Impact of therapeutic doses of prednisolone and other glucocorticoids on insulin secretion from human islets

Authors: Tijani, Omolara Khadijat, Moreno-Lopez, Maria, Louvet, Isaline, Acosta-Montalvo, Ana, Coddeville, Anaïs, Gmyr, Valery, Kerr-Conte, Julie, Pattou, François, Vantyghem, Marie-Christine, Saponaro, Chiara, Bonner, Caroline ^∗∗, Espiard, Stéphanie ^*

Source: In Annales d'Endocrinologie April 2025 86(2)

Islet-after-kidney transplantation versus kidney alone in kidney transplant recipients with type 1 diabetes (KAIAK): a population-based target trial emulation in France

Authors: Armanet, Mathieu, Auxenfans, Céline, Averland, Benoit, Benhamou, Pierre-Yves, Benotmane, Ilies, Berishvili, Ekaterine, Bertrand, Dominique, Blanot, Stéphane, Borot, Sophie, Branchereau, Julien, Broca, Christophe, Brunet, Valérie, Cattan, Pierre, Chaillous, Lucy, Chatauret, Nicolas, Cheisson, Gaelle, Ciacio, Oriana, Colosio, Charlotte, Cornuault, Mathieu, Cuellar, Emmanuel, Defortescu, Guillaume, Defrance, Frédérique, Deshayes, Aurélie, Divard, Gillian, Domet, Thomas, Duffas, Jean-Pierre, Elias, Michelle, Faivre, Lionel, Gaudez, François, Giral, Magali, Girerd, Sophie, Gmyr, Valery, Gouin, Philippe, Gregoire, Hélène, Gueguen, Juliette, Haidar, Fadi, Hubert, Thomas, Janbon, Bénédicte, Jeantet, Marine, Karam, Georges, Kerbaul, François, Kerleau, Clarisse, Kounis, Ilias, Laporte, Caroline, Laurent, Charlotte, Lejay, Anne, Masset, Christophe, Mazeaud, Charles, Mokri, Laëtitia, Moreau, Karine, Morellon, Emmanuel, Muscari, Fabrice, Nasone, Justine, Padilla, Marc, Parier, Bastien, Pastural, Myriam, Perrier, Quentin, Pittau, Gabriella, Prudhomme, Thomas, Renard, Eric, Raverdy, Violeta, Sá Cunha, António, Salloum, Chady, Seizilles De Mazancourt, Emilien, Snanoudj, Renaud, Thaunat, Oliver, Thuret, Rodolphe, Timsit, Marc-Oliver, Vachiery-Lahaye, Florence, Maanaoui, Mehdi ^*, Lenain, Rémi ^*, Foucher, Yohann, Buron, Fanny, Blancho, Gilles, Antoine, Corinne, Caillard, Sophie, Kessler, Laurence, Le Quintrec, Moglie, Villard, Orianne, Anglicheau, Dany, Büchler, Matthias, Brodin-Sartorius, Albane, Frimat, Luc, Malvezzi, Paolo, Lablanche, Sandrine, Badet, Lionel, Esposito, Laure, Chetboun, Mikael, Hamroun, Aghiles, Kerr-Conte, Julie, Berney, Thierry, Vantyghem, Marie-Christine, Hazzan, Marc, Pattou, François ^*

