Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in MiceSummary

Authors: Kyo Sasaki, Sohji Nishina, Akira Yamauchi, Kotaro Fukuda, Yuichi Hara, Masahiro Yamamura, Kensuke Egashira, Keisuke Hino

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 739-762 (2021)

Subject Terms: PLGA, IFN-γ, Lactate, Chemokine, Programmed Death 1, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X20301739; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/bd4510dde3884a1182d2c772befeec9f

Simultaneous targeting of mitochondria and monocytes enhances neuroprotection against ischemia–reperfusion injury

Authors: Arihide Okahara, Jun-ichiro Koga, Tetsuya Matoba, Masaki Fujiwara, Masaki Tokutome, Gentaro Ikeda, Kaku Nakano, Masaki Tachibana, Tetsuro Ago, Takanari Kitazono, Hiroyuki Tsutsui, Kensuke Egashira

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/929409dd3f8a48648a7dd82691a4b1ce

Nanoparticle‐Mediated Simultaneous Targeting of Mitochondrial Injury and Inflammation Attenuates Myocardial Ischemia‐Reperfusion Injury

Authors: Gentaro Ikeda, Tetsuya Matoba, Ayako Ishikita, Kazuhiro Nagaoka, Kaku Nakano, Jun‐ichiro Koga, Hiroyuki Tsutsui, Kensuke Egashira

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 12 (2021)

Subject Terms: cardioprotection, drug delivery system, ischemia‐reperfusion injury, nanotechnology, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/da210d10d67e4303b06574fa0d6e1404

Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of γ-oryzanol on fuel dyshomeostasis in genetically obese-diabetic ob/ob mice

Authors: Chisayo Kozuka, Chigusa Shimizu-Okabe, Chitoshi Takayama, Kaku Nakano, Hidetaka Morinaga, Ayano Kinjo, Kotaro Fukuda, Asuka Kamei, Akihito Yasuoka, Takashi Kondo, Keiko Abe, Kensuke Egashira, Hiroaki Masuzaki

Source: Drug Delivery, Vol 24, Iss 1, Pp 558-568 (2017)

Subject Terms: type 2 diabetes mellitus, brown rice, γ-oryzanol, nanotechnology, poly (dl-lactide-co-glycolide), obesity, therapeutic modality, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/8b4813d137704330bf54da9b7008609d

Anti-inflammatory Nanomedicine for Cardiovascular Disease

Authors: Shunsuke Katsuki, Tetsuya Matoba, Jun-ichiro Koga, Kaku Nakano, Kensuke Egashira

Source: Frontiers in Cardiovascular Medicine, Vol 4 (2017)

Subject Terms: coronary artery disease, inflammation, nanomedicine, monocytes, macrophages, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fcvm.2017.00087/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/4cca780f31744bc7bfe8fc81939bb2b1

BubR1 Insufficiency Results in Decreased Macrophage Proliferation and Attenuated Atherogenesis in Apolipoprotein E‐Deficient Mice

Authors: Shinichi Tanaka, Takuya Matsumoto, Yutaka Matsubara, Yui Harada, Ryoichi Kyuragi, Jun‐ichiro Koga, Kensuke Egashira, Yutaka Nakashima, Yoshikazu Yonemitsu, Yoshihiko Maehara

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 9, Pp n/a-n/a (2016)

Subject Terms: atherosclerosis, cell cycle, macrophage, proliferation, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/af8facb1c85046a09a9dbac1da2991bf

Nanoparticle‐Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia‐Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction

Authors: Ayako Ishikita, Tetsuya Matoba, Gentaro Ikeda, Jun‐ichiro Koga, Yajing Mao, Kaku Nakano, Osamu Takeuchi, Junichi Sadoshima, Kensuke Egashira

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)

Subject Terms: drug delivery system, ischemia‐reperfusion injury, mitochondria, myocardial infarction, nanoparticle, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/540cfb1c5d594d74831ba051be52bcf2

A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model.

Authors: Kenzo Ichimura, Tetsuya Matoba, Kaku Nakano, Masaki Tokutome, Katsuya Honda, Jun-Ichiro Koga, Kensuke Egashira

Source: PLoS ONE, Vol 11, Iss 9, p e0162425 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5014419?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6044c3a1866e4608bf0a6c539f8fa98e

Stress and Vascular Responses: Anti-inflammatory Therapeutic Strategy Against Atherosclerosis and Restenosis After Coronary Intervention

Authors: Shiro Kitamoto, Kensuke Egashira, Akira Takeshita

Source: Journal of Pharmacological Sciences, Vol 91, Iss 3, Pp 192-196 (2003)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319327331; https://doaj.org/toc/1347-8613

Access URL: https://doaj.org/article/1b55a473404e42f496fb89c2e06ec907

A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model.

Authors: Kazuhiro Nagaoka, Tetsuya Matoba, Yajing Mao, Yasuhiro Nakano, Gentaro Ikeda, Shizuka Egusa, Masaki Tokutome, Ryoji Nagahama, Kaku Nakano, Kenji Sunagawa, Kensuke Egashira

Source: PLoS ONE, Vol 10, Iss 7, p e0132451 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4500569?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3dd4165dd0b346f7bddb3d82747d3ea0

Lipid-Lowering Therapy With Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion: A Role of Serum Oxysterols.

