P473: CRISPR/CAS9 GENE EDITING CLARIFIES THE ROLE OF CD33 SNP RS12459419 IN GEMTUZUMAB OZOGAMICIN-MEDIATED CYTOTOXICITY

Authors: Shuki Oya, Hidetoshi Ozawa, Takayuki Nakamura, Yoshimi Maehiro, Yusuke Takaki, Yoshinobu Fukuyama, Yoshitaka Yamasaki, Maki Yamaguchi, Kazutoshi Aoyama, Fumihiko Mouri, Koji Nagafuji

Source: HemaSphere, Vol 7, p e53072ea (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000968800.53072.ea; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/66b41367bcc84ceea53108b134a79bc7

Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia: A Case Report

Authors: Sho Mitsumune, Yasuhiro Manabe, Taijun Yunoki, Shyoichiro Kono, Kazutoshi Aoyama, Yoko Shinno, Hisashi Narai, Koji Abe

Source: Case Reports in Neurology, Vol 10, Iss 1, Pp 108-111 (2018)

Subject Terms: Polymyositis, Myasthenia gravis, Aplastic anemia, Bone marrow transplantation, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/488476; https://doaj.org/toc/1662-680X

Access URL: https://doaj.org/article/cf3218509dd441be89461b7acb08e29d

Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease

Authors: Satomi Matsuoka, Daigo Hashimoto, Masanori Kadowaki, Hiroyuki Ohigashi, Eiko Hayase, Emi Yokoyama, Yuta Hasegawa, Takahiro Tateno, Xuanzhong Chen, Kazutoshi Aoyama, Hideyo Oka, Masahiro Onozawa, Kiyoshi Takeda, Koichi Akashi, Takanori Teshima

Source: Haematologica, Vol 105, Iss 1 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9492; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/ccd944044c6c4e4db443ee24cd88437a

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

Authors: Saha, Asim, O'Connor, Roddy S., Thangavelu, Govindarajan, Lovitch, Scott B., Dandamudi, Durga Bhavani, Wilson, Caleph B., Vincent, Benjamin G., Tkachev, Victor, Pawlicki, Jan M., Furlan, Scott N., Kean, Leslie S., Kazutoshi Aoyama, Taylor, Patricia A., Panoskaltsis-Mortari, Angela, Foncea, Rocio, Ranganathan, Parvathi, Devine, Steven M., Burrill, Joel S., Lili Guo, Sacristan, Catarina

Source: Journal of Clinical Investigation. Jul2016, Vol. 126 Issue 7, p2642-2660. 19p. 1 Diagram, 10 Graphs.

Subjects: LIGANDS (Biochemistry), GRAFT versus host disease, T cells, APOPTOSIS, GLYCOLYSIS, BIOENERGETICS, GENETICS, THERAPEUTICS, GLUTAMINE metabolism, ANIMALS, ANTIGENS, BONE marrow, BONE marrow transplantation, CELLULAR signal transduction, CYTOKINES, GLUCOSE, INFLAMMATION, MICE, OXYGEN, PHOSPHORYLATION, TREATMENT effectiveness, MONONUCLEAR leukocytes