3D genome remodeling and homologous pairing during meiotic prophase of mouse oogenesis and spermatogenesis

Authors: He, Jing, Yan, An, Chen, Bo, Huang, Jiahui, Kee, Kehkooi

Source: In Developmental Cell 18 December 2023 58(24):3009-3027

Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells

Authors: Pistollato, Francesca, Bal-Price, Anna, Coecke, Sandra, Parvatam, Surat, Pamies, David, Czysz, Katherine, Hao, Jie, Kee, Kehkooi, Teo, Adrian Kee Keong, Niu, Shuaishuai, Wilmes, Anja, Smirnova, Lena, Freund, Christian, Mummery, Christine, Stacey, Glyn

Source: REPRODUCTIVE TOXICOLOGY -NEW YORK. 112:36-50

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175926773.0x000001&indx=1&recIds=ETOCvdc_100175926773.0x000001

SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility

Authors: Kuang, Wenhua, Zhang, Jie, Lan, Zhou, Deepak, R.N.V. Krishna, Liu, Chao, Ma, Zhilong, Cheng, Lili, Zhao, Xinbin, Meng, Xianbin, Wang, Weihua, Wang, Xueying, Xu, Lina, Jiao, Yupei, Luo, Qi, Meng, Ziyi, Kee, Kehkooi, Liu, Xiaohui, Deng, Haiteng, Li, Wei, Fan, Hao, Chen, Ligong

Source: In Cell Reports 20 April 2021 35(3)

Multi‐Omics Analysis Reveals Translational Landscapes and Regulations in Mouse and Human Oocyte Aging

Authors: Huang, Jiana, Chen, Peigen, Jia, Lei, Li, Tingting, Yang, Xing, Liang, Qiqi, Zeng, Yanyan, Liu, Jiawen, Wu, Taibao, Hu, Wenqi, Kee, Kehkooi, Zeng, Haitao, Liang, Xiaoyan, Zhou, Chuanchuan

Source: Advanced science. 10(26)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192926644.0x000001&indx=1&recIds=ETOCvdc_100192926644.0x000001

FAK-targeting PROTAC as a chemical tool for the investigation of non-enzymatic FAK function in mice

Authors: Gao, Hongying, Zheng, Chunwei, Du, Jian, Wu, Yue, Sun, Yonghui, Han, Chunsheng, Kee, Kehkooi, Rao, Yu

Source: Protein & cell. 11(7):534-539

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171461237.0x000001&indx=1&recIds=ETOCvdc_100171461237.0x000001

Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution

Authors: Zhu, Chenxu, Gao, Yun, Guo, Hongshan, Xia, Bo, Song, Jinghui, Wu, Xinglong, Zeng, Hu, Kee, Kehkooi, Tang, Fuchou, Yi, Chengqi

Source: In Cell Stem Cell 4 May 2017 20(5):720-731

FOXL2 and NR5A1 induce human fibroblasts into steroidogenic ovarian granulosa‐like cells.

Authors: Wen, Fan, Ding, Yuxi, Wang, Mingming, Du, Jing, Zhang, Shen, Kee, Kehkooi

Source: Cell Proliferation; May2024, Vol. 57 Issue 5, p1-16, 16p

Subject Terms: GRANULOSA cells, PROGESTERONE receptors, FIBROBLASTS, POLYCYSTIC ovary syndrome, DEVELOPMENTAL programs, CD55 antigen

A homozygous NOBOX truncating variant causes defective transcriptional activation and leads to primary ovarian insufficiency

Authors: Li, Lin, Wang, Binbin, Zhang, Wei, Chen, Beili, Luo, Minna, Wang, Jing, Wang, Xi, Cao, Yunxia, Kee, Kehkooi

Source: Human reproduction. 32(1):248-255

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100075002896.0x000001&indx=1&recIds=ETOCvdc_100075002896.0x000001

Generating a Genome Editing Nuclease for Targeted Mutagenesis in Human Cells

Authors: He, Zhenyu, Kee, Kehkooi

Source: Methods in molecular biology. 1498:153-162

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608394885&indx=1&recIds=ETOCRN608394885

Insights into female germ cell biology: from in vivo development to in vitro derivations

Authors: Jung, Dajung, Kee, Kehkooi

Source: Asian journal of andrology. 17(3):415-420

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088643379.0x000001&indx=1&recIds=ETOCvdc_100088643379.0x000001

LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress

Authors: Nguyen, Ha Nam, Byers, Blake, Cord, Branden, Shcheglovitov, Aleksandr, Byrne, James, Gujar, Prachi, Kee, Kehkooi, Schüle, Birgitt, Dolmetsch, Ricardo E., Langston, William, Palmer, Theo D., Pera, Renee Reijo

Source: In Cell Stem Cell 2011 8(3):267-280

IGSF11 is required for pericentric heterochromatin dissociation during meiotic diplotene.

