Regulation of pathway choice in DNA repair after double-strand breaks

Authors: Kumari, Nitu ^{1, a}, Kaur, Ekjot ^{2, a}, Raghavan, Sathees C. ^{1, ⁎⁎}, Sengupta, Sagar ^{2, 3, ⁎}

Source: In Current Opinion in Pharmacology February 2025 80

Abrogation of FBW7α-dependent p53 degradation enhances p53’s function as a tumor suppressor

Alternate Title: ACCELERATED COMMUNICATION: FBW7α degrades p53 (English)

Authors: Tripathi, Vivek, Kaur, Ekjot, Kharat, Suhas Sampat, Hussain, Mansoor, Damodaran, Arun Prasath, Kulshrestha, Swati, Sengupta, Sagar

Source: In Journal of Biological Chemistry 6 September 2019 294(36):13224-13232

BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor

Authors: Priyadarshini, Raina, Hussain, Mansoor, Attri, Preeti, Kaur, Ekjot, Tripathi, Vivek, Priya, Swati, Dhapola, Parashar, Saha, Dhurjhoti, Madhavan, Vinoth, Chowdhury, Shantanu, Sengupta, Sagar

Source: In Cell Reports 24 July 2018 24(4):947-961

Novel analogs of sulfasalazine as system xc− antiporter inhibitors: Insights from the molecular modeling studies

Authors: Patel, Dhavalkumar, Kharkar, Prashant S., Gandhi, Neha S., Kaur, Ekjot, Dutt, Shilpee, Nandave, Mukesh

Source: Drug development research. 80(6):758-777

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090923405.0x000001&indx=1&recIds=ETOCvdc_100090923405.0x000001

Comparative transcriptome and tissue-specific expression analysis of genes reveal tissue-cultured plants as an alternative source for phenylethanoids and phenylpropanoids in Rhodiola imbricata (Edgew.)

Authors: Rattan, Shiv, Kumar, Pankaj, Kaur, Ekjot, Sood, Archit, Acharya, Vishal, Warghat, Ashish R.

Source: Gene. 836

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167451950.0x000001&indx=1&recIds=ETOCvdc_100167451950.0x000001

Inhibition of novel GCN5–ATM axis restricts the onset of acquired drug resistance in leukemia

Authors: Salunkhe, Sameer, Mishra, Saket V., Nair, Jyothi, Ghosh, Samadri, Choudhary, Neha, Kaur, Ekjot, Shah, Sanket, Patkar, Ketaki, Anand, Dev, Khattry, Navin, Hasan, Syed K., Dutt, Shilpee

Source: International journal of cancer. 142(10):2175-2185

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135786310.0x000001&indx=1&recIds=ETOCvdc_100135786310.0x000001

Molecular features unique to glioblastoma radiation resistant residual cells may affect patient outcome - a short report

Authors: Kaur, Ekjot, Goda, Jayant S., Ghorai, Atanu, Salunkhe, Sameer, Shetty, Prakash, Moiyadi, Aliasgar V., Sridhar, Epari, Mahajan, Abhishek, Jalali, Rakesh, Dutt, Shilpee

Source: Cellular oncology. 42(1):107-116

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130351500.0x000001&indx=1&recIds=ETOCvdc_100130351500.0x000001

Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models.

Authors: Kaur, Ekjot¹, Agrawal, Ritu¹, Arun, Rimpy¹, Madhavan, Vinoth¹, Srivastava, Vivek¹, Kumar, Dilip², Rath, Pragyan Parimita³, Kumar, Nitin¹, Vedagopuram, Sreekanth⁴, Pandey, Nishant⁴, Priya, Swati¹, Legembre, Patrick⁵, Gourinath, Samudrala³, Bajaj, Avinash⁴, Sengupta, Sagar^1,6 ssg2@nibmg.ac.in

Source: Journal of Clinical Investigation. 4/15/2024, Vol. 134 Issue 8, p1-15. 15p.

Subject Terms: *COLON cancer, *SMALL molecules, *DRUG resistance in cancer cells, *HOMOLOGOUS recombination, *COLON tumors, *CISPLATIN

Company/Entity: EUROPEAN Medicines Agency , UNITED States. Food & Drug Administration

The oscillation of mitotic kinase governs cell cycle latches in mammalian cells.

Authors: Dragoi, Calin-Mihai¹, Kaur, Ekjot², Barr, Alexis R.^2,3, Tyson, John J.⁴, Novák, Béla¹ bela.novak@bioch.ox.ac.uk

Source: Journal of Cell Science. Feb2024, Vol. 137 Issue 3, p1-15. 15p.

Subject Terms: *MAMMALIAN cell cycle, *CELL cycle proteins, *OSCILLATIONS, *CYCLINS

De novo transcriptome analysis provides insights into formation of in vitro adventitious root from leaf explants of Arnebia euchroma.

Authors: Devi, Jyoti^1,2 (AUTHOR), Kaur, Ekjot^1,2 (AUTHOR), Swarnkar, Mohit Kumar¹ (AUTHOR), Acharya, Vishal^1,2 (AUTHOR) vishal@ihbt.res.in, Bhushan, Shashi^1,2,3 (AUTHOR) sbhushan@ihbt.res.in

Source: BMC Plant Biology. 9/9/2021, Vol. 21 Issue 1, p1-16. 16p.

