Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization

Authors: Zheng, Jie, Wheeler, Eleanor, Pietzner, Maik, Andlauer, Till F. M., Yau, Michelle S., Hartley, April E., Brumpton, Ben Michael, Rasheed, Humaira, Kemp, John P., Frysz, Monika, Robinson, Jamie, Reppe, Sjur, Prijatelj, Vid, Gautvik, Kaare M., Falk, Louise, Maerz, Winfried, Gergei, Ingrid, Peyser, Patricia A., Kavousi, Maryam, Vries, Paul S., Miller, Clint L., Bos, Maxime, Laan, Sander W., Malhotra, Rajeev, Herrmann, Markus, Scharnagl, Hubert, Kleber, Marcus, Dedoussis, George, Zeggini, Eleftheria, Nethander, Maria, Ohlsson, Claes, Lorentzon, Mattias, Wareham, Nick, Langenberg, Claudia, Holmes, Michael V., Davey Smith, George, Tobias, Jonathan H.

Source: Arthritis & rheumatology. 75(10):1781-1792

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194539639.0x000001&indx=1&recIds=ETOCvdc_100194539639.0x000001

A Genome‐Wide Association Study Meta‐Analysis of Alpha Angle Suggests Cam‐Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults

Authors: Faber, Benjamin G., Frysz, Monika, Hartley, April E., Ebsim, Raja, Boer, Cindy G., Saunders, Fiona R., Gregory, Jennifer S., Aspden, Richard M., Harvey, Nicholas C., Southam, Lorraine, Giles, William, Le Maitre, Christine L., Wilkinson, J. Mark, Meurs, Joyce B. J., Zeggini, Eleftheria, Cootes, Timothy, Lindner, Claudia, Kemp, John P., Davey Smith, George, Tobias, Jonathan H.

Source: Arthritis & rheumatology. 75(6):900-909

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184493691.0x000001&indx=1&recIds=ETOCvdc_100184493691.0x000001

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses

Authors: Faber, Benjamin G., Frysz, Monika, Boer, Cindy G., Evans, Daniel S., Ebsim, Raja, Flynn, Kaitlyn A., Lundberg, Mischa, Southam, Lorraine, Hartley, April, Saunders, Fiona R., Lindner, Claudia, Gregory, Jennifer S., Aspden, Richard M., Lane, Nancy E., Harvey, Nicholas C., Evans, David M., Zeggini, Eleftheria, Davey Smith, George, Cootes, Timothy, Van Meurs, Joyce, Kemp, John P., Tobias, Jonathan H.

Source: In eBioMedicine September 2023 95

The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture.

Authors: Faber, Benjamin G, Frysz, Monika, Zheng, Jaiyi, Lin, Huandong, Flynn, Kaitlyn A, Ebsim, Raja, Saunders, Fiona R, Beynon, Rhona, Gregory, Jennifer S, Aspden, Richard M, Harvey, Nicholas C, Lindner, Claudia, Cootes, Timothy, Evans, David M, Smith, George Davey, Gao, Xin, Wang, Sijia, Kemp, John P, Tobias, Jonathan H

Source: Human Molecular Genetics; Feb2025, Vol. 34 Issue 3, p207-217, 11p

Limb development genes underlie variation in human fingerprint patterns

Authors: Li, Jinxi, Glover, James D., Zhang, Haiguo, Peng, Meifang, Tan, Jingze, Mallick, Chandana Basu, Hou, Dan, Yang, Yajun, Wu, Sijie, Liu, Yu, Peng, Qianqian, Zheng, Shijie C., Crosse, Edie I., Medvinsky, Alexander, Anderson, Richard A., Brown, Helen, Yuan, Ziyu, Zhou, Shen, Xu, Yanqing, Kemp, John P., Ho, Yvonne Y.W., Loesch, Danuta Z., Wang, Lizhong, Li, Yingxiang, Tang, Senwei, Wu, Xiaoli, Walters, Robin G., Lin, Kuang, Meng, Ruogu, Lv, Jun, Chernus, Jonathan M., Neiswanger, Katherine, Feingold, Eleanor, Evans, David M., Medland, Sarah E., Martin, Nicholas G., Weinberg, Seth M., Marazita, Mary L., Chen, Gang, Chen, Zhengming, Zhou, Yong, Cheeseman, Michael, Wang, Lan, Jin, Li, Headon, Denis J., Wang, Sijia

