Improving outcomes of hematopoietic stem cell transplant for leukemia in children and young adults in resource-limited setting

Authors: Nirmal, Garima ^a, Paul, Subhashish ^a, Chadha, Vaibhav ^a, Das, Shreyasi ^a, Chaudhary, Mohit ^b, Joseph, Manju ^a, Sharma, Bharti ^a, Yadav, Himshikha ^a, Swathymon, K.K. ^a, Kamol, Iskandarov ^c, Kharya, Gaurav ^{a, ⁎}

Source: In Pediatric Hematology Oncology Journal June 2024 9(2):105-113

Outcomes of COVID-19 in children with cancer – Report from the Indian Pediatric Oncology Group (InPOG) COVID-19 registry in India

Authors: Raj, Revathi, Uppuluri, Ramya, Parambil, Badira, Dhariwal, Nidhi, Totadri, Sidharth, Mathew, Leni Grace, Radhakrishnan, Venkatraman, Charan, Abhishek, Yadav, Satya Prakash, Mahajan, Amita, Mudaliar, Sangeeta, Sharma, Ratna, Manglani, Mamta, Kharya, Gaurav, Verma, Nishant, Arora, Ramandeep, Ghara, Niharendu, KS, Reghu, Radhakrishnan, Nita, Iyer, Nisha, Mehta, Priti, Singh, Amitabh, Patel, Shivani, John, Joseph, Bhat, Sunil, Badiger, Shobha, Siddaiahgari, Sirisharani, Kakkar, Shruti, Scott, Julius, Jayaraman, Dhaarani, Srinivasan, Arathi, Krishnan, Yamini, Sonamani, Ngangbam, Misra, Ruchira, Bafna, Vibha, Seth, Rachna, Kutty, Purvi Kadakia, Kanakia, Swati, Rao, Vasudha, Prakash, Anand, Bharadwaj, Vandana, Chinnasamy, Girish

Source: In Pediatric Hematology Oncology Journal June 2022 7(2):34-37

A Comparative Analysis of Low Dose Grafalon^® Versus Thymoglobuline^® as Serotherapy in Hematopoietic Stem Cell Transplant in Pediatric and Young Adult Population.

Authors: Nirmal, Garima¹ (AUTHOR), Kharya, Gaurav¹ (AUTHOR) gaurav.kharya@gmail.com, Shankar, Ravi¹ (AUTHOR), Singh, Saksham¹ (AUTHOR), Paul, Subhasish¹ (AUTHOR), Choudhary, Mohit² (AUTHOR), Chadha, Vaibhav¹ (AUTHOR), Iskandarov, Kamol³ (AUTHOR), Begali, Sayitov³ (AUTHOR), Bakane, Atish¹ (AUTHOR), Chatterjee, Goutomi¹ (AUTHOR)

Source: Pediatric Hematology & Oncology. Nov2024, Vol. 41 Issue 8, p557-571. 15p.

Subject Terms: *HEMATOPOIETIC stem cell transplantation, *STEM cell transplantation, *HEMATOPOIETIC stem cells, *SEROTHERAPY, *YOUNG adults

Comparison of Amicus and COBE Spectra for allogenic peripheral blood stem cell harvest: Study from tertiary care centre in India

Authors: Setia, Rasika Dhawan, Arora, Satyam, Handoo, Anil, Dadu, Tina, Choudhary, Dharma, Sharma, Sajeev Kumar, Kharya, Gaurav, Khandelwal, Vipin, Sachdeva, Prerna, Doval, Divya, Bakliwal, Anamika, Kapoor, Meenu, Bajaj, Shalu, Bachchas, Virendra, Singh, Praveen

Source: In Transfusion and Apheresis Science June 2017 56(3):439-444

HLA‐haploidentical stem cell transplantation in children with inherited bone marrow failure syndromes: A retrospective analysis on behalf of EBMT severe aplastic Anemia and pediatric diseases working parties.

Authors: Giardino, Stefano, Eikema, Dirk‐Jan, Piepenbroek, Brian, Algeri, Mattia, Ayas, Mouhab, Faraci, Maura, Tbakhi, Abdelghani, Zecca, Marco, Essa, Mohammed, Neven, Bénédicte, Bertrand, Yves, Kharya, Gaurav, Bykova, Tatiana, Lawson, Sarah, Petrini, Mario, Mohseny, Alexander, Rialland, Fanny, James, Beki, Colita, Anca, Fahd, Mony

Source: American Journal of Hematology; Jun2024, Vol. 99 Issue 6, p1066-1076, 11p

An International Survey of Allogeneic Hematopoietic Cell Transplantation for X-Linked Agammaglobulinemia.