Source: In The Lancet Diabetes & Endocrinology October 2024 12(10):716-724

The concept of immunothrombosis in pancreas transplantation

Authors: Catargi, Bogdan ⁴, Moreau, Karine ⁴, Andres, Axel ⁵, Berishvili, Ekaterine ⁵, Haidar, Fadi ⁵, Wassmer, Charles-Henri ⁵, Benhamou, Pierre Yves ⁶, Lablanche, Sandrine ⁶, Malvezzi, Paolo ⁶, Perrier, Quentin ⁶, Tetaz, Rachel ⁶, Chetboun, Mikael ⁷, Frimat, Marie ⁷, Kerr-Conte, Julie ⁷, Defrance, Frédérique ⁷, Mapihan, Kristell Le ⁷, Maanaoui, Mehdi ⁷, Pattou, François ⁷, Vantyghem, Marie-Christine ⁷, Badet, Lionel ⁸, Berney, Thierry ⁸, Buron, Fanny ⁸, Matillon, Xavier ⁸, Morelon, Emmanuel ⁸, Reffet, Sophie ⁸, Thaunat, Olivier ⁸, Garrigue, Valérie ⁹, Panaro, Fabrizio ⁹, Renard, Eric ⁹, Serre, Jean-Emmanuel ⁹, Blancho, Gilles ¹⁰, Branchereau, Julien ¹⁰, Cantarovich, Diego ¹⁰, Chailloux, Lucy ¹⁰, Masset, Christophe ¹⁰, Mahot-Moreau, Pascale ¹⁰, Mesnard, Benoit ¹⁰, Armanet, Mathieu ¹¹, Cattan, Pierre ¹¹, Ciacio, Oriana ¹¹, Durrbach, Antoine ¹¹, Elias, Michelle ¹¹, Gaudez, François ¹¹, Pittau, Gabriella ¹¹, Riveline, Jean-Pierre ¹¹, Sacunha, Antonio ¹¹, Sartorius, Albane ¹¹, Snanoudj, Renaud ¹¹, Vidal-Trecan, Tiphaine ¹¹, Caillard, Sophie ¹², Kessler, Laurence ¹², Lejay, Anne ¹², Cuellar, Emmanuel ¹³, Duffas, Jean-Pierre ¹³, Esposito, Laure ¹³, Hanaire, Hélène ¹³, Kamar, Nassim ¹³, Prudhomme, Thomas ¹³, Buchler, Mathias ¹⁴, Gueguen, Juliette ¹⁴, Drillaud, Nicolas ³, Ternisien, Catherine ³, Degauque, Nicolas ², Gerard, Nathalie ², Bruneau, Sarah ², Brouard, Sophie ^{1, 2}, Giral, Magali ^{1, 2}, Dantal, Jacques ^{1, 2}

Source: In American Journal of Transplantation November 2024

Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

Authors: Oger, Frédérik, Moreno, Maeva, Derhourhi, Mehdi, Thiroux, Bryan, Berberian, Lionel, Bourouh, Cyril, Durand, Emmanuelle, Amanzougarene, Souhila, Badreddine, Alaa, Blanc, Etienne, Molendi-Coste, Olivier, Pineau, Laurent, Pasquetti, Gianni, Rolland, Laure, Carney, Charlène, Bornaque, Florine, Courty, Emilie, Gheeraert, Céline, Eeckhoute, Jérôme, Dombrowicz, David, Kerr-Conte, Julie, Pattou, François, Staels, Bart, Froguel, Philippe, Bonnefond, Amélie, Annicotte, Jean-Sébastien

Source: In iScience 21 July 2023 26(7)

Association between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective, multicentre, observational cohort study in 1210 patients from the Collaborative Islet Transplant Registry

Authors: Alejandro, R, Aull, M, Bellin, M, Berney, T, Borja-Cacho, D, Brayman, K, Cagliero, E, Caiazzo, R, Cattral, M, Coates, T, Danielson, K, Defrance, F, De Koning, E, Desai, C, Desai, N, Gaber, A O, Gmyr, V, Gores, P, Goss, J A, Gottllieb, P, Greenbaum, C, Hardy, M, Harlan, D, Hering, B, Kandeel, F, Kaufman, D, Kay, T, Keymeulen, B, Khan, K, Kudva, Y, Larsen, C, Le Mapihan, K, Levy, G, Levy, M, Loudovaris, T, Lundgren, T, Maffi, P, Markmann, J, Marks, W H, Naji, A, O'Connell, P, Oberholzer, J, Odorico, J, Onaca, N, Pattou, F, Piemonti, L, Pipeleers, D, Posselt, A, Rajab, A, Raverdy, V, Rickels, M R, Ricordi, C, Rossini, A A, Saudek, F, Schrope, B, Secchi, A, Senior, P, Shapiro, A M J, Shaw, J, Stock, P, Thomas, D, Thompson, M J, Vantyghem, M C, Vargas, L, Wang, H, Wiseman, A, Witkowski, P, Yoon, K, Chetboun, Mikaël, Drumez, Elodie, Ballou, Cassandra, Maanaoui, Mehdi, Payne, Elizabeth, Barton, Franca, Kerr-Conte, Julie, Vantyghem, Marie-Christine, Piemonti, Lorenzo, Rickels, Michael R, Labreuche, Julien, Pattou, François ^*