Source: In Cell 6 January 2022 185(1):95-112

Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

Authors: McDonald, Michelle M., Khoo, Weng Hua, Ng, Pei Ying, Xiao, Ya, Zamerli, Jad, Thatcher, Peter, Kyaw, Wunna, Pathmanandavel, Karrnan, Grootveld, Abigail K., Moran, Imogen, Butt, Danyal, Nguyen, Akira, Corr, Alexander, Warren, Sean, Biro, Maté, Butterfield, Natalie C., Guilfoyle, Siobhan E., Komla-Ebri, Davide, Dack, Michael R.G., Dewhurst, Hannah F., Logan, John G., Li, Yongxiao, Mohanty, Sindhu T., Byrne, Niall, Terry, Rachael L., Simic, Marija K., Chai, Ryan, Quinn, Julian M.W., Youlten, Scott E., Pettitt, Jessica A., Abi-Hanna, David, Jain, Rohit, Weninger, Wolfgang, Lundberg, Mischa, Sun, Shuting, Ebetino, Frank H., Timpson, Paul, Lee, Woei Ming, Baldock, Paul A., Rogers, Michael J., Brink, Robert, Williams, Graham R., Bassett, J.H. Duncan, Kemp, John P., Pavlos, Nathan J., Croucher, Peter I., Phan, Tri Giang

Source: In Cell 4 March 2021 184(5):1330-1347

Genome-wide association study of circulating interleukin 6 levels identifies novel loci

Authors: Ahluwalia, Tarunveer S, Prins, Bram P, Abdollahi, Mohammadreza, Armstrong, Nicola J, Aslibekyan, Stella, Bain, Lisa, Jefferis, Barbara, Baumert, Jens, Beekman, Marian, Ben-Shlomo, Yoav, Bis, Joshua C, Mitchell, Braxton D, de Geus, Eco, Delgado, Graciela E, Marek, Diana, Eriksson, Joel, Kajantie, Eero, Kanoni, Stavroula, Kemp, John P, Lu, Chen, Marioni, Riccardo E, McLachlan, Stela, Milaneschi, Yuri, Nolte, Ilja M, Petrelis, Alexandros M, Porcu, Eleonora, Sabater-Lleal, Maria, Naderi, Elnaz, Seppälä, Ilkka, Shah, Tina, Singhal, Gaurav, Standl, Marie, Teumer, Alexander, Thalamuthu, Anbupalam, Thiering, Elisabeth, Trompet, Stella, Ballantyne, Christie M, Benjamin, Emelia J, Casas, Juan P, Toben, Catherine, Dedoussis, George, Deelen, Joris, Durda, Peter, Engmann, Jorgen, Feitosa, Mary F, Grallert, Harald, Hammarstedt, Ann, Harris, Sarah E, Homuth, Georg, Hottenga, Jouke-Jan, Jalkanen, Sirpa, Jamshidi, Yalda, Jawahar, Magdalene C, Jess, Tine, Kivimaki, Mika, Kleber, Marcus E, Lahti, Jari, Liu, Yongmei, Marques-Vidal, Pedro, Mellström, Dan, Mooijaart, Simon P, Müller-Nurasyid, Martina, Penninx, Brenda, Revez, Joana A, Rossing, Peter, Räikkönen, Katri, Sattar, Naveed, Scharnagl, Hubert, Sennblad, Bengt, Silveira, Angela, Pourcain, Beate St, Timpson, Nicholas J, Trollor, Julian, van Dongen, Jenny, Van Heemst, Diana, Visvikis-Siest, Sophie, Vollenweider, Peter, Völker, Uwe, Waldenberger, Melanie, Willemsen, Gonneke, Zabaneh, Delilah, Morris, Richard W, Arnett, Donna K, Baune, Bernhard T, Boomsma, Dorret I, Chang, Yen-Pei C, Deary, Ian J, Deloukas, Panos, Eriksson, Johan G, Evans, David M, Ferreira, Manuel A, Gaunt, Tom, Gudnason, Vilmundur, Hamsten, Anders, Heinrich, Joachim, Hingorani, Aroon, Humphries, Steve E, Jukema, J Wouter, Koenig, Wolfgang, Kumari, Meena, Kutalik, Zoltan, Lawlor, Deborah A, Lehtimäki, Terho, März, Winfried, Mather, Karen A, Naitza, Silvia, Nauck, Matthias, Ohlsson, Claes, Price, Jackie F, Raitakari, Olli, Rice, Ken, Sachdev, Perminder S, Slagboom, Eline, Sørensen, Thorkild I A, Spector, Tim, Stacey, David, Stathopoulou, Maria G, Tanaka, Toshiko, Wannamethee, S Goya, Whincup, Peter, Rotter, Jerome I, Dehghan, Abbas, Boerwinkle, Eric, Psaty, Bruce M, Snieder, Harold, Alizadeh, Behrooz Z

Source: Human molecular genetics. 30(5):393-409

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121745118.0x000001&indx=1&recIds=ETOCvdc_100121745118.0x000001

The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community

Authors: Kiel, Douglas P, Kemp, John P, Rivadeneira, Fernando, Westendorf, Jennifer J, Karasik, David, Duncan, Emma L, Imai, Yuuki, Müller, Ralph, Flannick, Jason, Bonewald, Lynda, Burtt, Noël

Source: Journal of bone and mineral research. 35(9):1626-1633

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115029936.0x000001&indx=1&recIds=ETOCvdc_100115029936.0x000001

