Phosphodiesterase 5 expression in photoreceptors rescues retinal degeneration induced by deregulation of membrane guanylyl cyclase

Authors: Dizhoor, Alexander M. ^{1, 2, 3, ∗, #}, Sato, Shinya ^{4, #}, Luo, Zhuokai ^{1, 2, #}, Tan, Lyuqi ^{1, 2}, Levin, Fay E. ^{1, §}, Olshevskaya, Elena V. ¹, Peshenko, Igor V. ¹, Kefalov, Vladimir J. ^{4, 5}

Source: In Journal of Biological Chemistry March 2025 301(3)

Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors

Authors: Bassetto, Marco, Kolesnikov, Alexander V., Lewandowski, Dominik, Kiser, Jianying Z., Halabi, Maximilian, Einstein, David E., Choi, Elliot H., Palczewski, Krzysztof, Kefalov, Vladimir J., Kiser, Philip D.

Source: In Cell Reports 28 May 2024 43(5)

Light regulation of rhodopsin distribution during outer segment renewal in murine rod photoreceptors

Authors: Rose, Kasey, Chen, Natalie, Andreev, Andrey, Chen, Jiayan, Kefalov, Vladimir J., Chen, Jeannie

Source: In Current Biology 8 April 2024 34(7):1492-1505

SI Correction

Authors: Volkov, Leo I., Kim-Han, Jeong Sook, Saunders, Lauren M., Poria, Deepak, Hughes, Andrew E. O., Kefalov, Vladimir J., Parichy, David M., Corbo, Joseph C.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Nov . 118(48), 1-1.

Access URL: https://www.jstor.org/stable/27094103

Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision

Authors: Volkov, Leo I., Kim-Han, Jeong Sook, Saunders, Lauren M., Poria, Deepak, Hughes, Andrew E. O., Kefalov, Vladimir J., Parichy, David M., Corbo, Joseph C.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun . 117(26), 15262-15269.

Access URL: https://www.jstor.org/stable/26935076

Differential impact of Kv8.2 loss on rod and cone signaling and degeneration

Authors: Inamdar, Shivangi M, Lankford, Colten K, Poria, Deepak, Laird, Joseph G, Solessio, Eduardo, Kefalov, Vladimir J, Baker, Sheila A

Source: Human molecular genetics. 31(7):1035-1050

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100145914532.0x000001&indx=1&recIds=ETOCvdc_100145914532.0x000001

Samd7 represses short-wavelength cone genes to preserve long-wavelength cone and rod photoreceptor identity.

Authors: Volkov, Leo I., Ogawa, Yohey, Somjee, Ramiz, Vedder, Hannah E., Powell, Hannah E., Poria, Deepak, Meiselman, Sam, Kefalov, Vladimir J., Corbo, Joseph C.

Source: Proceedings of the National Academy of Sciences of the United States of America; 11/19/2024, Vol. 121 Issue 47, p1-10, 34p

Subject Terms: GENETIC regulation, GENE expression, TRANSCRIPTION factors, RETINA, PHOTORECEPTORS

Light deprivation reduces the severity of experimental diabetic retinopathy

Authors: Thebeau, Christina, Zhang, Sheng, Kolesnikov, Alexander V., Kefalov, Vladimir J., Semenkovich, Clay F., Rajagopal, Rithwick

Source: In Neurobiology of Disease April 2020 137

Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

Authors: Tworak, Aleksander, Kolesnikov, Alexander V., Hong, John D., Choi, Elliot H., Luu, Jennings C., Palczewska, Grazyna, Dong, Zhiqian, Lewandowski, Dominik, Brooks, Matthew J., Campello, Laura, Swaroop, Anand, Kiser, Philip D., Kefalov, Vladimir J., Palczewski, Krzysztof

Source: Cell reports. 42(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196442825.0x000001&indx=1&recIds=ETOCvdc_100196442825.0x000001

20 - Light Adaptation in Photoreceptors

Authors: Lamb, Trevor D., Kefalov, Vladimir J.

Source: In Adler's Physiology of the Eye Edition: Twelfth Edition. 2025:451-463

Sensitivity of Mammalian Cone Photoreceptors to Infrared Light

Authors: Vinberg, Frans, Palczewska, Grazyna, Zhang, Jianye, Komar, Katarzyna, Wojtkowski, Maciej, Kefalov, Vladimir J., Palczewski, Krzysztof

Source: In Neuroscience 15 September 2019 416:100-108

Photoreceptors in a mouse model of Leigh syndrome are capable of normal light-evoked signaling

Alternate Title: Retinal signaling in NDUFS4-deficient mice (English)

Authors: Gospe, Sidney M., III, Travis, Amanda M., Kolesnikov, Alexander V., Klingeborn, Mikael, Wang, Luyu, Kefalov, Vladimir J., Arshavsky, Vadim Y.

Source: In Journal of Biological Chemistry 16 August 2019 294(33):12432-12443

Mislocalization of cone nuclei impairs cone function in mice

Authors: Xue, Yunlu, Razafsky, David, Hodzic, Didier, Kefalov, Vladimir J.

Source: FASEB journal. 34(8):10242-10249

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122653824.0x000001&indx=1&recIds=ETOCvdc_100122653824.0x000001

Phosphorylation at Serine 21 in G protein‐coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors

Authors: Kolesnikov, Alexander V., Chrispell, Jared D., Osawa, Shoji, Kefalov, Vladimir J., Weiss, Ellen R.

Source: FASEB journal. 34(2):2677-2690

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108250982.0x000001&indx=1&recIds=ETOCvdc_100108250982.0x000001

Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors

Authors: Vinberg, Frans, Chen, Jeannie, Kefalov, Vladimir J.

Source: In Progress in Retinal and Eye Research November 2018 67:87-101

Guanylate cyclase–activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors

Authors: Vinberg, Frans, Peshenko, Igor V., Chen, Jeannie, Dizhoor, Alexander M., Kefalov, Vladimir J.

Source: In Journal of Biological Chemistry 11 May 2018 293(19):7457-7465

LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors

Authors: Sarria, Ignacio, Cao, Yan, Wang, Yuchen, Ingram, Norianne T., Orlandi, Cesare, Kamasawa, Naomi, Kolesnikov, Alexander V., Pahlberg, Johan, Kefalov, Vladimir J., Sampath, Alapakkam P., Martemyanov, Kirill A.

Source: In Cell Reports 27 March 2018 22(13):3562-3573

Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State

Authors: Sato, Shinya, Jastrzebska, Beata, Engel, Andreas, Palczewski, Krzysztof, Kefalov, Vladimir J.

Source: Journal of neuroscience. 39(2):212-223

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618623190&indx=1&recIds=ETOCRN618623190

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

Authors: Kiser, Philip D., Kolesnikov, Alexander V., Kiser, Jianying Z., Dong, Zhiqian, Chaurasia, Bhagirath, Wang, Liping, Summers, Scott A., Hoang, Thanh, Blackshaw, Seth, Peachey, Neal S., Kefalov, Vladimir J., Palczewski, And Krzysztof

Source: FASEB journal. 33(4):5782-5792

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103323629.0x000001&indx=1&recIds=ETOCvdc_100103323629.0x000001

Acyl‐CoA:wax alcohol acyltransferase 2 modulates the cone visual cycle in mouse retina

Authors: Widjaja‐Adhi, Made Airanthi K., Kolesnikov, Alexander V., Vasudevan, Sreelakshmi, Park, Paul S.‐H., Kefalov, Vladimir J., Golczak, Marcin

Source: FASEB journal. 36(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194591791.0x000001&indx=1&recIds=ETOCvdc_100194591791.0x000001