Shotgun Metagenomics of Gastric Biopsies Reveals Compositional and Functional Microbiome Shifts in High- and Low-Gastric-Cancer-Risk Populations from Colombia, South America

Authors: Anthony Mannion, Alexander Sheh, Zeli Shen, JoAnn Dzink-Fox, M. Blanca Piazuelo, Keith T Wilson, Richard Peek, James G. Fox

Source: Gut Microbes, Vol 15, Iss 1 (2023)

Subject Terms: Helicobacter pylori, gastric cancer, gastric microbiome, whole metagenomic shotgun sequencing, 16S rRNA sequencing, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

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The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria.

Authors: Kshipra Singh, Nicole T Al-Greene, Thomas G Verriere, Lori A Coburn, Mohammad Asim, Daniel P Barry, Margaret M Allaman, Dana M Hardbower, Alberto G Delgado, M Blanca Piazuelo, Bruce A Vallance, Alain P Gobert, Keith T Wilson

Source: PLoS Pathogens, Vol 12, Iss 10, p e1005984 (2016)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5081186?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/dde25832be474145b30f534c31096627

Serum Fatty Acids Are Correlated with Inflammatory Cytokines in Ulcerative Colitis.

Authors: Dawn M Wiese, Sara N Horst, Caroline T Brown, Margaret M Allaman, Mallary E Hodges, James C Slaughter, Jennifer P Druce, Dawn B Beaulieu, David A Schwartz, Keith T Wilson, Lori A Coburn

Source: PLoS ONE, Vol 11, Iss 5, p e0156387 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4882051?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3a55dbd4926142afa64672cf0a83947e

High-throughput multi-analyte Luminex profiling implicates eotaxin-1 in ulcerative colitis.

Authors: Lori A Coburn, Sara N Horst, Rupesh Chaturvedi, Caroline T Brown, Margaret M Allaman, Brooks P Scull, Kshipra Singh, M Blanca Piazuelo, Maithili V Chitnavis, Mallary E Hodges, Michael J Rosen, Christopher S Williams, James C Slaughter, Dawn B Beaulieu, David A Schwartz, Keith T Wilson

Source: PLoS ONE, Vol 8, Iss 12, p e82300 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3867379?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d4d7f74ea15f44989f08172ba757ae3f

Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.

Authors: Caitlyn W Barrett, Kshipra Singh, Amy K Motley, Mary K Lintel, Elena Matafonova, Amber M Bradley, Wei Ning, Shenika V Poindexter, Bobak Parang, Vishruth K Reddy, Rupesh Chaturvedi, Barbara M Fingleton, Mary K Washington, Keith T Wilson, Sean S Davies, Kristina E Hill, Raymond F Burk, Christopher S Williams

Source: PLoS ONE, Vol 8, Iss 7, p e67845 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3701622?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ef779befc8d54e5d9a33d60fef5898e8

Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.

Authors: Jennifer M Noto, Tinatin Khizanishvili, Rupesh Chaturvedi, M Blanca Piazuelo, Judith Romero-Gallo, Alberto G Delgado, Shradha S Khurana, Johanna C Sierra, Uma S Krishna, Giovanni Suarez, Anne E Powell, James R Goldenring, Robert J Coffey, Vincent W Yang, Pelayo Correa, Jason C Mills, Keith T Wilson, Richard M Peek

Source: PLoS ONE, Vol 8, Iss 1, p e54344 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3553174?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1cc0b00deeb940f8b0d725b0b82385e7

Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.

Authors: Caitlyn W Barrett, J Joshua Smith, Lauren C Lu, Nicholas Markham, Kristy R Stengel, Sarah P Short, Baolin Zhang, Aubrey A Hunt, Barbara M Fingleton, Robert H Carnahan, Michael E Engel, Xi Chen, R Daniel Beauchamp, Keith T Wilson, Scott W Hiebert, Albert B Reynolds, Christopher S Williams

Source: PLoS ONE, Vol 7, Iss 12, p e51205 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3521008?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c68dbf655f9e45e5beff743698a8bd3e

Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor.

