Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma

Authors: Molodtsov, Aleksey K., Khatwani, Nikhil, Vella, Jennifer L., Lewis, Kathryn A., Zhao, Yanding, Han, Jichang, Sullivan, Delaney E., Searles, Tyler G., Preiss, Nicholas K., Shabaneh, Tamer B., Zhang, Peisheng, Hawkes, Aaron R., Malik, Brian T., Kolling, Fred W., IV, Usherwood, Edward J., Wong, Sandra L., Phillips, Joseph D., Shirai, Keisuke, Angeles, Christina V., Yan, Shaofeng, Curiel, Tyler J., Huang, Yina H., Cheng, Chao, Turk, Mary Jo

Source: In Immunity 14 September 2021 54(9):2117-2132

Memory CD8+ T cell responses to cancer

Authors: Han, Jichang, Khatwani, Nikhil, Searles, Tyler G., Turk, Mary Jo, Angeles, Christina V. ^*

Source: In Seminars in Immunology June 2020 49

mRNA structure regulates protein expression through changes in functional half-life

Authors: Mauger, David M., Cabral, B. Joseph, Presnyak, Vladimir, Su, Stephen V., Reid, David W., Goodman, Brooke, Link, Kristian, Khatwani, Nikhil, Reynders, John, Moore, Melissa J., McFadyen, Iain J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Nov . 116(48), 24075-24083.

Access URL: https://www.jstor.org/stable/26863080

Oncogenes Feed Treg Cells without Calling CD8s to the Table

Authors: Khatwani, Nikhil, Turk, Mary Jo

Source: Immunity. 53(1):13-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116286486.0x000001&indx=1&recIds=ETOCvdc_100116286486.0x000001

A novel approach for oxidation analysis of therapeutic proteins

Authors: Turyan, Iva, Khatwani, Nikhil, Sosic, Zoran, Jayawickreme, Shiranthi, Mandler, Daniel

Source: In Analytical Biochemistry 1 February 2016 494:108-113

T Cells and CDDO-Me Attenuate Immunosuppressive Activation of Human Melanoma-Conditioned Macrophages.

Authors: Torres, Gretel M., Yang, Heetaek, Park, Chanhyuk, Spezza, Paul A., Khatwani, Nikhil, Bhandari, Rajan, Liby, Karen T., Pioli, Patricia A.

Source: Frontiers in Immunology; 2/21/2022, Vol. 13, p1-11, 11p

Subject Terms: MELANOMA, T cells, MACROPHAGES, MACROPHAGE activation, IMMUNOSUPPRESSION, METHYL formate, T cell receptors

Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs.

Authors: Hewitt, Susannah L., Bai, Ailin, Bailey, Dyane, Ichikawa, Kana, Zielinski, John, Karp, Russell, Apte, Ameya, Arnold, Kristen, Zacharek, Sima J., Iliou, Maria S., Bhatt, Khushbu, Garnaas, Maija, Musenge, Faith, Davis, Ashley, Khatwani, Nikhil, Su, Stephen V., MacLean, Graham, Farlow, Samuel J., Burke, Kristine, Frederick, Joshua P.

Source: Science Translational Medicine; 1/30/2019, Vol. 11 Issue 477, pN.PAG-N.PAG, 1p

Subject Terms: ANTINEOPLASTIC agents, IMMUNOTHERAPY, CYTOKINES, IMMUNOSUPPRESSIVE agents, IMMUNOPHARMACOLOGY

Impact of mRNA chemistry and manufacturing process on innate immune activation.

Authors: Nelson, Jennifer^1,2, Sorensen, Elizabeth W.^1,3, Mintri, Shrutika^1,4, Rabideau, Amy E.¹, Wei Zheng¹, Besin, Gilles^1,5, Khatwani, Nikhil^1,6, Su, Stephen V.^1,7, Miracco, Edward J.¹, Issa, William J.¹, Hoge, Stephen¹, Stanton, Matthew G.¹, Joyal, John L.^1,8 john.joyal@modernatx.com

Source: Science Advances. 6/24/2020, Vol. 6 Issue 26, p1-13. 13p.

Subject Terms: *INTERFERON receptors, *MESSENGER RNA, *MANUFACTURING processes, *MYELOID differentiation factor 88, *CHEMISTRY, *CYTOTOXIC T cells, *INFLUENZA A virus, H7N9 subtype