Molecular Determinants of Mitochondrial Shape and Function and Their Role in Glaucoma

Authors: Khalimonchuk, Oleh, Becker, Donald F.

Source: Antioxidants & redox signaling. 38(13/15):896-919

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181073120.0x000001&indx=1&recIds=ETOCvdc_100181073120.0x000001

Evidence that the catalytic mechanism of heme a synthase involves the formation of a carbocation stabilized by a conserved glutamate

Authors: Rivett, Elise D., Addis, Hannah G., Dietz, Jonathan V., Carroll-Deaton, Jayda A., Gupta, Shipra, Foreman, Koji L., Dang, Minh Anh, Fox, Jennifer L., Khalimonchuk, Oleh, Hegg, Eric L.

Source: In Archives of Biochemistry and Biophysics August 2023 744

Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase

Authors: Dietz, Jonathan V., Willoughby, Mathilda M., Piel, Robert B., III, Ross, Teresa A., Bohovych, Iryna, Addis, Hannah G., Fox, Jennifer L., Lanzilotta, William N., Dailey, Harry A., Wohlschlegel, James A., Reddi, Amit R., Medlock, Amy E., Khalimonchuk, Oleh

Source: In Redox Biology October 2021 46

Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity

Authors: Cheng, Xiao, Shihabudeen Haider Ali, Mohamed Sham, Moran, Matthew, Viana, Martonio Ponte, Schlichte, Sarah L., Zimmerman, Matthew C., Khalimonchuk, Oleh, Feinberg, Mark W., Sun, Xinghui

Source: In Redox Biology April 2021 40

The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism

Authors: Acoba, Michelle Grace, Alpergin, Ebru S. Selen, Renuse, Santosh, Fernández-del-Río, Lucía, Lu, Ya-Wen, Khalimonchuk, Oleh, Clarke, Catherine F., Pandey, Akhilesh, Wolfgang, Michael J., Claypool, Steven M.

Source: In Cell Reports 16 March 2021 34(11)

Protease OMA1 modulates mitochondrial bioenergetics and ultrastructure through dynamic association with MICOS complex

Authors: Viana, Martonio Ponte, Levytskyy, Roman M., Anand, Ruchika, Reichert, Andreas S., Khalimonchuk, Oleh

Source: In iScience 19 February 2021 24(2)

Proteolytic regulation of mitochondrial dynamics

Authors: Dietz, Jonathan V., Bohovych, Iryna, Viana, Martonio Ponte, Khalimonchuk, Oleh

Source: In Mitochondrion November 2019 49:289-304

Vitamin B5 metabolism is essential for vacuolar and mitochondrial functions and drug detoxification in fungi.

Authors: Choi, Jae-Yeon, Gihaz, Shalev, Munshi, Muhammad, Singh, Pallavi, Vydyam, Pratap, Hamel, Patrice, Adams, Emily M., Sun, Xinghui, Khalimonchuk, Oleh, Fuller, Kevin, Ben Mamoun, Choukri

Source: Communications Biology; 7/23/2024, Vol. 7 Issue 1, p1-16, 16p

Subject Terms: PANTOTHENIC acid, DRUG synergism, GENETIC regulation, METABOLISM, XENOBIOTICS, ANTIFUNGAL agents, FUNGAL cell walls

Intraperitoneal nanotherapy for metastatic ovarian cancer based on siRNA-mediated suppression of DJ-1 protein combined with a low dose of cisplatin

Authors: Schumann, Canan, Chan, Stephanie, Millar, Jess A., Bortnyak, Yuliya, Carey, Katherine, Fedchyk, Alex, Wong, Leon, Korzun, Tetiana, Moses, Abraham S., Lorenz, Anna, Shea, Delany, Taratula, Olena, Khalimonchuk, Oleh, Taratula, Oleh

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine June 2018 14(4):1395-1405

Redox Regulation of the Mitochondrial Quality Control Protease Oma1

Authors: Bohovych, Iryna, Dietz, Jonathan V., Swenson, Samantha, Zahayko, Nataliya, Khalimonchuk, Oleh

Source: Antioxidants & redox signaling. 31(6):429-443

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084586629.0x000001&indx=1&recIds=ETOCvdc_100084586629.0x000001

