Proteomic prediction of diverse incident diseases: a machine learning-guided biomarker discovery study using data from a prospective cohort study

Authors: Carrasco-Zanini, Julia ^{a, c, *}, Pietzner, Maik ^{a, b, c, *}, Koprulu, Mine ^a, Wheeler, Eleanor ^a, Kerrison, Nicola D ^a, Wareham, Nicholas J ^a, Langenberg, Claudia ^{a, b, c, *}

Source: In The Lancet Digital Health July 2024 6(7):e470-e479

Damaging missense variants in IGF1R implicate a role for IGF-1 resistance in the etiology of type 2 diabetes

Authors: Gardner, Eugene J., Kentistou, Katherine A., Stankovic, Stasa, Lockhart, Samuel, Wheeler, Eleanor, Day, Felix R., Kerrison, Nicola D., Wareham, Nicholas J., Langenberg, Claudia, O'Rahilly, Stephen, Ong, Ken K., Perry, John R.B.

Source: In Cell Genomics 14 December 2022 2(12)

Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution

Authors: Koprulu, Mine, Zhao, Yajie, Wheeler, Eleanor, Dong, Liang, Rocha, Nuno, Li, Chen, Griffin, John D, Patel, Satish, Van de Streek, Marcel, Glastonbury, Craig A, Stewart, Isobel D, Day, Felix R, Luan, Jian'an, Bowker, Nicholas, Wittemans, Laura B L, Kerrison, Nicola D, Cai, Lina, Lucarelli, Debora M E, Barroso, Inês, McCarthy, Mark I, Scott, Robert A, Saudek, Vladimir, Small, Kerrin S, Wareham, Nicholas J, Semple, Robert K, Perry, John R B, O'Rahilly, Stephen, Lotta, Luca A, Langenberg, Claudia, Savage, David B

Source: Journal of clinical endocrinology & metabolism. 107(4):1065-1077

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152519996.0x000001&indx=1&recIds=ETOCvdc_100152519996.0x000001

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

Authors: Li, Chen, Stoma, Svetlana, Lotta, Luca A., Warner, Sophie, Albrecht, Eva, Allione, Alessandra, Arp, Pascal P., Broer, Linda, Buxton, Jessica L., Da Silva Couto Alves, Alexessander, Deelen, Joris, Fedko, Iryna O., Gordon, Scott D., Jiang, Tao, Karlsson, Robert, Kerrison, Nicola, Loe, Taylor K., Mangino, Massimo, Milaneschi, Yuri, Miraglio, Benjamin, Pervjakova, Natalia, Russo, Alessia, Surakka, Ida, van der Spek, Ashley, Verhoeven, Josine E., Amin, Najaf, Beekman, Marian, Blakemore, Alexandra I., Canzian, Federico, Hamby, Stephen E., Hottenga, Jouke-Jan, Jones, Peter D., Jousilahti, Pekka, Mägi, Reedik, Medland, Sarah E., Montgomery, Grant W., Nyholt, Dale R., Perola, Markus, Pietiläinen, Kirsi H., Salomaa, Veikko, Sillanpää, Elina, Suchiman, H. Eka, van Heemst, Diana, Willemsen, Gonneke, Agudo, Antonio, Boeing, Heiner, Boomsma, Dorret I., Chirlaque, Maria-Dolores, Fagherazzi, Guy, Ferrari, Pietro, Franks, Paul, Gieger, Christian, Eriksson, Johan Gunnar, Gunter, Marc, Hägg, Sara, Hovatta, Iiris, Imaz, Liher, Kaprio, Jaakko, Kaaks, Rudolf, Key, Timothy, Krogh, Vittorio, Martin, Nicholas G., Melander, Olle, Metspalu, Andres, Moreno, Concha, Onland-Moret, N. Charlotte, Nilsson, Peter, Ong, Ken K., Overvad, Kim, Palli, Domenico, Panico, Salvatore, Pedersen, Nancy L., Penninx, Brenda W.J. H., Quirós, J. Ramón, Jarvelin, Marjo Riitta, Rodríguez-Barranco, Miguel, Scott, Robert A., Severi, Gianluca, Slagboom, P. Eline, Spector, Tim D., Tjonneland, Anne, Trichopoulou, Antonia, Tumino, Rosario, Uitterlinden, André G., van der Schouw, Yvonne T., van Duijn, Cornelia M., Weiderpass, Elisabete, Denchi, Eros Lazzerini, Matullo, Giuseppe, Butterworth, Adam S., Danesh, John, Samani, Nilesh J., Wareham, Nicholas J., Nelson, Christopher P., Langenberg, Claudia, Codd, Veryan