Authors: Lihong Wang, Liping Liu, Yan Shi, Hanwei Cao, Rupesh Chaturvedi, M Wade Calcutt, Tianhui Hu, Xiubao Ren, Keith T Wilson, D Brent Polk, Fang Yan

Source: PLoS ONE, Vol 7, Iss 5, p e36418 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3344856?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a440c293e88a40539fa74725efb7eb4c

L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis.

Authors: Lori A Coburn, Xue Gong, Kshipra Singh, Mohammad Asim, Brooks P Scull, Margaret M Allaman, Christopher S Williams, Michael J Rosen, M Kay Washington, Daniel P Barry, M Blanca Piazuelo, Robert A Casero, Rupesh Chaturvedi, Zhongming Zhao, Keith T Wilson

Source: PLoS ONE, Vol 7, Iss 3, p e33546 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3299802?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/533feca6ab3b4bd2a33c8baf8209e8b6

Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction.

Authors: Daniel P Barry, Mohammad Asim, David A Leiman, Thibaut de Sablet, Kshipra Singh, Robert A Casero, Rupesh Chaturvedi, Keith T Wilson

Source: PLoS ONE, Vol 6, Iss 2, p e17510 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3046249?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/caf3d875014246a289923380d70287b6

Cationic amino acid transporter 2 enhances innate immunity during Helicobacter pylori infection.

Authors: Daniel P Barry, Mohammad Asim, Brooks P Scull, M Blanca Piazuelo, Thibaut de Sablet, Nuruddeen D Lewis, Lori A Coburn, Kshipra Singh, Lesley G Ellies, Alain P Gobert, Rupesh Chaturvedi, Keith T Wilson

Source: PLoS ONE, Vol 6, Iss 12, p e29046 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3237590?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/09ba87fccc7840d89038169ee39687b0

Helicobacter pylori infection: pathogenesis.

Authors: Purvi C. Panchal, Joshua S. Forman, Darren R. Blumberg, Keith T. Wilson

Source: Current Opinion in Gastroenterology; Jan2003, Vol. 19 Issue 1, p4-10, 7p

The reverse transsulfuration pathway affects the colonic microbiota and contributes to colitis in mice

Authors: Alain P. Gobert, Yvonne L. Latour, Kara M. McNamara, Caroline V. Hawkins, Kamery J. Williams, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Alberto G. Delgado, Ginger L. Milne, Shilin Zhao, M. Blanca Piazuelo, M. Kay Washington, Lori A. Coburn, Keith T. Wilson

Source: Amino Acids, Vol 56, Iss 1, Pp 1-12 (2024)

Subject Terms: Cystathionine g-lyase, Inflammatory bowel disease, Colitis, Colitis-associated carcinogenesis, Cysteine, Gut microbiota, Biochemistry, QD415-436, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1438-2199

Access URL: https://doaj.org/article/699bc7b9acaf4d59bea2765f7ec37397

Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn’s disease

Authors: Jia Li, Alan J. Simmons, Caroline V. Hawkins, Sophie Chiron, Marisol A. Ramirez-Solano, Naila Tasneem, Harsimran Kaur, Yanwen Xu, Frank Revetta, Paige N. Vega, Shunxing Bao, Can Cui, Regina N. Tyree, Larry W. Raber, Anna N. Conner, Jennifer M. Pilat, Justin Jacobse, Kara M. McNamara, Margaret M. Allaman, Gabriella A. Raffa, Alain P. Gobert, Mohammad Asim, Jeremy A. Goettel, Yash A. Choksi, Dawn B. Beaulieu, Robin L. Dalal, Sara N. Horst, Baldeep S. Pabla, Yuankai Huo, Bennett A. Landman, Joseph T. Roland, Elizabeth A. Scoville, David A. Schwartz, M. Kay Washington, Yu Shyr, Keith T. Wilson, Lori A. Coburn, Ken S. Lau, Qi Liu