Depletion of mitochondrial protease OMA1 alters proliferative properties and promotes metastatic growth of breast cancer cells

Authors: Daverey, Amita, Levytskyy, Roman, Stanke, Kimberly, Viana, Martonio, Swenson, Samantha, Hayward, Stephen, Narasimhan, Madhusudhanan, Khalimonchuk, Oleh, Kidambi, Srivatsan

Source: Scientific reports. 9(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190851479.0x000001&indx=1&recIds=ETOCvdc_100190851479.0x000001

The Assembly Factor Pet117 Couples Heme a Synthase Activity to Cytochrome Oxidase Assembly

Authors: Taylor, Nicholas G., Swenson, Samantha, Harris, Nicholas J., Germany, Edward M., Fox, Jennifer L., Khalimonchuk, Oleh

Source: In Journal of Biological Chemistry 3 February 2017 292(5):1815-1825

Abstract 1569 Elucidating the role of disease-associated mitochondrial factor Mdm38/LETM1

Authors: Menezes da Silva, Gabriella, Bohovych, Iryna, Mahdi, Rabab, Khalimonchuk, Oleh

Source: In Journal of Biological Chemistry March 2024 300(3) Supplement

Chapter Three - Mitochondrial metallopeptidase OMA1 in cancer

Authors: Purohit, Gunjan, Ghosh, Polash, Khalimonchuk, Oleh

Source: In Advances in Cancer Research 2024 162:75-97

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission

Authors: Tsushima, Kensuke, Bugger, Heiko, Wende, Adam R., Soto, Jamie, Jenson, Gregory A., Tor, Austin R., McGlauflin, Rose, Kenny, Helena C., Zhang, Yuan, Souvenir, Rhonda, Hu, Xiao X., Sloan, Crystal L., Pereira, Renata O., Lira, Vitor A., Spitzer, Kenneth W., Sharp, Terry L., Shoghi, Kooresh I., Sparagna, Genevieve C., Rog-Zielinska, Eva A., Kohl, Peter, Khalimonchuk, Oleh, Schaffer, Jean E., Abel, E. Dale

Source: Circulation research. 122(1):58-73

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100066172991.0x000001&indx=1&recIds=ETOCvdc_100066172991.0x000001

Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes

Authors: Swenson, Samantha, Cannon, Andrew, Harris, Nicholas J., Taylor, Nicholas G., Fox, Jennifer L., Khalimonchuk, Oleh

Source: In Journal of Biological Chemistry 6 May 2016 291(19):10411-10425

ROS-induced nanotherapeutic approach for ovarian cancer treatment based on the combinatorial effect of photodynamic therapy and DJ-1 gene suppression

Authors: Schumann, Canan, Taratula, Olena, Khalimonchuk, Oleh, Palmer, Amy L., Cronk, Lauren M., Jones, Carson V., Escalante, Cesar A., Taratula, Oleh

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine November 2015 11(8):1961-1970

Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways

Authors: Anandhan, Annadurai, Rodriguez-Rocha, Humberto, Bohovych, Iryna, Griggs, Amy M., Zavala-Flores, Laura, Reyes-Reyes, Elsa M., Seravalli, Javier, Stanciu, Lia A., Lee, Jaekwon, Rochet, Jean-Christophe, Khalimonchuk, Oleh, Franco, Rodrigo

Source: In Neurobiology of Disease September 2015 81:76-92

Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking

Alternate Title: Hyaluronidase and Vesicle Trafficking (English)

Authors: McAtee, Caitlin O., Berkebile, Abigail R., Elowsky, Christian G., Fangman, Teresa, Barycki, Joseph J., Wahl, James K., III, Khalimonchuk, Oleh, Naslavsky, Naava, Caplan, Steve ^**, Simpson, Melanie A. ^**

Source: In Journal of Biological Chemistry 22 May 2015 290(21):13144-13156

Metalloproteases of the Inner Mitochondrial Membrane

Authors: Levytskyy, Roman M., Bohovych, Iryna, Khalimonchuk, Oleh

Source: Biochemistry. 56(36):4737-4746

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612937291&indx=1&recIds=ETOCRN612937291