Circulating tumour DNA (ctDNA) in metastatic melanoma, a systematic review and meta-analysis

Authors: Gracie, Lara, Pan, Yi, Atenafu, Eshetu G., Ward, Douglas G., Teng, Mabel, Pallan, Lallit, Stevens, Neil M., Khoja, Leila

Source: In European Journal of Cancer November 2021 158:191-207

Correlation of Neutrophil to Lymphocyte Ratio and Absolute Neutrophil Count With Outcomes With PD-1 Axis Inhibitors in Patients With Advanced Non–Small-Cell Lung Cancer

Authors: Zer, Alona, Sung, Mike R., Walia, Preet, Khoja, Leila, Maganti, Manjula, Labbe, Catherine, Shepherd, Frances A., Bradbury, Penelope A., Feld, Ronald, Liu, Geoffrey, Iazzi, Melissa, Zawisza, Dianne, Nouriany, Nazanin, Leighl, Natasha B.

Source: In Clinical Lung Cancer September 2018 19(5):426-434

Characteristics and outcomes in patients with KRAS mutated lung adenocarcinomas: a retrospective data analysis

Authors: Zhang, Jingyao, Liu, Xuelian, O'Sullivan, Brendan, Taniere, Philippe, Baijal, Shobhit, Khoja, Leila, Pickles, Oliver

Source: Lung cancer. 178(S1):S34-S35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188395412.0x000001&indx=1&recIds=ETOCvdc_100188395412.0x000001

Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2

Authors: Nguyen, Linh T., Saibil, Samuel D., Sotov, Valentin, Le, Michael X., Khoja, Leila, Ghazarian, Danny, Bonilla, Luisa, Majeed, Habeeb, Hogg, David, Joshua, Anthony M., Crump, Michael, Franke, Norman, Spreafico, Anna, Hansen, Aaron, Al-Habeeb, Ayman, Leong, Wey, Easson, Alexandra, Reedijk, Michael, Goldstein, David P., McCready, David, Yasufuku, Kazuhiro, Waddell, Thomas, Cypel, Marcelo, Pierre, Andrew, Zhang, Bianzheng, Boross-Harmer, Sarah, Cipollone, Jane, Nelles, Megan, Scheid, Elizabeth, Fyrsta, Michael, Lo, Charlotte S., Nie, Jessica, Yam, Jennifer Y., Yen, Pei Hua, Gray, Diana, Motta, Vinicius, Elford, Alisha R., DeLuca, Stephanie, Wang, Lisa, Effendi, Stephanie, Ellenchery, Ragitha, Hirano, Naoto, Ohashi, Pamela S., Butler, Marcus O.

Source: Cancer immunology, immunotherapy. 68(5):773-785

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125514742.0x000001&indx=1&recIds=ETOCvdc_100125514742.0x000001

Prognostic factors for first-line therapy and overall survival of metastatic uveal melanoma: The Princess Margaret Cancer Centre experience

Authors: Nicholas, Mathew N., Khoja, Leila, Atenafu, Eshetu G., Hogg, David, Quirt, Ian, Butler, Marcus, Joshua, Anthony M.

Source: Melanoma research. 28(6):571-577

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100070760644.0x000001&indx=1&recIds=ETOCvdc_100070760644.0x000001

Malignant bowel obstruction in advanced ovarian cancer

Authors: Dean, Emma, Khoja, Leila, Clamp, Andrew, Jayson, Gordon C, Goonetilleke, Dilly, Conway, Alicia M, Hasan, Jurjees

Source: Future oncology. 13(6):513-521

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140746106.0x000001&indx=1&recIds=ETOCvdc_100140746106.0x000001

Significance of baseline FDG-PET/CT scan as a method of staging regional lymph nodes in patients with operable distal oesophageal or gastroesophageal junction adenocarcinoma

Authors: Papaxoinis, George, Weaver, Jamie M. J., Khoja, Leila, Patrao, Ana, Stamatopoulou, Sofia, Alchawaf, Alia, Owen-Holt, Vikki, Germetaki, Theodora, Kordatou, Zoe, Mansoor, Wasat

Source: Acta oncologica. 56(9):1224-1232

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100104509639.0x000001&indx=1&recIds=ETOCvdc_100104509639.0x000001

CDK4/6 inhibitors in metastatic breast cancer, a comparison of toxicity and efficacy across agents in a real-world dataset.

