Refining Diagnostic Subtypes of Peripheral T-Cell Lymphoma Using a Multiparameter Approach

Authors: Amador, Catalina ^{a, ∗}, Weisenburger, Dennis D. ^b, Gomez, Ana ^a, Bouska, Alyssa ^b, Alshomrani, Ahmad ^b, Sharma, Sunandini ^b, Shah, Ab Rauf ^b, Greiner, Timothy C. ^b, Vega, Francisco ^c, Rosenwald, Andreas ^{d, e}, Ott, German ^{f, g}, Feldman, Andrew L. ^h, Jaffe, Elaine S. ⁱ, Ozkaya, Neval ⁱ, Ondrejka, Sarah L. ^j, Cook, James R. ^j, Raess, Philipp W. ^k, Savage, Kerry J. ^l, Slack, Graham W. ^l, Song, Joo Y. ^m, Scott, David W. ^l, Campo, Elias ^{n, o}, Rimsza, Lisa M. ^p, Khoury, Joseph D. ^b, Staudt, Louis M. ^q, Chan, Wing C. ^m, Iqbal, Javeed ^{b, ∗}

Source: In Modern Pathology February 2025 38(2)

Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms

Authors: Chen, Pingjun, Aminu, Muhammad, Hussein, Siba El, Khoury, Joseph D., Wu, Jia

Subject Terms: Quantitative Biology - Quantitative Methods, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning, Electrical Engineering and Systems Science - Image and Video Processing, 68T01 (Primary), I.2.10

Access URL: http://arxiv.org/abs/2106.16174

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice

Authors: Pourebrahim, Rasoul, Montoya, Rafael Heinz, Akiyama, Hiroki, Ostermann, Lauren, Khazaei, Shayuan, Muftuoglu, Muharrem, Baran, Natalia, Zhao, Ran, Lesluyes, Tom, Liu, Bin, Khoury, Joseph D., Gagea, Mihai, Van Loo, Peter, Andreeff, Michael

Source: In Cell Reports Medicine 21 May 2024 5(5)

Aleukemic Chronic Myeloid Leukemia Without Neutrophilia and Thrombocytosis: A Report From the BCR::ABL1 Pathology Group

Authors: Rivera, Daniel, Cui, Wei, Gao, Juehua, Peker, Deniz, Zhang, Qian-Yun, Dewar, Rajan, Qiu, Lianqun, Konoplev, Sergej, Hu, Zhihong, Sasaki, Koji, Hu, Aileen Y., E, Shuyu, Liu, Meng, Fang, Hong, Wang, Wei, Tang, Guilin, Apperley, Jane F., Hochhaus, Andreas, Cortes, Jorge E., Khoury, Joseph D., Medeiros, L. Jeffrey, Jabbour, Elias, Hu, Shimin

Source: In Modern Pathology February 2024 37(2)

Fifth Edition of the World Health Classification of Tumors of the Hematopoietic and Lymphoid Tissue: Myeloid Neoplasms

Authors: Loghavi, Sanam, Kanagal-Shamanna, Rashmi, Khoury, Joseph D., Medeiros, L. Jeffrey, Naresh, Kikkeri N., Nejati, Reza, Patnaik, Mrinal M.

Source: In Modern Pathology February 2024 37(2)

Myelodysplastic neoplasms evolving from inherited bone marrow failure syndromes / germline predisposition syndromes: Back under the microscope

Authors: Elghetany, M. Tarek, Patnaik, Mrinal M., Khoury, Joseph D.

Source: In Leukemia Research February 2024 137

Pathomic Features Reveal Immune and Molecular Evolution From Lung Preneoplasia to Invasive Adenocarcinoma

Authors: Chen, Pingjun, Rojas, Frank R., Hu, Xin, Serrano, Alejandra, Zhu, Bo, Chen, Hong, Hong, Lingzhi, Bandyoyadhyay, Rukhmini, Aminu, Muhammad, Kalhor, Neda, Lee, J. Jack, El Hussein, Siba, Khoury, Joseph D., Pass, Harvey I., Moreira, Andre L., Velcheti, Vamsidhar, Sterman, Daniel H., Fukuoka, Junya, Tabata, Kazuhiro, Su, Dan, Ying, Lisha, Gibbons, Don L., Heymach, John V., Wistuba, Ignacio I., Fujimoto, Junya, Solis Soto, Luisa M., Zhang, Jianjun, Wu, Jia

Source: In Modern Pathology December 2023 36(12)

ZNF683 marks a CD8+ T cell population associated with anti-tumor immunity following anti-PD-1 therapy for Richter syndrome