Source: In The Lancet Diabetes & Endocrinology June 2023 11(6):391-401

Usage des gliflozines dans la maladie rénale chronique

Alternate Title: Use of gliflozins in chronic kidney disease (English)

Authors: Hamdini, Loubna, Defrance, Frederique, Chetboun, Mikael, Kerr-Conte, Julie, Frimat, Marie, Pattou, François, Vantyghem, Marie-Christine, Glowacki, François, Maanaoui, Mehdi

Source: In La Presse Médicale Formation May 2023 4(2):129-134

Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes

Authors: Zubiaga, Lorea ^{1, 10}, Briand, Olivier ^{2, 10}, Auger, Florent ^{3, 10}, Touche, Veronique ², Hubert, Thomas ¹, Thevenet, Julien ¹, Marciniak, Camille ¹, Quenon, Audrey ¹, Bonner, Caroline ^{1, 4}, Peschard, Simon ^{2, 10}, Raverdy, Violeta ¹, Daoudi, Mehdi ¹, Kerr-Conte, Julie ¹, Pasquetti, Gianni ¹, Koepsell, Hermann ⁵, Zdzieblo, Daniela ⁵, Mühlemann, Markus ⁵, Thorens, Bernard ⁶, Delzenne, Nathalie D. ⁷, Bindels, Laure B. ⁷, Deprez, Benoit ⁸, Vantyghem, Marie C. ¹, Laferrère, Blandine ⁹, Staels, Bart ², Huglo, Damien ³, Lestavel, Sophie ², Pattou, François ^{1, 11, ∗}

Source: In iScience 21 April 2023 26(4)

The role of the glucagon‐FGF21 axis in improving beta cell function during glucose intolerance and SGLT2 inhibition.

Authors: Moreno‐Lopez, Maria, Louvet, Isaline, Delalleau, Nathalie, Acosta‐Montalvo, Ana, Thevenet, Julien, Pasquetti, Gianni, Gmyr, Valery, Kerr‐Conte, Julie, Pattou, Francois, Bonner, Caroline, Saponaro, Chiara

Source: Diabetes, Obesity & Metabolism; Feb2025, Vol. 27 Issue 2, p885-898, 14p

Subject Terms: FIBROBLAST growth factors, TYPE 2 diabetes, GLUCOSE intolerance, PANCREATIC beta cells, LIPID metabolism, INSULIN

1921–2021: From insulin discovery to islet transplantation in type 1 diabetes

Alternate Title: 1921–2021 : de la découverte de l’insuline à la greffe d’îlots dans le diabète de type 1 (French)

Authors: Chetboun, Mikael, Jannin, Arnaud, Kerr-Conte, Julie, Pattou, François, Vantyghem, Marie-Christine

Source: In Annales d'Endocrinologie April 2021 82(2):74-77

Pushing the boundaries of organs before it's too late: pre‐emptive regeneration

Authors: Maanaoui, Mehdi, Kerr‐Conte, Julie

Source: Transplant international. 34(10):1761-1769

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131154970.0x000001&indx=1&recIds=ETOCvdc_100131154970.0x000001

REST is a major negative regulator of endocrine differentiation during pancreas organogenesis

Authors: Rovira, Meritxell, Atla, Goutham, Maestro, Miguel Angel, Grau, Vane, García-Hurtado, Javier, Maqueda, Maria, Mosquera, Jose Luis, Yamada, Yasuhiro, Kerr-Conte, Julie, Pattou, Francois

Source: Genes & development. 35(17/18):1229-1242

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627414340&indx=1&recIds=ETOCRN627414340

US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory?

Authors: Piemonti, Lorenzo, Andres, Axel, Casey, John, Koning, Eelco, Engelse, Marten, Hilbrands, Robert, Johnson, Paul, Keymeulen, Bart, Kerr‐Conte, Julie, Korsgren, Olle, Lehmann, Roger, Lundgren, Torbjörn, Maffi, Paola, Pattou, Francois, Saudek, Frantisek, Shaw, James, Scholz, Hanne, White, Steve, Berney, Thierry

Source: Transplant international. 34(7):1182-1186

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124828927.0x000001&indx=1&recIds=ETOCvdc_100124828927.0x000001

Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes.

