, Bianca, Davidson, Alan R., Kleinstiver, Benjamin P., Kilcher, Samuel, Bondy-Denomy, Joseph

Source: In Cell Host & Microbe 8 July 2020 28(1):31-40

Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins

Authors: Dunne, Matthew, Rupf, Beatrice, Tala, Marc, Qabrati, Xhem, Ernst, Patrick, Shen, Yang, Sumrall, Eric, Heeb, Laura, Plückthun, Andreas, Loessner, Martin J., Kilcher, Samuel

Source: In Cell Reports 29 October 2019 29(5):1336-1350

Engineering Bacteriophages as Versatile Biologics

Authors: Kilcher, Samuel, Loessner, Martin J.

Source: In Trends in Microbiology April 2019 27(4):355-367

Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility

Authors: Beerli, Corina, Yakimovich, Artur, Kilcher, Samuel, Reynoso, Glennys, Fläschner, Gotthold, Müller, Daniel, Hickman, Heather, Mercer, Jason

Source: Nature microbiology. 4(2):216-225

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111628254.0x000001&indx=1&recIds=ETOCvdc_100111628254.0x000001

RNAi-Mediated Depletion of Poxvirus Proteins

Authors: Martin, Caroline, Kilcher, Samuel

Source: Methods in molecular biology. 2023:119-130

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620729575&indx=1&recIds=ETOCRN620729575

Cross-genus rebooting of custom-made, synthetic bacteriophage genomes in L-form bacteria

Authors: Kilcher, Samuel, Studer, Patrick, Muessner, Christina, Klumpp, Jochen, Loessner, Martin J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Jan . 115(3), 567-572.

Access URL: https://www.jstor.org/stable/26506382

Proteotype profiling unmasks a viral signalling network essential for poxvirus assembly and transcriptional competence

Authors: Novy, Karel, Kilcher, Samuel, Omasits, Ulrich, Bleck, Christopher, Beerli, Corina, Vowinckel, Jakob, Martin, Caroline, Syedbasha, Mohammedyaseen, Maiolica, Alessio, White, Ian, Mercer, Jason, Wollscheid, Bernd

Source: Nature microbiology. 3(5):588-599

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131597997.0x000001&indx=1&recIds=ETOCvdc_100131597997.0x000001

Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility

Authors: Beerli, Corina, Yakimovich, Artur, Kilcher, Samuel, Reynoso, Glennys V., Fläschner, Gotthold, Müller, Daniel J., Hickman, Heather D., Mercer, Jason

Source: Nature microbiology. 4(2):216-225

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130017543.0x000001&indx=1&recIds=ETOCvdc_100130017543.0x000001

DNA virus uncoating

Authors: Kilcher, Samuel, Mercer, Jason

Source: In Virology May 2015 479-480:578-590

Next generation approaches to study virus entry and infection

Authors: Kilcher, Samuel, Mercer, Jason

Source: In Current Opinion in Virology February 2014 4:8-14

Tracking Viral Genomes in Host Cells at Single-Molecule Resolution

Authors: Wang, I-Hsuan, Suomalainen, Maarit, Andriasyan, Vardan, Kilcher, Samuel, Mercer, Jason, Neef, Anne, Luedtke, Nathan W., Greber, Urs F.

Source: In Cell Host & Microbe 16 October 2013 14(4):468-480

Critical Anti-CRISPR Locus Repression by a Bi-functional Cas9 Inhibitor

Authors: Osuna, Beatriz A., Karambelkar, Shweta, Mahendra, Caroline, Sarbach, Anne, Johnson, Matthew C., Kilcher, Samuel, Bondy-Denomy, Joseph

Source: Cell host & microbe. 28(1):23-30.e5

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116044243.0x000001&indx=1&recIds=ETOCvdc_100116044243.0x000001

Enhancing bacteriophage therapeutics through in situ production and release of heterologous antimicrobial effectors.

Authors: Du, Jiemin, Meile, Susanne, Baggenstos, Jasmin, Jäggi, Tobias, Piffaretti, Pietro, Hunold, Laura, Matter, Cassandra I., Leitner, Lorenz, Kessler, Thomas M., Loessner, Martin J., Kilcher, Samuel, Dunne, Matthew

Source: Nature Communications; 7/20/2023, Issue 1, p1-10, 10p

Subject Terms: BACTERIOPHAGES, ESCHERICHIA coli, URINARY tract infections, COMPANION diagnostics, DRUG resistance in bacteria, ENGINEERS

MP02-08 RAPID DETECTION OF BACTERIAL UTIS VIA REPORTER PHAGE-BASED BIOLUMINESCENCE ASSAY

Authors: Leitner, Lorenz, Du, Jiemin, Meile, Susanne, McCallin, Shawna, Neumeier, Vera, Kessler, Thomas M., Loessner, Martin J., Kilcher, Samuel, Dunne, Matthew

Source: Journal of urology. 207(5):e13-e13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165016679.0x000001&indx=1&recIds=ETOCvdc_100165016679.0x000001

Phage resistance at the cost of virulence: Listeria monocytogenes serovar 4b requires galactosylated teichoic acids for InlB-mediated invasion.

Authors: Sumrall, Eric T.¹, Shen, Yang¹, yang.shen@hest.ethz.ch, Keller, Anja P.¹, Rismondo, Jeanine², Pavlou, Maria³, Eugster, Marcel R.¹, Boulos, Samy¹, Disson, Olivier^4,5, Thouvenot, Pierre^4,5, Kilcher, Samuel¹, Wollscheid, Bernd³, Cabanes, Didier⁶, Lecuit, Marc^4,5,7, Gründling, Angelika², Loessner, Martin J.¹, martin.loessner@ethz.ch

Source: PLoS Pathogens; 10/7/2019, Vol. 15 Issue 10, p1-29, 29p

Brochothrix thermosphacta Bacteriophages Feature Heterogeneous and Highly Mosaic Genomes and Utilize Unique Prophage Insertion Sites.

Authors: Kilcher, Samuel, Loessner, Martin J., Klumpp, Jochen

Source: Journal of Bacteriology; October 2010, Vol. 192 Issue 20, p5441-5453, 13p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.