Authors: Chen, Bo¹, Zhu, Gengzhen^2,3, Yan, An¹, He, Jing¹, Liu, Yang⁴, Li, Lin⁵, Yang, Xuerui⁴, Dong, Chen^2,3, Kee, Kehkooi¹, kkee@tsinghua.edu.cn

Source: PLoS Genetics; 9/7/2021, Vol. 17 Issue 9, p1-29, 29p

Chromatin accessibility landscape of mouse early embryos revealed by single-cell NanoATAC-seq2.

Authors: Li, Mengyao, Jiang, Zhenhuan, Xu, Xueqiang, Wu, Xinglong, Liu, Yun, Chen, Kexuan, Liao, Yuhan, Li, Wen, wenlu@pku.edu.cn, Wang, Xiao, Guo, Yuqing, Zhang, Bo, Wen, Lu, Kee, Kehkooi, kkee@mail.tsinghua.edu.cn, Tang, Fuchou, tangfuchou@pku.edu.cn

Source: Science; 3/28/2025, Vol. 387 Issue 6741, p1373-1373, 1p, 1 Color Photograph

5-Formylcytosine landscapes of human preimplantation embryos at single-cell resolution.

Authors: Gao, Yun^1,2, Li, Lin³, Yuan, Peng^1,4, Zhai, Fan^1,4, Ren, Yixin^1,4, Yan, Liying^1,4,5, Li, Rong^1,4, Lian, Ying^1,4, Zhu, Xiaohui^1,4, Wu, Xinglong^1,2,6,7, Kee, Kehkooi⁸, Wen, Lu^1,2, Qiao, Jie^1,4,5,6, jie.qiao@263.net, Tang, Fuchou^1,2,6, jie.qiao@263.net

Source: PLoS Biology; 7/30/2020, Vol. 18 Issue 7, p1-23, 23p, 6 Graphs

Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer

Authors: McElroy, Sohyun Lee, Kee, Kehkooi, Tran, Nam, Menses, Juanito, Giudice, Linda C, Reijo Pera, Renee A

Source: In Reproductive BioMedicine Online 2008 16(5):684-693

A Nodal enhanced micropeptide NEMEP regulates glucose uptake during mesendoderm differentiation of embryonic stem cells.

Authors: Fu, Haipeng, Wang, Tingyu, Kong, Xiaohui, Yan, Kun, Yang, Yang, Cao, Jingyi, Yuan, Yafei, Wang, Nan, Kee, Kehkooi, Lu, Zhi John, Xi, Qiaoran

Source: Nature Communications; 7/9/2022, Vol. 13 Issue 1, p1-17, 17p

Subject Terms: EMBRYONIC stem cells, CELL determination, GLUCOSE, GLUCOSE transporters, PHYSIOLOGY, INSULIN receptors

Cyclin-Dependent Kinase Directly Regulates Initiation of Meiotic Recombination

Authors: Henderson, Kiersten A., Kee, Kehkooi, Maleki, Shohreh, Santini, Paul A., Keeney, Scott

Source: In Cell 2006 125(7):1321-1332

Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation.

Authors: Kee, Kehkooi, Angeles, Vanessa T., Flores, Martha

Source: Nature; November 12 2009, Vol. 462, p222-225, 4p

Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae.

Authors: Kee, Kehkooi, Keeney, Scott

Source: Genetics; January 2002, Vol. 160 Issue 1, p111-122, 12p

Antiviral Protein Ski8 Is a Direct Partner of Spo11 in Meiotic DNA Break Formation, Independent of Its Cytoplasmic Role in RNA Metabolism

Authors: Arora, Charanjit, Kee, Kehkooi, Maleki, Shohreh, Keeney, Scott ^*

Source: In Molecular Cell 2004 13(4):549-559