Suppression of TLR4/NF-κB signaling by kaurenoic acid in a mice model of monosodium urate crystals-induced acute gout

Authors: Jamil, Maryam ^{a, b}, Zafar, Sana ^{a, b}, Bibi, Tehmina ^{a, b}, Buttar, Parveen Akhtar ^{a, b}, Shal, Bushra ^d, Shah, Kifayatullah ^b, Din, Fakhar ud ^{b, c}, Seo, Eun Kyoung ^{e, ⁎⁎}, Khan, Salman ^{a, b, ⁎}

Source: In Archives of Biochemistry and Biophysics March 2025 765

Safety evaluation of the food additive steviol glycosides, predominantly Rebaudioside M, produced by fermentation using Yarrowia lipolytica VRM

Authors: EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Gisela Degen, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Wim Mennes, Sabina Passamonti, Peter Moldeus, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, José Manuel Barat Baviera, David Gott, Lieve Herman, Jean‐Charles Leblanc, Detlef Wölfle, Jaime Aguilera Entrena, Civitella Consuelo, Agnieszka Mech, Salvatore Multari, Vasantha Palaniappan, Laura Ruggeri, Camilla Smeraldi, Alexandra Tard, Laurence Castle

Source: EFSA Journal, Vol 21, Iss 12, Pp n/a-n/a (2023)

Subject Terms: enzymatic bioconversion, kaurenoic acid, rebaudioside M, Steviol glycoside preparations, Yarrowia lipolytica VRM, Nutrition. Foods and food supply, TX341-641, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://doaj.org/toc/1831-4732

Access URL: https://doaj.org/article/0bf1bcff448a4ec2b4fb504cef23fe16

In vitro metabolism of copalic and kaurenoic acids in rat and human liver microsomes

Authors: Mauro, Mariana, Silva, Rodrigo Moreira da, Campos, Michel Leandro de, Bauermeister, Anelize, Lopes, Norberto Peporine, Moraes, Natalia Valadares de

Source: Química Nova. June 2021 44(6)

Subject Terms: metabolism, liver microsomes, copalic acid, kaurenoic acid, Copaifera sp

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In vitro metabolism of copalic and kaurenoic acids in rat and human liver microsomes

Authors: Mariana Mauro, Rodrigo Moreira da Silva, Michel Leandro de Campos, Anelize Bauermeister, Norberto Peporine Lopes, Natalia Valadares de Moraes

Source: Química Nova, Vol 44, Iss 6, Pp 700-708 (2021)

Subject Terms: metabolism, liver microsomes, copalic acid, kaurenoic acid, Copaifera sp, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422021000600700&tlng=en; https://doaj.org/toc/1678-7064

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KAURENOIC ACID DETERMINATION IN EXTRACT, TINCTURE AND SYRUP OF Mikania glomerata BY HPLC-QQQ-MS/MS

Authors: Moreira, Alan F. Canevari, Alves, Victor Rodrigues, Micke, Gustavo A., Duarte, Lucas M., Lima, Nerilson M., Oliveira, Marcone A. L. de

Source: Química Nova. May 2020 43(5)

Subject Terms: medicinal plants, Mikania glomerata, kaurenoic acid, method development, HPLC-QqQ-MS/MS

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000500632

KAURENOIC ACID DETERMINATION IN EXTRACT, TINCTURE AND SYRUP OF Mikania glomerata BY HPLC-QQQ-MS/MS

Authors: Alan F. Canevari Moreira, Victor Rodrigues Alves, Gustavo A. Micke, Lucas M. Duarte, Nerilson M. Lima, Marcone A. L. de Oliveira

Source: Química Nova, Vol 43, Iss 5, Pp 632-635 (2020)

Subject Terms: medicinal plants, Mikania glomerata, kaurenoic acid, method development, HPLC-QqQ-MS/MS, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422020000500632&tlng=en; http://www.scielo.br/pdf/qn/v43n5/0100-4042-qn-43-05-0632.pdf; https://doaj.org/toc/1678-7064

Access URL: https://doaj.org/article/63561c15cd744f7094822f74e89ffaa9

Redesign and reconstruction of a steviol-biosynthetic pathway for enhanced production of steviol in Escherichia coli

Authors: Jun Ho Moon, Kunjoong Lee, Jun Ho Lee, Pyung Cheon Lee

Source: Microbial Cell Factories, Vol 19, Iss 1, Pp 1-12 (2020)

