Misclassified Alcohol-related Liver Disease is Common in Presumed Metabolic Dysfunction-associated Steatotic Liver Disease and Highly Increases Risk for Future Cirrhosis

Authors: Nasr, Patrik, Wester, Axel, Ekstedt, Mattias, Strandberg, Rickard, Kechagias, Stergios, Shang, Ying, Widman, Linnea, Hagström, Hannes

Source: In Clinical Gastroenterology and Hepatology May 2024 22(5):1048-1057

The Swedish initiative for the study of Primary sclerosing cholangitis (SUPRIM)

Authors: Cornillet, Martin ^{a, h, ∗}, Villard, Christina ^{a, b, h}, Rorsman, Fredrik ^c, Molinaro, Antonio ^d, Nilsson, Emma ^e, Kechagias, Stergios ^f, von Seth, Erik ^{a, g}, Bergquist, Annika ^{a, g, ∗∗}

Source: In eClinicalMedicine April 2024 70

Long-term major adverse liver outcomes in 1,260 patients with non-cirrhotic NAFLD

Authors: Akbari, Camilla, Dodd, Maja, Stål, Per, Nasr, Patrik, Ekstedt, Mattias, Kechagias, Stergios, Vessby, Johan, Rorsman, Fredrik, Zhang, Xiao, Wang, Tongtong, Jemielita, Thomas, Fernandes, Gail, Engel, Samuel S., Hagström, Hannes, Shang, Ying

Source: In JHEP Reports February 2024 6(2)

Impact on follow‐up strategies in patients with primary sclerosing cholangitis

Authors: Bergquist, Annika, Weismüller, Tobias J., Levy, Cynthia, Rupp, Christian, Joshi, Deepak, Nayagam, Jeremy Shanika, Montano‐Loza, Aldo J., Lytvyak, Ellina, Wunsch, Ewa, Milkiewicz, Piotr, Zenouzi, Roman, Schramm, Christoph, Cazzagon, Nora, Floreani, Annarosa, Liby, Ingalill Friis, Wiestler, Miriam, Wedemeyer, Heiner, Zhou, Taotao, Strassburg, Christian P., Rigopoulou, Eirini, Dalekos, George, Narasimman, Manasa, Verhelst, Xavier, Degroote, Helena, Vesterhus, Mette, Kremer, Andreas E., Bündgens, Bennet, Rorsman, Fredrik, Nilsson, Emma, Jørgensen, Kristin Kaasen, von Seth, Erik, Cornillet Jeannin, Martin, Nyhlin, Nils, Martin, Harry, Kechagias, Stergios, Wiencke, Kristine, Werner, Mårten, Beretta‐Piccoli, Benedetta Terziroli, Marzioni, Marco, Isoniemi, Helena, Arola, Johanna, Wefer, Agnes, Söderling, Jonas, Färkkilä, Martti, Lenzen, Henrike

Source: Liver international. 43(1):127-138

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194173300.0x000001&indx=1&recIds=ETOCvdc_100194173300.0x000001

Prospective surveillance for cholangiocarcinoma in unselected individuals with primary sclerosing cholangitis

Authors: Villard, Christina, Friis-Liby, Ingalill, Rorsman, Fredrik, Said, Karouk, Warnqvist, Anna, Cornillet, Martin, Kechagias, Stergios, Nyhlin, Nils, Werner, Mårten, Janczewska, Izabella, Hagström, Therese, Nilsson, Emma, Bergquist, Annika

Source: Journal of hepatology. 78(3):604-613

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183742093.0x000001&indx=1&recIds=ETOCvdc_100183742093.0x000001

Oral omeprazole and diclofenac intake is associated with increased faecal calprotectin levels: a randomised open-label clinical trial

Authors: Rendek, Zlatica, Falk, Magnus, Grodzinsky, Ewa, Kechagias, Stergios, Hjortswang, Henrik

Source: European journal of gastroenterology & hepatology. 35(1):52-58

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179174187.0x000001&indx=1&recIds=ETOCvdc_100179174187.0x000001

Disease Progression Modeling for Economic Evaluation in Nonalcoholic Fatty Liver Disease—A Systematic Review

Authors: Gruneau, Lina, Ekstedt, Mattias, Kechagias, Stergios, Henriksson, Martin

Source: Clinical gastroenterology and hepatology. 21(2):283-298

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179203429.0x000001&indx=1&recIds=ETOCvdc_100179203429.0x000001