Subject Terms: *PLANT tissue culture, *TRANSCRIPTOMES, *ROOT formation, *ROOT development, *PLANT hormones

Systematic analyses with genomic and metabolomic insights reveal a new species, Ophiocordyceps indica sp. nov. from treeline area of Indian Western Himalayan region.

Authors: Sharma, Aakriti, Kaur, Ekjot, Joshi, Robin, Kumari, Pooja, Khatri, Abhishek, Swarnkar, Mohit Kumar, Kumar, Dinesh, Acharya, Vishal, Nadda, Gireesh

Source: Frontiers in Microbiology; 2023, p1-23, 23p

Subject Terms: GENOMICS, TIMBERLINE, CATERPILLARS, METABOLOMICS, SPECIES

Geographic Terms: HIMACHAL Pradesh (India)

Molecular features unique to glioblastoma radiation resistant residual cells may affect patient outcome - a short report.

Authors: Kaur, Ekjot^1,2, Goda, Jayant S.^2,3, Ghorai, Atanu^1,2, Salunkhe, Sameer^1,2, Shetty, Prakash^2,4, Moiyadi, Aliasgar V.^2,4, Sridhar, Epari^2,5, Mahajan, Abhishek^2,3, Jalali, Rakesh^2,3, Dutt, Shilpee^1,2 sdutt@actrec.gov.in

Source: Cellular Oncology (2211-3428). Feb2019, Vol. 42 Issue 1, p107-116. 10p.

Subject Terms: *GLIOBLASTOMA multiforme, *DNA repair, *RADIOTHERAPY, *IMMUNOFLUORESCENCE, *WESTERN immunoblotting

Genome-Wide Identification of GRAS Transcription Factors and Their Potential Roles in Growth and Development of Rose (Rosa chinensis).

Authors: Kumari, Priya, Gahlaut, Vijay, Kaur, Ekjot, Singh, Sanatsujat, Kumar, Sanjay, Jaiswal, Vandana

Source: Journal of Plant Growth Regulation; Mar2023, Vol. 42 Issue 3, p1505-1521, 17p

Subject Terms: TRANSCRIPTION factors, GENE families, ROSES, GENE expression, POTENTIAL functions, DROUGHT tolerance

MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria.

Authors: Hussain, Mansoor¹, Mohammed, Aftab¹, Saifi, Shabnam¹, Khan, Aamir¹, Kaur, Ekjot¹, Priya, Swati¹, Agarwal, Himanshi¹, Sengupta, Sagar¹, sagar@nii.ac.in

Source: PLoS Biology; 3/3/2021, Vol. 19 Issue 3, p1-28, 28p, 2 Diagrams, 5 Graphs

Glioblastoma recurrent cells switch between ATM and ATR pathway as an alternative strategy to survive radiation stress.

Authors: Kaur, Ekjot, Ketkar, Madhura, Dutt, Shilpee

Source: Medical Oncology; May2022, Vol. 39 Issue 5, p1-7, 7p

CDX2 inducible microRNAs sustain colon cancer by targeting multiple DNA damage response pathway factors.

Authors: Priya, Swati¹, Kaur, Ekjot¹, Kulshrestha, Swati¹, Pandit, Awadhesh¹, Gross, Isabelle², Kumar, Nitin¹, Agarwal, Himanshi¹, Khan, Aamir¹, Shyam, Radhey¹, Bhagat, Prakash³, Prabhu, Jyothi S.⁴, Nagarajan, Perumal¹, Deo, S. V. S.³, Bajaj, Avinash⁵, Freund, Jean-Noël², Mukhopadhyay, Arnab¹, Sengupta, Sagar¹

Source: Journal of Cell Science. Aug2021, Vol. 134 Issue 15, p1-19. 19p.

Subject Terms: *DNA damage, *COLON cancer, *BIOMARKERS, *MICRORNA, *BRCA genes, *CANCER cells

Functions of BLM Helicase in Cells: Is It Acting Like a Double-Edged Sword?

Authors: Kaur, Ekjot, Agrawal, Ritu, Sengupta, Sagar

Source: Frontiers in Genetics; 3/12/2021, Vol. 11, pN.PAG-N.PAG, 14p

Subject Terms: DNA helicases, GENETIC mutation, DNA replication, DNA damage, GENES, PREMATURE aging (Medicine)

Inhibition of SETMAR–H3K36me2–NHEJ repair axis in residual disease cells prevents glioblastoma recurrence.

Authors: Kaur, Ekjot, Nair, Jyothi, Ghorai, Atanu, Mishra, Saket V, Achareker, Anagha, Ketkar, Madhura, Sarkar, Debashmita, Salunkhe, Sameer, Rajendra, Jacinth, Gardi, Nilesh, Desai, Sanket, Iyer, Prajish, Thorat, Rahul, Dutt, Amit, Moiyadi, Aliasgar, Dutt, Shilpee

Source: Neuro-Oncology; Dec2020, Vol. 22 Issue 12, p1785-1796, 12p

Novel analogs of sulfasalazine as system xc⁻ antiporter inhibitors: Insights from the molecular modeling studies.

Authors: Patel, Dhavalkumar, Kharkar, Prashant S., Gandhi, Neha S., Kaur, Ekjot, Dutt, Shilpee, Nandave, Mukesh

Source: Drug Development Research; Sep2019, Vol. 80 Issue 6, p758-777, 20p

Subject Terms: MOLECULAR models, GLIOBLASTOMA multiforme, BLOOD-brain barrier, EPILEPSY, PROTEIN models, LIPOXINS

This result is not displayed to guests.
Login for full access.