Development and validation of a population pharmacokinetic model of vancomycin for patients of advanced age

Authors: Keisuke Takada, Masaru Samura, Yuki Igarashi, Ayako Suzuki, Tomoyuki Ishigo, Satoshi Fujii, Yuta Ibe, Hiroaki Yoshida, Hiroaki Tanaka, Fumiya Ebihara, Takumi Maruyama, Yukihiro Hamada, Toshiaki Komatsu, Atsushi Tomizawa, Akitoshi Takuma, Hiroaki Chiba, Yusuke Yagi, Yoshifumi Nishi, Yuki Enoki, Kazuaki Taguchi, Koji Tanikawa, Hiroyuki Kunishima, Kazuaki Matsumoto

Source: Journal of Pharmaceutical Health Care and Sciences, Vol 11, Iss 1, Pp 1-10 (2025)

Subject Terms: Patients of advanced age, Population pharmacokinetics, Serum albumin, Vancomycin, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://doaj.org/toc/2055-0294

Access URL: https://doaj.org/article/6b09cead7367495eabf7688df0c38aac

In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

Authors: Kengo Hayashi, Masahiro Suzuki, Yoshikazu Ishii, Yasufumi Matsumura, Kazuaki Matsumoto, Sho Saito, Yohei Doi

Source: Journal of Global Antimicrobial Resistance, Vol 42, Iss , Pp 73-79 (2025)

Subject Terms: Aztreonam, Relebactam, Metallo-β-lactamase, Serine‑β-lactamase, Carbapenemase-producing pathogens, Co-producers, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213716525000396; https://doaj.org/toc/2213-7165

Access URL: https://doaj.org/article/9ae0a68acbeb4de4b9b71e86d976fd14

Investigating the hypothermic effects of fluoroquinolone antimicrobials on non-bacterial fever model mice

Authors: Ryohei Hara, Kazuaki Taguchi, Hiromi Ogino, Yuko Okamoto, Yuki Enoki, Junko Kizu, Seiji Hori, Kazuaki Matsumoto

Source: Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-6 (2024)

Subject Terms: Fluoroquinolone, Hypothermia, Fever, Mice, Glucocorticoid, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://doaj.org/toc/2055-0294

Access URL: https://doaj.org/article/be0dbc2a8686489bbb47e5318e90344e

Reply to Mitsuboshi, 'Enhancing result reliability by addressing potential confounding factors'

Authors: Tomoyuki Ishigo, Kazuaki Matsumoto, Hiroaki Yoshida, Hiroaki Tanaka, Yuta Ibe, Satoshi Fujii, Masahide Fukudo, Hisato Fujihara, Fumihiro Yamaguchi, Fumiya Ebihara, Takumi Maruyama, Yukihiro Hamada, Masaru Samura, Fumio Nagumo, Toshiaki Komatsu, Atsushi Tomizawa, Akitoshi Takuma, Hiroaki Chiba, Yoshifumi Nishi, Yuki Enoki, Kazuaki Taguchi, Ayako Suzuki

Source: Microbiology Spectrum, Vol 13, Iss 3 (2025)

Subject Terms: vancomycin, therapeutic drug monitoring, nephrotoxicity, area under the concentration–time curve, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/53c0547ee5844608a358b3fb7cbaf3d5

Relationship between nephrotoxicity and area under the concentration–time curve of vancomycin in critically ill patients: a multicenter retrospective study

Authors: Tomoyuki Ishigo, Kazuaki Matsumoto, Hiroaki Yoshida, Hiroaki Tanaka, Yuta Ibe, Satoshi Fujii, Masahide Fukudo, Hisato Fujihara, Fumihiro Yamaguchi, Fumiya Ebihara, Takumi Maruyama, Yukihiro Hamada, Masaru Samura, Fumio Nagumoi, Toshiaki Komatsu, Atsushi Tomizawa, Akitoshi Takuma, Hiroaki Chiba, Yoshifumi Nishi, Yuki Enoki, Kazuaki Taguchi, Ayako Suzuki

Source: Microbiology Spectrum, Vol 12, Iss 7 (2024)

Subject Terms: vancomycin, therapeutic drug monitoring, nephrotoxicity, area under the concentration–time curve, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/3e2fa47cfe994d61a837e4c15a084d4b

Model‐informed precision dosing of vancomycin for rapid achievement of target area under the concentration‐time curve: A simulation study

Authors: Kazutaka Oda, Tomoyuki Yamada, Kazuaki Matsumoto, Yuki Hanai, Takashi Ueda, Masaru Samura, Akari Shigemi, Hirofumi Jono, Hideyuki Saito, Toshimi Kimura

Source: Clinical and Translational Science, Vol 16, Iss 11, Pp 2265-2275 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/ea99879e4cce437aa35fd73f303a4d9f

