The effect of process parameters on a continuous blending process monitored in-line by near-infrared spectroscopy

Authors: Dias, Rute C., Korhonen, Ossi, Ketolainen, Jarkko, Ervasti, Tuomas, Lopes, João A.

Source: In European Journal of Pharmaceutical Sciences 1 November 2024 202

Continuous direct compression of a commercially batch-manufactured tablet formulation with two different processing lines

Authors: Lyytikäinen, Jenna, Stasiak, Pawel, Kubelka, Tomáš, Bogaerts, Ivan, Wanek, Adam, Stynen, Bart, Holman, James, Ketolainen, Jarkko, Ervasti, Tuomas, Korhonen, Ossi

Source: In European Journal of Pharmaceutics and Biopharmaceutics June 2024 199

High-speed optical observations of asymmetric pulsations of microbubbles released from tablet matrix

Authors: Anderton Nicole, Carlson Craig S., Xinyue Hu, Otake Naoyuki, Sorjonen Joona, Kudo Nobuki, Ketolainen Jarkko, Postema Michiel

Source: Current Directions in Biomedical Engineering, Vol 9, Iss 1, Pp 25-28 (2023)

Subject Terms: micro-crystalline cellulose, mcc tablet matrix, controlled gas release, rayleigh-plesset equation, buckling, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2364-5504

Access URL: https://doaj.org/article/829ee114ae7c4f81a584d9850eb6bdd2

Challenges encountered in the transfer of atorvastatin tablet manufacturing - commercial batch-based production as a basis for small-scale continuous tablet manufacturing tests

Authors: Lyytikäinen, Jenna ^{a, ⁎}, Kyllönen, Saini ^a, Ervasti, Tuomas ^a, Komulainen, Eelis ^a, Pekarek, Tomáš ^b, Slunečková, Jitka ^b, Leskinen, Jari ^c, Ketolainen, Jarkko ^a, Kubelka, Tomáš ^b, Stasiak, Pawel ^b, Korhonen, Ossi ^a

Source: In International Journal of Pharmaceutics 25 November 2023 647

Flowsheet modelling of a powder continuous feeder-mixer system

Authors: Dias, Rute C. ^{a, b, ⁎}, Korhonen, Ossi ^a, Ketolainen, Jarkko ^a, Lopes, João A. ^b, Ervasti, Tuomas ^a

Source: In International Journal of Pharmaceutics 25 May 2023 639

Detecting different amorphous – Amorphous phase separation patterns in co-amorphous mixtures with high resolution imaging FTIR spectroscopy

Authors: Kilpeläinen, Tuomas, Ervasti, Tuomas, Uurasjärvi, Emilia, Koistinen, Arto, Ketolainen, Jarkko, Korhonen, Ossi, Pajula, Katja

Source: In European Journal of Pharmaceutics and Biopharmaceutics November 2022 180:161-169

Faster to First-time-in-Human: Prediction of the liquid solid ratio for continuous wet granulation

Authors: Junnila, Atte, Wikström, Håkan, Megarry, Andrew, Gholami, Aida, Papathanasiou, Foteini, Blomberg, Andreas, Ketolainen, Jarkko, Tajarobi, Pirjo

Source: In European Journal of Pharmaceutical Sciences 1 May 2022 172

Preparation and characterization of hot-melt extruded polycaprolactone-based filaments intended for 3D-printing of tablets

Authors: Viidik, Laura, Vesala, Jemina, Laitinen, Riikka, Korhonen, Ossi, Ketolainen, Jarkko, Aruväli, Jaan, Kirsimäe, Kalle, Kogermann, Karin, Heinämäki, Jyrki, Laidmäe, Ivo, Ervasti, Tuomas

Source: In European Journal of Pharmaceutical Sciences 1 March 2021 158

Analysis of anisotropic pore structures using terahertz spectroscopy and imaging

Authors: Markl, Daniel, Ridgway, Cathy, Bawuah, Prince, Gane, Patrick, Ketolainen, Jarkko, Peiponen, Kai-Erik, Zeitler, J Axel

Source: 2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz) Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), 2017 42nd International Conference on. :1-1 Aug, 2017

Relation: 2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)

Comparison between twin-screw and high-shear granulation - The effect of filler and active pharmaceutical ingredient on the granule and tablet properties

