Safety and efficacy of pemetrexed for patients with non-small cell lung cancer in the setting of renal impairment: a retrospective study

Authors: Yusuke Shima, Hironori Yoshida, Keiichiro Suminaga, Hiroshi Yoshida, Kentaro Hashimoto, Tatsuya Ogimoto, Kazutaka Hosoya, Hitomi Ajimizu, Tomoko Funazo, Takashi Nomizo, Hiroaki Ozasa, Toyohiro Hirai

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-11 (2025)

Subject Terms: Pemetrexed, Non-small cell lung cancer, Safety and efficacy, Renal impairment, Creatinine clearance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/544bb5aa3b984b30b7c504f9dd5c5251

Artificial intelligence-based analysis of the spatial distribution of abnormal computed tomography patterns in SARS-CoV-2 pneumonia: association with disease severity

Authors: Yusuke Kataoka, Naoya Tanabe, Masahiro Shirata, Nobuyoshi Hamao, Issei Oi, Tomoki Maetani, Yusuke Shiraishi, Kentaro Hashimoto, Masatoshi Yamazoe, Hiroshi Shima, Hitomi Ajimizu, Tsuyoshi Oguma, Masahito Emura, Kazuo Endo, Yoshinori Hasegawa, Tadashi Mio, Tetsuhiro Shiota, Hiroaki Yasui, Hitoshi Nakaji, Michiko Tsuchiya, Keisuke Tomii, Toyohiro Hirai, Isao Ito

Source: Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)

Subject Terms: COVID-19, Pneumonia, Quantitative analysis, Ground glass opacity, Peripheral area, Central area, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/dcd0d6febee64d4f9c3eff8fa47c24fd

Hydraulic calcium silicate-based root canal sealers mitigate proinflammatory cytokine synthesis and promote osteogenesis in vitro

Authors: Aseel Alchawoosh, Kentaro Hashimoto, Nobuyuki Kawashima, Sonoko Noda, Kosuke Nozaki, Takashi Okiji

Source: Journal of Dental Sciences, Vol 18, Iss 4, Pp 1731-1739 (2023)

Subject Terms: Cytokine, Differentiation, Endodontic obturation, Macrophage, Osteoblast, Calcium signaling, Dentistry, RK1-715

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S199179022200349X; https://doaj.org/toc/1991-7902

Access URL: https://doaj.org/article/08a289faaf5548f48686c443b1109e09

Detection of a co-mutation in the epidermal growth factor receptor gene exon 20 H773L/V774M by FoundationOne test and treatment with osimertinib: A case report

Authors: Hiroshi Yoshida, Hiroaki Ozasa, Kentaro Hashimoto, Yusuke Shima, Keiichiro Suminaga, Hitomi Ajimizu, Takashi Nomizo, Hironori Yoshida, Masahiro Yoshioka, Masashi Kanai, Takehito Shukuya, Manabu Muto, Toyohiro Hirai

Source: Current Problems in Cancer: Case Reports, Vol 14, Iss , Pp 100286- (2024)

Subject Terms: EGFR mutation, Next-geneneration sequencing, Non-small cell lung cancer, EGFR tyrosine kinase inhibitor, Treatment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666621924000097; https://doaj.org/toc/2666-6219

Access URL: https://doaj.org/article/9c163bc24b6e4a9181dc97cc3c256896

Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy‐induced colitis

Authors: Toshiharu Sakurai, Marco A De Velasco, Kazuko Sakai, Tomoyuki Nagai, Hiroki Nishiyama, Kentaro Hashimoto, Hirotsugu Uemura, Hisato Kawakami, Kazuhiko Nakagawa, Hiroyuki Ogata, Kazuto Nishio, Masatoshi Kudo

Source: Molecular Oncology, Vol 16, Iss 7, Pp 1493-1507 (2022)

Subject Terms: Enterobacteriaceae, gastrointestinal immune‐related adverse event, immune checkpoint, integrative analysis, microbiome, whole transcriptome, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/d953bfb730bd47ca942694545bf5a7ad

Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro

Authors: Thoai Quoc Kieu, Kento Tazawa, Nobuyuki Kawashima, Sonoko Noda, Mayuko Fujii, Keisuke Nara, Kentaro Hashimoto, Peifeng Han, Takashi Okiji

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e785b702e5b54909a4293f239fa80d98

Hypoxia-inducible factor 1α induces osteo/odontoblast differentiation of human dental pulp stem cells via Wnt/β-catenin transcriptional cofactor BCL9

Authors: Shion Orikasa, Nobuyuki Kawashima, Kento Tazawa, Kentaro Hashimoto, Keisuke Sunada-Nara, Sonoko Noda, Mayuko Fujii, Tetsu Akiyama, Takashi Okiji

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/414bc6540fbb49f5a730bc042ccaddc8

