Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma

Authors: Tari, Haider ^{1, 2, 6}, Kessler, Ketty ^{2, 6}, Trahearn, Nick ¹, Werner, Benjamin ³, Vinci, Maria ⁴, Jones, Chris ^{2, 7, ∗}, Sottoriva, Andrea ^{1, 5, ∗∗}

Source: In Cell Reports 30 August 2022 40(9)

Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein, predispose to inherited thoracic aortic aneurysm

Authors: Elbitar, Sandy, Renard, Marjolijn, Arnaud, Pauline, Hanna, Nadine, Jacob, Marie-Paule, Guo, Dong-Chuan, Tsutsui, Ko, Gross, Marie-Sylvie, Kessler, Ketty, Tosolini, Laurent, Dattilo, Vincenzo, Dupont, Sebastien, Jonquet, Jeremie, Langeois, Maud, Benarroch, Louise, Aubart, Melodie, Ghaleb, Youmna, Abou Khalil, Yara, Varret, Mathilde, El Khoury, Petra, Ho-Tin-Noé, Benoit, Alembik, Yves, Gaertner, Sébastien, Isidor, Bertrand, Gouya, Laurent, Milleron, Olivier, Sekiguchi, Kiyotoshi, Milewicz, Dianna, De Backer, Julie, Le Goff, Carine, Michel, Jean-Baptiste, Jondeau, Guillaume, Sakai, Lynn Y., Boileau, Catherine, Abifadel, Marianne

Source: In Genetics in Medicine January 2021 23(1):111-122

Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells

Authors: Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn, Pemberton, Helen, Lord, Christopher, Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley, Qin, Elizabeth, Ingram, Wendy, Moore, Andrew, Ng, Ho-Keung, Trabelsi, Saoussen, H'mida-Ben Brahim, Dorra, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry, Bridges, Leslie, Martin, Andrew, Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume, de Torres, Carmen, Cruz, Ofelia, Carcaboso, Angel, Monje, Michelle, Mackay, Alan, Jones, Chris

Source: Nature medicine. 24(8):1204-1215

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174860019.0x000001&indx=1&recIds=ETOCvdc_100174860019.0x000001

Transforming growth factor-β1 SMAD effectors and medial cell number in ascending aorta diseases

Authors: Aparecida-Silva, Rosemeire, Borges, Luciano Figueiredo, Kessler, Ketty, Dias, Ricardo Ribeiro, Moreira, Luiz Felipe Pinho, Kalil, Jorge, Gutierrez, Paulo Sampaio

Source: In Cardiovascular Pathology May-June 2016 25(3):240-246

MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

Authors: Carvalho, Diana, Mackay, Alan, Temelso, Sara, Izquierdo, Elisa, Fernandez, Elisabet Potente, Rogers, Rebecca, Boult, Jessica, Salom, Janat Fazal, Simon, Natalie, Clarke, Matthew, Molinari, Valeria, Kessler, Ketty, Burford, Anna, Bjerke, Lynn, Fofana, Mariama, Hubank, Michael, Pears, Jane, Moore, Andrew, Carcaboso, Angel Montero, Marshall, Lynley, Carceller, Fernando, Robinson, Simon, Hargrave, Darren, Vinci, Maria, Jones, Chris

Source: Neuro-oncology. 22(Supplement 3):iii414-iii415

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112163635.0x000001&indx=1&recIds=ETOCvdc_100112163635.0x000001

DIPG-63. LOSS OF THE H4 LYSINE METHYLTRANSFERASE KMT5B DRIVES INVASION / MIGRATION BY DEPLETING H3K27me3 AT LOCI OTHERWISE RETAINED IN H3K27M MUTANT DIPG CELLS

Authors: Kessler, Ketty, Mackay, Alan, Molinari, Valeria, Tari, Haider, Burford, Anna, Sottoriva, Andrea, Vinci, Maria, Jones, Chris

Source: Neuro-oncology. 22(Supplement 3):iii299-iii300

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112156595.0x000001&indx=1&recIds=ETOCvdc_100112156595.0x000001

PDTM-31. DRUG SCREENING LINKED TO MOLECULAR PROFILING IDENTIFIES NOVEL DEPENDENCIES IN PATIENT-DERIVED PRIMARY CULTURES OF PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

Authors: Mackay, Alan, Carvalho, Diana, Molinari, Valeria, Pemberton, Helen, Temelso, Sara, Burford, Anna, Clarke, Matthew, Fofana, Mariama, Boult, Jessica, Izquierdo, Elisa, Taylor, Katy, Bjerke, Lynn, Fazal Salom, Janat, Kessler, Ketty, Rogers, Rebecca, Marshall, Lynley, Carceller, Fernando, Pears, Jane, Moore, Andrew, Miele, Evelina, Carai, Andrea, Mastronuzzi, Angela, Robinson, Simon, Lord, Chris, Olaciregui, Nagore, Mora, Jaume, Montero Carcaboso, Angel, Hargrave, Darren, Vinci, Maria, Jones, Chris

Source: Neuro-oncology. 20(suppl 6):vi210-vi210

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094740476.0x000001&indx=1&recIds=ETOCvdc_100094740476.0x000001

MFAP5 Loss-of-Function Mutations Underscore the Involvement of Matrix Alteration in the Pathogenesis of Familial Thoracic Aortic Aneurysms and Dissections

Authors: Barbier, Mathieu, Gross, Marie-Sylvie, Aubart, Mélodie, Hanna, Nadine, Kessler, Ketty, Guo, Dong-Chuan, Tosolini, Laurent, Ho-Tin-Noe, Benoit, Regalado, Ellen, Varret, Mathilde, Abifadel, Marianne, Milleron, Olivier, Odent, Sylvie, Dupuis-Girod, Sophie, Faivre, Laurence, Edouard, Thomas, Dulac, Yves, Busa, Tiffany, Gouya, Laurent, Milewicz, Dianna M., Jondeau, Guillaume, Boileau, Catherine

Source: In The American Journal of Human Genetics 4 December 2014 95(6):736-743

This result is not displayed to guests.
Login for full access.

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.

Authors: Singh, Shalini, Howell, Danielle, Trivedi, Niraj, Kessler, Ketty, Ong, Taren, Rosmaninho, Pedro, Raposo, Alexandre A. S. F., Robinson, Giles, Roussel, Martine F., Castro, Diogo S., Solecki, David J.

Source: eLife; 2016, p1-31, 31p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

DIPG-08. THE ROLE OF KMT5B/C AND H4K20 DI/TRIMETHYLATION IN DIPG.

Authors: Kessler, Ketty, Mackay, Alan, Molinari, Valeria, Burford, Anna, Bjerke, Lynn, Temelso, Sara, Vinci, Mara, Jones, Chris

Source: Neuro-Oncology; 2019 Supplement, Vol. 21, pii69-ii70, 2p