Authors: Kyttä, Kaisa M., Lakio, Satu, Wikström, Håkan, Sulemanji, Anisa, Fransson, Magnus, Ketolainen, Jarkko, Tajarobi, Pirjo

Source: In Powder Technology October 2020 376:187-198

Converting a batch based high-shear granulation process to a continuous dry granulation process; a demonstration with ketoprofen tablets

Authors: Taipale-Kovalainen, Krista, Ketolainen, Jarkko, Korhonen, Ossi, Ervasti, Tuomas

Source: In European Journal of Pharmaceutical Sciences 1 August 2020 151

Comparison between integrated continuous direct compression line and batch processing – The effect of raw material properties

Authors: Karttunen, Anssi-Pekka, Wikström, Håkan, Tajarobi, Pirjo, Fransson, Magnus, Sparén, Anders, Marucci, Mariagrazia, Ketolainen, Jarkko, Folestad, Staffan, Korhonen, Ossi, Abrahmsén-Alami, Susanna

Source: In European Journal of Pharmaceutical Sciences 15 May 2019 133:40-53

The effects of unintentional and intentional process disturbances on tablet quality during long continuous manufacturing runs

Authors: Taipale-Kovalainen, Krista, Karttunen, Anssi-Pekka, Niinikoski, Hannes, Ketolainen, Jarkko, Korhonen, Ossi

Source: In European Journal of Pharmaceutical Sciences 1 March 2019 129:10-20

Resolving the rapid water absorption of porous functionalised calcium carbonate powder compacts by terahertz pulsed imaging

Authors: Markl, Daniel, Wang, Parry, Ridgway, Cathy, Karttunen, Anssi-Pekka, Bawuah, Prince, Ketolainen, Jarkko, Gane, Patrick, Peiponen, Kai-Erik, Zeitler, J. Axel

Source: In Chemical Engineering Research and Design April 2018 132:1082-1090

Lubricant based determination of design space for continuously manufactured high dose paracetamol tablets

Authors: Taipale-Kovalainen, Krista, Karttunen, Anssi-Pekka, Ketolainen, Jarkko, Korhonen, Ossi

Source: In European Journal of Pharmaceutical Sciences 30 March 2018 115:1-10

Efficient production of solid dispersions by spray drying solutions of high solid content using a 3-fluid nozzle

Authors: Kauppinen, Ari, Broekhuis, Joep, Grasmeijer, Niels, Tonnis, Wouter, Ketolainen, Jarkko, Frijlink, Henderik W., Hinrichs, Wouter L.J.

Source: In European Journal of Pharmaceutics and Biopharmaceutics February 2018 123:50-58

Measurement of residence time distributions and material tracking on three continuous manufacturing lines

Authors: Karttunen, Anssi-Pekka, Hörmann, Theresa R., De Leersnyder, Fien, Ketolainen, Jarkko, De Beer, Thomas, Hsiao, Wen-Kai, Korhonen, Ossi

Source: International journal of pharmaceutics. 563:184-197

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100082011250.0x000001&indx=1&recIds=ETOCvdc_100082011250.0x000001

Provoking an end-to-end continuous direct compression line with raw materials prone to segregation

Authors: Lakio, Satu, Ervasti, Tuomas, Tajarobi, Pirjo, Wikström, Håkan, Fransson, Magnus, Karttunen, Anssi-Pekka, Ketolainen, Jarkko, Folestad, Staffan, Abrahmsén-Alami, Susanna, Korhonen, Ossi

Source: In European Journal of Pharmaceutical Sciences 15 November 2017 109:514-524

Effect of storage on the physical stability of thin polymethacrylate-perphenazine films

Authors: Korhonen, Kristiina, Smolander, Elina, Korhonen, Ossi, Ketolainen, Jarkko, Laitinen, Riikka

Source: In European Journal of Pharmaceutical Sciences 15 June 2017 104:293-301

Characterization of the Pore Structure of Functionalized Calcium Carbonate Tablets by Terahertz Time-Domain Spectroscopy and X-Ray Computed Microtomography

Authors: Markl, Daniel, Wang, Parry, Ridgway, Cathy, Karttunen, Anssi-Pekka, Chakraborty, Mousumi, Bawuah, Prince, Pääkkönen, Pertti, Gane, Patrick, Ketolainen, Jarkko, Peiponen, Kai-Erik, Zeitler, J. Axel

Source: In Journal of Pharmaceutical Sciences June 2017 106(6):1586-1595