Authors: Buller, William, Pallan, Lalit, Chu, Teresa, Khoja, Leila

Source: Journal of Oncology Pharmacy Practice; Dec2023, Vol. 29 Issue 8, p1825-1835, 11p

Subject Terms: THERAPEUTIC use of antineoplastic agents, DRUG efficacy, CONFIDENCE intervals, METASTASIS, ANTINEOPLASTIC agents, ACQUISITION of data, RETROSPECTIVE studies, TERTIARY care, NEUTROPENIA, CYCLIN-dependent kinases, CANCER patients, COMPARATIVE studies, MEDICAL records, DESCRIPTIVE statistics, PROGRESSION-free survival, BREAST tumors, DRUG toxicity, CHEMICAL inhibitors, EVALUATION

Biomarker Utility of Circulating Tumor Cells in Metastatic Cutaneous Melanoma

Authors: Khoja, Leila, Lorigan, Paul ^*, Zhou, Cong, Lancashire, Matthew, Booth, Jessica, Cummings, Jeff, Califano, Raffaele, Clack, Glen, Hughes, Andrew, Dive, Caroline ^*

Source: In Journal of Investigative Dermatology June 2013 133(6):1582-1590

Guillain-Barré Syndrome following a series of novel therapies adapting the gold-standard in the era of immune priming

Authors: Maurice, Catherine, Khoja, Leila, Morgan, Erin, Mason, Warren P., Katzberg, Hans, Pereira, Austin M., Pereira, Amanda, Butler, Marcus

Source: JOURNAL OF NEUROIMMUNOLOGY. 346

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116712424.0x000001&indx=1&recIds=ETOCvdc_100116712424.0x000001

Multi-site clonality analysis uncovers pervasive heterogeneity across melanoma metastases

Authors: Rabbie, Roy, Ansari-Pour, Naser, Cast, Oliver, Lau, Doreen, Scott, Francis, Welsh, Sarah J., Parkinson, Christine, Khoja, Leila, Moore, Luiza, Tullett, Mark, Wong, Kim, Ferreira, Ingrid, Gómez, Julia M. Martínez, Levesque, Mitchell, Gallagher, Ferdia A., Jiménez-Sánchez, Alejandro, Riva, Laura, Miller, Martin L., Allinson, Kieren, Campbell, Peter J., Corrie, Pippa, Wedge, David C., Adams, David J.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174530673.0x000001&indx=1&recIds=ETOCvdc_100174530673.0x000001

Dabrafenib in the treatment of metastatic or unresectable melanoma

Authors: Khoja, Leila, Hogg, David

Source: Expert review of anticancer therapy. 15(3):265-276

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106675263.0x000001&indx=1&recIds=ETOCvdc_100106675263.0x000001

Extracellular vesicles from biological fluids as potential markers in castration resistant prostate cancer.

Authors: Choi, Wendy W. Y., Sánchez, Catherine, Li, Jiao Jiao, Dinarvand, Mojdeh, Adomat, Hans, Ghaffari, Mazyar, Khoja, Leila, Vafaee, Fatemeh, Joshua, Anthony M., Chi, Kim N., Guns, Emma S. Tomlinson, Hosseini-Beheshti, Elham

Source: Journal of Cancer Research & Clinical Oncology; Jul2023, Vol. 149 Issue 8, p4701-4717, 17p

Subject Terms: CASTRATION-resistant prostate cancer, EXTRACELLULAR vesicles, LIQUID chromatography-mass spectrometry, PROSTATE cancer patients, CELL anatomy

Management of immune-related hepatitis in patients being treated with checkpoint inhibitors for metastatic melanoma, a review and case series.