The Effect of Plasma Lipids and Lipid‐Lowering Interventions on Bone Mineral Density: A Mendelian Randomization Study

Authors: Zheng, Jie, Brion, Marie‐Jo, Kemp, John P, Warrington, Nicole M, Borges, Maria‐Carolina, Hemani, Gibran, Richardson, Tom G, Rasheed, Humaira, Qiao, Zhen, Haycock, Philip, Ala‐Korpela, Mika, Davey Smith, George, Tobias, Jon H, Evans, David M

Source: Journal of bone and mineral research. 35(7):1224-1235

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107550451.0x000001&indx=1&recIds=ETOCvdc_100107550451.0x000001

A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD‐Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis

Authors: Gregson, Celia L, Bergen, Dylan J. M., Leo, Paul, Sessions, Richard B, Wheeler, Lawrie, Hartley, April, Youlten, Scott, Croucher, Peter I, McInerney‐Leo, Aideen M, Fraser, William, Tang, Jonathan CY, Anderson, Lisa, Marshall, Mhairi, Sergot, Leon, Paternoster, Lavinia, Davey Smith, George, Brown, Matthew A, Hammond, Chrissy, Kemp, John P, Tobias, Jon H, Duncan, Emma L

Source: Journal of bone and mineral research. 35(1):92-105

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099734313.0x000001&indx=1&recIds=ETOCvdc_100099734313.0x000001

