Morphine and hydromorphone pharmacokinetics in human volunteers: population-based modelling of interindividual and opioid-related variability

Authors: Meissner, Konrad ^{1, 2, †}, Olofsen, Erik ^{2, †}, Dahan, Albert ², Kharasch, Evan D. ^{3, 4, ⁎}

Source: In British Journal of Anaesthesia February 2025 134(2):358-367

Intraoperative methadone administration for total mastectomy: A single center retrospective study

Authors: Cata, Juan P., Zaidi, Yusuf, Guerra-Londono, Juan Jose, Kharasch, Evan D., Piotrowski, Matthew, Kee, Spencer, Cortes-Mejia, Nicolas A., Gloria-Escobar, Jose Miguel, Thall, Peter F., Lin, Ruitao

Source: In Journal of Clinical Anesthesia November 2024 98

Methods and systems for preparing and preserving a biological sample

Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion

Authors: Kharasch, Evan D. ^*, Lenze, Eric J.

Source: In Drug Metabolism and Disposition May 2024 52(5):455-466

Natural Products Inhibition of Cytochrome P450 2B6 Activity and Methadone Metabolism

Authors: Wang, Pan-Fen ¹, Yang, Yanming ¹, Patel, Vishal, Neiner, Alicia, Kharasch, Evan D. ^*

Source: In Drug Metabolism and Disposition March 2024 52(3):252-265

An investigation of the potential clinical utility of critical slowing down as an early warning sign for recurrence of depression

Authors: Tonge, Natasha A., Miller, J. Philip, Kharasch, Evan D., Lenze, Eric J., Rodebaugh, Thomas L.

Source: In Journal of Behavior Therapy and Experimental Psychiatry March 2024 82

Scholarly Debate About Drug Efficacy in Scientific Journals Is “Protected Speech,” Not Libel

Authors: Kharasch, Evan D., Klaas, Paul B., Lanier, William L.

Source: In Mayo Clinic Proceedings February 2024 99(2):198-202

Opioid sensitivity in treated and untreated obstructive sleep apnoea: a prospective cohort study

Authors: Montana, Michael C., McLeland, Michael, Fisher, Marilee, Juriga, Lindsay, Ercole, Patrick M., Kharasch, Evan D.

Source: In British Journal of Anaesthesia January 2024 132(1):145-153

Morphine and Hydromorphone Effects, Side Effects, and Variability: A Crossover Study in Human Volunteers

Authors: Meissner, Konrad, Dahan, Albert, Olofsen, Erik, Göpfert, Christine, Blood, Jane, Wieditz, Johannes, Kharasch, Evan D.

Source: Anesthesiology. 139(1):16-34

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194000271.0x000001&indx=1&recIds=ETOCvdc_100194000271.0x000001

Modeling adult COX‐2 cerebrospinal fluid pharmacokinetics to inform pediatric investigation

Authors: Hannam, Jacqueline A., Murto, Kimmo T., Anderson, Brian J., Dembo, Gregory, Kharasch, Evan D.

Source: Paediatric anaesthesia. 33(4):291-302

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177017858.0x000001&indx=1&recIds=ETOCvdc_100177017858.0x000001

Anesthesiology 2023: Ch-ch-ch-ch-changes

Authors: Kharasch, Evan D.

Source: Anesthesiology. 138(1):1-3

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193999271.0x000001&indx=1&recIds=ETOCvdc_100193999271.0x000001

Journal-related Activities and Other Special Activities at the 2022 American Society of Anesthesiologists Meeting

Authors: Avram, Michael J., Culley, Deborah J., Davidson, Andrew, Kharasch, Evan D., Kheterpal, Sachin, London, Martin J., Melo, Marcos F. Vidal

Source: Anesthesiology. 137(4):387-395

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193998123.0x000001&indx=1&recIds=ETOCvdc_100193998123.0x000001

Opioids and Public Health: The Prescription Opioid Ecosystem and Need for Improved Management

Authors: Kharasch, Evan D., Clark, J. David, Adams, Jerome M.

Source: Anesthesiology. 136(1):10-30

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193993547.0x000001&indx=1&recIds=ETOCvdc_100193993547.0x000001

Methadone pharmacogenetics in vitro and in vivo: Metabolism by CYP2B6 polymorphic variants and genetic variability in paediatric disposition

Authors: Wang, Pan‐Fen, Sharma, Anshuman, Montana, Michael, Neiner, Alicia, Juriga, Lindsay, Reddy, Kavya Narayana, Tallchief, Dani, Blood, Jane, Kharasch, Evan D.

Source: British journal of clinical pharmacology. 88(11):4881-4893

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165259103.0x000001&indx=1&recIds=ETOCvdc_100165259103.0x000001

Methadone metabolism and cytochrome P450 polymorphisms: a systematic review and meta-analysis.

Authors: Eum, Seenae, Vernacchia, Nicholas P., Doughty, Nia, Mehrzad, Sahar, Talal, Andrew H., Chalabianloo, Fatemeh, Kharasch, Evan D.

Source: Expert Opinion on Drug Metabolism & Toxicology; Mar2025, Vol. 21 Issue 3, p289-304, 16p

Plasma and cerebrospinal fluid pharmacokinetics of ondansetron in humans

Authors: Chiang, Manting D., Frey, Karen, Lee, Chris, Kharasch, Evan D., Tallchief, Dani, Sawyer, Christopher, Blood, Jane, Back, Hyunmoon, Kagan, Leonid, Haroutounian, Simon

Source: British journal of clinical pharmacology. 87(2):516-526

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134513814.0x000001&indx=1&recIds=ETOCvdc_100134513814.0x000001

Anesthesiology: Reflecting and Leading

Authors: Kharasch, Evan D.

Source: Anesthesiology. 135(4):551-554

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194182914.0x000001&indx=1&recIds=ETOCvdc_100194182914.0x000001

Journal-related Activities and Other Special Activities at the 2021 American Society of Anesthesiologists Meeting

Authors: Avram, Michael J., Culley, Deborah J., Kharasch, Evan D., Levy, Jerrold H., London, Martin J.

Source: Anesthesiology. 135(4):576-584

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194182967.0x000001&indx=1&recIds=ETOCvdc_100194182967.0x000001

Authorship and Publication Matters: Credit and Credibility

Authors: Kharasch, Evan D., Avram, Michael J., Bateman, Brian T., Clark, J. David, Culley, Deborah J., Davidson, Andrew J., Houle, Timothy T., Jiang, Yandong, Levy, Jerrold H., London, Martin J., Sleigh, Jamie W., Vutskits, Laszlo

Source: Anesthesiology. 135(1):1-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194182161.0x000001&indx=1&recIds=ETOCvdc_100194182161.0x000001

Methadone and Ketamine: Boosting Benefits and Still More to Learn

Authors: Kharasch, Evan D., Clark, J. David

Source: Anesthesiology. 134(5):676-679

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194181479.0x000001&indx=1&recIds=ETOCvdc_100194181479.0x000001