Authors: Tew, Alice¹ alice.tew@uhb.nhs.uk, Khoja, Leila^1,2, Pallan, Lalit¹, Steven, Neil^1,2

Source: Journal of Oncology Pharmacy Practice. Jul2023, Vol. 29 Issue 5, p1163-1171. 9p.

Subject Terms: *IMMUNE checkpoint inhibitors, *SCIENTIFIC observation, *MELANOMA, *METASTASIS, *HEPATITIS, *RETROSPECTIVE studies, *TERTIARY care, *HOSPITAL wards, *DESCRIPTIVE statistics, *DRUG side effects, *ONCOLOGY, *ALANINE aminotransferase

Evaluation of Hypertension and Proteinuria as Markers of Efficacy in Antiangiogenic Therapy for Metastatic Colorectal Cancer

Authors: Khoja, Leila, Kumaran, Gireesh, Zee, Ying Kiat, Murukesh, Nishanth, Swindell, Ric, Saunders, Mark P., Clamp, Andrew R., Valle, Juan W., Wilson, Greg, Jayson, Gordon C., Hasan, Jurjees

Source: Journal of clinical gastroenterology. 48(5):430-434

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100034188976.0x000001&indx=1&recIds=ETOCvdc_100034188976.0x000001

AR Signaling and the PI3K Pathway in Prostate Cancer.

Authors: Crumbaker, Megan^1,2 m.crumbaker@garvan.org.au, Khoja, Leila^3,4 lkhoja@yahoo.com, Joshua, Anthony M.^1,2,5 anthony.joshua@svha.org.au

Source: Cancers. Apr2017, Vol. 9 Issue 4, p34. 15p.

Subject Terms: *ANTIANDROGENS, *DRUG resistance in cancer cells, *PROSTATE tumors, *ANDROGEN receptors, *SIGNAL peptides

An open-label, multicenter phase I/IIa study evaluating the safety and clinical activity of clonal neoantigen reactive T cells in patients with advanced non-small cell lung cancer (CHIRON).

Authors: Jamal-Hanjani, Mariam, Greystoke, Alastair, Thistlethwaite, Fiona, Summers, Yvonne J., Allison, Jennifer, Cave, Judith, Orchard, Kim, Ottensmeier, Christian, Middleton, Gary, Khoja, Leila, Grant, Michael, Patel, Shreenal, Robertson, Jane, Peggs, Karl, Forster, Martin

Source: Journal of clinical oncology. 39(15 suppl):TPS9138-TPS9138

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173220559.0x000001&indx=1&recIds=ETOCvdc_100173220559.0x000001

80 - Characteristics and outcomes in patients with KRAS mutated lung adenocarcinomas: a retrospective data analysis

Authors: Zhang, Jingyao, Liu, Xuelian, O’Sullivan, Brendan, Taniere, Philippe, Baijal, Shobhit, Khoja, Leila, Pickles, Oliver

Source: In Lung Cancer April 2023 178 Supplement 1:S34-S35

Assessment of a prognostic model, PSA metrics and toxicities in metastatic castrate resistant prostate cancer using data from Project Data Sphere (PDS).

Authors: Pitcher, Bethany¹, Khoja, Leila², Hamilton, Robert J.³, Abdallah, Kald⁴, Pintilie, Melania¹, Joshua, Anthony M.^2,5 Anthony.joshua@svha.org.au

Source: PLoS ONE. 2/2/2017, Vol. 12 Issue 2, p1-12. 12p.

Subject Terms: *PROSTATE cancer prognosis, *PROSTATE cancer treatment, *DOCETAXEL, *DRUG toxicity, *RECEIVER operating characteristic curves, *LOGISTIC regression analysis

Adoptive cell therapy and modulation of the tumour microenvironment: new insights from ASCO 2016.

Authors: Khoja, Leila^1,2, Gyawali, Bishal³ bg.bishalgyawali@gmail.com

Source: Ecancermedicalscience. 2016, Vol. 10 Issue 651-673, p1-7. 7p.

Subject Terms: *CELLULAR therapy, *IMMUNOTHERAPY, *CANCER treatment, *T cells, *LYMPHOCYTES, *CANCER remission