Frequency of weight and body composition increases in advanced non‐small cell lung cancer patients during first line therapy.

Authors: Bonomi, Philip, Moudgalya, Hita, Gomez, Sandra L., Shah, Palmi, Basu, Sanjib, Batus, Marta, Martinka, Levi B., Abdelkader, Ahmed, Tzameli, Iphigenia, Cobain, Sonia, Collins, Susie, Keliher, Edmund J., Breen, Danna M., Calle, Roberto A., Fidler, Mary Jo, Borgia, Jeffrey A.

Source: Journal of Cachexia, Sarcopenia & Muscle; Dec2024, Vol. 15 Issue 6, p2311-2322, 12p

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo

Authors: Wang, Cuihua, Keliher, Edmund, Zeller, Matthias W. G., Wojtkiewicz, Gregory R., Aguirre, Aaron D., Buckbinder, Leonard, Kim, Hye-Yeong, Chen, Jianqing, Maresca, Kevin, Ahmed, Maaz S., Motlagh, Negin Jalali, Nahrendorf, Matthias, Chen, John W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jun 01. 116(24), 11966-11971.

Access URL: https://www.jstor.org/stable/26743507

Anti–CTLA-4 therapy requires an Fc domain for efficacy

Authors: Ingram, Jessica R., Blomberg, Olga S., Rashidian, Mohammad, Ali, Lestat, Garforth, Scott, Fedorov, Elena, Fedorov, Alexander A., Bonanno, Jeffrey B., Le Gall, Camille, Crowley, Stephanie, Espinosa, Camilo, Biary, Tamara, Keliher, Edmund J., Weissleder, Ralph, Almo, Steven C., Dougan, Stephanie K., Ploegh, Hidde L., Dougan, Michael

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Apr 01. 115(15), 3912-3917.

Access URL: https://www.jstor.org/stable/26508484

Noninvasive imaging of immune responses

Authors: Rashidian, Mohammad, Keliher, Edmund J., Bilate, Angelina M., Duarte, Joao N., Wojtkiewicz, Gregory R., Jacobsen, Johanne Tracey, Cragnolini, Juanjo, Swee, Lee Kim, Victora, Gabriel D., Weissleder, Ralph, Ploegh, Hidde L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 May 01. 112(19), 6146-6151.

Access URL: https://www.jstor.org/stable/26462755

PD-L1 is an activation-independent marker of brown adipocytes

Authors: Ingram, Jessica, Dougan, Michael, Rashidian, Mohammad, Knoll, Marko, Keliher, Edmund, Garrett, Sarah, Garforth, Scott, Blomberg, Olga, Espinosa, Camilo, Bhan, Atul, Almo, Steven, Weissleder, Ralph, Lodish, Harvey, Dougan, Stephanie, Ploegh, Hidde

Source: Nature communications. 8(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182760092.0x000001&indx=1&recIds=ETOCvdc_100182760092.0x000001

Compositions and methods for in vivo imaging

Targeting Cathepsin E in Pancreatic Cancer by a Small Molecule Allows In Vivo Detection

Authors: Keliher, Edmund J., Reiner, Thomas, Earley, Sarah, Klubnick, Jenna, Tassa, Carlos, Lee, Andrew J., Ramaswamy, Sridhar, Bardeesy, Nabeel, Hanahan, Douglas, DePinho, Ronald A., Castro, Cesar M., Weissleder, Ralph

Source: In Neoplasia July 2013 15(7):684

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis

Authors: Ye, Yu-Xiang, Calcagno, Claudia, Binderup, Tina, Courties, Gabriel, Keliher, Edmund J., Wojtkiewicz, Gregory R., Iwamoto, Yoshiko, Tang, Jun, Pérez-Medina, Carlos, Mani, Venkatesh, Ishino, Seigo, Johnbeck, Camilla Bardram, Knigge, Ulrich, Fayad, Zahi A., Libby, Peter, Weissleder, Ralph, Tawakol, Ahmed, Dubey, Shipra, Belanger, Anthony P., Di Carli, Marcelo F., Swirski, Filip K., Kjaer, Andreas, Mulder, Willem J.M., Nahrendorf, Matthias

Source: Circulation research. 117(10):835-845

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037135566.0x000001&indx=1&recIds=ETOCvdc_100037135566.0x000001

Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo

Authors: Nair, Anil V., Keliher, Edmund J., Core, Amanda B., Brown, Dennis, Weissleder, Ralph

Source: ACS nano. 9(4):3641-3653

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600982837&indx=1&recIds=ETOCRN600982837

Reactive polymer enables efficient in vivo bioorthogonal chemistry

Authors: Devaraj, Neal K., Thurber, Greg M., Keliher, Edmund J., Marinelli, Brett, Weissleder, Ralph

Source: Proceedings of the National Academy of Sciences of the United States of America, 2012 Mar . 109(13), 4762-4767.