Authors: Parry, Erin M., Lemvigh, Camilla K., Deng, Stephanie, Dangle, Nathan, Ruthen, Neil, Knisbacher, Binyamin A., Broséus, Julien, Hergalant, Sébastien, Guièze, Romain, Li, Shuqiang, Zhang, Wandi, Johnson, Connor, Long, Jaclyn M., Yin, Shanye, Werner, Lillian, Anandappa, Annabelle, Purroy, Noelia, Gohil, Satyen, Oliveira, Giacomo, Bachireddy, Pavan, Shukla, Sachet A., Huang, Teddy, Khoury, Joseph D., Thakral, Beenu, Dickinson, Michael, Tam, Constantine, Livak, Kenneth J., Getz, Gad, Neuberg, Donna, Feugier, Pierre, Kharchenko, Peter, Wierda, William, Olsen, Lars Rønn, Jain, Nitin, Wu, Catherine J.

Source: In Cancer Cell 9 October 2023 41(10):1803-1816

Immunophenotypic and genomic landscape of Richter transformation diffuse large B-cell lymphoma

Authors: El Hussein, Siba, Medeiros, L. Jeffrey, Lyapichev, Kirill A., Fang, Hong, Jelloul, Fatima Zahra, Fiskus, Warren, Chen, Jiansong, Wei, Peng, Schlette, Ellen, Xu, Jie, Li, Shaoying, Kanagal-Shamanna, Rashmi, Yang, Hong, Tang, Zhenya, Thakral, Beenu, Loghavi, Sanam, Jain, Nitin, Thompson, Philip A., Ferrajoli, Alessandra, Wierda, William G., Jabbour, Elias, Patel, Keyur P., Dabaja, Bouthaina S., Bhalla, Kapil N., Khoury, Joseph D.

Source: In Pathology June 2023 55(4):514-524

Ponatinib and blinatumomab for Philadelphia chromosome-positive acute lymphoblastic leukaemia: a US, single-centre, single-arm, phase 2 trial

Authors: Jabbour, Elias ^*, Short, Nicholas J, Jain, Nitin, Huang, Xuelin, Montalban-Bravo, Guillermo, Banerjee, Pinaki, Rezvani, Katayoun, Jiang, Xianli, Kim, Kun Hee, Kanagal-Shamanna, Rashmi, Khoury, Joseph D, Patel, Keyur, Kadia, Tapan M, Daver, Naval, Chien, Kelly, Alvarado, Yesid, Garcia-Manero, Guillermo, Issa, Ghayas C, Haddad, Fadi G, Kwari, Monica, Thankachan, Jennifer, Delumpa, Ricardo, Macaron, Walid, Garris, Rebecca, Konopleva, Marina, Ravandi, Farhad, Kantarjian, Hagop

Source: In The Lancet Haematology January 2023 10(1):e24-e34

Expression pattern and diagnostic utility of BCL11B in mature T- and NK-cell neoplasms

Authors: Fang, Hong, Khoury, Joseph D., Torres-Cabala, Carlos A., Ng, Siok Bian, Xu, Jie, El Hussein, Siba, Hu, Shimin, Vega, Francisco, Li, Shaoying, Tang, Zhenya, Tang, Guilin, Medeiros, L. Jeffrey, Wang, Wei

Source: In Pathology December 2022 54(7):893-899

Clinicopathologic spectrum of myeloid neoplasms with concurrent myeloproliferative neoplasm driver mutations and SRSF2 mutations

Authors: Tashakori, Mehrnoosh, Khoury, Joseph D., Routbort, Mark J., Patel, Keyur P., Wang, Sa A., OK, Chi Young, El-Hussein, Siba, Kanagal-Shamanna, Rashmi, Luthra, Rajyalakshmi, Hu, Shimin, Lin, Pei, Pemmaraju, Naveen, Bose, Prithviraj, Verstovsek, Srdan, Bueso-Ramos, Carlos E., Medeiros, L. Jeffrey, Loghavi, Sanam

Source: In Modern Pathology November 2022 35(11):1677-1683

CD123-directed allogeneic chimeric-antigen receptor T-cell therapy (CAR-T) in blastic plasmacytoid dendritic cell neoplasm (BPDCN): Clinicopathological insights

Authors: Pemmaraju, Naveen, Wilson, Nathaniel R., Senapati, Jayastu, Economides, Minas P., Guzman, Monica L., Neelapu, Sattva S., Kazemimood, Rossana, Davis, Richard Eric, Jain, Nitin, Khoury, Joseph D., Sugita, Mayumi, Cai, Tianyu, Smith, Julianne, Frattini, Mark G., Garton, Andrew, Roboz, Gail, Konopleva, Marina