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Authors: Alizadeh, Behrooz Z., Boezen, H. Marike, Franke, Lude, van der Harst, Pim, Navis, Gerjan, Rots, Marianne, Snieder, Harold, Swertz, Morris, Wolffenbuttel, Bruce H.R., Wijmenga, Cisca, Benjamin, Emelia, Chasman, Daniel I., Dehghan, Abbas, Ahluwalia, Tarunveer Singh, Meigs, James, Tracy, Russell, Ligthart, Symen, Bis, Josh, Eiriksdottir, Gudny, Pankratz, Nathan, Gross, Myron, Rainer, Alex, Wilson, James G., Psaty, Bruce M., Dupuis, Josee, Prins, Bram, Vaso, Urmo, Stathopoulou, Maria, Lehtimaki, Terho, Koenig, Wolfgang, Jamshidi, Yalda, Siest, Sophie, Abbasi, Ali, Uitterlinden, Andre G., Abdollahi, Mohammadreza, Schnabel, Renate, Schick, Ursula M., Nolte, Ilja M., Kraja, Aldi, Hsu, Yi-Hsiang, Tylee, Daniel S., Zwicker, Alyson, Uher, Rudolf, Davey-Smith, George, Morrison, Alanna C., Hicks, Andrew, van Duijn, Cornelia M., Ward-Caviness, Cavin, Boerwinkle, Eric, Rotter, J., Rice, Ken, Lange, Leslie, Perola, Markus, de Geus, Eco, Morris, Andrew P., Makela, Kari Matti, Stacey, David, Eriksson, Johan, Frayling, Tim M., Slagboom, Eline P., Vaez, Ahmad, Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Prins, Bram P., Van der Most, Peter J., Tanaka, Toshiko, Naderi, Elnaz, Rose, Lynda M., Wu, Ying, Karlsson, Robert, Barbalic, Maja, Lin, Honghuang, Pool, René, Zhu, Gu, Macé, Aurélien, Sidore, Carlo, Trompet, Stella, Mangino, Massimo, Sabater-Lleal, Maria, Kemp, John P., Kacprowski, Tim, Verweij, Niek, Smith, Albert V., Huang, Tao, Marzi, Carola, Feitosa, Mary F., Lohman, Kurt K., Kleber, Marcus E., Milaneschi, Yuri, Mueller, Christian, Huq, Mahmudul, Vlachopoulou, Efthymia, Lyytikäinen, Leo-Pekka, Oldmeadow, Christopher, Deelen, Joris, Zhao, Jing Hua, Feenstra, Bjarke, Amini, Marzyeh, Lahti, Jari, Schraut, Katharina E., Fornage, Myriam, Suktitipat, Bhoom, Chen, Wei-Min, Li, Xiaohui, Nutile, Teresa, Malerba, Giovanni, Luan, Jian’an, Bak, Tom, Schork, Nicholas, Del Greco M., Fabiola, Thiering, Elisabeth, Mahajan, Anubha, Marioni, Riccardo E., Mihailov, Evelin, Eriksson, Joel, Ozel, Ayse Bilge, Zhang, Weihua, Nethander, Maria, Cheng, Yu-Ching, Aslibekyan, Stella, Ang, Wei, Gandin, Ilaria, Yengo, Loïc, Portas, Laura, Kooperberg, Charles, Hofer, Edith, Rajan, Kumar B., Schurmann, Claudia, den Hollander, Wouter, Ahluwalia, Tarunveer S., Zhao, Jing, Draisma, Harmen H.M., Ford, Ian, Timpson, Nicholas, Teumer, Alexander, Huang, Hongyan, Wahl, Simone, Liu, YongMei, Huang, Jie, Uh, Hae-Won, Geller, Frank, Joshi, Peter K., Yanek, Lisa R., Trabetti, Elisabetta, Lehne, Benjamin, Vozzi, Diego, Verbanck, Marie, Biino, Ginevra, Saba, Yasaman, Meulenbelt, Ingrid, O’Connell, Jeff R., Laakso, Markku, Giulianini, Franco, Magnusson, Patrik K.E., Ballantyne, Christie M., Hottenga, Jouke Jan, Montgomery, Grant W., Rivadineira, Fernando, Rueedi, Rico, Steri, Maristella, Herzig, Karl-Heinz, Stott, David J., Menni, Cristina, Frånberg, Mattias, St. Pourcain, Beate, Felix, Stephan B., Pers, Tune H., Bakker, Stephan J.L., Kraft, Peter, Peters, Annette, Vaidya, Dhananjay, Delgado, Graciela, Smit, Johannes H., Großmann, Vera, Sinisalo, Juha, Seppälä, Ilkka, Williams, Stephen R., Holliday, Elizabeth G., Moed, Matthijs, Langenberg, Claudia, Räikkönen, Katri, Ding, Jingzhong, Campbell, Harry, Sale, Michele M., Chen, Yii-Der I., James, Alan L., Ruggiero, Daniela, Soranzo, Nicole, Hartman, Catharina A., Smith, Erin N., Berenson, Gerald S., Fuchsberger, Christian, Hernandez, Dena, Tiesler, Carla M.T., Giedraitis, Vilmantas, Liewald, David, Fischer, Krista, Mellström, Dan, Larsson, Anders, Wang, Yunmei, Scott, William R., Lorentzon, Matthias, Beilby, John, Ryan, Kathleen A., Pennell, Craig E., Vuckovic, Dragana, Balkau, Beverly, Concas, Maria Pina, Schmidt, Reinhold, Mendes de Leon, Carlos F., Bottinger, Erwin P., Kloppenburg, Margreet, Paternoster, Lavinia, Boehnke, Michael, Musk, A.W., Willemsen, Gonneke, Evans, David M., Madden, Pamela A.F., Kähönen, Mika, Kutalik, Zoltán, Zoledziewska, Magdalena, Karhunen, Ville, Kritchevsky, Stephen B., Sattar, Naveed, Lachance, Genevieve, Clarke, Robert, Harris, Tamara B., Raitakari, Olli T., Attia, John R., van Heemst, Diana, Kajantie, Eero, Sorice, Rossella, Gambaro, Giovanni, Scott, Robert A., Hicks, Andrew A., Ferrucci, Luigi, Standl, Marie, Lindgren, Cecilia M., Starr, John M., Karlsson, Magnus, Lind, Lars, Li, Jun Z., Chambers, John C., Mori, Trevor A., de Geus, Eco J.C.N., Heath, Andrew C., Martin, Nicholas G., Auvinen, Juha, Buckley, Brendan M., de Craen, Anton J.M., Waldenberger, Melanie, Strauch, Konstantin, Meitinger, Thomas, Scott, Rodney J., McEvoy, Mark, Beekman, Marian, Bombieri, Cristina, Ridker, Paul M., Mohlke, Karen L., Pedersen, Nancy L., Boomsma, Dorret I., Whitfield, John B., Strachan, David P., Hofman, Albert, Vollenweider, Peter, Cucca, Francesco, Jarvelin, Marjo-Riitta, Jukema, J. Wouter, Spector, Tim D., Hamsten, Anders, Zeller, Tanja, Uitterlinden, André G., Nauck, Matthias, Gudnason, Vilmundur, Qi, Lu, Grallert, Harald, Borecki, Ingrid B., Rotter, Jerome I., März, Winfried, Wild, Philipp S., Lokki, Marja-Liisa, Boyle, Michael, Salomaa, Veikko, Melbye, Mads, Eriksson, Johan G., Wilson, James F., Penninx, Brenda W.J.H., Becker, Diane M., Worrall, Bradford B., Gibson, Greg, Krauss, Ronald M., Ciullo, Marina, Zaza, Gianluigi, Wareham, Nicholas J., Oldehinkel, Albertine J., Palmer, Lyle J., Murray, Sarah S., Pramstaller, Peter P., Bandinelli, Stefania, Heinrich, Joachim, Ingelsson, Erik, Deary, Ian J., Mägi, Reedik, Vandenput, Liesbeth, Desch, Karl C., Kooner, Jaspal S., Ohlsson, Claes, Hayward, Caroline, Lehtimäki, Terho, Shuldiner, Alan R., Arnett, Donna K., Beilin, Lawrence J., Robino, Antonietta, Froguel, Philippe, Pirastu, Mario, Jess, Tine, Loos, Ruth J.F., Evans, Denis A., Schmidt, Helena, Smith, George Davey, Slagboom, P. Eline, Tracy, Russell P., Visvikis-Siest, Sophie, Reiner, Alex P., Bis, Joshua C., Franco, Oscar H., Benjamin, Emelia J., Dupuis, Josée