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

Authors: Anstee, Quentin M, Daly, Ann K, Govaere, Olivier, Cockell, Simon, Tiniakos, Dina, Bedossa, Pierre, Burt, Alastair, Oakley, Fiona, Cordell, Heather J, Day, Christopher P, Wonders, Kristy, Missier, Paolo, McTeer, Matthew, Vale, Luke, Oluboyede, Yemi, Breckons, Matt, Bossuyt, Patrick M, Zafarmand, Hadi, Vali, Yasaman, Lee, Jenny, Nieuwdorp, Max, Holleboom, Adriaan G, Verheij, Joanne, Ratziu, Vlad, Clément, Karine, Patino-Navarrete, Rafael, Pais, Raluca, Paradis, Valerie, Schuppan, Detlef, Schattenberg, Jörn M, Surabattula, Rambabu, Myneni, Sudha, Straub, Beate K, Vidal-Puig, Toni, Vacca, Michele, Rodrigues-Cuenca, Sergio, Allison, Mike, Kamzolas, Ioannis, Petsalaki, Evangelia, Campbell, Mark, Lelliott, Chris J, Davies, Susan, Orešič, Matej, Hyötyläinen, Tuulia, McGlinchey, Aiden, Mato, Jose M, Millet, Óscar, Dufour, Jean-François, Berzigotti, Annalisa, Masoodi, Mojgan, Pavlides, Michael, Harrison, Stephen, Neubauer, Stefan, Cobbold, Jeremy, Mozes, Ferenc, Akhtar, Salma, Olodo-Atitebi, Seliat, Banerjee, Rajarshi, Kelly, Matt, Shumbayawonda, Elizabeth, Dennis, Andrea, Andersson, Anneli, Wigley, Ioan, Romero-Gómez, Manuel, Gómez-González, Emilio, Ampuero, Javier, Castell, Javier, Gallego-Durán, Rocío, Fernández, Isabel, Montero-Vallejo, Rocío, Karsdal, Morten, Rasmussen, Daniel Guldager Kring, Leeming, Diana Julie, Sinisi, Antonia, Musa, Kishwar, Sandt, Estelle, Tonini, Manuela, Bugianesi, Elisabetta, Rosso, Chiara, Armandi, Angelo, Marra, Fabio, Gastaldelli, Amalia, Svegliati, Gianluca, Boursier, Jérôme, Francque, Sven, Vonghia, Luisa, Driessen, Ann, Ekstedt, Mattias, Kechagias, Stergios, Yki-Järvinen, Hannele, Porthan, Kimmo, Arola, Johanna, van Mil, Saskia, Papatheodoridis, George, Cortez-Pinto, Helena, Rodrigues, Cecilia M P, Valenti, Luca, Pelusi, Serena, Petta, Salvatore, Pennisi, Grazia, Miele, Luca, Geier, Andreas, Trautwein, Christian, Reißing, Johanna, Aithal, Guruprasad P, Francis, Susan, Palaniyappan, Naaventhan, Bradley, Christopher, Hockings, Paul, Schneider, Moritz, Newsome, Philip, Hübscher, Stefan, Wenn, David, Rosenquist, Christian, Trylesinski, Aldo, Mayo, Rebeca, Alonso, Cristina, Duffin, Kevin, Perfield, James W, Chen, Yu, Yunis, Carla, Tuthill, Theresa, Harrington, Magdalena Alicia, Miller, Melissa, Chen, Yan, McLeod, Euan James, Ross, Trenton, Bernardo, Barbara, Schölch, Corinna, Ertle, Judith, Younes, Ramy, Oldenburger, Anouk, Coxson, Harvey, Ostroff, Rachel, Alexander, Leigh, Biegel, Hannah, Kjær, Mette Skalshøi, Harder, Lea Mørch, Davidsen, Peter, Ellegaard, Jens, Balp, Maria-Magdalena, Brass, Clifford, Jennings, Lori, Martic, Miljen, Löffler, Jürgen, Applegate, Douglas, Shankar, Sudha, Torstenson, Richard, Lindén, Daniel, Fournier-Poizat, Céline, Llorca, Anne, Kalutkiewicz, Michael, Pepin, Kay, Ehman, Richard, Horan, Gerald, Ho, Gideon, Tai, Dean, Chng, Elaine, Patterson, Scott D, Billin, Andrew, Doward, Lynda, Twiss, James, Thakker, Paresh, Derdak, Zoltan, Landgren, Henrik, Lackner, Carolin, Gouw, Annette, Hytiroglou, Prodromos, Mózes, Ferenc E, Lee, Jenny A, Alzoubi, Osama, Staufer, Katharina, Trauner, Michael, Paternostro, Rafael, Stauber, Rudolf E, van Dijk, Anne-Marieke, Mak, Anne Linde, de Saint Loup, Marc, Shima, Toshihide, Gaia, Silvia, Shalimar, Lupșor-Platon, Monica, Wong, Vincent Wai-Sun, Li, Guanlin, Wong, Grace Lai-Hung, Karlas, Thomas, Wiegand, Johannes, Sebastiani, Giada, Tsochatzis, Emmanuel, Liguori, Antonio, Yoneda, Masato, Nakajima, Atsushi, Hagström, Hannes, Akbari, Camilla, Hirooka, Masashi, Chan, Wah-Kheong, Mahadeva, Sanjiv, Rajaram, Ruveena, Zheng, Ming-Hua, George, Jacob, Eslam, Mohammed, Viganò, Mauro, Ridolfo, Sofia, Aithal, Guruprasad Padur, Lee, Dae Ho, Nasr, Patrik, Cassinotto, Christophe, de Lédinghen, Victor, Mendoza, Yuly P, Noureddin, Mazen, Truong, Emily, Harrison, Stephen A