Source: In The American Journal of Human Genetics 5 March 2020 106(3):389-404

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity

Authors: Lotta, Luca A., Mokrosiński, Jacek, Mendes de Oliveira, Edson, Li, Chen, Sharp, Stephen J., Luan, Jian’an, Brouwers, Bas, Ayinampudi, Vikram, Bowker, Nicholas, Kerrison, Nicola, Kaimakis, Vasileios, Hoult, Diana, Stewart, Isobel D., Wheeler, Eleanor, Day, Felix R., Perry, John R.B., Langenberg, Claudia, Wareham, Nicholas J., Farooqi, I. Sadaf

Source: In Cell 18 April 2019 177(3):597-607

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Authors: Kraja, Aldi T., Liu, Chunyu, Fetterman, Jessica L., Graff, Mariaelisa, Have, Christian Theil, Gu, Charles, Yanek, Lisa R., Feitosa, Mary F., Arking, Dan E., Chasman, Daniel I., Young, Kristin, Ligthart, Symen, Hill, W. David, Weiss, Stefan, Luan, Jian’an, Giulianini, Franco, Li-Gao, Ruifang, Hartwig, Fernando P., Lin, Shiow J., Wang, Lihua, Richardson, Tom G., Yao, Jie, Fernandez, Eliana P., Ghanbari, Mohsen, Wojczynski, Mary K., Lee, Wen-Jane, Argos, Maria, Armasu, Sebastian M., Barve, Ruteja A., Ryan, Kathleen A., An, Ping, Baranski, Thomas J., Bielinski, Suzette J., Bowden, Donald W., Broeckel, Ulrich, Christensen, Kaare, Chu, Audrey Y., Corley, Janie, Cox, Simon R., Uitterlinden, Andre G., Rivadeneira, Fernando, Cropp, Cheryl D., Daw, E. Warwick, van Heemst, Diana, de las Fuentes, Lisa, Gao, He, Tzoulaki, Ioanna, Ahluwalia, Tarunveer S., de Mutsert, Renée, Emery, Leslie S., Erzurumluoglu, A. Mesut, Perry, James A., Fu, Mao, Forouhi, Nita G., Gu, Zhenglong, Hai, Yang, Harris, Sarah E., Hemani, Gibran, Hunt, Steven C., Irvin, Marguerite R., Jonsson, Anna E., Justice, Anne E., Kerrison, Nicola D., Larson, Nicholas B., Lin, Keng-Hung, Love-Gregory, Latisha D., Mathias, Rasika A., Lee, Joseph H., Nauck, Matthias, Noordam, Raymond, Ong, Ken K., Pankow, James, Patki, Amit, Pattie, Alison, Petersmann, Astrid, Qi, Qibin, Ribel-Madsen, Rasmus, Rohde, Rebecca, Sandow, Kevin, Schnurr, Theresia M., Sofer, Tamar, Starr, John M., Taylor, Adele M., Teumer, Alexander, Timpson, Nicholas J., de Haan, Hugoline G., Wang, Yujie, Weeke, Peter E., Williams, Christine, Wu, Hongsheng, Yang, Wei, Zeng, Donglin, Witte, Daniel R., Weir, Bruce S., Wareham, Nicholas J., Vestergaard, Henrik, Turner, Stephen T., Torp-Pedersen, Christian, Stergiakouli, Evie, Sheu, Wayne Huey-Herng, Rosendaal, Frits R., Ikram, M. Arfan, Franco, Oscar H., Ridker, Paul M., Perls, Thomas T., Pedersen, Oluf, Nohr, Ellen A., Newman, Anne B., Linneberg, Allan, Langenberg, Claudia, Kilpeläinen, Tuomas O., Kardia, Sharon L.R., Jørgensen, Marit E., Jørgensen, Torben, Sørensen, Thorkild I.A., Homuth, Georg, Hansen, Torben, Goodarzi, Mark O., Deary, Ian J., Christensen, Cramer, Chen, Yii-Der Ida, Chakravarti, Aravinda, Brandslund, Ivan, Bonnelykke, Klaus, Taylor, Kent D., Wilson, James G., Rodriguez, Santiago, Davies, Gail, Horta, Bernardo L., Thyagarajan, Bharat, Rao, D.C., Grarup, Niels, Davila-Roman, Victor G., Hudson, Gavin, Guo, Xiuqing, Arnett, Donna K., Hayward, Caroline, Vaidya, Dhananjay, Mook-Kanamori, Dennis O., Tiwari, Hemant K., Levy, Daniel, Loos, Ruth J.F., Dehghan, Abbas, Elliott, Paul, Malik, Afshan N., Scott, Robert A., Becker, Diane M., de Andrade, Mariza, Province, Michael A., Meigs, James B., Rotter, Jerome I., North, Kari E.