Source: In The American Journal of Human Genetics 1 November 2018 103(5):691-706

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

Authors: Medina-Gomez, Carolina, Kemp, John P., Trajanoska, Katerina, Luan, Jian’an, Chesi, Alessandra, Ahluwalia, Tarunveer S., Mook-Kanamori, Dennis O., Ham, Annelies, Hartwig, Fernando P., Evans, Daniel S., Joro, Raimo, Nedeljkovic, Ivana, Zheng, Hou-Feng, Zhu, Kun, Atalay, Mustafa, Liu, Ching-Ti, Nethander, Maria, Broer, Linda, Porleifsson, Gudmar, Mullin, Benjamin H., Handelman, Samuel K., Nalls, Mike A., Jessen, Leon E., Heppe, Denise H.M., Richards, J. Brent, Wang, Carol, Chawes, Bo, Schraut, Katharina E., Amin, Najaf, Wareham, Nick, Karasik, David, Van der Velde, Nathalie, Ikram, M. Arfan, Zemel, Babette S., Zhou, Yanhua, Carlsson, Christian J., Liu, Yongmei, McGuigan, Fiona E., Boer, Cindy G., Bønnelykke, Klaus, Ralston, Stuart H., Robbins, John A., Walsh, John P., Zillikens, M. Carola, Langenberg, Claudia, Li-Gao, Ruifang, Williams, Frances M.K., Harris, Tamara B., Akesson, Kristina, Jackson, Rebecca D., Sigurdsson, Gunnar, den Heijer, Martin, van der Eerden, Bram C.J., van de Peppel, Jeroen, Spector, Timothy D., Pennell, Craig, Horta, Bernardo L., Felix, Janine F., Zhao, Jing Hua, Wilson, Scott G., de Mutsert, Renée, Bisgaard, Hans, Styrkársdóttir, Unnur, Jaddoe, Vincent W., Orwoll, Eric, Lakka, Timo A., Scott, Robert, Grant, Struan F.A., Lorentzon, Mattias, van Duijn, Cornelia M., Wilson, James F., Stefansson, Kari, Psaty, Bruce M., Kiel, Douglas P., Ohlsson, Claes, Ntzani, Evangelia, van Wijnen, Andre J., Forgetta, Vincenzo, Ghanbari, Mohsen, Logan, John G., Williams, Graham R., Bassett, J.H. Duncan, Croucher, Peter I., Evangelou, Evangelos, Uitterlinden, Andre G., Ackert-Bicknell, Cheryl L., Tobias, Jonathan H., Evans, David M., Rivadeneira, Fernando

Source: In The American Journal of Human Genetics 4 January 2018 102(1):88-102

A Metabolic Screen in Adolescents Reveals an Association Between Circulating Citrate and Cortical Bone Mineral Density

Authors: Kemp, John P, Sayers, Adrian, Fraser, William D, Davey Smith, George, Ala‐Korpela, Mika, Evans, David M, Tobias, Jonathan H

Source: Journal of bone and mineral research. 34(7):1306-1313

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088917869.0x000001&indx=1&recIds=ETOCvdc_100088917869.0x000001

An atlas of genetic influences on osteoporosis in humans and mice

Authors: Morris, John A., Kemp, John P., Youlten, Scott E., Laurent, Laetitia, Logan, John G., Chai, Ryan C., Vulpescu, Nicholas A., Forgetta, Vincenzo, Kleinman, Aaron, Mohanty, Sindhu T., Sergio, C. Marcelo, Quinn, Julian, Nguyen-Yamamoto, Loan, Luco, Aimee-Lee, Vijay, Jinchu, Simon, Marie-Michelle, Pramatarova, Albena, Medina-Gomez, Carolina, Trajanoska, Katerina, Ghirardello, Elena J., Butterfield, Natalie C., Curry, Katharine F., Leitch, Victoria D., Sparkes, Penny C., Adoum, Anne-Tounsia, Mannan, Naila S., Komla-Ebri, Davide S. K., Pollard, Andrea S., Dewhurst, Hannah F., Hassall, Thomas A. D., Beltejar, Michael-John G., Adams, Douglas J., Vaillancourt, Suzanne M., Kaptoge, Stephen, Baldock, Paul, Cooper, Cyrus, Reeve, Jonathan, Ntzani, Evangelia E., Evangelou, Evangelos, Ohlsson, Claes, Karasik, David, Rivadeneira, Fernando, Kiel, Douglas P., Tobias, Jonathan H., Gregson, Celia L., Harvey, Nicholas C., Grundberg, Elin, Goltzman, David, Adams, David J., Lelliott, Christopher J., Hinds, David A., Ackert-Bicknell, Cheryl L., Hsu, Yi-Hsiang, Maurano, Matthew T., Croucher, Peter I., Williams, Graham R., Bassett, J. H. Duncan, Evans, David M., Richards, J. Brent