Two-directional range sensor device using direction converter of laser beam

Authors: Kentaro HASHIMOTO, Daisuke SEKIMORI

Source: Nihon Kikai Gakkai ronbunshu, Vol 83, Iss 855, Pp 17-00117-17-00117 (2017)

Subject Terms: range sensor, laser beam, acrylic prisms, direction converter, Mechanical engineering and machinery, TJ1-1570, Engineering machinery, tools, and implements, TA213-215

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/transjsme/83/855/83_17-00117/_pdf/-char/en; https://doaj.org/toc/2187-9761

Access URL: https://doaj.org/article/ab1aed4c1a434c5fb3996151e9956803

Coupling of Cortical Hyperintense Signals and Increased Glucose Metabolism in a Case of Anti-GABAA Receptor Antibody-associated Encephalitis.

Authors: Kentaro Hashimoto, Takumi Nakamura, Yukio Fujita, Minori Furuta, Kouki Makioka, Yuki Shimoda, Takahiro Iizuka, Yoshio Ikeda

Source: Internal Medicine; 2023, Vol. 62 Issue 23, p3545-3548, 4p

CD47 polymorphism for predicting nivolumab benefit in patients with advanced non-small-cell lung cancer.

Authors: TATSUYA OGIMOTO, HIROAKI OZASA, HIRONORI YOSHIDA, TAKASHI NOMIZO, TOMOKO FUNAZO, HIROSHI YOSHIDA, KENTARO HASHIMOTO, KAZUTAKA HOSOYA, MASATOSHI YAMAZOE, HITOMI AJIMIZU, TAKAHIRO TSUJI, YUICHI SAKAMORI, KIYOMITSU KUNINAGA, SATOSHI MORITA, TOYOHIRO HIRAI

Source: Oncology Letters; Aug2023, Vol. 26 Issue 2, p1-7, 7p

Subject Terms: NON-small-cell lung carcinoma, CD47 antigen, NIVOLUMAB, SINGLE nucleotide polymorphisms, IMMUNE checkpoint inhibitors

Company/Entity: KYOTO Daigaku

Evaluation of the anti-inflammatory effects of surface-reaction-type pre-reacted glass-ionomer filler containing root canal sealer in lipopolysaccharide-stimulated RAW264.7 macrophages.

Authors: Htoo Shwe Sin THEIN, Kentaro HASHIMOTO, Nobuyuki KAWASHIMA, Sonoko NODA, Takashi OKIJI

Source: Dental Materials Journal; 2022, Vol. 41 Issue 1, p150-158, 9p

Subject Terms: PIT & fissure sealants (Dentistry), NF-kappa B, PLANT extracts, CURCUMIN, MACROPHAGES, METAL ions, HEAVY metals

Evaluation of the cytocompatibility of methacrylate resin-based root canal sealers with osteoblast-like cells.

Authors: Yadanar Su PHYO, Kentaro HASHIMOTO, Nobuyuki KAWASHIMA, Masashi KURAMOTO, Takashi OKIJI

Source: Dental Materials Journal; 2021, Vol. 40 Issue 4, p942-948, 7p

Subject Terms: DENTAL pulp cavities, METHACRYLATES, COMMERCIAL products, CELL growth, CELL culture, SCANNING electron microscopy, UREA-formaldehyde resins

Successful oral desensitization with crizotinib after crizotinib-induced hepatitis in an anaplastic lymphoma kinase-rearranged non-small-cell lung cancer patient: A case report.

Authors: YUTO YASUDA, YASUYO NISHIKAWA, YUICHI SAKAMORI, MAKOTO TERAO, KENTARO HASHIMOTO, TOMOKO FUNAZO, TAKASHI NOMIZO, TAKAHIRO TSUJI, HIRONORI YOSHIDA, HIROKI NAGAI, HIROAKI OZASA, TOYOHIRO HIRAI, YOUNG HAK KIM

Source: Molecular & Clinical Oncology; 2017, Vol. 7 Issue 2, p295-297, 3p

Subject Terms: DESENSITIZATION (Psychotherapy), ANAPLASTIC lymphoma kinase, CRIZOTINIB

Fermi-level pinning at metal/4H-SiC contact induced by SiC x O y interlayer.

Authors: Kentaro Hashimoto, Takuma Doi, Shigehisa Shibayama, Osamu Nakatsuka

Source: Japanese Journal of Applied Physics; Apr2020, Vol. 59 Issue SG, p1-1, 1p

Drug approval in Japan questioned.

Authors: Keiji Hayashi¹ (AUTHOR), Kentaro Hashimoto² (AUTHOR), Motokazu Yanagi³ (AUTHOR), Tadanori Umeda⁴ (AUTHOR), Rokuro Hama⁵ (AUTHOR)

Source: Lancet. 8/8/1998, Vol. 352 Issue 9126, p491-491. 1/2p.