Authors: Nishimura, Akira, Uppuluri, Ramya, Raj, Revathi, Swaminathan, Venkateswaran Vellaichamy, Cheng, Yifei, Abu-Arja, Rolla F., Fu, Bin, Laberko, Alexandra, Albert, Michael H., Hauck, Fabian, Bucciol, Giorgia, Bigley, Venetia, Elcombe, Suzanne, Kharya, Gaurav, Pronk, Cornelis Jan H, Wehr, Claudia, Neven, Bénédicte, Warnatz, Klaus, Meyts, Isabelle, Morio, Tomohiro

Source: Journal of Clinical Immunology; Nov2023, Vol. 43 Issue 8, p1827-1839, 13p

Subject Terms: HEMATOPOIETIC stem cell transplantation, AGAMMAGLOBULINEMIA, BRUTON tyrosine kinase

HLA-Haploidentical Stem Cell Transplantation in Children with Inherited Bone Marrow Failure Syndromes: A Retrospective Analysis on Behalf of EBMT Severe Aplastic Anemia Working Party

Authors: Giardino, Stefano ^*, Eikema, Dirk-Jan ^*, Piepenbroek, Brian ^*, Algeri, Mattia ^*, Ayas, Mouhab, Faraci, Maura ^*, Tbakhi, Abdelghani ^*, Zecca, Marco ^*, Essa, Mohammed ^*, Neven, Bénédicte ^*, Bertrand, Yves ^*, Kharya, Gaurav ^*, Bykova, Tatiana A ^*, Lawson, Sarah ^*, Petrini, Mario, Mohseny, Alexander ^*, Rialland, Fanny ^*, James, Beki ^*, Colita, Anca ^*, Fahd, Mony ^*, Cesaro, Simone ^*, Schulz, Ansgar ^*, Dufour, Carlo, Risitano, Antonio, Peffault de Latour, Régis ^*

Source: In Blood 15 November 2022 140 Supplement 1:5813-5815

Outcome of allogeneic stem cell transplant for Fanconi anemia in India.

Authors: Yadav, Satya Prakash, Raj, Revathi, Uppuluri, Ramya, Choudhary, Dharma, Doval, Divya, Dua, Vikas, Bhat, Sunil, Kharya, Gaurav, Patil, Rajesh, Bansal, Shweta, M, Deendayalan, Mehdi, Intezar, Mathews, Vikram, Abraham, Aby, George, Biju

Source: Pediatric Hematology & Oncology; 2024, Vol. 41 Issue 2, p169-171, 3p

Subject Terms: FANCONI'S anemia, STEM cell transplantation, HEMATOPOIETIC stem cell transplantation, BONE marrow transplantation

Sirolimus-induced Hypertriglyceridemia Leads to Acute Pancreatitis and Diabetic Ketoacidosis Post Stem Cell Transplant for Sickle Cell Disease.

Authors: Paul, Subhasish, Nirmal, Garima, Chadha, Vaibhav, Sharma, Rahul, Kochar, I. P. S., Jerath, Namith, Vohra, Rohit, Kharya, Gaurav

Source: Journal of Pediatric Hematology/Oncology; Jan2024, Vol. 46 Issue 1, pe91-e93, 3p

Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells.

Authors: Sagar, Shakti, Faizan, Md Imam, Chaudhary, Nisha, Singh, Vandana, Singh, Praveen, Gheware, Atish, Sharma, Khushboo, Azmi, Iqbal, Singh, Vijay Pal, Kharya, Gaurav, Mabalirajan, Ulaganathan, Agrawal, Anurag, Ahmad, Tanveer, Sinha Roy, Soumya

Source: Cell Death & Disease; May2023, Vol. 14 Issue 5, p1-19, 19p

Dry Gangrene of Feet in an Apparently Well Neonate.

Authors: Ankur, Kumar, Prasad, Aparna, Kharya, Gaurav, Chetry, Sanjeev

Source: NeoReviews; Mar2023, Vol. 24 Issue 3, pe184-e187, 4p

Incidence, risk factors and outcomes of graft failure post stem cell transplant: Experience from a single tertiary care centre

Authors: Chadha, Vaibhav, Nirmal, Garima, Gupta, Nikhil, Srivastava, Nidhi, Kharya, Gaurav

Source: In Pediatric Hematology Oncology Journal 2024 9(4) Supplement:S83-S84

Post-transplant cyclophosphamide as GVHD prophylaxis for peripheral blood stem cell in HLA-related/ unrelated donor HSCT - A new paradigm shift

Authors: Gupta, Nikhil, Nirmal, Garima, Chadha, Vaibhav, kharya, Gaurav

Source: In Pediatric Hematology Oncology Journal 2024 9(4) Supplement:S82-S82

Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity

Authors: Akhtar, Areej, Shakir, Md, Ansari, Mohammad Sufyan, Divya, Faizan, Md Imam, Chauhan, Varnit, Singh, Aashi, Alam, Ruquaiya, Azmi, Iqbal, Sharma, Sheetal, Pracha, Mehak, Uddin, Insha Mohi, Bashir, Uzma, Shahni, Syeda Najidah, Chaudhuri, Rituparna, Albogami, Sarah, Ganguly, Rik, Sagar, Shakti, Singh, Vijay Pal, Kharya, Gaurav, Srivastava, Amit Kumar, Mabalirajan, Ulaganathan, Roy, Soumya Sinha, Rahman, Irfan, Ahmad, Tanveer