Source: In The American Journal of Human Genetics 3 January 2019 104(1):112-138

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

Authors: Sung, Yun J., Winkler, Thomas W., de las Fuentes, Lisa, Bentley, Amy R., Brown, Michael R., Kraja, Aldi T., Schwander, Karen, Ntalla, Ioanna, Guo, Xiuqing, Franceschini, Nora, Lu, Yingchang, Cheng, Ching-Yu, Sim, Xueling, Vojinovic, Dina, Marten, Jonathan, Musani, Solomon K., Li, Changwei, Feitosa, Mary F., Kilpeläinen, Tuomas O., Richard, Melissa A., Noordam, Raymond, Aslibekyan, Stella, Aschard, Hugues, Bartz, Traci M., Dorajoo, Rajkumar, Liu, Yongmei, Manning, Alisa K., Rankinen, Tuomo, Smith, Albert Vernon, Tajuddin, Salman M., Tayo, Bamidele O., Warren, Helen R., Zhao, Wei, Zhou, Yanhua, Matoba, Nana, Sofer, Tamar, Alver, Maris, Amini, Marzyeh, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Gandin, Ilaria, Gao, Chuan, Giulianini, Franco, Goel, Anuj, Harris, Sarah E., Hartwig, Fernando Pires, Horimoto, Andrea R.V.R., Hsu, Fang-Chi, Jackson, Anne U., Kähönen, Mika, Kasturiratne, Anuradhani, Kühnel, Brigitte, Leander, Karin, Lee, Wen-Jane, Lin, Keng-Hung, ’an Luan, Jian, McKenzie, Colin A., Meian, He, Nelson, Christopher P., Rauramaa, Rainer, Schupf, Nicole, Scott, Robert A., Sheu, Wayne H.H., Stančáková, Alena, Takeuchi, Fumihiko, van der Most, Peter J., Varga, Tibor V., Wang, Heming, Wang, Yajuan, Ware, Erin B., Weiss, Stefan, Wen, Wanqing, Yanek, Lisa R., Zhang, Weihua, Zhao, Jing Hua, Afaq, Saima, Alfred, Tamuno, Amin, Najaf, Arking, Dan, Aung, Tin, Barr, R. Graham, Bielak, Lawrence F., Boerwinkle, Eric, Bottinger, Erwin P., Braund, Peter S., Brody, Jennifer A., Broeckel, Ulrich, Cabrera, Claudia P., Cade, Brian, Caizheng, Yu, Campbell, Archie, Canouil, Mickaël, Chakravarti, Aravinda, Chauhan, Ganesh, Christensen, Kaare, Cocca, Massimiliano, Collins, Francis S., Connell, John M., de Mutsert, Renée, de Silva, H. Janaka, Debette, Stephanie, Dörr, Marcus, Duan, Qing, Eaton, Charles B., Ehret, Georg, Evangelou, Evangelos, Faul, Jessica D., Fisher, Virginia A., Forouhi, Nita G., Franco, Oscar H., Friedlander, Yechiel, Gao, He, Gigante, Bruna, Graff, Misa, Gu, C. Charles, Gu, Dongfeng, Gupta, Preeti, Hagenaars, Saskia P., Harris, Tamara B., He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hirata, Makoto, Hofman, Albert, Howard, Barbara V., Hunt, Steven, Irvin, Marguerite R., Jia, Yucheng, Joehanes, Roby, Justice, Anne E., Katsuya, Tomohiro, Kaufman, Joel, Kerrison, Nicola D., Khor, Chiea Chuen, Koh, Woon-Puay, Koistinen, Heikki A., Komulainen, Pirjo, Kooperberg, Charles, Krieger, Jose E., Kubo, Michiaki, Kuusisto, Johanna, Langefeld, Carl D., Langenberg, Claudia, Launer, Lenore J., Lehne, Benjamin, Lewis, Cora E., Li, Yize, Lim, Sing Hui, Lin, Shiow, Liu, Ching-Ti, Liu, Jianjun, Liu, Jingmin, Liu, Kiang, Liu, Yeheng, Loh, Marie, Lohman, Kurt K., Long, Jirong, Louie, Tin, Mägi, Reedik, Mahajan, Anubha, Meitinger, Thomas, Metspalu, Andres, Milani, Lili, Momozawa, Yukihide, Morris, Andrew P., Mosley, Thomas H., Jr., Munson, Peter, Murray, Alison D., Nalls, Mike A., Nasri, Ubaydah, Norris, Jill M., North, Kari, Ogunniyi, Adesola, Padmanabhan, Sandosh, Palmas, Walter R., Palmer, Nicholette D., Pankow, James S., Pedersen, Nancy L., Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Raitakari, Olli T., Renström, Frida, Rice, Treva K., Ridker, Paul M., Robino, Antonietta, Robinson, Jennifer G., Rose, Lynda M., Rudan, Igor, Sabanayagam, Charumathi, Salako, Babatunde L., Sandow, Kevin, Schmidt, Carsten O., Schreiner, Pamela J., Scott, William R., Seshadri, Sudha, Sever, Peter, Sitlani, Colleen M., Smith, Jennifer A., Snieder, Harold, Starr, John M., Strauch, Konstantin, Tang, Hua, Taylor, Kent D., Teo, Yik Ying, Tham, Yih Chung, Uitterlinden, André G., Waldenberger, Melanie, Wang, Lihua, Wang, Ya X., Wei, Wen Bin, Williams, Christine, Wilson, Gregory, Wojczynski, Mary K., Yao, Jie, Yuan, Jian-Min, Zonderman, Alan B., Becker, Diane M., Boehnke, Michael, Bowden, Donald W., Chambers, John C., Chen, Yii-Der Ida, de Faire, Ulf, Deary, Ian J., Esko, Tõnu, Farrall, Martin, Forrester, Terrence, Franks, Paul W., Freedman, Barry I., Froguel, Philippe, Gasparini, Paolo, Gieger, Christian, Horta, Bernardo Lessa, Hung, Yi-Jen, Jonas, Jost B., Kato, Norihiro, Kooner, Jaspal S., Laakso, Markku, Lehtimäki, Terho, Liang, Kae-Woei, Magnusson, Patrik K.E., Newman, Anne B., Oldehinkel, Albertine J., Pereira, Alexandre C., Redline, Susan, Rettig, Rainer, Samani, Nilesh J., Scott, James, Shu, Xiao-Ou, van der Harst, Pim, Wagenknecht, Lynne E., Wareham, Nicholas J., Watkins, Hugh, Weir, David R., Wickremasinghe, Ananda R., Wu, Tangchun, Zheng, Wei, Kamatani, Yoichiro, Laurie, Cathy C., Bouchard, Claude, Cooper, Richard S., Evans, Michele K., Gudnason, Vilmundur, Kardia, Sharon L.R., Kritchevsky, Stephen B., Levy, Daniel, O’Connell, Jeff R., Psaty, Bruce M., van Dam, Rob M., Sims, Mario, Arnett, Donna K., Mook-Kanamori, Dennis O., Kelly, Tanika N., Fox, Ervin R., Hayward, Caroline, Fornage, Myriam, Rotimi, Charles N., Province, Michael A., van Duijn, Cornelia M., Tai, E. Shyong, Wong, Tien Yin, Loos, Ruth J.F., Reiner, Alex P., Rotter, Jerome I., Zhu, Xiaofeng, Bierut, Laura J., Gauderman, W. James, Caulfield, Mark J., Elliott, Paul, Rice, Kenneth, Munroe, Patricia B., Morrison, Alanna C., Cupples, L. Adrienne, Rao, Dabeeru C., Chasman, Daniel I.

