Mechanism of immune activation mediated by genomic instability and its implication in radiotherapy combined with immune checkpoint inhibitors

Authors: Wang, Si-Wei, Zheng, Qiu-Yi, Hong, Wei-Feng, Tang, Bu-Fu, Hsu, Shu-Jung, Zhang, Yang, Zheng, Xiao-Bin, Zeng, Zhao-Chong, Gao, Chao, Ke, Ai-Wu, Du, Shi-Suo

Source: In Radiotherapy and Oncology October 2024 199

Autophagy suppression facilitates macrophage M2 polarization via increased instability of NF-κB pathway in hepatocellular carcinoma

Authors: Gao, Zheng ^{a, b, 1}, Li, Xiao–Gang ^{a, b, 1}, Feng, Shan-Ru ^{a, b, 1}, Chen, Jia–Feng ^{a, b}, Song, Kang ^{a, b}, Shi, Ying–Hong ^{a, b}, Tang, Zheng ^{a, b}, Liu, Wei–Ren ^{a, b}, Zhang, Xin ^{a, b}, Huang, Ao ^{a, b}, Luo, Xuan–Ming ^c, Zeng, Hai-Ying ^e, Gao, Qiang ^{a, b}, Shi, Guo–Ming ^{a, b}, Ke, Ai–Wu ^{a, b}, Zhou, Jian ^{a, b, d}, Fan, Jia ^{a, b, d, ⁎}, Fu, Xiu–Tao ^{a, b, ⁎}, Ding, Zhen–Bin ^{a, b, c, f, ⁎}

Source: In International Immunopharmacology October 2023 123

WDR4/TRIM28 is a novel molecular target linked to lenvatinib resistance that helps retain the stem characteristics in hepatocellular carcinomas

Authors: Han, Wei-yu, Wang, Jie, Zhao, Jing, Zheng, Yi-min, Chai, Xiao-qiang, Gao, Chao, Cai, Jia-bin, Ke, Ai-wu, Fan, Jia, Gao, Ping-ting, Sun, Hai-xiang

Source: In Cancer Letters 1 August 2023 568

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy

Authors: Dong, Zhao-Ru, Cai, Jia-Bin, Shi, Guo-Ming, Yang, Ya-Fei, Huang, Xiao-Yong, Zhang, Chi, Dong, Rui-Zhao, Wei, Chuan-Yuan, Li, Tao, Ke, Ai-Wu, Fan, Jia

Source: In Cancer Letters 28 June 2023 564

Inhibition of autophagy in macrophage promotes IL-1β-mediated hepatocellular carcinoma progression via inflammasome accumulation and self-recruitment

Authors: Gao, Zheng, Feng, Shan-Ru, Chen, Jia‑Feng, Li, Xiao‑Gang, Shi, Ying‑Hong, Tang, Zheng, Liu, Wei‑Ren, Zhang, Xin, Huang, Ao, Luo, Xuan‑Ming, Zeng, Hai-Ying, Gao, Qiang, Shi, Guo‑Ming, Ke, Ai‑Wu, Zhou, Jian, Fan, Jia, Fu, Xiu‑Tao, Ding, Zhen‑Bin

Source: In Biomedicine & Pharmacotherapy May 2023 161

PKCα/ZFP64/CSF1 axis resets the tumor microenvironment and fuels anti-PD1 resistance in hepatocellular carcinoma

Authors: Wei, Chuan-Yuan, Zhu, Meng-Xuan, Zhang, Peng-Fei, Huang, Xiao-Yong, Wan, Jin-Kai, Yao, Xiu-Zhong, Hu, Ze-Tao, Chai, Xiao-Qiang, Peng, Rui, Yang, Xuan, Gao, Chao, Gao, Jian, Wang, Si-Wei, Zheng, Yi-Min, Tang, Zheng, Gao, Qiang, Zhou, Jian, Fan, Jia-Bin, Ke, Ai-Wu, Fan, Jia

Source: Journal of hepatology. 77(1):163-176

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165884410.0x000001&indx=1&recIds=ETOCvdc_100165884410.0x000001

Application of a single-cell-RNA-based biological-inspired graph neural network in diagnosis of primary liver tumors.

