Remodeling of the gastric environment in Helicobacter pylori-induced atrophic gastritis

Authors: Jennifer H. B. Shuman, Aung Soe Lin, Mandy D. Westland, Kaeli N. Bryant, M. Blanca Piazuelo, Michelle L. Reyzer, Audra M. Judd, W. Hayes McDonald, Mark S. McClain, Kevin L. Schey, Holly M. S. Algood, Timothy L. Cover

Source: mSystems, Vol 9, Iss 1 (2024)

Subject Terms: Helicobacter pylori, gastric cancer, inflammation, biomarkers, premalignant, proteomics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/7753176891d94092ac155dd69412c031

Lysolipids are prominent in subretinal drusenoid deposits, a high-risk phenotype in age-related macular degeneration

Authors: David M. G. Anderson, Ankita Kotnala, Lukasz G. Migas, N. Heath Patterson, Léonore E. M. Tideman, Dongfeng Cao, Bibek Adhikari, Jeffrey D. Messinger, Thomas Ach, Sara Tortorella, Raf Van de Plas, Christine A. Curcio, Kevin L. Schey

Source: Frontiers in Ophthalmology, Vol 3 (2023)

Subject Terms: age-related macular degeneration, imaging mass spectrometry, subretinal drusenoid deposit, retinal pigment epithelium, lysolipid, interpretable supervised machine learning, Medicine

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fopht.2023.1258734/full; https://doaj.org/toc/2674-0826

Access URL: https://doaj.org/article/26cf13097cc94e109442e9a1e0f3b623

Unbalanced redox status network as an early pathological event in congenital cataracts

Authors: Eloy Bejarano, Elizabeth A. Whitcomb, Rebecca L. Pfeiffer, Kristie L. Rose, Maria José Asensio, José Antonio Rodríguez-Navarro, Alejandro Ponce-Mora, Antolín Canto, Inma Almansa, Kevin L. Schey, Bryan W. Jones, Allen Taylor, Sheldon Rowan

Source: Redox Biology, Vol 66, Iss , Pp 102869- (2023)

Subject Terms: Cataracts, Ubiquitin, Redox status, Glutathione, Taurine, Proteomics, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231723002707; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/c11db368416d4869b614ebeb6daca586

Dehydroalanine and dehydrobutyrine in aging and cataractous lenses reveal site-specific consequences of spontaneous protein degradation

Authors: Jessica Paredes, Zhen Wang, Purvi Patel, Kristie L. Rose, Kevin L. Schey

Source: Frontiers in Ophthalmology, Vol 3 (2023)

Subject Terms: post-translational modifications, proteomics, lens, cataracts, aging, Medicine

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fopht.2023.1241001/full; https://doaj.org/toc/2674-0826

Access URL: https://doaj.org/article/accaec59125a4e678ff099cf32133487

Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation

Authors: Yvonne L. Latour, Johanna C. Sierra, Jordan L. Finley, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Thaddeus M. Smith, Kara M. McNamara, Paula B. Luis, Claus Schneider, Justin Jacobse, Jeremy A. Goettel, M. Wade Calcutt, Kristie L. Rose, Kevin L. Schey, Ginger L. Milne, Alberto G. Delgado, M. Blanca Piazuelo, Bindu D. Paul, Solomon H. Snyder, Alain P. Gobert, Keith T. Wilson

Source: JCI Insight, Vol 7, Iss 12 (2022)

Subject Terms: Gastroenterology, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/19c8a2f445654133870ff2cc83d6103c

Computational Structure Prediction for Antibody-Antigen Complexes From Hydrogen-Deuterium Exchange Mass Spectrometry: Challenges and Outlook

Authors: Minh H. Tran, Clara T. Schoeder, Kevin L. Schey, Jens Meiler

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: hydrogen-deuterium exchange mass spectrometry (HDX-MS), antibody-antigen interaction, epitope-paratope identification, protein-protein docking, structure modeling, integrative structural biology, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.859964/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/98120009382744eaa9778281ff4fac2d

Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflammation–driven gastric carcinogenesis

Authors: Jennifer M. Noto, M. Blanca Piazuelo, Shailja C. Shah, Judith Romero-Gallo, Jessica L. Hart, Chao Di, James D. Carmichael, Alberto G. Delgado, Alese E. Halvorson, Robert A. Greevy, Lydia E. Wroblewski, Ayushi Sharma, Annabelle B. Newton, Margaret M. Allaman, Keith T. Wilson, M. Kay Washington, M. Wade Calcutt, Kevin L. Schey, Bethany P. Cummings, Charles R. Flynn, Joseph P. Zackular, Richard M. Peek Jr.

Source: The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)

Subject Terms: Gastroenterology, Infectious disease, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/7d198f5f9fa7400583ab84388b9c0680

Lens Aquaporins in Health and Disease: Location is Everything!