Source: In The American Journal of Human Genetics 1 March 2018 102(3):375-400

Genetic predisposition to mosaic Y chromosome loss in blood

Authors: Thompson, Deborah, Genovese, Giulio, Halvardson, Jonatan, Ulirsch, Jacob, Wright, Daniel, Terao, Chikashi, Davidsson, Olafur, Day, Felix, Sulem, Patrick, Jiang, Yunxuan, Danielsson, Marcus, Davies, Hanna, Dennis, Joe, Dunlop, Malcolm, Easton, Douglas, Fisher, Victoria, Zink, Florian, Houlston, Richard, Ingelsson, Martin, Kar, Siddhartha, Kerrison, Nicola, Kinnersley, Ben, Kristjansson, Ragnar, Law, Philip, Li, Rong, Loveday, Chey, Mattisson, Jonas, McCarroll, Steven, Murakami, Yoshinori, Murray, Anna, Olszewski, Pawel, Rychlicka-Buniowska, Edyta, Scott, Robert, Thorsteinsdottir, Unnur, Tomlinson, Ian, Moghadam, Behrooz, Turnbull, Clare, Wareham, Nicholas, Gudbjartsson, Daniel, Kamatani, Yoichiro, Hoffmann, Eva, Jackson, Steve, Stefansson, Kari, Auton, Adam, Ong, Ken, Machiela, Mitchell, Loh, Po-Ru, Dumanski, Jan, Chanock, Stephen, Forsberg, Lars, Perry, John