Access URL: https://www.jstor.org/stable/41588370

Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents

Authors: Reiner, Thomas, Lacy, Jessica, Keliher, Edmund J., Yang, Katherine S., Ullal, Adeeti, Kohler, Rainer H., Vinegoni, Claudio, Weissleder, Ralph

Source: In Neoplasia March 2012 14(3):169

Hybrid PET-optical imaging using targeted probes

Authors: Nahrendorf, Matthias, Keliher, Edmund, Marinelli, Brett, Waterman, Peter, Feruglio, Paolo Fumene, Fexon, Lioubov, Pivovarov, Misha, Swirski, Filip K., Pittet, Mikael J., Vinegoni, Claudio, Weissleder, Ralph, Wilson, Brian

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Apr . 107(17), 7910-7915.

Access URL: https://www.jstor.org/stable/25665458

Imaging beta cell mass

18F-4V for PET–CT Imaging of VCAM-1 Expression in Atherosclerosis

Authors: Nahrendorf, Matthias ^{†, ‡}, Keliher, Edmund ^†, Panizzi, Peter ^†, Zhang, Hanwen ^†, Hembrador, Sheena ^†, Figueiredo, Jose-Luiz ^†, Aikawa, Elena ^†, Kelly, Kimberly ^†, Libby, Peter ^{‡, §}, Weissleder, Ralph ^{†, ‡}

Source: In JACC: Cardiovascular Imaging October 2009 2(10):1213-1222

Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction.

Authors: Zeller, Matthias W. G., Wang, Cuihua, Keliher, Edmund J., Wojtkiewicz, Gregory R., Aguirre, Aaron, Maresca, Kevin, Su, Chunyan, Buckbinder, Leonard, Wang, Jing, Nahrendorf, Matthias, Chen, John W.

Source: International Journal of Molecular Sciences; Mar2023, Vol. 24 Issue 6, p5704, 11p

Subject Terms: POSITRON emission tomography, INTRACELLULAR tracking, MYOCARDIAL infarction, MYELOPEROXIDASE, AUTORADIOGRAPHY

An Effect of Bulk on the Ratio of Fragmentation to Stereomutation in Three Cyclobutane Dimers of 3-Methylenecholest-4-ene.

Authors: Doering, William von E., Keliher, Edmund J.

Source: Journal of the American Chemical Society; November 14 2007, Vol. 129 Issue 45, p13834-13839, 6p

Effect of Deuterium on the Kinetics of 1,5-Hydrogen Shifts: 5-Dideuteriomethylene-2,4,6,7,9-pentamethyl-11,11a-dihydro-12H-naphthacene.

Authors: Doering, William von E., Keliher, Edmund J.

Source: Journal of the American Chemical Society; March 7 2007, Vol. 129 Issue 9, p2488-2495, 8p

Perturbations by Phenyl on the 1,5-Hydrogen Shift in 1,3(Z)-Pentadiene. Another Chameleonic Transition Region?

Authors: Doering, William von E., Keliher, Edmund J., Zhao, Xin

Source: Journal of the American Chemical Society; November 3 2004, Vol. 126 Issue 43, p14206-14216, 11p

Target occupancy study and whole-body dosimetry with a MAGL PET ligand [¹¹C]PF-06809247 in non-human primates.

Authors: Arakawa, Ryosuke, Takano, Akihiro, Nag, Sangram, Jia, Zhisheng, Amini, Nahid, Maresca, Kevin P., Zhang, Lei, Keliher, Edmund J., Butler, Christopher R., Piro, Justin R., Samad, Tarek A., Smith, Deborah, Nason, Deane, O'Neil, Steve, Trapa, Patrick, Fonseca, Kari R., Litchfield, John, McCarthy, Timothy, Carson, Richard E., Halldin, Christer

Source: EJNMMI Research; 3/4/2022, Vol. 12 Issue 1, p1-9, 9p

Subject Terms: POSITRON emission tomography, KRA, PRIMATES, ARACHIDONIC acid, MALE models, SMALL intestine

Preclinical Evaluation of ⁸⁹Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy.

Authors: Maresca, Kevin P., Chen, Jianqing, Mathur, Divya, Giddabasappa, Anand, Root, Adam, Narula, Jatin, King, Lindsay, Schaer, David, Golas, Jonathan, Kobylarz, Keith, Rosfjord, Edward, Keliher, Edmund, Chen, Laigao, Ram, Sripad, Pickering, Eve H., Hardwick, James S., Rejto, Paul A., Hussein, Amira, Ilovich, Ohad, Staton, Kevin

Source: Molecular Imaging & Biology; Dec2021, Vol. 23 Issue 6, p941-951, 11p

Subject Terms: POSITRON emission tomography, T cells, COMPUTED tomography, BISPECIFIC antibodies, CELLULAR therapy, COLORECTAL cancer