A combination of 5/6‐nephrectomy and unilateral ureteral obstruction model accelerates progression of remote organ fibrosis in chronic kidney disease

Authors: Kyoka Homma, Yuki Enoki, Sato Uchida, Kazuaki Taguchi, Kazuaki Matsumoto

Source: FASEB BioAdvances, Vol 5, Iss 10, Pp 377-394 (2023)

Subject Terms: extrarenal tissue, fibrosis, chronic kidney disease, indoxyl sulfate, transforming growth factor‐β, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2573-9832

Access URL: https://doaj.org/article/6c91211037d04949aba8e5734af143d1

A Bcl11bN797K variant isolated from an immunodeficient patient inhibits early thymocyte development in mice

Authors: Kazuaki Matsumoto, Kazuki Okuyama, Tom Sidwell, Motoi Yamashita, Takaho Endo, Naoko Satoh-Takayama, Hiroshi Ohno, Tomohiro Morio, Ellen V. Rothenberg, Ichiro Taniuchi

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: IEIS, immune deficiency, BCL11B, mis-sense variant, T cell, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1363704/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/83c8db04a2b14d88adbf03ead9999ff0

Polyoxazoline-conjugated porcine serum albumin as an artificial plasma expander for dogs

Authors: Wataru Okamoto, Tomone Usui, Mai Hasegawa, Tatsuhiro Kobayashi, Junya Fujisawa, Kazuaki Taguchi, Kazuaki Matsumoto, Mitsutomo Kohno, Masayuki Iwazaki, Shotaro Shimano, Itsuma Nagao, Hiroto Toyoda, Naoki Matsumura, Hirotaka Tomiyasu, Ryota Tochinai, Teruyuki Komatsu

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e265ef0d2d004cd0bc6c462a06f60241

Model‐informed precision dosing of teicoplanin for the rapid achievement of the target area under the concentration‐time curve: A simulation study

Authors: Kazutaka Oda, Tomoyuki Yamada, Kazuaki Matsumoto, Yuki Hanai, Takashi Ueda, Masaru Samura, Akari Shigemi, Hirofumi Jono, Hideyuki Saito, Toshimi Kimura

Source: Clinical and Translational Science, Vol 16, Iss 4, Pp 704-713 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/41106ad7cbd9431e91552991593c2fc4

The G protein‐coupled receptor ligand apelin‐13 ameliorates skeletal muscle atrophy induced by chronic kidney disease

Authors: Yuki Enoki, Tomoya Nagai, Yuna Hamamura, Sumika Osa, Hideaki Nakamura, Kazuaki Taguchi, Hiroshi Watanabe, Toru Maruyama, Kazuaki Matsumoto

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 553-564 (2023)

Subject Terms: apelin, Apj, chronic kidney disease, elabela, skeletal muscle atrophy, uraemic toxin, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/f562201351f84f9dbb69927c167136a4

Safety of linezolid in patients with decreased renal function and trough monitoring: a systematic review and meta-analysis

Authors: Xiaoxi Liu, Mari Aoki, Sumika Osa, Chihiro Ito, Reika Saiki, Tomoya Nagai, Yuki Enoki, Kazuaki Taguchi, Kazuaki Matsumoto

Source: BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-20 (2022)

Subject Terms: Linezolid, Hematological toxicity, Thrombocytopenia, Renal, Trough concentrations, Therapeutics. Pharmacology, RM1-950, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: https://doaj.org/toc/2050-6511

Access URL: https://doaj.org/article/deb698760ab34427945a148037d58547

Analysis of adverse drug events in pulmonary Mycobacterium avium complex disease using spontaneous reporting system

Authors: Takuya Ozawa, Ho Namkoong, Risako Takaya, Yusuke Takahashi, Koichi Fukunaga, Yuki Enoki, Kazuaki Taguchi, Junko Kizu, Kazuaki Matsumoto, Naoki Hasegawa

Source: BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-8 (2022)

Subject Terms: Mycobacterium avium complex (MAC), Adverse events, Clarithromycin, Ethambutol, Rifampicin, Reporting odds ratio, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/ac3fec8292de4e87910e19874001e2dd

Neurotoxicity associated with colistin methanesulfonate treatment is enhanced by concomitant sevoflurane inhalation

Authors: Mai Gotoda, Yuki Enoki, Shino Shishido, Kazuaki Taguchi, Kazuaki Matsumoto

Source: Toxicology Reports, Vol 9, Iss , Pp 1255-1260 (2022)

Subject Terms: Colistin methanesulfonate, Colistin, Neurotoxicity, Sevoflurane, Ganglionic blocking, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750022001342; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/d6de597bcb954c30aec5ac09dcd0160d

