Translational regulation and protein-coding capacity of the 5′ untranslated region of human TREM2

Authors: Motoaki Yanaizu, Haruka Adachi, Makoto Araki, Kenji Kontani, Yoshihiro Kino

Source: Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/6f324197007345029d78ef879632029f

Caenorhabditis elegans PTR/PTCHD PTR-18 promotes the clearance of extracellular hedgehog-related protein via endocytosis.

Authors: Hirohisa Chiyoda, Masahiko Kume, Carla Cadena Del Castillo, Kenji Kontani, Anne Spang, Toshiaki Katada, Masamitsu Fukuyama

Source: PLoS Genetics, Vol 17, Iss 4, p e1009457 (2021)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/b0a9882bbb8243e784ddc8c6ac1a01e3

TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells

Authors: Shin-Ichiroh Saitoh, Fumiko Abe, Atsuo Kanno, Natsuko Tanimura, Yoshiko Mori Saitoh, Ryutaro Fukui, Takuma Shibata, Katsuaki Sato, Takeshi Ichinohe, Mayumi Hayashi, Kazuishi Kubota, Hiroko Kozuka-Hata, Masaaki Oyama, Yorifumi Kikko, Toshiaki Katada, Kenji Kontani, Kensuke Miyake

Source: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f3a96501c2b548c493e42bf4711580c2

C. elegans AMPKs promote survival and arrest germline development during nutrient stress

Authors: Masamitsu Fukuyama, Kensuke Sakuma, Riyong Park, Hidefumi Kasuga, Ryotaro Nagaya, Yuriko Atsumi, Yumi Shimomura, Shinya Takahashi, Hiroaki Kajiho, Ann Rougvie, Kenji Kontani, Toshiaki Katada

Source: Biology Open, Vol 1, Iss 10, Pp 929-936 (2012)

Subject Terms: AMPK, Stem cell, Diapause, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://bio.biologists.org/content/1/10/929; https://doaj.org/toc/2046-6390

Access URL: https://doaj.org/article/7f91c3d7b9d5460a8724a09f5751566c

Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain.

Authors: Sebiha Cevik, Anna A W M Sanders, Erwin Van Wijk, Karsten Boldt, Lara Clarke, Jeroen van Reeuwijk, Yuji Hori, Nicola Horn, Lisette Hetterschijt, Anita Wdowicz, Andrea Mullins, Katarzyna Kida, Oktay I Kaplan, Sylvia E C van Beersum, Ka Man Wu, Stef J F Letteboer, Dorus A Mans, Toshiaki Katada, Kenji Kontani, Marius Ueffing, Ronald Roepman, Hannie Kremer, Oliver E Blacque

Source: PLoS Genetics, Vol 9, Iss 12, p e1003977 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3854969?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/566785b284434b95974086b530bbc77f

RINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odin.

Authors: Hiroaki Kajiho, Shinichi Fukushima, Kenji Kontani, Toshiaki Katada

Source: PLoS ONE, Vol 7, Iss 1, p e30575 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3264577?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0bc22db885bd48ea878b397060c7b149

Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1.

Authors: Yuki Toyama^1,2, Kenji Kontani³, Toshiaki Katada⁴, Ichio Shimada¹ shimada@iw-nmr.f.u-tokyo.ac.jp

Source: Science Advances. Aug2019, Vol. 5 Issue 8, p1-9. 9p.

GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.

Authors: Hikaru Shimizu, Sachiko Toma-Fukai, Kenji Kontani, Toshiaki Katada, Toshiyuki Shimizu

Source: Proceedings of the National Academy of Sciences of the United States of America; 9/18/2018, Vol. 115 Issue 38, p9563-9568, 6p

Subject Terms: RHO GTPases, GUANOSINE triphosphatase, GUANINE nucleotide exchange factors, MOLECULAR chaperones, CRYSTAL structure

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos.

Authors: Miho Oka, Keisuke Hashimoto, Yoshifumi Yamaguchi, Shin-Ichiro Saitoh, Yuki Sugiura, Yuji Motoi, Kurara Honda, Yorifumi Kikko, Shinya Ohata, Makoto Suematsu, Masayuki Miura, Kensuke Miyake, Toshiaki Katada, Kenji Kontani

Source: Journal of Cell Science; 10/15/2017, Vol. 130 Issue 20, p3568-3577, 10p

Subject Terms: LYSOSOMES, BIODEGRADATION, YOLK sac, ENDODERM, PROTEOLYSIS, EMBRYOS, GUANOSINE triphosphatase

Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.