Authors: Zhang, Dao-Han, Liang, Chen, Hu, Shu-Yang, Huang, Xiao-Yong, Yu, Lei, Meng, Xian-Long, Guo, Xiao-Jun, Zeng, Hai-Ying, Chen, Zhen, Zhang, Lv, Pei, Yan-Zi, Ye, Mu, Cai, Jia-Bin, Huang, Pei-Xin, Shi, Ying-Hong, Ke, Ai-Wu, Chen, Yi, Ji, Yuan, Shi, Yujiang Geno, Zhou, Jian

Source: Journal of Translational Medicine; 10/1/2024, Vol. 22 Issue 1, p1-15, 15p

Subject Terms: GRAPH neural networks, LIVER tumors, BENIGN tumors, TUMOR microenvironment, CELL communication

Spatial and temporal clonal evolution of intrahepatic cholangiocarcinoma

Authors: Dong, Liang-Qing, Shi, Yang, Ma, Li-Jie, Yang, Liu-Xiao, Wang, Xiao-Ying, Zhang, Shu, Wang, Zhi-Chao, Duan, Meng, Zhang, Zhao, Liu, Long-Zi, Zheng, Bo-Hao, Ding, Zhen-Bin, Ke, Ai-Wu, Gao, Da-Ming, Yuan, Ke, Zhou, Jian, Fan, Jia, Xi, Ruibin, Gao, Qiang

Source: In Journal of Hepatology July 2018 69(1):89-98

Corrigendum to: 'PKCα/ZFP64/CSF1 axis resets the tumor microenvironment and fuels anti-PD1 resistance in hepatocellular carcinoma' [J Hepatol 77 (2022) 163-176]

Authors: Wei, Chuan-Yuan, Zhu, Meng-Xuan, Zhang, Peng-Fei, Huang, Xiao-Yong, Wan, Jin-Kai, Yao, Xiu-Zhong, Hu, Ze-Tao, Chai, Xiao-Qiang, Peng, Rui, Yang, Xuan, Gao, Chao, Gao, Jian, Wang, Si-Wei, Zheng, Yi-Min, Tang, Zheng, Gao, Qiang, Zhou, Jian, Cai, Jia-Bin, Ke, Ai-Wu, Fan, Jia

Source: Journal of hepatology. 78(4):881-882

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186188370.0x000001&indx=1&recIds=ETOCvdc_100186188370.0x000001

LncRNA SNHG3 induces EMT and sorafenib resistance by modulating the miR‐128/CD151 pathway in hepatocellular carcinoma

Authors: Zhang, Peng‐Fei, Wang, Fei, Wu, Jing, Wu, Yin, Huang, Wei, Liu, Dong, Huang, Xiao‐Yong, Zhang, Xue‐Mei, Ke, Ai‐Wu

Source: Journal of cellular physiology. 234(3):2788-2794

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136041646.0x000001&indx=1&recIds=ETOCvdc_100136041646.0x000001

The long noncoding RNA NORAD enhances the TGF‐β pathway to promote hepatocellular carcinoma progression by targeting miR‐202‐5p

Authors: Yang, Xuan, Cai, Jia‐Bin, Peng, Rui, Wei, Chuan‐Yuan, Lu, Jia‐Cheng, Gao, Chao, Shen, Zhao‐Zuo, Zhang, Peng‐Fei, Huang, Xiao‐Yong, Ke, Ai‐Wu, Shi, Guo‐Ming, Fan, Jia

Source: Journal of cellular physiology. 234(7):12051-12060

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100133039543.0x000001&indx=1&recIds=ETOCvdc_100133039543.0x000001

Predicting overall survival of patients with hepatocellular carcinoma using a three‐category method based on DNA methylation and machine learning

Authors: Dong, Rui‐Zhao, Yang, Xuan, Zhang, Xin‐Yu, Gao, Ping‐Ting, Ke, Ai‐Wu, Sun, Hui‐chuan, Zhou, Jian, Fan, Jia, Cai, Jia‐bin, Shi, Guo‐Ming

Source: Journal of cellular and molecular medicine. 23(5):3369-3374

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090567668.0x000001&indx=1&recIds=ETOCvdc_100090567668.0x000001

Lymphoid‐specific helicase promotes the growth and invasion of hepatocellular carcinoma by transcriptional regulation of centromere protein F expression

Authors: Yang, Xuan, Miao, Bi‐Si, Wei, Chuan‐Yuan, Dong, Rui‐Zhao, Gao, Ping‐Ting, Zhang, Xin‐Yu, Lu, Jia‐Cheng, Gao, Chao, Wang, Xiao‐Ying, Sun, Hui‐Chuan, Zhou, Jian, Fan, Jia, Ke, Ai‐Wu, Shi, Guo‐Ming, Cai, Jia‐Bin

Source: Cancer science. 110(7):2133-2144

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085014871.0x000001&indx=1&recIds=ETOCvdc_100085014871.0x000001

Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

Authors: Zhang, Peng-Fei, Wei, Chuan-Yuan, Huang, Xiao-Yong, Peng, Rui, Yang, Xuan, Lu, Jia-Cheng, Zhang, Chi, Gao, Chao, Cai, Jia-Bin, Gao, Ping-Ting, Gao, Dong-Mei, Shi, Guo-Ming, Ke, Ai-Wu, Fan, Jia

Source: Molecular cancer. 18(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188478322.0x000001&indx=1&recIds=ETOCvdc_100188478322.0x000001

Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma

Authors: Peng, Rui, Zhang, Peng-Fei, Yang, Xuan, Wei, Chuan-Yuan, Huang, Xiao-Yong, Cai, Jia-Bin, Lu, Jia-Cheng, Gao, Chao, Sun, Hai-Xiang, Gao, Qiang, Bai, Dou-Sheng, Shi, Guo-Ming, Ke, Ai-Wu, Fan, Jia

Source: Journal of experimental & clinical cancer research. 38(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185874954.0x000001&indx=1&recIds=ETOCvdc_100185874954.0x000001

Correction: Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis.

Authors: Huang, Xiao-Yong, Zhang, Peng-Fei, Wei, Chuan-Yuan, Peng, Rui, Lu, Jia-Cheng, Gao, Chao, Cai, Jia-Bing, Yang, Xuan, Fan, Jia, Ke, Ai-Wu, Zhou, Jian, Shi, Guo-Ming

Source: Molecular Cancer; 2/29/2024, Vol. 23 Issue 1, p1-4, 4p

Subject Terms: CIRCULAR RNA, IMMUNOSUPPRESSION, HEPATOCELLULAR carcinoma

Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma

Authors: Xie, Nan, Cai, Jia-Bin, Zhang, Lu, Zhang, Peng-Fei, Shen, Ying-Hao, Yang, Xuan, Lu, Jia-Cheng, Gao, Dong-Mei, Kang, Qiang, Liu, Li-Xin, Zhang, Chi, Huang, Xiao-Yong, Zou, Hao, Zhang, Xin-Yu, Song, Zheng-Ji, Sun, Hai-Xiang, Fu, Bi-Mang, Ke, Ai-Wu, Shi, Guo-Ming

Source: Cell death and disease. 8(12):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099958869.0x000001&indx=1&recIds=ETOCvdc_100099958869.0x000001

CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity.

Authors: Dong, Zhao-Ru^1,2,3 (AUTHOR), Ke, Ai-Wu^1,2 (AUTHOR), Li, Tao³ (AUTHOR), Cai, Jia-Bing^1,2 (AUTHOR), Yang, Ya-fei³ (AUTHOR), Zhou, Wei^1,2 (AUTHOR), Shi, Guo-Ming^1,2 (AUTHOR) shi.guoming@zs-hospital.sh.cn, Fan, Jia^1,2,4 (AUTHOR) fanjia-zs@outlook.com

Source: Molecular Cancer. 5/13/2021, Vol. 20 Issue 1, p1-16. 16p.

Subject Terms: *HEPATOCELLULAR carcinoma, *SORAFENIB, *METHYLATION, *CIRCULAR RNA, *PROGRESSION-free survival

Erratum: CCL15 recruits suppressive monocytes to facilitate immune escape and disease progression in hepatocellular carcinoma.

Authors: Liu, Long-Zi, Zhang, Zhao, Zheng, Bo-Hao, Shi, Yang, Duan, Men, Ma, Li-Jie, Wang, Zhi-Chao, Dong, Liang-Qing, Dong, Ping-Ping, Shi, Jie-Yi, Zhang, Shu, Ding, Zhen-Bin, Ke, Ai-Wu, Cao, Ya, Zhang, Xiao-Ming, Xi, Ruibin, Zhou, Jian, Fan, Jia, Wang, Xiao-Ying, Gao, Qiang

Source: Hepatology (02709139); Mar2025, Vol. 81 Issue 3, pE113-E114, 2p

Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients

Authors: Gao, Qiang, Zhao, Ying–Jun, Wang, Xiao–Ying, Guo, Wei–Jie, Gao, Song, Wei, Lin, Shi, Jie–Yi, Shi, Guo–Ming, Wang, Zhi–Chao, Zhang, Yuan–Nv, Shi, Ying–Hong, Ding, Jie, Ding, Zhen–Bin, Ke, Ai–Wu, Dai, Zhi, Wu, Fei–Zhen, Wang, Hui, Qiu, Zhao–Ping, Chen, Zhi–Ao, Zhang, Zhen–Feng, Qiu, Shuang–Jian, Zhou, Jian, He, Xiang–Huo, Fan, Jia

Source: In Gastroenterology May 2014 146(5):1397-1407