Subject Terms: Steviol, Kaurenoic acid, Kaurene, Metabolic engineering, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2859

Access URL: https://doaj.org/article/bce19294db46490bb8f5fe274b0209f6

Overexpression of SrDXS1 and SrKAH enhances steviol glycosides content in transgenic Stevia plants

Authors: Junshi Zheng, Yan Zhuang, Hui-Zhu Mao, In-Cheol Jang

Source: BMC Plant Biology, Vol 19, Iss 1, Pp 1-16 (2019)

Subject Terms: 1-deoxy-d-xylulose-5-phosphate synthase 1, Kaurenoic acid hydroxylase, Metabolic engineering, Stevia transformation, Steviol glycosides, Transgenic Stevia, Botany, QK1-989

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12870-018-1600-2; https://doaj.org/toc/1471-2229

Access URL: https://doaj.org/article/6fe0bf2e950b4b96a8750f9c24c39bb5

Effects of methyl jasmonate, on stevioside and rebaudioside A content and expression of the ent-Kaurenoic acid 13-hydroxylase gene in Stevia rebaudiana Bert. in vitro

Authors: Mehrdad Behmanesh, Mozaffar Sharifi, Kamran Moradi Peynevandi

Source: Zīst/shināsī-i Giyāhī-i Īrān, Vol 6, Iss 21, Pp 99-110 (2014)

Subject Terms: ent-Kaurenoic acid 13-Hydroxylase, Stevia rebuadiana, Stevioside, Rebaudioside A, ent, Kaurenoic acid 13, Hydroxylase, Methyl jasmonate, Plant culture, SB1-1110, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://ijpb.ui.ac.ir/article_18942_04a17170b035af58a2f0457bca7c39c7.pdf; https://doaj.org/toc/2008-8264; https://doaj.org/toc/2322-2204

Access URL: https://doaj.org/article/603739ea2b514118895811d26001f1d8

Synthesis, in vitro Antimalarial Activity and in silico Studies of Hybrid Kauranoid 1,2,3-Triazoles Derived from Naturally Occurring Diterpenes

Authors: Santos, Juliana de O., Pereira, Guilherme R., Brandão, Geraldo C., Borgati, Tatiane F., Arantes, Lucas M., Paula, Renata C. de, Soares, Luciana F., Nascimento, Maria F. A. do, Ferreira, Márlia R. C., Taranto, Alex G., Varotti, Fernando P., Oliveira, Alaíde B. de

Source: Journal of the Brazilian Chemical Society. March 2016 27(3)

Subject Terms: kaurenoic acid, xylopic acid, click chemistry, antiplasmodial activity, PfATP6 inhibitors

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532016000300551

New Non-Toxic Semi-Synthetic Derivatives from Natural Diterpenes Displaying Anti-Tuberculosis Activity

Authors: Priscilla M. Matos, Brian Mahoney, Yohan Chan, David P. Day, Mirela M. W. Cabral, Carlos H. G. Martins, Raquel A. Santos, Jairo K. Bastos, Philip C. Bulman Page, Vladimir C. G. Heleno

Source: Molecules, Vol 20, Iss 10, Pp 18264-18278 (2015)

Subject Terms: kaurenoic acid, copalic acid, structural modification, diterpene derivatives, anti-tuberculosis activity, cytotoxicity, Mycobacterium tuberculosis, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/20/10/18264; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/92d385264f71414cb72778ef37c003b1

Antinociceptive Effect of Hinokinin and Kaurenoic Acid Isolated from Aristolochia odoratissima L.

Authors: Rosa Mariana Montiel-Ruiz, Marcos Córdova-de la Cruz, Manasés González-Cortázar, Alejandro Zamilpa, Abraham Gómez-Rivera, Ricardo López-Rodríguez, Carlos Ernesto Lobato-García, Ever A. Blé-González

Source: Molecules, Vol 25, Iss 6, p 1454 (2020)

Subject Terms: aristolochia odoratissima l., antinociception, hinokinin, kaurenoic acid, formalin test, Organic chemistry, QD241-441

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Relation: https://www.mdpi.com/1420-3049/25/6/1454; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/293e77dbc8b14b0a956b78e91ce1f2aa

Kaurene diterpene induces apoptosis in U87 human malignant glioblastoma cells by suppression of anti-apoptotic signals and activation of cysteine proteases

Authors: Lizarte Neto, F.S., Tirapelli, D.P.C., Ambrosio, S.R., Tirapelli, C.R., Oliveira, F.M., Novais, P.C., Peria, F.M., Oliveira, H.F., Carlotti Junior, C.G., Tirapelli, L.F.