Authors: Shohei Nozaki, Yohei Katoh, Masaya Terada, Saki Michisaka, Teruki Funabashi, Senye Takahashi, Kazuhisa Nakayama, Kenji Kontani

Source: Journal of Cell Science; 2/1/2017, Vol. 130 Issue 3, p563-576, 14p

Subject Terms: JOUBERT syndrome, ADP-ribosylation factors, GUANOSINE triphosphatase

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

Authors: Yasunobu Nagata¹, Kenji Kontani², Terukazu Enami³, Keisuke Kataoka¹, Ryohei Ishii⁴, Yasushi Totoki⁵, Kataoka, Tatsuki R.⁶, Masahiro Hirata⁶, Kazuhiro Aoki⁷, Kazumi Nakano⁸, Akira Kitanaka⁹, Mamiko Sakata-Yanagimoto³, Sachiko Egami², Yuichi Shiraishi¹⁰, Kenichi Chiba¹⁰, Hiroko Tanaka¹¹, Yusuke Shiozawa¹, Tetsuichi Yoshizato¹, Hiromichi Suzuki¹, Ayana Kon¹

Source: Blood. 2/4/2016, Vol. 127 Issue 5, p596-604. 9p.

Subject Terms: *RAS oncogenes, *ADULT T-cell leukemia, *DNA mutational analysis, *HTLV-I, *GUANOSINE triphosphate, *NUCLEOTIDE sequencing

Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export.

Authors: Kota Saito¹, ksaito@mol.f.u-tokyo.ac.jp, Koh Yamashiro¹, Noriko Shimazu¹, Tomoya Tanabe¹, Kenji Kontani¹, Toshiaki Katada¹

Source: Journal of Cell Biology; 9/15/2014, Vol. 206 Issue 6, p751-762, 12p

Calmodulin enhances mTORC1 signaling by preventing TSC2-Rheb binding.

Authors: Yuna Amemiya¹, Yuichiro Ioi¹, Makoto Araki², Kenji Kontani², Masatoshi Maki¹, Hideki Shibata¹, Terunao Takahara¹ takahara@agr.nagoya-u.ac.jp

Source: Journal of Biological Chemistry. Feb2025, Vol. 301 Issue 2, p1-16. 16p.

Subject Terms: *CALCIUM ions, *TUBEROUS sclerosis, *INTRACELLULAR calcium, *BINDING site assay, *CELL growth

Tyrosine Phosphorylation of the c-cblProto-oncogene Product Mediated by Cell Surface Antigen CD38 in HL-60 Cells(∗)

Authors: Kenji, Kontani, Kukimoto, Iwao, Nishina, Hiroshi, Hoshino, Shin-ichi, Hazeki, Osamu, Kanaho, Yasunori, Katada, Toshiaki

Source: Journal of Biological Chemistry; January 1996, Vol. 271 Issue: 3 p1534-1537, 4p

Tyrosine Phosphorylation of the c-cbl Proto-oncogene Product Mediated by Cell Surface Antigen CD38 in HL-60 Cells

Authors: Kenji, Kontani, Kukimoto, Iwao, Nishina, Hiroshi, Hoshino, Shin-ichi, Hazeki, Osamu, Kanaho, Yasunori, Katada, Toshiaki

Source: In Journal of Biological Chemistry 19 January 1996 271(3):1534-1537

Development of a versatile HPLC-based method to evaluate the activation status of small GTPases.

Authors: Makoto Araki¹, Kaho Yoshimoto¹, Meguri Ohta¹, Toshiaki Katada², Kenji Kontani¹ kontani@my-pharm.ac.jp

Source: Journal of Biological Chemistry. Dec2021, Vol. 297 Issue 6, p1-10. 10p.

Subject Terms: *GTPASE-activating protein, *GUANOSINE triphosphatase, *CELL physiology, *CELL proliferation, *GUANOSINE triphosphate, *GUANINE

Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.

Authors: Hikaru Shimizu¹, Sachiko Toma-Fukai¹, Shinya Saijo², Nobutaka Shimizu², Kenji Kontani³, Toshiaki Katada¹, Toshiyuki Shimizu¹ shimizu@mol.f.u-tokyo.ac.jp

Source: Journal of Biological Chemistry. 8/11/2017, Vol. 292 Issue 32, p13441-13448. 8p.

Subject Terms: *GUANINE nucleotide exchange factors, *MOLECULAR chaperones, *ISOPRENYLATION, *CHROMATOGRAPHIC analysis, *SURFACE plasmon resonance

Di-Ras2 Protein Forms a Complex with SmgGDS Protein in Brain Cytosol in Order to Be in a Low Affinity State for Guanine Nucleotides.

Authors: Yoshitaka Ogita¹, Sachiko Egami¹, Ebihara, Arisa¹, Ueda, Nami¹, Toshiaki Katada¹, Kenji Kontani¹ kontani@my-pharm.ac.jp

Source: Journal of Biological Chemistry. 8/14/2015, Vol. 290 Issue 33, p20245-20256. 12p.

Subject Terms: *PROTEIN research, *CYTOSOL, *GUANOSINE triphosphatase, *NUCLEOTIDES, *BIOCHEMICAL research