Source: Nature. 575(7784):652-657

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190904301.0x000001&indx=1&recIds=ETOCvdc_100190904301.0x000001

Associations of autozygosity with a broad range of human phenotypes

Authors: Clark, David, Okada, Yukinori, Moore, Kristjan, Mason, Dan, Pirastu, Nicola, Gandin, Ilaria, Mattsson, Hannele, Barnes, Catriona, Lin, Kuang, Zhao, Jing, Deelen, Patrick, Rohde, Rebecca, Schurmann, Claudia, Guo, Xiuqing, Giulianini, Franco, Zhang, Weihua, Medina-Gomez, Carolina, Karlsson, Robert, Bao, Yanchun, Bartz, Traci, Baumbach, Clemens, Biino, Ginevra, Bixley, Matthew, Brumat, Marco, Chai, Jin-Fang, Corre, Tanguy, Cousminer, Diana, Dekker, Annelot, Eccles, David, Eijk, Kristel, Fuchsberger, Christian, Gao, He, Germain, Marine, Gordon, Scott, Haan, Hugoline, Harris, Sarah, Hofer, Edith, Huerta-Chagoya, Alicia, Igartua, Catherine, Jansen, Iris, Jia, Yucheng, Kacprowski, Tim, Karlsson, Torgny, Kleber, Marcus, Li, Shengchao, Li-Gao, Ruifang, Mahajan, Anubha, Matsuda, Koichi, Meidtner, Karina, Meng, Weihua, Montasser, May, Most, Peter, Munz, Matthias, Nutile, Teresa, Palviainen, Teemu, Prasad, Gauri, Prasad, Rashmi, Priyanka, Tallapragada, Rizzi, Federica, Salvi, Erika, Sapkota, Bishwa, Shriner, Daniel, Skotte, Line, Smart, Melissa, Smith, Albert, Spek, Ashley, Spracklen, Cassandra, Strawbridge, Rona, Tajuddin, Salman, Trompet, Stella, Turman, Constance, Verweij, Niek, Viberti, Clara, Wang, Lihua, Warren, Helen, Wootton, Robyn, Yanek, Lisa, Yao, Jie, Yousri, Noha, Zhao, Wei, Adeyemo, Adebowale, Afaq, Saima, Aguilar-Salinas, Carlos, Akiyama, Masato, Albert, Matthew, Allison, Matthew, Alver, Maris, Aung, Tin, Azizi, Fereidoun, Bentley, Amy, Boeing, Heiner, Boerwinkle, Eric, Borja, Judith, Borst, Gert, Bottinger, Erwin, Broer, Linda, Campbell, Harry, Chanock, Stephen, Chee, Miao-Li, Chen, Guanjie, Chen, Yii-Der, Chen, Zhengming, Chiu, Yen-Feng, Cocca, Massimiliano, Collins, Francis, Concas, Maria, Corley, Janie, Cugliari, Giovanni, Dam, Rob, Damulina, Anna, Daneshpour, Maryam, Day, Felix, Delgado, Graciela, Dhana, Klodian, Doney, Alexander, Dörr, Marcus, Doumatey, Ayo, Dzimiri, Nduna, Ebenesersdóttir, S, Elliott, Joshua, Elliott, Paul, Ewert, Ralf, Felix, Janine, Fischer, Krista, Freedman, Barry, Girotto, Giorgia, Goel, Anuj, Gögele, Martin, Goodarzi, Mark, Graff, Mariaelisa, Granot-Hershkovitz, Einat, Grodstein, Francine, Guarrera, Simonetta, Gudbjartsson, Daniel, Guity, Kamran, Gunnarsson, Bjarni, Guo, Yu, Hagenaars, Saskia, Haiman, Christopher, Halevy, Avner, Harris, Tamara, Hedayati, Mehdi, Heel, David, Hirata, Makoto, Höfer, Imo, Hsiung, Chao, Huang, Jinyan, Hung, Yi-Jen, Ikram, M, Jagadeesan, Anuradha, Jousilahti, Pekka, Kamatani, Yoichiro, Kanai, Masahiro, Kerrison, Nicola, Kessler, Thorsten, Khaw, Kay-Tee, Khor, Chiea, Kleijn, Dominique, Koh, Woon-Puay, Kolcic, Ivana, Kraft, Peter, Krämer, Bernhard, Kutalik, Zoltán, Kuusisto, Johanna, Langenberg, Claudia, Launer, Lenore, Lawlor, Deborah, Lee, I-Te, Lee, Wen-Jane, Lerch, Markus, Li, Liming, Liu, Jianjun, Loh, Marie, London, Stephanie, Loomis, Stephanie, Lu, Yingchang, Luan, Jian'an, Mägi, Reedik, Manichaikul, Ani, Manunta, Paolo, Másson, Gísli, Matoba, Nana, Mei, Xue, Meisinger, Christa, Meitinger, Thomas, Mezzavilla, Massimo, Milani, Lili, Millwood, Iona, Momozawa, Yukihide, Moore, Amy, Morange, Pierre-Emmanuel, Moreno-Macías, Hortensia, Mori, Trevor, Morrison, Alanna, Muka, Taulant, Murakami, Yoshinori, Murray, Alison, Mutsert, Renée, Mychaleckyj, Josyf, Nalls, Mike, Nauck, Matthias, Neville, Matt, Nolte, Ilja, Ong, Ken, Orozco, Lorena, Padmanabhan, Sandosh, Pálsson, Gunnar, Pankow, James, Pattaro, Cristian, Pattie, Alison, Polasek, Ozren, Poulter, Neil, Pramstaller, Peter, Quintana-Murci