Source: Brazilian Journal of Medical and Biological Research. January 2013 46(1)

Subject Terms: Kaurenoic acid, Glioblastoma, miR-21, c-FLIP, Apoptosis

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000100071

Molecular evolution of the ent-kaurenoic acid oxidase gene in Oryzeae

Authors: Yang, Yanhua, Chen, Keping

Source: Genetics and Molecular Biology. January 2012 35(2)

Subject Terms: codon usage bias, ent-kaurenoic acid oxidase (KAO), positive selection, rate heterogeneity, substitution rate

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300011

[Untitled]

Authors: F.S. Lizarte Neto, D.P.C. Tirapelli, S.R. Ambrosio, C.R. Tirapelli, F.M. Oliveira, P.C. Novais, F.M. Peria, H.F. Oliveira, C.G. Carlotti Junior, L.F. Tirapelli

Source: Brazilian Journal of Medical and Biological Research, Vol 46, Iss 1, Pp 71-80 (2013)

Subject Terms: Kaurenoic acid, Glioblastoma, miR-21, c-FLIP, Apoptosis, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000100071; https://doaj.org/toc/0100-879X; https://doaj.org/toc/1414-431X

Access URL: https://doaj.org/article/def0d6e9c0dd4595aafdbfb57968b5b2

iso-Kaurenoic acid from Wedelia paludosa D.C.

Authors: Batista, Ronan, García, Pablo A., Castro, María Ángeles, Del Corral, José M. Miguel, Feliciano, Arturo S., Oliveira, Alaíde B. de

Source: Anais da Academia Brasileira de Ciências. December 2010 82(4)

Subject Terms: Asteraceae, iso-kaurenoic acid, silica gel impregnated with silver nitrate, Wedelia paludosa D.C

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652010000400004

Kaurene diterpene induces apoptosis in U87 human malignant glioblastoma cells by suppression of anti-apoptotic signals and activation of cysteine proteases

Authors: F.S. Lizarte Neto, D.P.C. Tirapelli, S.R. Ambrosio, C.R. Tirapelli, F.M. Oliveira, P.C. Novais, F.M. Peria, H.F. Oliveira, C.G. Carlotti Junior, L.F. Tirapelli

Source: Brazilian Journal of Medical and Biological Research, Vol 46, Iss 1, Pp 71-80 (2013)

Subject Terms: Kaurenoic acid, Glioblastoma, miR-21, c-FLIP, Apoptosis, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000100071&lng=en&tlng=en; https://doaj.org/toc/1414-431X

Access URL: https://doaj.org/article/7f3d4ac09b45401a9f415f1decb67bba

Evaluation of the molluscicidal and Schistosoma mansoni cercariae activity of Croton floribundus extracts and kaurenoic acid

Authors: Medina, Janaina M., Peixoto, Juliana L. B., Silva, Adriano A., Haraguchi, Shirani K., Falavigna, Dina L. M., Zamuner, Maria L. M., Sarragiotto, Maria H., Vidotti, Gentil J.

Source: Revista Brasileira de Farmacognosia. March 2009 19(1b)

Subject Terms: Biomphalaria glabrata, Croton floribundus, Artemia salina, kaurenoic acid, Schistosoma mansoni, cercariae

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Cytotoxicity of Wedelia paludosa D.C. extracts and constituents

Authors: Batista, Ronan, Brandão, Geraldo C., Braga, Fernão C., Oliveira, Alaíde B.

Source: Revista Brasileira de Farmacognosia. March 2009 19(1a)

Subject Terms: Wedelia paludosa, Asteraceae, cytotoxic activity, brine shrimp lethality bioassay, kaurenoic acid, grandiflorenic acid, HPLC

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2009000100009

Molecular evolution of the ent-kaurenoic acid oxidase gene in Oryzeae

Authors: Yanhua Yang, Keping Chen

Source: Genetics and Molecular Biology, Vol 35, Iss 2, Pp 448-454 (2012)

Subject Terms: codon usage bias, ent-kaurenoic acid oxidase (KAO), positive selection, rate heterogeneity, substitution rate, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300011; https://doaj.org/toc/1415-4757; https://doaj.org/toc/1678-4685

Access URL: https://doaj.org/article/c92ac6d54a7b4237bcfc73d796018c3e