Source: In Leukemia Research October 2022 121

Immunohistochemical loss of enhancer of Zeste Homolog 2 (EZH2) protein expression correlates with EZH2 alterations and portends a worse outcome in myelodysplastic syndromes

Authors: Sakhdari, Ali, Class, Caleb, Montalban-Bravo, Guillermo, Sasaki, Koji, Bueso-Ramos, Carlos E., Patel, Keyur P., Routbort, Mark J., Loghavi, Sanam, Ok, Chi Young, Quesada, Andres, Khoury, Joseph D., Konoplev, Sergej N., Kantarjian, Hagop P., Garcia-Manero, Guillermo, Medeiros, L. Jeffrey, Kanagal-Shamanna, Rashmi

Source: In Modern Pathology September 2022 35(9):1212-1219

The Heterogeneity of 13q Deletions in Chronic Lymphocytic Leukemia: Diagnostic Challenges and Clinical Implications.

Authors: Xia, Changqing, Liu, Guang, Liu, Jinglan, Ronaghy, Arash, Tadros, Saber, Wang, Wei, Fang, Hong, Zhang, Shanxiang, Khoury, Joseph D., Tang, Zhenya

Source: Genes; Mar2025, Vol. 16 Issue 3, p252, 23p

Subject Terms: CHRONIC lymphocytic leukemia, FLUORESCENCE in situ hybridization, GENE mapping, WESTERN countries, PROGNOSIS

An Incidental Finding of Gain of a Diminished Chromosome 12 Centromere in an Individual with Lymphocytosis: A Case Report and Clinical Implications in Cytogenetic Testing.

Authors: Xia, Changqing, Cannatella, Jeffrey J., Smith, Scott C., Althof, Pamela A., Koerselman, Haley, Hempel, Thomas, Jaworski, Erin E., Winkler, Lisa M., Spaulding, Joanna R., Pickering, Diane, Khoury, Joseph D., Tang, Zhenya

Source: Diagnostics (2075-4418); Mar2025, Vol. 15 Issue 5, p618, 10p

Subject Terms: FLUORESCENCE in situ hybridization, CHRONIC lymphocytic leukemia, CENTROMERE, CYTOGENETICS, KARYOTYPES

Artificial intelligence-assisted mapping of proliferation centers allows the distinction of accelerated phase from large cell transformation in chronic lymphocytic leukemia

Authors: El Hussein, Siba, Chen, Pingjun, Medeiros, L. Jeffrey, Hazle, John D., Wu, Jia, Khoury, Joseph D.

Source: In Modern Pathology August 2022 35(8):1121-1125

High-sensitivity next-generation sequencing MRD assessment in ALL identifies patients at very low risk of relapse

Authors: Short, Nicholas J. ^*, Kantarjian, Hagop, Ravandi, Farhad, Konopleva, Marina, Jain, Nitin, Kanagal-Shamanna, Rashmi, Patel, Keyur P., Macaron, Walid, Kadia, Tapan M., Wang, Sa, Jorgensen, Jeffrey L., Khoury, Joseph D., Yilmaz, Musa, Kebriaei, Partow, Takahashi, Koichi, Garcia-Manero, Guillermo, Daver, Naval, Post, Sean M., Huang, Xuelin, Kornblau, Steven M., Pelletier, Sara, Flores, Wilmer, Matthews, Jairo, Garris, Rebecca, Jabbour, Elias ^*

Source: In Blood Advances 12 July 2022 6(13):4006-4014

TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia

Authors: Tashakori, Mehrnoosh, Kadia, Tapan, Loghavi, Sanam, Daver, Naval, Kanagal-Shamanna, Rashmi, Pierce, Sherry, Sui, Dawen, Wei, Peng, Khodakarami, Farnoosh, Tang, Zhenya, Routbort, Mark, Bivins, Carol A., Jabbour, Elias J., Medeiros, L. Jeffrey, Bhalla, Kapil, Kantarjian, Hagop M., Ravandi, Farhad, Khoury, Joseph D. ^*

Source: In Blood 7 July 2022 140(1):58-72

Differential characteristics of TP53 alterations in pure erythroid leukemia arising after exposure to cytotoxic therapy

Authors: Tashakori, Mehrnoosh, Wang, Wei, Kadia, Tapan M., Daver, Naval G., Montalban-Bravo, Guillermo, Loghavi, Sanam, Wang, Sa A., Medeiros, L. Jeffrey, Ravandi, Farhad, Khoury, Joseph D.

Source: In Leukemia Research July 2022 118