, Lluis, Räikkönen, Katri, Ralhan, Sarju, Rao, Dabeeru, Rheenen, Wouter, Rich, Stephen, Ridker, Paul, Rietveld, Cornelius, Robino, Antonietta, Rooij, Frank, Ruggiero, Daniela, Saba, Yasaman, Sabanayagam, Charumathi, Sabater-Lleal, Maria, Sala, Cinzia, Salomaa, Veikko, Sandow, Kevin, Schmidt, Helena, Scott, Laura, Scott, William, Sedaghati-Khayat, Bahareh, Sennblad, Bengt, Setten, Jessica, Sever, Peter, Sheu, Wayne, Shi, Yuan, Shrestha, Smeeta, Shukla, Sharvari, Sigurdsson, Jon, Sikka, Timo, Singh, Jai, Smith, Blair, Stančáková, Alena, Stanton, Alice, Starr, John, Stefansdottir, Lilja, Straker, Leon, Sulem, Patrick, Sveinbjornsson, Gardar, Swertz, Morris, Taylor, Adele, Taylor, Kent, Terzikhan, Natalie, Tham, Yih-Chung, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Tillander, Annika, Tracy, Russell, Tusié-Luna, Teresa, Tzoulaki, Ioanna, Vaccargiu, Simona, Vangipurapu, Jagadish, Veldink, Jan, Vitart, Veronique, Völker, Uwe, Vuoksimaa, Eero, Wakil, Salma, Waldenberger, Melanie, Wander, Gurpreet, Wang, Ya, Wareham, Nicholas, Wild, Sarah, Yajnik, Chittaranjan, Yuan, Jian-Min, Zeng, Lingyao, Zhang, Liang, Zhou, Jie, Amin, Najaf, Asselbergs, Folkert, Bakker, Stephan, Becker, Diane, Lehne, Benjamin, Bennett, David, Berg, Leonard, Berndt, Sonja, Bharadwaj, Dwaipayan, Bielak, Lawrence, Bochud, Murielle, Boehnke, Mike, Bouchard, Claude, Bradfield, Jonathan, Brody, Jennifer, Campbell, Archie, Carmi, Shai, Caulfield, Mark, Cesarini, David, Chambers, John, Chandak, Giriraj, Cheng, Ching-Yu, Ciullo, Marina, Cornelis, Marilyn, Cusi, Daniele, Smith, George, Deary, Ian, Dorajoo, Rajkumar, Duijn, Cornelia, Ellinghaus, David, Erdmann, Jeanette, Eriksson, Johan, Evangelou, Evangelos, Evans, Michele, Faul, Jessica, Feenstra, Bjarke, Feitosa, Mary, Foisy, Sylvain, Franke, Andre, Friedlander, Yechiel, Gasparini, Paolo, Gieger, Christian, Gonzalez, Clicerio, Goyette, Philippe, Grant, Struan, Griffiths, Lyn, Groop, Leif, Gudnason, Vilmundur, Gyllensten, Ulf, Hakonarson, Hakon, Hamsten, Anders, Harst, Pim, Heng, Chew-Kiat, Hicks, Andrew, Hochner, Hagit, Huikuri, Heikki, Hunt, Steven, Jaddoe, Vincent, Jager, Philip, Johannesson, Magnus, Johansson, Åsa, Jonas, Jost, Jukema, J, Junttila, Juhani, Kaprio, Jaakko, Kardia, Sharon, Karpe, Fredrik, Kumari, Meena, Laakso, Markku, Laan, Sander, Lahti, Jari, Laudes, Matthias, Lea, Rodney, Lieb, Wolfgang, Lumley, Thomas, Martin, Nicholas, März, Winfried, Matullo, Giuseppe, McCarthy, Mark, Medland, Sarah, Merriman, Tony, Metspalu, Andres, Meyer, Brian, Mohlke, Karen, Montgomery, Grant, Mook-Kanamori, Dennis, Munroe, Patricia, North, Kari, Nyholt, Dale, O'connell, Jeffery, Ober, Carole, Oldehinkel, Albertine, Palmas, Walter, Palmer, Colin, Pasterkamp, Gerard, Patin, Etienne, Pennell, Craig, Perusse, Louis, Peyser, Patricia, Pirastu, Mario, Polderman, Tinca, Porteous, David, Posthuma, Danielle, Psaty, Bruce, Rioux, John, Rivadeneira, Fernando, Rotimi, Charles, Rotter, Jerome, Rudan, Igor, Ruijter, Hester, Sanghera, Dharambir, Sattar, Naveed, Schmidt, Reinhold, Schulze, Matthias, Schunkert, Heribert, Scott, Robert, Shuldiner, Alan, Sim, Xueling, Small, Neil, Smith, Jennifer, Sotoodehnia, Nona, Tai, E-Shyong, Teumer, Alexander, Timpson, Nicholas, Toniolo, Daniela, Tregouet, David-Alexandre, Tuomi, Tiinamaija, Vollenweider, Peter, Wang, Carol, Weir, David, Whitfield, John, Wijmenga, Cisca, Wong, Tien-Yin, Wright, John, Yang, Jingyun, Yu, Lei, Zemel, Babette, Zonderman, Alan, Perola, Markus, Magnusson, Patrik, Uitterlinden, André, Kooner, Jaspal, Chasman, Daniel, Loos, Ruth, Franceschini, Nora, Franke, Lude, Haley, Chris, Hayward, Caroline, Walters, Robin, Perry, John, Esko, Tōnu, Helgason, Agnar, Stefansson, Kari, Joshi, Peter, Kubo, Michiaki, Wilson, James

