Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk

Authors: Kevin Qin, Michael Yu, Jiaming Fan, Hongwei Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Connie Chen, Yonghui Wang, Annie Wang, Zander Schwartz, Jeffrey Hong, Lily Song, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin H. Ho, Jason Strelzow, Russell R. Reid, Tong-Chuan He, Lewis L. Shi

Source: Genes and Diseases, Vol 11, Iss 1, Pp 103-134 (2024)

Subject Terms: β-catenin, Canonical Wnt, Noncanonical Wnt, Signal transduction, Signaling crosstalk, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223000557; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/e9c5d2e8d60a4f7bab671fa685bf5817

The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities

Authors: Michael Yu, Kevin Qin, Jiaming Fan, Guozhi Zhao, Piao Zhao, Wei Zeng, Connie Chen, Annie Wang, Yonghui Wang, Jiamin Zhong, Yi Zhu, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin Ho, Michael J. Lee, Jason Strelzow, Russell R. Reid, Tong-Chuan He

Source: Genes and Diseases, Vol 11, Iss 3, Pp 101026- (2024)

Subject Terms: β-Catenin, Cancer, Canonical Wnt, Disease, Non-canonical Wnt, Stem cells, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223002945; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/8392f7d2b6e1410eb1a27610ae0740c2

Modeling lung diseases using reversibly immortalized mouse pulmonary alveolar type 2 cells (imPAC2)

Authors: Linghuan Zhang, Wenping Luo, Jiang Liu, Maozhu Xu, Qi Peng, Wenjing Zou, Jingyi You, Yi Shu, Piao Zhao, William Wagstaff, Guozhi Zhao, Kevin Qin, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Yang Bi, Tianyu Zhao, Tong-Chuan He, Zhou Fu

Source: Cell & Bioscience, Vol 12, Iss 1, Pp 1-18 (2022)

Subject Terms: Alveolar type 2 cells (AT2), Pulmonary alveolar epithelium, Immortalization, Alveolar organoids, Lung progenitors, Pulmonary fibrosis, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/eb81371f8db944edb708742645fa38e7

A cell-penetrating PHLPP peptide improves cardiac arrest survival in murine and swine models

Authors: Jing Li, Xiangdong Zhu, Matt T. Oberdier, Chunpei Lee, Shaoxia Lin, Sarah J. Fink, Cody N. Justice, Kevin Qin, Andrew W. Begeman, Frederick C. Damen, Hajwa Kim, Jiwang Chen, Kejia Cai, Henry R. Halperin, Terry L. Vanden Hoek

Source: The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)

Subject Terms: Therapeutics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/21e1ed80f0e04c6797c226e941845f6f

Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer

Authors: Feifei Pu, Fengxia Chen, Zhicai Zhang, Deyao Shi, Binlong Zhong, Xiao Lv, Andrew Blake Tucker, Jiaming Fan, Alexander J. Li, Kevin Qin, Daniel Hu, Connie Chen, Hao Wang, Fang He, Na Ni, Linjuan Huang, Qing Liu, William Wagstaff, Hue H. Luu, Rex C. Haydon, Le Shen, Tong-Chuan He, Jianxiang Liu, Zengwu Shao

Source: Genes and Diseases, Vol 9, Iss 2, Pp 347-357 (2022)

Subject Terms: Cancer, Cancer therapy, Clinical application, Ferroptosis, Lipid peroxidation, Pathogenesis, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304220301562; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/7ada6379f31f407297d60e372884c349

Notch signaling: Its essential roles in bone and craniofacial development

Authors: Mikhail Pakvasa, Pranav Haravu, Michael Boachie-Mensah, Alonzo Jones, Elam Coalson, Junyi Liao, Zongyue Zeng, Di Wu, Kevin Qin, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Fang He, Yukun Mao, Yongtao Zhang, Changchun Niu, Meng Wu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Michael J. Lee, Jennifer Moriatis Wolf, Aravind Athiviraham, Sherwin S. Ho, Tong-Chuan He, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, Russell R. Reid

Source: Genes and Diseases, Vol 8, Iss 1, Pp 8-24 (2021)

Subject Terms: Alagille syndrome, Bone, Craniofacial development, Craniosynostosis, Notch, Oncogenesis, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304220300581; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/a4d47992f466402eb32b414c1d24bc69

FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells

Authors: Fang He, Na Ni, Zongyue Zeng, Di Wu, Yixiao Feng, Alexander J. Li, Benjamin Luu, Alissa F. Li, Kevin Qin, Eric Wang, Xi Wang, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Yukun Mao, Mikhail Pakvasa, William Wagstaff, Yongtao Zhang, Changchun Niu, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Xia Zhao, Kai Fu, Russell R. Reid, Jennifer Moriatis Wolf, Michael J. Lee, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, Hua Gan, Tong-Chuan He, Jiaming Fan

Source: Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 885-899 (2020)

Subject Terms: RNA interference, RNAi, double-stranded small interfering RNA, siRNA, BMP9/Smad signaling, mesenchymal stem cells, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S216225312030319X; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/6d0374a049b84e5ab294d9468447091c

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