Source: In The Lancet Gastroenterology & Hepatology August 2023 8(8):704-713

Hepatic patatin‐like phospholipase domain‐containing 3 levels are increased in I148M risk allele carriers and correlate with NAFLD in humans

Authors: Ericson, Elke, Bergenholm, Linnéa, Andréasson, Anne‐Christine, Dix, Carly I., Knöchel, Jane, Hansson, Sara F., Lee, Richard, Schumi, Jennifer, Antonsson, Madeleine, Fjellström, Ola, Nasr, Patrik, Liljeblad, Mathias, Carlsson, Björn, Kechagias, Stergios, Lindén, Daniel, Ekstedt, Mattias

Source: Hepatology communications. 6(10):2689-2701

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190647000.0x000001&indx=1&recIds=ETOCvdc_100190647000.0x000001

Non-invasive tests accurately stratify patients with NAFLD based on their risk of liver-related events

Authors: Boursier, Jerome, Hagström, Hannes, Ekstedt, Mattias, Moreau, Clemence, Bonacci, Martin, Cure, Sandrine, Ampuero, Javier, Nasr, Patrik, Tallab, Lilian, Canivet, Clémence M., Kechagias, Stergios, Sánchez, Yolanda, Dincuff, Eloise, Lucena, Ana, Roux, Marine, Riou, Jeremie, Trylesinski, Aldo, Romero-Gomez, Manuel

Source: Journal of hepatology. 76(5):1013-1020

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179671521.0x000001&indx=1&recIds=ETOCvdc_100179671521.0x000001

Low awareness of non-alcoholic fatty liver disease in patients with type 2 diabetes in Swedish Primary Health Care

Authors: Bergram, Martin, Nasr, Patrik, Iredahl, Fredrik, Kechagias, Stergios, Rådholm, Karin, Ekstedt, Mattias

Source: Scandinavian journal of gastroenterology. 57(1):60-69

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138856867.0x000001&indx=1&recIds=ETOCvdc_100138856867.0x000001

Effect of common genetic variants on the risk of cirrhosis in non‐alcoholic fatty liver disease during 20 years of follow‐up

Authors: Holmer, Magnus, Ekstedt, Mattias, Nasr, Patrik, Zenlander, Robin, Wester, Axel, Tavaglione, Federica, Romeo, Stefano, Kechagias, Stergios, Stål, Per, Hagström, Hannes

Source: Liver international. 42(12):2769-2780

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168408928.0x000001&indx=1&recIds=ETOCvdc_100168408928.0x000001

Repeated measurements of non‐invasive fibrosis tests to monitor the progression of non‐alcoholic fatty liver disease: A long‐term follow‐up study

Authors: Balkhed, Wile, Åberg, Fredrik O., Nasr, Patrik, Ekstedt, Mattias, Kechagias, Stergios

Source: Liver international. 42(7):1545-1556

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154068140.0x000001&indx=1&recIds=ETOCvdc_100154068140.0x000001

Risk for hepatic and extra‐hepatic outcomes in nonalcoholic fatty liver disease

Authors: Hagström, Hannes, Kechagias, Stergios, Ekstedt, Mattias

Source: Journal of internal medicine. 292(2):177-189

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157096513.0x000001&indx=1&recIds=ETOCvdc_100157096513.0x000001

Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance

Authors: Clark, James, Cordell, Heather J., Darlay, Rebecca, Day, Christopher P., Hardy, Tim, Liu, Yang-Lin, Oakley, Fiona, Palmer, Jeremy, Queen, Rachel, Wonders, Kristy, Bossuyt, Patrick M., Holleboom, Adriaan G., Zafarmand, Hadi, Vali, Yasaman, Lee, Jenny, Clement, Karine, Pais, Raluca, Schuppan, Detlef, Allison, Michael, Cuenca, Sergio Rodriguez, Pellegrinelli, Vanessa, Vacca, Michele, Vidal-Puig, Antonio, Hyötyläinen, Tuulia, McGlinchey, Aidan, Orešič, Matej, Sen, Partho, Mato, Jose, Millet, Óscar, Dufour, Jean-Francois, Harrison, Stephen, Neubauer, Stefan, Pavlides, Michael, Mozes, Ferenc, Akhtar, Salma, Banerjee, Rajarshi, Kelly, Matt, Shumbayawonda, Elizabeth, Dennis, Andrea, Erpicum, Charlotte, Romero-Gomez, Manuel, Gallego-Durán, Rocío, Fernández, Isabel, Karsdal, Morten, Leeming, Diana, Fisker, Mette Juul, Erhardtsen, Elisabeth, Rasmussen, Daniel, Qvist, Per, Sinisi, Antonia, Sandt, Estelle, Tonini, Maria Manuela, Parola, Maurizio, Rosso, Chiara, Marra, Fabio, Gastaldelli, Amalia, Francque, Sven, Kechagias, Stergios, Yki-Järvinen, Hannele, Porthan, Kimmo, van Mil, Saskia, Papatheodoridis, George, Cortez-Pinto, Helena, Valenti, Luca, Petta, Salvatore, Miele, Luca, Geier, Andreas, Trautwein, Christian, Hockings, Paul, Newsome, Phil, Wenn, David, Pereira Rodrigues, Cecília Maria, Hanf, Rémy, Chaumat, Pierre, Rosenquist, Christian, Trylesinski, Aldo, Ortiz, Pablo, Duffin, Kevin, Yunis, Carla, Miller, Melissa, Tuthill, Theresa, Ertle, Judith, Younes, Ramy, Alexander, Leigh, Ostroff, Rachel, Kjær, Mette Skalshøi, Mikkelsen, Lars Friis, Brass, Clifford, Jennings, Lori, Balp, Maria-Magdalena, Martic, Miljen, Hanauer, Guido, Shankar, Sudha, Torstenson, Richard, Fournier, Céline, Ehman, Richard, Kalutkiewicz, Michael, Pepin, Kay, Myers, Joel, Shevell, Diane, Ho, Gideon, Landgren, Henrik, Myers, Rob, Doward, Lynda, Whalley, Diane, Twiss, James, Johnson, Katherine, Leary, Peter J., Govaere, Olivier, Barter, Matthew J., Charlton, Sarah H., Cockell, Simon J., Tiniakos, Dina, Zatorska, Michalina, Bedossa, Pierre, Brosnan, M. Julia, Cobbold, Jeremy F., Ekstedt, Mattias, Aithal, Guruprasad P., Clément, Karine, Schattenberg, Jörn M., Boursier, Jerome, Ratziu, Vlad, Bugianesi, Elisabetta, Anstee, Quentin M., Daly, Ann K.

Source: In JHEP Reports February 2022 4(2)

Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis

Authors: Anstee, Quentin, Daly, Ann, Johnson, Katherine, Govaere, Olivier, Cockell, Simon, Tiniakos, Dina, Bedossa, Pierre, Oakley, Fiona, Cordell, Heather, Day, Chris, Wonders, Kristy, Bossuyt, Patrick, Zafarmand, Hadi, Vali, Yasaman, Lee, Jenny, Ratziu, Vlad, Clement, Karine, Pais, Raluca, Schuppan, Detlef, Schattenberg, Jörn, Vidal-Puig, Toni, Vacca, Michele, Rodrigues-Cuenca, Sergio, Allison, Mike, Kamzolas, Ioannis, Petsalaki, Evangelia, Oresic, Matej, Hyötyläinen, Tuulia, McGlinchey, Aiden, Mato, Jose M., Millet, Oscar, Dufour, Jean-François, Berzigotti, Annalisa, Pavlides, Michael, Harrison, Stephen, Neubauer, Stefan, Cobbold, Jeremy, Mozes, Ferenc, Akhtar, Salma, Banerjee, Rajarshi, Kelly, Matt, Shumbayawonda, Elizabeth, Dennis, Andrea, Erpicum, Charlotte, Romero-Gómez, Manuel, Gómez-González, Emilio, Ampuero, Javier, Castell, Javier, Gallego-Durán, Rocío, Fernández, Isabel, Montero-Vallejo, Rocío, Karsdal, Morten, Erhardtsen, Elisabeth, Rasmussen, Daniel, Leeming, Diana Julie, Fisker, Mette Juul, Sinisi, Antonia, Musa, Kishwar, Betsou, Fay, Sandt, Estelle, Tonini, Manuela, Bugianesi, Elisabetta, Rosso, Chiara, Armandi, Angelo, Marra, Fabio, Gastaldelli, Amalia, Svegliati, Gianluca, Boursier, Jérôme, Francque, Sven, Vonghia, Luisa, Ekstedt, Mattias, Kechagias, Stergios, Yki-Jarvinen, Hannele, Luukkonen, Panu, van Mil, Saskia, Papatheodoridis, George, Cortez-Pinto, Helena, Valenti, Luca, Petta, Salvatore, Miele, Luca, Geier, Andreas, Trautwein, Christian, Aithal, Guru, Hockings, Paul, Newsome, Philip, Wenn, David, Pereira Rodrigues, Cecília Maria, Chaumat, Pierre, Hanf, Rémy, Trylesinski, Aldo, Ortiz, Pablo, Duffin, Kevin, Brosnan, Julia, Tuthill, Theresa, McLeod, Euan, Ertle, Judith, Younes, Ramy, Ostroff, Rachel, Alexander, Leigh, Kjær, Mette Skalshøi, Mikkelsen, Lars Friis, Balp, Maria-Magdalena, Brass, Clifford, Jennings, Lori, Martic, Miljen, Loeffler, Juergen, Hanauer, Guido, Shankar, Sudha, Fournier, Céline, Pepin, Kay, Ehman, Richard, Myers, Joel, Ho, Gideon, Torstenson, Richard, Myers, Rob, Doward, Lynda, Selvaraj, Emmanuel Anandraj, Mózes, Ferenc Emil, Jayaswal, Arjun Narayan Ajmer, Zafarmand, Mohammad Hadi, Lee, Jenny A., Levick, Christina Kim, Young, Liam Arnold Joseph, Palaniyappan, Naaventhan, Liu, Chang-Hai, Aithal, Guruprasad Padur, Brosnan, M. Julia, Tuthill, Theresa A., Anstee, Quentin M., Harrison, Stephen A., Bossuyt, Patrick M.

Source: In Journal of Hepatology October 2021 75(4):770-785

Low hepatic manganese concentrations in patients with hepatic steatosis – A cohort study of copper, iron and manganese in liver biopsies

Authors: Nasr, Patrik ^*, Ignatova, Simone, Lundberg, Peter, Kechagias, Stergios, Ekstedt, Mattias

Source: In Journal of Trace Elements in Medicine and Biology September 2021 67

A pilot study of golexanolone, a new GABA-A receptor-modulating steroid antagonist, in patients with covert hepatic encephalopathy

Authors: Montagnese, Sara, Lauridsen, Mette, Vilstrup, Hendrik, Zarantonello, Lisa, Lakner, Géza, Fitilev, Sergey, Zupanets, Igor, Kozlova, Irina, Bunkova, Elena, Tomasiewicz, Krzysztof, Berglund, Jan Erik, Rorsman, Fredrik, Hagström, Hannes, Kechagias, Stergios, Ocklind, Carin Edmark, Mauney, Joe, Thunarf, Fredrik, Mokhatarani, Masoud, Bäckström, Torbjörn, Doverskog, Magnus, Lins, Lars-Erik, Månsson, Maria, Samuelson, Per, Nilsson, Dag, Schalling, Martin, Johansson, Maja, Arlander, Eva, Scharschmidt, Bruce F.

Source: In Journal of Hepatology July 2021 75(1):98-107

Non-alcoholic fatty liver disease does not increase dementia risk although histology data might improve risk prediction

Authors: Shang, Ying, Nasr, Patrik, Ekstedt, Mattias, Widman, Linnea, Stål, Per, Hultcrantz, Rolf, Kechagias, Stergios, Hagström, Hannes

Source: In JHEP Reports April 2021 3(2)

Review article: non‐alcoholic fatty liver disease and cardiovascular diseases: associations and treatment considerations

Authors: Polyzos, Stergios A., Kechagias, Stergios, Tsochatzis, Emmanuel A.

Source: Alimentary pharmacology & therapeutics. 54(8):1013-1025

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132302435.0x000001&indx=1&recIds=ETOCvdc_100132302435.0x000001