Authors: Kevin L. Schey, Romell B. Gletten, Carla V. T. O’Neale, Zhen Wang, Rosica S. Petrova, Paul J. Donaldson

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: cataract, protein aging, aquaporin regulation, microcirculation system, water transport, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.882550/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/94cbc0e6f70d4a00ae9ae54f75833ed8

Loss of Corpus-Specific Lipids in Helicobacter pylori-Induced Atrophic Gastritis

Authors: Aung Soe Lin, Jennifer H. B. Shuman, Ankita Kotnala, Jeff A. Shaw, Amber C. Beckett, Jennifer L. Harvey, Michael Tuck, Beverly R. E. A. Dixon, Michelle L. Reyzer, Holly M. Scott Algood, Kevin L. Schey, M. Blanca Piazuelo, Timothy L. Cover

Source: mSphere, Vol 6, Iss 6 (2021)

Subject Terms: gastric cancer, atrophic gastritis, imaging mass spectrometry, chief cells, parietal cells, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/ff728ddff59e4b5fa22a4ed658651fbb

Imaging Cataract-Specific Peptides in Human Lenses

Authors: Kevin L. Schey, Zhen Wang, Kristie L. Rose, David M. G. Anderson

Source: Cells, Vol 11, Iss 24, p 4042 (2022)

Subject Terms: imaging mass spectrometry, ocular lens, protein degradation, cataract, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/24/4042; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/c46b74946ace4d03beb30e20a7bc6873

Hypusination Orchestrates the Antimicrobial Response of Macrophages

Authors: Alain P. Gobert, Jordan L. Finley, Yvonne L. Latour, Mohammad Asim, Thaddeus M. Smith, Thomas G. Verriere, Daniel P. Barry, Margaret M. Allaman, Alberto G. Delagado, Kristie L. Rose, M. Wade Calcutt, Kevin L. Schey, Johanna C. Sierra, M. Blanca Piazuelo, Raghavendra G. Mirmira, Keith T. Wilson

Source: Cell Reports, Vol 33, Iss 11, Pp 108510- (2020)

Subject Terms: macrophages, bacterial infection, innate immunity, hypusine, polyamines, Helicobacter pylori, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720314996; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/c676099b79ac40018987909502fd92db

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Authors: Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Source: Frontiers in Molecular Neuroscience, Vol 13 (2020)

Subject Terms: serotonin transporter, SERT interacting proteins, autism spectrum disorder (ASD), quantitative proteomic analysis, SERT regulation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2020.00089/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/229a00d78e494ae49ab6705f21b72c23

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level

Authors: Georgia Charkoftaki, Nicholas J. W. Rattray, Per E. Andrén, Richard M. Caprioli, Steve Castellino, Mark W. Duncan, Richard J. A. Goodwin, Kevin L. Schey, Sheerin K. Shahidi-Latham, Kirill A. Veselkov, Caroline H. Johnson, Vasilis Vasiliou

Source: Human Genomics, Vol 12, Iss 1, Pp 1-6 (2018)

Subject Terms: Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40246-018-0142-x; https://doaj.org/toc/1479-7364

Access URL: https://doaj.org/article/7368424fbc7c49c6acebb5cbffb8b825

Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway

Authors: Alain P. Gobert, Yvonne L. Latour, Mohammad Asim, Jordan L. Finley, Thomas G. Verriere, Daniel P. Barry, Ginger L. Milne, Paula B. Luis, Claus Schneider, Emilio S. Rivera, Kristie Lindsey-Rose, Kevin L. Schey, Alberto G. Delgado, Johanna C. Sierra, M. Blanca Piazuelo, Keith T. Wilson

Source: mBio, Vol 10, Iss 5 (2019)

Subject Terms: Helicobacter pylori, immune evasion, immunometabolism, innate immunity, macrophages, pathogenic bacteria, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/db50a92f548d4b85beae15ff68935760

Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis

Authors: Monique R. Bennett, Jinhui Dong, Robin G. Bombardi, Cinque Soto, Helen M. Parrington, Rachel S. Nargi, Clara T. Schoeder, Marcus B. Nagel, Kevin L. Schey, Jens Meiler, Eric P. Skaar, James E. Crowe

Source: mBio, Vol 10, Iss 5 (2019)

Subject Terms: Staphylococcus aureus, X-ray crystallography, adaptive immunity, antibody functions, antibody repertoire, computer modeling, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/633528a5968b43209963b3d7f2daa1df

Use of Proteomic Imaging Coupled With Transcriptomic Analysis to Identify Biomolecules Responsive to Cochlear Injury

Authors: Kenyaria V. Noble, Michelle L. Reyzer, Jeremy L. Barth, Hayes McDonald, Michael Tuck, Kevin L. Schey, Edward L. Krug, Hainan Lang

Source: Frontiers in Molecular Neuroscience, Vol 11 (2018)

Subject Terms: cochlea, hearing loss, MALDI-TOF IMS, microarray, noise, ouabain, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2018.00243/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/9eb865eabfad4e778317c0d8e780712c

Identification of Immunoreactive Tumour Antigens Using Free and Exosome-Associated Humoral Responses

Authors: Carolyn D. Roberson, Cicek Gercel-Taylor, Ying Qi, Kevin L. Schey, Douglas D. Taylor

Source: Journal of Circulating Biomarkers, Vol 1 (2013)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1849-4544

Access URL: https://doaj.org/article/f6dc226e39694f619443ff9f38e83db0

Quantification of Protein Expression Changes in the Aging Left Ventricle of Rattus norvegicus.

Authors: Jennifer E. Grant, Amy D. Bradshaw, John H. Schwacke, Catalin F. Baicu, Michael R. Zile, Kevin L. Schey

Source: Journal of Proteome Research; Sep2009, Vol. 8 Issue 9, p4252-4263, 12p

A Statistical Model for iTRAQ Data Analysis.

Authors: Elizabeth G. Hill, John H. Schwacke, Susana Comte-Walters, Elizabeth H. Slate, Ann L. Oberg, Jeanette E. Eckel-Passow, Terry M. Therneau, Kevin L. Schey

Source: Journal of Proteome Research; Jul2008, Vol. 7 Issue 8, p3091-3101, 11p

Spatial Differences in an Integral Membrane Proteome Detected in Laser Capture Microdissected Samples.

Authors: Zhen Wang, Jun Han, Kevin L Schey

Source: Journal of Proteome Research; May2008, Vol. 7 Issue 7, p2696-2702, 7p