Source: Nature genetics. 51(2):258-266

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193643935.0x000001&indx=1&recIds=ETOCvdc_100193643935.0x000001

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

Authors: Tachmazidou, Ioanna, Süveges, Dániel, Min, Josine L., Ritchie, Graham R.S., Steinberg, Julia, Walter, Klaudia, Iotchkova, Valentina, Schwartzentruber, Jeremy, Huang, Jie, Memari, Yasin, McCarthy, Shane, Crawford, Andrew A., Bombieri, Cristina, Cocca, Massimiliano, Farmaki, Aliki-Eleni, Gaunt, Tom R., Jousilahti, Pekka, Kooijman, Marjolein N., Lehne, Benjamin, Malerba, Giovanni, Männistö, Satu, Matchan, Angela, Medina-Gomez, Carolina, Metrustry, Sarah J., Nag, Abhishek, Ntalla, Ioanna, Paternoster, Lavinia, Rayner, Nigel W., Sala, Cinzia, Scott, William R., Shihab, Hashem A., Southam, Lorraine, St Pourcain, Beate, Traglia, Michela, Trajanoska, Katerina, Zaza, Gialuigi, Zhang, Weihua, Artigas, María S., Bansal, Narinder, Benn, Marianne, Chen, Zhongsheng, Danecek, Petr, Lin, Wei-Yu, Locke, Adam, Luan, Jian’an, Manning, Alisa K., Mulas, Antonella, Sidore, Carlo, Tybjaerg-Hansen, Anne, Varbo, Anette, Zoledziewska, Magdalena, Finan, Chris, Hatzikotoulas, Konstantinos, Hendricks, Audrey E., Kemp, John P., Moayyeri, Alireza, Panoutsopoulou, Kalliope, Szpak, Michal, Wilson, Scott G., Boehnke, Michael, Cucca, Francesco, Di Angelantonio, Emanuele, Langenberg, Claudia, Lindgren, Cecilia, McCarthy, Mark I., Morris, Andrew P., Nordestgaard, Børge G., Scott, Robert A., Tobin, Martin D., Wareham, Nicholas J., Burton, Paul, Chambers, John C., Smith, George Davey, Dedoussis, George, Felix, Janine F., Franco, Oscar H., Gambaro, Giovanni, Gasparini, Paolo, Hammond, Christopher J., Hofman, Albert, Jaddoe, Vincent W.V., Kleber, Marcus, Kooner, Jaspal S., Perola, Markus, Relton, Caroline, Ring, Susan M., Rivadeneira, Fernando, Salomaa, Veikko, Spector, Timothy D., Stegle, Oliver, Toniolo, Daniela, Uitterlinden, André G., Barroso, Inês, Greenwood, Celia M.T., Perry, John R.B., Walker, Brian R., Butterworth, Adam S., Xue, Yali, Durbin, Richard, Small, Kerrin S., Soranzo, Nicole, Timpson, Nicholas J., Zeggini, Eleftheria