Source: Cell Reports Medicine; March 2025, Vol. 6 Issue: 3

Impact of Conditioning Regimen and Graft-versus-Host Disease Prophylaxis on The Outcome of Haploidentical Peripheral Blood Stem Cell Transplantation for High-Risk Severe Aplastic Anemia in Children and Young Adults: A Report from the Pediatric Severe Aplastic Anemia Consortium of India

Authors: Kharya, Gaurav, Jaiswal, Sarita R., Bhat, Sunil, Raj, Revathi, Yadav, Satya P., Dua, Vikas, Sen, Santanu, Bakane, Atish, Badiger, Shobha, Uppuluri, Ramya, Rastogi, Neha, Sachdev, Mansi, Sharma, Bharti, Saifullah, Ashraf, Chakrabarti, Suparno

Source: Transplantation and Cellular Therapy; March 2023, Vol. 29 Issue: 3 p199.e1-199.e10, 17920p

NSP4 and ORF9b of SARS-CoV-2 Induce Pro-Inflammatory Mitochondrial DNA Release in Inner Membrane-Derived Vesicles.

Authors: Faizan, Md Imam, Chaudhuri, Rituparna, Sagar, Shakti, Albogami, Sarah, Chaudhary, Nisha, Azmi, Iqbal, Akhtar, Areej, Ali, Syed Mansoor, Kumar, Rohit, Iqbal, Jawed, Joshi, Mohan C., Kharya, Gaurav, Seth, Pankaj, Roy, Soumya Sinha, Ahmad, Tanveer

Source: Cells (2073-4409); Oct2022, Vol. 11 Issue 19, p2969, 36p

Subject Terms: MITOCHONDRIAL DNA, CELL death, MITOCHONDRIAL membranes, HUMAN stem cells, SARS-CoV-2, MESENCHYMAL stem cells, MYELOID cells, COVID-19

A Simple, Cost-Effective, and Extraction-Free Molecular Diagnostic Test for Sickle Cell Disease Using a Noninvasive Buccal Swab Specimen for a Limited-Resource Setting.

Authors: Thakur, Priya, Gupta, Pragya, Bhargava, Nupur, Soni, Rajat, Varma Gottumukkala, Narendra, Goswami, Sangam Giri, Kharya, Gaurav, Saravanakumar, Vinodh, Gunda, Padma, Jain, Suman, Dass, Jasmita, Aggarwal, Mukul, Ramalingam, Sivaprakash

Source: Diagnostics (2075-4418); Jul2022, Vol. 12 Issue 7, pN.PAG-N.PAG, 14p

Subject Terms: SICKLE cell anemia, DIAGNOSIS methods, BONE marrow transplantation, GENE amplification, MOLECULAR diagnosis, GENETIC disorders

Diagnosis and Management of Acquired Aplastic Anemia: Consensus Statement of Indian Academy of Pediatrics.

Authors: Danewa, Arun, Kalra, Manas, Sachdeva, Anupam, Sachdeva, Pallavi, Bansal, Deepak, Bhat, Sunil, Sachdeva, Divij, Rani, Sirisha, Yadav, Satya P., Katewa, Satyendra, Kumar, Archana, Muniratnam, Deendayalan, Agarwal, Bharat R., Seth, Tulika, Mahajan, Amita, Dua, Vikas, Kharya, Gaurav, Misra, Ruchira, Desai, Dhwanee, Gunasekaran, Vinod

Source: Indian Pediatrics; Jun2022, Vol. 59 Issue 6, p467-475, 9p

Subject Terms: APLASTIC anemia, HEMATOPOIETIC stem cell transplantation, GRAFT versus host disease, DIAGNOSIS, PAROXYSMAL hemoglobinuria, IMMUNOSUPPRESSIVE agents

Geographic Terms: HYDERABAD (India), INDIA

Thiotepa-based reduced toxicity conditioning in combination with post-transplant cyclophosphamide and mTOR inhibitor for heavily transfused acquired severe aplastic anemia in children and young adults: encouraging outcomes of a pilot study

Authors: Kharya, Gaurav, Sapkota, Sudhir, Teotia, Neeraj, Chaudhary, Mohit, Swathymon, K. K., Chodan, Pema, Peters, Sherin, Anthony, Anju, Sharma, Bharti, Yadav, Himshikha, Bakane, Atish, Joseph, Manju

Source: Bone Marrow Transplantation; February 2023, Vol. 58 Issue: 2 p233-236, 4p

553 - Thiotepa Based Reduced Toxicity Conditioning for Heavily Transfused Acquired Severe Aplastic Anemia in Children and Young Adults: Exceptional Outcomes of a Pilot Study

Authors: Kharya, Gaurav, Teotia, Neeraj, Sapkota, Sudhir, Chaudhary, Mohit, Joseph, Manju, Sharma, Bharti, Yadav, Himshikha, Bakane, Atish

Source: In Transplantation and Cellular Therapy March 2022 28(3) Supplement:S430-S430