Extracellular vesicles promote activation of pro-inflammatory cancer-associated fibroblasts in oral cancer

Authors: Julia Arebro, Rebecca Towle, Che-Min Lee, Kevin L. Bennewith, Cathie Garnis

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: cancer-associated fibroblast, tumor microenvironment, oral squamous cell carcinoma, extracellular vesicles, inflammation, tumorigenesis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1240159/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/39b40ddacc8945859dd659e02742106c

Development and validation of an advanced ex vivo brain slice invasion assay to model glioblastoma cell invasion into the complex brain microenvironment

Authors: Lisa R. Decotret, Rocky Shi, Kiersten N. Thomas, Manchi Hsu, Catherine J. Pallen, Kevin L. Bennewith

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: organotypic brain slice culture, brain microenvironment, invasion, metastasis, glioblastoma multiforme, confocal microscopy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.976945/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/8df087dba80a434fb6e21bfef215d29d

Induced Vascular Normalization—Can One Force Tumors to Surrender to a Better Microenvironment?

Authors: Xu Xin Sun, Zeynab Nosrati, Janell Ko, Che-Min Lee, Kevin L. Bennewith, Marcel B. Bally

Source: Pharmaceutics, Vol 15, Iss 8, p 2022 (2023)

Subject Terms: cancer angiogenesis, nanomedicine, tumor vascular normalization, immune cells, immunotherapy, drug repurposing, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/8/2022; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/eb99b9eb33a04b9c94d4b5bce8a95c81

Loss of Parkinson’s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

Authors: Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A. Cederberg, Norman Chow, Nancy Dos Santos, Kevin L. Bennewith, Brad H. Nelson, Marcel B. Bally, Wan L. Lam, Sharon M. Gorski

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a628231eefc547ca89a67c8ce3fcdf31

Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth

Authors: Rachel A. Cederberg, Sarah Elizabeth Franks, Brennan J. Wadsworth, Alvina So, Lisa R. Decotret, Michael G. Hall, Rocky Shi, Michael R. Hughes, Kelly M. McNagny, Kevin L. Bennewith

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: eosinophil, lung metastasis, breast cancer, EO771, degranulation, interleukin-5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.841921/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/cdcf48cc602a4a0791bfc7101a827e71

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development

Authors: Etienne S. Melese, Elizabeth Franks, Rachel A. Cederberg, Bryant T. Harbourne, Rocky Shi, Brennan J. Wadsworth, Jenna L. Collier, Elizabeth C. Halvorsen, Fraser Johnson, Jennifer Luu, Min Hee Oh, Vivian Lam, Gerald Krystal, Shelley B. Hoover, Mark Raffeld, R. Mark Simpson, Arun M. Unni, Wan L. Lam, Stephen Lam, Ninan Abraham, Kevin L. Bennewith, William W. Lockwood

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: lung cancer, ccl5, tregs, oncogenes, egfr, kras, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/2c2a00203bef4e89885342925d64134f

Targeting myeloid-derived suppressor cells in combination with primary mammary tumor resection reduces metastatic growth in the lungs

Authors: Momir Bosiljcic, Rachel A. Cederberg, Melisa J. Hamilton, Nancy E. LePard, Bryant T. Harbourne, Jenna L. Collier, Elizabeth C. Halvorsen, Rocky Shi, S. Elizabeth Franks, Ada Y. Kim, Judit P. Banáth, Mark Hamer, Fabio M. Rossi, Kevin L. Bennewith

Source: Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)

Subject Terms: Myeloid-derived suppressor cells, Macrophages, Eosinophils, Metastasis, Tumor resection, Gemcitabine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13058-019-1189-x; https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/27a7a3ac6dc84010a63536a5241f3077

Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma

Authors: David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

Source: International Journal of Endocrinology, Vol 2014 (2014)

Subject Terms: Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/1687-8337; https://doaj.org/toc/1687-8345

Access URL: https://doaj.org/article/975faea950bb4960a30d67d54c64bc83

Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer

Authors: Natalie S Firmino, Rachel A Cederberg, Che-Min Lee, Rocky Shi, Brennan J Wadsworth, S Elizabeth Franks, Kiersten N Thomas, Lisa R Decotret, Kevin L Bennewith

Source: OncoImmunology, Vol 10, Iss 1 (2021)

Subject Terms: b cells, germinal centers, hypoxia, breast cancer, lymph nodes, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/564080d65da14b9aa13ca29d3b8f43bd