Source: In The American Journal of Human Genetics 1 June 2017 100(6):865-884

Genome Analyses of >200, 000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Authors: Ligthart, Symen, Vaez, Ahmad, Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Prins, Bram P., Van der Most, Peter J., Tanaka, Toshiko, Naderi, Elnaz, Rose, Lynda M., Wu, Ying, Karlsson, Robert, Barbalic, Maja, Lin, Honghuang, Pool, René, Zhu, Gu, Macé, Aurélien, Sidore, Carlo, Trompet, Stella, Mangino, Massimo, Sabater-Lleal, Maria, Kemp, John P., Abbasi, Ali, Kacprowski, Tim, Verweij, Niek, Smith, Albert V., Huang, Tao, Marzi, Carola, Feitosa, Mary F., Lohman, Kurt K., Kleber, Marcus E., Milaneschi, Yuri, Mueller, Christian, Huq, Mahmudul, Vlachopoulou, Efthymia, Lyytikäinen, Leo-Pekka, Oldmeadow, Christopher, Deelen, Joris, Perola, Markus, Zhao, Jing Hua, Feenstra, Bjarke, Amini, Marzyeh, Lahti, Jari, Schraut, Katharina E., Fornage, Myriam, Suktitipat, Bhoom, Chen, Wei-Min, Li, Xiaohui, Nutile, Teresa, Malerba, Giovanni, Luan, Jian'an, Bak, Tom, Schork, Nicholas, Del Greco M., Fabiola, Thiering, Elisabeth, Mahajan, Anubha, Marioni, Riccardo E., Mihailov, Evelin, Eriksson, Joel, Ozel, Ayse Bilge, Zhang, Weihua, Nethander, Maria, Cheng, Yu-Ching, Aslibekyan, Stella, Ang, Wei, Gandin, Ilaria, Yengo, Loïc, Portas, Laura, Kooperberg, Charles, Hofer, Edith, Rajan, Kumar B., Schurmann, Claudia, den Hollander, Wouter, Ahluwalia, Tarunveer S., Zhao, Jing, Draisma, Harmen H.M., Ford, Ian, Timpson, Nicholas, Teumer, Alexander, Huang, Hongyan, Wahl, Simone, Liu, YongMei, Huang, Jie, Uh, Hae-Won, Geller, Frank, Joshi, Peter K., Yanek, Lisa R., Trabetti, Elisabetta, Lehne, Benjamin, Vozzi, Diego, Verbanck, Marie, Biino, Ginevra, Saba, Yasaman, Meulenbelt, Ingrid, O'Connell, Jeff R., Laakso, Markku, Giulianini, Franco, Magnusson, Patrik K.E., Ballantyne, Christie M., Hottenga, Jouke Jan, Montgomery, Grant W., Rivadineira, Fernando, Rueedi, Rico, Steri, Maristella, Herzig, Karl-Heinz, Stott, David J., Menni, Cristina, Frånberg, Mattias, St. Pourcain, Beate, Felix, Stephan B., Pers, Tune H., Bakker, Stephan J.L., Kraft, Peter, Peters, Annette, Vaidya, Dhananjay, Delgado, Graciela, Smit, Johannes H., Großmann, Vera, Sinisalo, Juha, Seppälä, Ilkka, Williams, Stephen R., Holliday, Elizabeth G., Moed, Matthijs, Langenberg, Claudia, Räikkönen, Katri, Ding, Jingzhong, Campbell, Harry, Sale, Michele M., Chen, Yii-Der I., James, Alan L., Ruggiero, Daniela, Soranzo, Nicole, Hartman, Catharina A., Smith, Erin N., Berenson, Gerald S., Fuchsberger, Christian, Hernandez, Dena, Tiesler, Carla M.T., Giedraitis, Vilmantas, Liewald, David, Fischer, Krista, Mellström, Dan, Larsson, Anders, Wang, Yunmei, Scott, William R., Lorentzon, Matthias, Beilby, John, Ryan, Kathleen A., Pennell, Craig E., Vuckovic, Dragana, Balkau, Beverly, Concas, Maria Pina, Schmidt, Reinhold, Mendes de Leon, Carlos F., Bottinger, Erwin P., Kloppenburg, Margreet, Paternoster, Lavinia, Boehnke, Michael, Musk, A.W., Willemsen, Gonneke, Evans, David M., Madden, Pamela A.F., Kähönen, Mika, Kutalik, Zoltán, Zoledziewska, Magdalena, Karhunen, Ville, Kritchevsky, Stephen B., Sattar, Naveed, Lachance, Genevieve, Clarke, Robert, Harris, Tamara B., Raitakari, Olli T., Attia, John R., van Heemst, Diana, Kajantie, Eero, Sorice, Rossella, Gambaro, Giovanni, Scott, Robert A., Hicks, Andrew A., Ferrucci, Luigi, Standl, Marie, Lindgren, Cecilia M., Starr, John M., Karlsson, Magnus, Lind, Lars, Li, Jun Z., Chambers, John C., Mori, Trevor A., de Geus, Eco J.C.N., Heath, Andrew C., Martin, Nicholas G., Auvinen, Juha, Buckley, Brendan M., de Craen, Anton J.M., Waldenberger, Melanie, Strauch, Konstantin, Meitinger, Thomas, Scott, Rodney J., McEvoy, Mark, Beekman, Marian, Bombieri, Cristina, Ridker, Paul M., Mohlke, Karen L., Pedersen, Nancy L., Morrison, Alanna C., Boomsma, Dorret I., Whitfield, John B., Strachan, David P., Hofman, Albert, Vollenweider, Peter, Cucca, Francesco, Jarvelin, Marjo-Riitta, Jukema, J. Wouter, Spector, Tim D., Hamsten, Anders, Zeller, Tanja, Uitterlinden, André G., Nauck, Matthias, Gudnason, Vilmundur, Qi, Lu, Grallert, Harald, Borecki, Ingrid B., Rotter, Jerome I., März, Winfried, Wild, Philipp S., Lokki, Marja-Liisa, Boyle, Michael, Salomaa, Veikko, Melbye, Mads, Eriksson, Johan G., Wilson, James F., Penninx, Brenda W.J.H., Becker, Diane M., Worrall, Bradford B., Gibson, Greg, Krauss, Ronald M., Ciullo, Marina, Zaza, Gianluigi, Wareham, Nicholas J., Oldehinkel, Albertine J., Palmer, Lyle J., Murray, Sarah S., Pramstaller, Peter P., Bandinelli, Stefania, Heinrich, Joachim, Ingelsson, Erik, Deary, Ian J., Mägi, Reedik, Vandenput, Liesbeth, van der Harst, Pim, Desch, Karl C., Kooner, Jaspal S., Ohlsson, Claes, Hayward, Caroline, Lehtimäki, Terho, Shuldiner, Alan R., Arnett, Donna K., Beilin, Lawrence J., Robino, Antonietta, Froguel, Philippe, Pirastu, Mario, Jess, Tine, Koenig, Wolfgang, Loos, Ruth J.F., Evans, Denis A., Schmidt, Helena, Smith, George Davey, Slagboom, P. Eline, Eiriksdottir, Gudny, Morris, Andrew P., Psaty, Bruce M., Tracy, Russell P., Nolte, Ilja M., Boerwinkle, Eric, Visvikis-Siest, Sophie, Reiner, Alex P., Gross, Myron, Bis, Joshua C., Franke, Lude, Franco, Oscar H., Benjamin, Emelia J., Chasman, Daniel I., Dupuis, Josée, Snieder, Harold, Dehghan, Abbas, Alizadeh, Behrooz Z.