Source: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0ba81d63e38741479e8c66302f19cf18

Hypusination in intestinal epithelial cells protects mice from infectious colitis

Authors: Alain P. Gobert, Caroline V. Hawkins, Kamery J. Williams, Lydia A. Snyder, Daniel P. Barry, Mohammad Asim, Margaret M. Allaman, Kara M. McNamara, Alberto G. Delgado, Yu Wang, Shilin Zhao, Kristie L. Rose, M. Blanca Piazuelo, Keith T. Wilson

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Polyamines, hypusine, translation, attaching and effacing pathogen, Enteropathogenic Escherichia coli, Citrobacter rodentium, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/2fb1850dd0fb406b991131a6758490a3

Analysis of the effect of hypusination in myeloid cells on colitis and colitis-associated cancer

Authors: Alain P. Gobert, Jordan Finley, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Caroline V. Hawkins, Kamery J. Williams, Alberto G. Delagado, Raghavendra G. Mirmira, Shilin Zhao, M. Blanca Piazuelo, M. Kay Washington, Lori A. Coburn, Keith T. Wilson

Source: Heliyon, Vol 10, Iss 13, Pp e33838- (2024)

Subject Terms: Inflammatory bowel diseases, Inflammation, Hypusine, Colon, Colorectal cancer, Gut microbiota, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024098694; https://doaj.org/toc/2405-8440

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Myeloid deletion of talin-1 reduces mucosal macrophages and protects mice from colonic inflammation

Authors: Yvonne L. Latour, Kara M. McNamara, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Mohammad Asim, Kamery J. Williams, Caroline V. Hawkins, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, M. Kay Washington, Alain P. Gobert, Keith T. Wilson

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fb0bf8276c3646598c802c501115e29e

Gastric coinfection with thiopeptide-positive Cutibacterium acnes decreases FOXM1 and pro-inflammatory biomarker expression in a murine model of Helicobacter pylori-induced gastric cancer

Authors: Courtney Lunger, Zeli Shen, Hilda Holcombe, Anthony J. Mannion, JoAnn Dzink-Fox, Susanna Kurnick, Yan Feng, Sureshkumar Muthupalani, Sebastian E. Carrasco, Keith T. Wilson, Richard M. Peek, M. Blanca Piazuelo, Douglas R. Morgan, Amanda L. Armijo, Melissa Mammoliti, Timothy C. Wang, James G. Fox

Source: Microbiology Spectrum, Vol 12, Iss 1 (2024)

Subject Terms: Helicobacter pylori, non-H. pylori gastric bacteria, Cutibacterium acnes, thiopeptide, gnotobiotic mouse model, mouse model of H. pylori-induced gastric cancer, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/0cc4e0cdd03c4002a30d01f014dbcd22

Epithelial talin-1 protects mice from Citrobacter rodentium-induced colitis by restricting bacterial crypt intrusion and enhancing T cell immunity

Authors: Yvonne L. Latour, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Kamery J. Williams, Kara M. McNamara, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, Shilin Zhao, Alain P. Gobert, Keith T. Wilson

Source: Gut Microbes, Vol 15, Iss 1 (2023)

Subject Terms: Talin, C. rodentium, colonic epithelial cells, neutrophils, T cells, colon organoids, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/f9ea48e1d73a40c2ba5b50cc0608468a

Induction and Regulation of the Innate Immune Response in Helicobacter pylori InfectionSummary

Authors: Alain P. Gobert, Keith T. Wilson

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1347-1363 (2022)

Subject Terms: Gastric Cancer, Gastritis, Microbiota, Polymorphism, Virulence Factors, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X22000224; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/8061b2be947544e0b5009b5b2bbcc402