Source: Nature communications. 10(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190885123.0x000001&indx=1&recIds=ETOCvdc_100190885123.0x000001

Multi-omic prediction of incident type 2 diabetes.

Authors: Carrasco-Zanini, Julia, Pietzner, Maik, Wheeler, Eleanor, Kerrison, Nicola D., Langenberg, Claudia, Wareham, Nicholas J.

Source: Diabetologia; Jan2024, Vol. 67 Issue 1, p102-112, 11p

Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection

Authors: Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Raffler, Johannes, Kerrison, Nicola D., Oerton, Erin, Auyeung, Victoria P. W., Luan, Jian'an, Finan, Chris, Casas, Juan P., Ostroff, Rachel, Williams, Steve A., Kastenmüller, Gabi, Ralser, Markus, Gamazon, Eric R., Wareham, Nicholas J., Hingorani, Aroon D., Langenberg, Claudia

Source: Nature communications. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194057861.0x000001&indx=1&recIds=ETOCvdc_100194057861.0x000001

Genetic architecture of host proteins involved in SARS-CoV-2 infection

Authors: Pietzner, Maik, Wheeler, Eleanor, Carrasco-Zanini, Julia, Raffler, Johannes, Kerrison, Nicola D., Oerton, Erin, Auyeung, Victoria P. W., Luan, Jian'an, Finan, Chris, Casas, Juan P., Ostroff, Rachel, Williams, Steve A., Kastenmüller, Gabi, Ralser, Markus, Gamazon, Eric R., Wareham, Nicholas J., Hingorani, Aroon D., Langenberg, Claudia