Source: American journal of human genetics. 103(5):691-706

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131834027.0x000001&indx=1&recIds=ETOCvdc_100131834027.0x000001

Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes

Authors: Gregson, Celia L., Newell, Felicity, Leo, Paul J., Clark, Graeme R., Paternoster, Lavinia, Marshall, Mhairi, Forgetta, Vincenzo, Morris, John A., Ge, Bing, Bao, Xiao, Duncan Bassett, J.H., Williams, Graham R., Youlten, Scott E., Croucher, Peter I., Davey Smith, George, Evans, David M., Kemp, John P., Brown, Matthew A., Tobias, Jon H., Duncan, Emma L.

Source: Bone. 114:62-71

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097098044.0x000001&indx=1&recIds=ETOCvdc_100097098044.0x000001

A Genome-Wide Association Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Symptoms in Population-Based Pediatric Cohorts

Authors: Middeldorp, Christel M., Hammerschlag, Anke R., Ouwens, Klaasjan G., Groen-Blokhuis, Maria M., St. Pourcain, Beate, Greven, Corina U., Pappa, Irene, Tiesler, Carla M.T., Ang, Wei, Nolte, Ilja M., Vilor-Tejedor, Natalia, Bacelis, Jonas, Ebejer, Jane L., Zhao, Huiying, Davies, Gareth E., Ehli, Erik A., Evans, David M., Fedko, Iryna O., Guxens, Mònica, Hottenga, Jouke-Jan, Hudziak, James J., Jugessur, Astanand, Kemp, John P., Krapohl, Eva, Martin, Nicholas G., Murcia, Mario, Myhre, Ronny, Ormel, Johan, Ring, Susan M., Standl, Marie, Stergiakouli, Evie, Stoltenberg, Camilla, Thiering, Elisabeth, Timpson, Nicholas J., Trzaskowski, Maciej, van der Most, Peter J., Wang, Carol, Nyholt, Dale R., Medland, Sarah E., Neale, Benjamin, Jacobsson, Bo, Sunyer, Jordi, Hartman, Catharina A., Whitehouse, Andrew J.O., Pennell, Craig E., Heinrich, Joachim, Plomin, Robert, Davey Smith, George, Tiemeier, Henning, Posthuma, Danielle, Boomsma, Dorret I.

Source: In Journal of the American Academy of Child & Adolescent Psychiatry October 2016 55(10):896-905

Femoral neck width genetic risk score is a novel independent risk factor for hip fractures.

Authors: Tobias, Jonathan H, Nethander, Maria, Faber, Benjamin G, Heppenstall, Sophie V, Ebsim, Raja, Cootes, Tim, Lindner, Claudia, Saunders, Fiona R, Gregory, Jenny S, Aspden, Richard M, Harvey, Nicholas C, Kemp, John P, Frysz, Monika, Ohlsson, Claes

Source: Journal of Bone & Mineral Research; Mar2024, Vol. 39 Issue 3, p241-251, 11p

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

Authors: PRACTICAL consortium, Davies, Neil M., Gaunt, Tom R., Lewis, Sarah J., Holly, Jeff, Donovan, Jenny L., Hamdy, Freddie C., Kemp, John P., Eeles, Rosalind, Easton, Doug, Kote-Jarai, Zsofia, Olama, Ali Amin Al, Benlloch, Sara, Muir, Kenneth, Giles, Graham G., Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher A., Schleutker, Johanna, Nordestgaard, Børge G., Travis, Ruth C., Neal, David, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L., Blot, William J., Thibodeau, Stephen, Maier, Christiane, Kibel, Adam S., Cybulski, Cezary, Cannon-Albright, Lisa, Brenner, Hermann, Park, Jong, Kaneva, Radka, Batra, Jyotsna, Teixeira, Manuel R., Pandha, Hardev, Lathrop, Mark, Smith, George Davey, Martin, Richard M.

Source: Cancer Causes & Control, 2015 Nov 01. 26(11), 1603-1616.

Access URL: http://www.jstor.org/stable/24716203