Candidates for area under the concentration–time curve (AUC)-guided dosing and risk reduction based on analyses of risk factors associated with nephrotoxicity in vancomycin-treated patients

Authors: Naoto Hashimoto, Toshimi Kimura, Yukihiro Hamada, Takashi Niwa, Yuki Hanai, Masayuki Chuma, Satoshi Fujii, Kazuaki Matsumoto, Akari Shigemi, Hideki Kawamura, Yoshiko Takahashi, Yoshio Takesue

Source: Journal of Global Antimicrobial Resistance, Vol 27, Iss , Pp 12-19 (2021)

Subject Terms: Vancomycin, Nephrotoxicity, Acute kidney injury, Area under the concentration–time curve, AUC, Therapeutic drug monitoring, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213716521001880; https://doaj.org/toc/2213-7165

Access URL: https://doaj.org/article/8c3cb8250356435498852833f300730b

Pharmacokinetic/pharmacodynamic evaluation of teicoplanin against Staphylococcus aureus in a murine thigh infection model

Authors: Erika Watanabe, Kazuaki Matsumoto, Kazuro Ikawa, Yuta Yokoyama, Akari Shigemi, Yuki Enoki, Yasuhiro Umezaki, Koyo Nakamura, Keiichiro Ueno, Hideyuki Terazono, Norifumi Morikawa, Yasuo Takeda

Source: Journal of Global Antimicrobial Resistance, Vol 24, Iss , Pp 83-87 (2021)

Subject Terms: Teicoplanin, Methicillin-resistant Staphylococcus aureus, Methicillin-susceptible Staphylococcus aureus, Pharmacokinetics/pharmacodynamics, Neutropenic murine thigh infection model, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213716520303003; https://doaj.org/toc/2213-7165

Access URL: https://doaj.org/article/074a031110824a18ab1ea363f3b857a3

The monitoring of vancomycin: a systematic review and meta-analyses of area under the concentration-time curve-guided dosing and trough-guided dosing

Authors: Moeko Tsutsuura, Hiromu Moriyama, Nana Kojima, Yuki Mizukami, Sho Tashiro, Sumika Osa, Yuki Enoki, Kazuaki Taguchi, Kazutaka Oda, Satoshi Fujii, Yoshiko Takahashi, Yukihiro Hamada, Toshimi Kimura, Yoshio Takesue, Kazuaki Matsumoto

Source: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021)

Subject Terms: Vancomycin, Trough, AUC, Nephrotoxicity, Meta-analysis, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/8ed0fa5611b2497f8e6f1a95a9efb213

Stability of antimicrobial agents in an elastomeric infusion pump used for outpatient parenteral antimicrobial therapy

Authors: Mutsumi Akahane, Yuki Enoki, Reika Saiki, Yukitaka Hayashi, Kana Hiraoka, Kyoka Honma, Marina Itagaki, Mai Gotoda, Kozue Shinoda, Satomi Hanyu, Yuna Hamamura, Taichi Miyajima, Chihiro Ito, Kazuaki Taguchi, Shunsuke Uno, Yoshifumi Uwamino, Osamu Iketani, Naoki Hasegawa, Kazuaki Matsumoto

Source: International Journal of Infectious Diseases, Vol 103, Iss , Pp 464-468 (2021)

Subject Terms: Outpatient parenteral antimicrobial therapy, Elastomeric infusion pump, Cefazolin, Cefmetazole, piperacillin/tazobactam, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971220324899; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/8d862d177fd24687a1dccba6b18b299b

Semi-Automated Control System for Reaching Movements in EMG Shoulder Disarticulation Prosthesis Based on Mixed Reality Device

Authors: Shunta Togo, Kazuaki Matsumoto, Susumu Kimizuka, Yinlai Jiang, Hiroshi Yokoi

Source: IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 55-64 (2021)

Subject Terms: Control system, EMG shoulder disarticulation prosthesis, man-machine interface, mixed reality, wearable robot, Computer applications to medicine. Medical informatics, R858-859.7, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://ieeexplore.ieee.org/document/9351668/; https://doaj.org/toc/2644-1276

Access URL: https://doaj.org/article/ae8545f481664ae2bda77b4f66607b4d

Different intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis

Authors: Naoki Ichinose, Gakushi Yoshikawa, Eri Fukao, Mai Ichisawa, Tomoaki Takahata, Yuki Enoki, Kazuaki Taguchi, Toshimi Oda, Kazuo Tsutsumi, Kazuaki Matsumoto

Source: International Journal of Infectious Diseases, Vol 110, Iss , Pp 382-384 (2021)

Subject Terms: Linezolid, Meningitis, Cerebrospinal fluid, Pharmacokinetic, Drainage, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971221006317; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/df979eebf77943bd96241f7e12862477