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194190860.0x000001&indx=1&recIds=ETOCvdc_100194190860.0x000001

Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study

Authors: Cai, Lina, Wheeler, Eleanor, Kerrison, Nicola D., Luan, Jian'an, Deloukas, Panos, Franks, Paul W., Amiano, Pilar, Ardanaz, Eva, Bonet, Catalina, Fagherazzi, Guy, Groop, Leif C., Kaaks, Rudolf, Huerta, José María, Masala, Giovanna, Nilsson, Peter M., Overvad, Kim, Pala, Valeria, Panico, Salvatore, Rodriguez-Barranco, Miguel, Rolandsson, Olov, Sacerdote, Carlotta, Schulze, Matthias B., Spijkerman, Annemieke M. W., Tjonneland, Anne, Tumino, Rosario, van der Schouw, Yvonne T., Sharp, Stephen J., Forouhi, Nita G., Riboli, Elio, McCarthy, Mark I., Barroso, Inês, Langenberg, Claudia, Wareham, Nicholas J.

Source: Scientific data. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186943329.0x000001&indx=1&recIds=ETOCvdc_100186943329.0x000001

Causal associations between cardiorespiratory fitness and type 2 diabetes.

Authors: Cai, Lina, Gonzales, Tomas, Wheeler, Eleanor, Kerrison, Nicola D., Day, Felix R., Langenberg, Claudia, Perry, John R. B., Brage, Soren, Wareham, Nicholas J.

Source: Nature Communications; 7/3/2023, Vol. 14 Issue 1, p1-13, 13p

Subject Terms: TYPE 2 diabetes, CARDIOPULMONARY fitness, HEART beat, MYOCARDIUM, EXERCISE tests, PEPTIDES, CARDIOVASCULAR fitness, MUSCLE growth

Geographic Terms: UNITED Kingdom

Descriptive epidemiology of physical activity energy expenditure in UK adults (The Fenland study)

Authors: Lindsay, Tim, Westgate, Kate, Wijndaele, Katrien, Hollidge, Stefanie, Kerrison, Nicola, Forouhi, Nita, Griffin, Simon, Wareham, Nick, Brage, Søren

Source: International journal of behavioral nutrition and physical activity. 16(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192998397.0x000001&indx=1&recIds=ETOCvdc_100192998397.0x000001

Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults.

Authors: Strain, Tessa, Dempsey, Paddy C., Wijndaele, Katrien, Sharp, Stephen J., Kerrison, Nicola, Gonzales, Tomas I., Li, Chunxiao, Wheeler, Eleanor, Langenberg, Claudia, Brage, Søren, Wareham, Nick

Source: Diabetes Care; Jun2023, Vol. 46 Issue 6, p1145-1155, 11p, 1 Chart, 3 Graphs

Divergence of Interdomain Geometry in Two-Domain Proteins

Authors: Han, Jung-Hoon, Kerrison, Nicola, Chothia, Cyrus, Teichmann, Sarah A.

Source: In Structure 2006 14(5):935-945

Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.

Authors: Koprulu, Mine, Zhao, Yajie, Wheeler, Eleanor, Dong, Liang, Rocha, Nuno, Li, Chen, Griffin, John D., Patel, Satish, de Streek, Marcel Van, Glastonbury, Craig A., Stewart, Isobel D., Day, Felix R., Luan, Jian’an, Bowker, Nicholas, Wittemans, Laura B. L., Kerrison, Nicola D., Cai, Lina, Lucarelli, Debora M. E., Barroso, Inês, McCarthy, Mark I.

Source: Journal of Clinical Endocrinology & Metabolism; Apr2022, Vol. 107 Issue 4, p1065-1077, 13p

Proteomic signatures for identification of impaired glucose tolerance

Authors: Carrasco-Zanini, Julia, Pietzner, Maik, Lindbohm, Joni V., Wheeler, Eleanor, Oerton, Erin, Kerrison, Nicola, Simpson, Missy, Westacott, Matthew, Drolet, Dan, Kivimaki, Mika, Ostroff, Rachel, Williams, Stephen A., Wareham, Nicholas J., Langenberg, Claudia

Source: Nature Medicine; November 2022, Vol. 28 Issue: 11 p2293-2300, 8p

Structure, function and evolution of multidomain proteins

Authors: Vogel, Christine, Bashton, Matthew, Kerrison, Nicola D, Chothia, Cyrus, Teichmann, Sarah A

Source: In Current Opinion in Structural Biology 2004 14(2):208-216