Authors: Katsuya Honda, Tetsuya Matoba, Yoshibumi Antoku, Jun-ichiro Koga, Ikuyo Ichi, Kaku Nakano, Hiroyuki Tsutsui, Kensuke Egashira

Source: Arteriosclerosis, Thrombosis & Vascular Biology; Apr2018, Vol. 38 Issue 4, p757-771, 15p, 2 Charts, 6 Graphs

Intratracheal Administration of Prostacyclin Analogue-incorporated Nanoparticles Ameliorates the Development of Monocrotaline and Sugen-Hypoxia-induced Pulmonary Arterial Hypertension.

Authors: Satoshi Akagi, Kazufumi Nakamura, Hiromi Matsubara, Megumi Kondo, Daiji Miura, Tetsuya Matoba, Kensuke Egashira, Hiroshi Ito

Source: Journal of Cardiovascular Pharmacology; Apr2016, Vol. 67 Issue 4, p290-298, 9p

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.

Authors: Akihiro Shirakabe, Peiyong Zhai, Yoshiyuki Ikeda, Toshiro Saito, Yasuhiro Maejima, Chiao-Po Hsu, Masatoshi Nomura, Kensuke Egashira, Beth Levine, Junichi Sadoshima, Shirakabe, Akihiro, Zhai, Peiyong, Ikeda, Yoshiyuki, Saito, Toshiro, Maejima, Yasuhiro, Hsu, Chiao-Po, Nomura, Masatoshi, Egashira, Kensuke, Levine, Beth, Sadoshima, Junichi

Source: Circulation; 3/29/2016, Vol. 133 Issue 13, p1249-1263, 15p

Pioglitazone-Incorporated Nanoparticles Prevent Plaque Destabilization and Rupture by Regulating Monocyte/Macrophage Differentiation in ApoE^-/- Mice.

Authors: Soichi Nakashiro, Tetsuya Matoba, Ryuta Umezu, Jun-ichiro Koga, Masaki Tokutome, Shunsuke Katsuki, Kaku Nakano, Kenji Sunagawa, Kensuke Egashira

Source: Arteriosclerosis, Thrombosis & Vascular Biology; Mar2016, Vol. 36 Issue 3, p491-500, 10p

Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress.

Authors: Yoshiyuki Ikeda, Akihiro Shirakabe, Yasuhiro Maejima, Peiyong Zhai, Sciarretta, Sebastiano, Toli, Jessica, Masatoshi Nomura, Katsuyoshi Mihara, Kensuke Egashira, Mitsuru Ohishi, Maha Abdellatif, Junichi Sadoshima

Source: Circulation Research; 1/16/2015, Vol. 116 Issue 2, p264-278, 15p

Suppression of wear-particle-induced pro-inflammatory cytokine and chemokine production in macrophages via NF-κB decoy oligodeoxynucleotide: A preliminary report.

Authors: Tzu-hua Lin, Zhenyu Yao, Taishi Sato, Keeney, Michael, Chenguang Li, Pajarinen, Jukka, Fan Yang, Kensuke Egashira, Goodman, Stuart B.

Source: Acta Biomaterialia; Aug2014, Vol. 10 Issue 8, p3747-3755, 9p

Subject Terms: CYTOKINES, CHEMOKINES, MACROPHAGES, NF-kappa B, ARTIFICIAL joints, COST effectiveness

Nanoparticle-Mediated Delivery of Pitavastatin Inhibits Atherosclerotic Plaque Destabilization/Rupture in Mice by Regulating the Recruitment of Inflammatory Monocytes.

Authors: Shunsuke Katsuki, Tetsuya Matoba, Soichi Nakashiro, Kei Sato, Jun-ichiro Koga, Kaku Nakano, Yasuhiro Nakano, Shizuka Egusa, Kenji Sunagawa, Kensuke Egashira

Source: Circulation; 2/25/2014, Vol. 129 Issue 8, p896-906, 11p

Monocyte chemoattractant protein–1 increases microglial infiltration and aggressiveness of gliomas.

Authors: Michael Platten, Alexandra Kretz, Ulrike Naumann, Steffen Aulwurm, Kensuke Egashira, Stefan Isenmann, Michael Weller

Source: Annals of Neurology; Sep2003, Vol. 54 Issue 3, p388-392, 5p

ATP-sensitive K⁺ channel opener pinacidil augments β1-adrenoceptor-induced coronary vasodilation in dogs.

Authors: YOUSUKE KATSUDA, KENSUKE EGASHIRA, HIDEKI UENO, YUKINORI ARAI, YUTAKA AKATSUKA, TAKESHI KUGA, HIROAKI SHIMOKAWA, AKIRA TAKESHITA

Source: American Journal of Physiology: Heart & Circulatory Physiology; Jun1996, Vol. 270 Issue 6, pH2210-H2215, 6p

Glibenclamide prevents coronary vasodilation induced by β1-adrenoceptor stimulation in dogs.

Authors: TAKAHIRO NARISHIGE, KENSUKE EGASHIRA, YUTAKA AKATSUKA, YOSHIHIRO IMAMURA, TEISUKE TAKAHASHI, HIROMITSU KASUYA, AKIRA TAKESHITA

Source: American Journal of Physiology: Heart & Circulatory Physiology; 1994, Vol. 266 Issue 1, pH84-H92, 9p