Authors: Maanaoui, Mehdi, Debillon, Florence, Lenain, Rémi, Defrance, Frédérique, Vantyghem, Marie-Christine, Van Triempont, Marine, Provôt, François, Chetboun, Mikael, Kerr-Conte, Julie, Hamroun, Aghiles, Frimat, Marie, Raverdy, Violeta, Pattou, François, Hazzan, Marc, Glowacki, François

Source: Scientific Reports; 12/30/2024, Vol. 14 Issue 1, p1-10, 10p

Subject Terms: TYPE 2 diabetes, TRANSPLANTATION of organs, tissues, etc., INSULIN resistance, MEDICAL sciences, KIDNEY transplantation, KIDNEYS

PNLIPRP1 Hypermethylation in Exocrine Pancreas Links Type 2 Diabetes and Cholesterol Metabolism.

Authors: Maurin, Lucas, Marselli, Lorella, Boissel, Mathilde, Ning, Lijiao, Boutry, Raphael, Fernandes, Justine, Suleiman, Mara, De Luca, Carmela, Leloire, Audrey, Pascat, Vincent, Toussaint, Bénédicte, Amanzougarene, Souhila, Derhourhi, Mehdi, Jörns, Anne, Lenzen, Sigurd, Pattou, François, Kerr-Conte, Julie, Canouil, Mickaël, Marchetti, Piero, Bonnefond, Amélie

Source: Diabetes; Nov2024, Vol. 73 Issue 11, p1908-1918, 11p

Subject Terms: PANCREATIC diseases, TYPE 2 diabetes, CHOLESTEROL metabolism, LDL cholesterol, GENE expression, GENE enhancers

Shielding islets with human amniotic epithelial cells enhances islet engraftment and revascularization in a murine diabetes model

Authors: Lebreton, Fanny, Bellofatto, Kevin, Wassmer, Charles H., Perez, Lisa, Lavallard, Vanessa, Parnaud, Géraldine, Cottet-Dumoulin, David, Kerr-Conte, Julie, Pattou, François, Bosco, Domenico, Othenin-Girard, Véronique, Martinez de Tejada, Begoña, Berishvili, Ekaterine ^*

Source: In American Journal of Transplantation June 2020 20(6):1551-1561

Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs

Authors: Goutchtat, Rébecca, Quenon, Audrey, Clarisse, Manon, Delalleau, Nathalie, Coddeville, Anaïs, Gobert, Mathilde, Gmyr, Valéry, Kerr‐Conte, Julie, Pattou, François, Hubert, Thomas

Source: Endocrinology, diabetes & metabolism. 6(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187365240.0x000001&indx=1&recIds=ETOCvdc_100187365240.0x000001

Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease

Authors: Raverdy, Violeta, Tavaglione, Federica, Chatelain, Estelle, Lassailly, Guillaume, De Vincentis, Antonio, Vespasiani-Gentilucci, Umberto, Qadri, Sami F., Caiazzo, Robert, Verkindt, Helene, Saponaro, Chiara, Kerr-Conte, Julie, Baud, Gregory, Marciniak, Camille, Chetboun, Mikael, Oukhouya-Daoud, Naima, Blanck, Samuel, Vandel, Jimmy, Olsson, Lisa, Chakaroun, Rima, Gnemmi, Viviane, Leteurtre, Emmanuelle, Lefebvre, Philippe, Haas, Joel T., Yki-Järvinen, Hannele, Francque, Sven, Staels, Bart, Le Roux, Carel W., Tremaroli, Valentina, Mathurin, Philippe, Marot, Guillemette, Romeo, Stefano, Pattou, François

Source: Nature Medicine; December 2024, Vol. 30 Issue: 12 p3624-3633, 10p

Islet-after-kidney transplantation versus kidney alone in kidney transplant recipients with type 1 diabetes (KAIAK): a population-based target trial emulation in France

Authors: Maanaoui, Mehdi, Lenain, Rémi, Foucher, Yohann, Buron, Fanny, Blancho, Gilles, Antoine, Corinne, Caillard, Sophie, Kessler, Laurence, Le Quintrec, Moglie, Villard, Orianne, Anglicheau, Dany, Büchler, Matthias, Brodin-Sartorius, Albane, Frimat, Luc, Malvezzi, Paolo, Lablanche, Sandrine, Badet, Lionel, Esposito, Laure, Chetboun, Mikael, Hamroun, Aghiles, Kerr-Conte, Julie, Berney, Thierry, Vantyghem, Marie-Christine, Hazzan, Marc, Pattou, François, Armanet, Mathieu, Auxenfans, Céline, Averland, Benoit, Benhamou, Pierre-Yves, Benotmane, Ilies, Berishvili, Ekaterine, Bertrand, Dominique, Blanot, Stéphane, Borot, Sophie, Branchereau, Julien, Broca, Christophe, Brunet, Valérie, Cattan, Pierre, Chaillous, Lucy, Chatauret, Nicolas, Cheisson, Gaelle, Ciacio, Oriana, Colosio, Charlotte, Cornuault, Mathieu, Cuellar, Emmanuel, Defortescu, Guillaume, Defrance, Frédérique, Deshayes, Aurélie, Divard, Gillian, Domet, Thomas, Duffas, Jean-Pierre, Elias, Michelle, Faivre, Lionel, Gaudez, François, Giral, Magali, Girerd, Sophie, Gmyr, Valery, Gouin, Philippe, Gregoire, Hélène, Gueguen, Juliette, Haidar, Fadi, Hubert, Thomas, Janbon, Bénédicte, Jeantet, Marine, Karam, Georges, Kerbaul, François, Kerleau, Clarisse, Kounis, Ilias, Laporte, Caroline, Laurent, Charlotte, Lejay, Anne, Masset, Christophe, Mazeaud, Charles, Mokri, Laëtitia, Moreau, Karine, Morellon, Emmanuel, Muscari, Fabrice, Nasone, Justine, Padilla, Marc, Parier, Bastien, Pastural, Myriam, Perrier, Quentin, Pittau, Gabriella, Prudhomme, Thomas, Renard, Eric, Raverdy, Violeta, Sá Cunha, António, Salloum, Chady, Seizilles De Mazancourt, Emilien, Snanoudj, Renaud, Thaunat, Oliver, Thuret, Rodolphe, Timsit, Marc-Oliver, Vachiery-Lahaye, Florence

Source: The Lancet Diabetes & Endocrinology; October 2024, Vol. 12 Issue: 10 p716-724, 9p

Human Fetal Cell Therapy in Huntington's Disease: A Randomized, Multicenter, Phase II Trial

Authors: Bachoud‐Lévi, Anne‐Catherine, Schramm, Catherine, Remy, Philippe, Aubin, Ghislaine, Blond, Serge, Bocket, Laurence, Brugières, Pierre, Calvas, Fabienne, Calvier, Elisabeth, Cassim, François, Challine, Dominique, Gagou, Clarisse Scherer, Langavant, Laurent Cleret, Collier, Francis, Cottencin, Olivier, David, Philippe, Damier, Philippe, Delliaux, Marie, Delmaire, Christine, Delval, Arnaud, Démonet, Jean‐François, Descamps, Philippe, Gaura, Véronique, Gohier, Bénédicte, Goldman, Serge, Haddad, Bassam, Izopet, Jacques, Jeny, Roland, Kerr‐Conte, Julie, Krystowiak, Pierre, Lalanne, Christophe, Lavisse, Sonia, Lefaucheur, Jean‐Pascal, Lemoine, Laurie, Levivier, Marc, Lotterie, Jean‐Albert, Lunel‐Fabiani, Françoise, Maison, Patrick, Massager, Nicolas, Massart, Renaud, Menei, Philippe, Montero‐Menei, Claudia, Neveu, Isabelle, Parant, Olivier, Pautot, Vivien, Payoux, Pierre, Pereon, Yann, Rialland, Amandine, Rosser, Anne, Rouard, Hélène, Schmitz, David, Simonetta‐Moreau, Marion, Simonin, Clémence, Slama, Hichem, Sol, Jean‐Christophe, Supiot, Frédéric, Tanguy, Jean‐Yves, Tenenbaum, Liliane, Verny, Christophe, Youssov, Katia, Peschanski, Marc, Audureau, Etienne, Palfi, Stéphane, Hantraye, Philippe

Source: Movement disorders. 35(8):1323-1335

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107588590.0x000001&indx=1&recIds=ETOCvdc_100107588590.0x000001

A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice

Authors: Demine, Stéphane, Garcia Ribeiro, Rita, Thevenet, Julien, Marselli, Lorella, Marchetti, Piero, Pattou, François, Kerr-Conte, Julie, Devoogdt, Nick, Eizirik, Decio L.

Source: Diabetologia. 63(4):825-836

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164269560.0x000001&indx=1&recIds=ETOCvdc_100164269560.0x000001