Mistimed restricted feeding disrupts circadian rhythms of male mating behavior and female preovulatory LH surges in mice

Authors: Kukino, Ayaka, Walbeek, Thijs J., Sun, Lori J., Watt, Alexander T., Park, Jin Ho, Kauffman, Alexander S., Butler, Matthew P.

Source: In Hormones and Behavior September 2022 145

Developmental sex differences in the peri-pubertal pattern of hypothalamic reproductive gene expression, including Kiss1 and Tac2, may contribute to sex differences in puberty onset

Authors: Semaan, Sheila J., Kauffman, Alexander S.

Source: In Molecular and Cellular Endocrinology 1 July 2022 551

Kisspeptin impacts on circadian and ultradian rhythms of core body temperature: Evidence in kisspeptin receptor knockout and kisspeptin knockdown mice

Authors: Kavanagh, Georgia S., Tadi, Jason, Balkenhol, Sydney M., Kauffman, Alexander S., Maloney, Shane K., Smith, Jeremy T.

Source: In Molecular and Cellular Endocrinology 15 February 2022 542

Neural and endocrine mechanisms underlying stress-induced suppression of pulsatile LH secretion

Authors: McCosh, Richard B., Breen, Kellie M., Kauffman, Alexander S.

Source: In Molecular and Cellular Endocrinology 1 December 2019 498

Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype

Authors: Tolson, Kristen P., Marooki, Nuha, Wolfe, Andrew, Smith, Jeremy T., Kauffman, Alexander S.

Source: In Molecular and Cellular Endocrinology 1 December 2019 498

Conditional knockout of kisspeptin signaling in brown adipose tissue increases metabolic rate and body temperature and lowers body weight

Authors: Tolson, Kristen P., Marooki, Nuha, De Bond, Julie‐Ann P., Walenta, Evelyn, Stephens, Shannon B.Z., Liaw, Reanna B., Savur, Rishi, Wolfe, Andrew, Oh, Da Young, Smith, Jeremy T., Kauffman, Alexander S.

Source: FASEB journal. 34(1):107-121

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134552708.0x000001&indx=1&recIds=ETOCvdc_100134552708.0x000001

Selective depletion of kisspeptin neurons in the hypothalamic arcuate nucleus in early juvenile life reduces pubertal LH secretion and delays puberty onset in mice.

Authors: Coutinho, Eulalia A., Esparza, Lourdes A., Steffen, Paige H., Liaw, Reanna, Bolleddu, Shreyana, Kauffman, Alexander S.

Source: FASEB Journal; 10/15/2024, Vol. 38 Issue 19, p1-19, 19p

Androgen Inhibition of Reproductive Neuroendocrine Function in Females and Transgender Males.

Authors: Kauffman, Alexander S

Source: Endocrinology; Oct2024, Vol. 165 Issue 10, p1-14, 14p

Subject Terms: GONADOTROPIN releasing hormone, TRANS men, HORMONE therapy, POLYCYSTIC ovary syndrome, TRANSGENDER people

Targeted inhibition of kisspeptin neurons reverses hyperandrogenemia and abnormal hyperactive LH secretion in a preclinical mouse model of polycystic ovary syndrome.

Authors: Coutinho, Eulalia A, Esparza, Lourdes A, Rodriguez, Julian, Yang, Jason, Schafer, Danielle, Kauffman, Alexander S

Source: Human Reproduction; Sep2024, Vol. 39 Issue 9, p2089-2103, 15p

Subject Terms: KISSPEPTIN neurons, POLYCYSTIC ovary syndrome, KISSPEPTINS, AROMATASE inhibitors, LABORATORY mice

Conditional Deletion of KOR (Oprk1) in Kisspeptin Cells Does Not Alter LH Pulses, Puberty, or Fertility in Mice

Authors: Coutinho, Eulalia A, Esparza, Lourdes A, Hudson, Alexandra D, Rizo, Nathanael, Steffen, Paige, Kauffman, Alexander S

Source: Endocrinology. 163(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164805112.0x000001&indx=1&recIds=ETOCvdc_100164805112.0x000001

Metabolic actions of kisspeptin signaling: Effects on body weight, energy expenditure, and feeding

Authors: Hudson, Alexandra D., Kauffman, Alexander S.

Source: Pharmacology and therapeutics. 231

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155250464.0x000001&indx=1&recIds=ETOCvdc_100155250464.0x000001

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice

Authors: Xie, Changchuan, Jonak, Carrie R., Kauffman, Alexander S., Coss, Djurdjica ^*

Source: In Molecular and Cellular Endocrinology 15 August 2015 411:223-231

Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge

Authors: Mohr, Margaret A, Esparza, Lourdes A, Steffen, Paige, Micevych, Paul E, Kauffman, Alexander S

Source: Endocrinology. 162(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130867700.0x000001&indx=1&recIds=ETOCvdc_100130867700.0x000001

Estrogen Regulation of the Molecular Phenotype and Active Translatome of AVPV Kisspeptin Neurons

Authors: Stephens, Shannon B Z, Kauffman, Alexander S

Source: Endocrinology. 162(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130288008.0x000001&indx=1&recIds=ETOCvdc_100130288008.0x000001

Daily successive changes in reproductive gene expression and neuronal activation in the brains of pubertal female mice

Authors: Semaan, Sheila J., Kauffman, Alexander S. ^*

Source: In Molecular and Cellular Endocrinology 5 February 2015 401:84-97

Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons

Authors: Koemeter-Cox, Andrew I., Sherwood, Thomas W., Green, Jill A., Steiner, Robert A., Berbari, Nicolas F., Yoder, Bradley K., Kauffman, Alexander S., Monsma, Paula C., Brown, Anthony, Askwith, Candice C., Mykytyn, Kirk

Source: Proceedings of the National Academy of Sciences of the United States of America, 2014 Jul . 111(28), 10335-10340.

Access URL: https://www.jstor.org/stable/23805751

Editorial: Hormone release patterns in mammals

Authors: Kauffman, Alexander S., Hoffmann, Hanne M.

Source: Molecular and cellular endocrinology. 507

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122034409.0x000001&indx=1&recIds=ETOCvdc_100122034409.0x000001

GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

Authors: Nicholas, Dequina A., Knight, Vashti S., Tonsfeldt, Karen J., Terasaka, Tomohiro, Molinar-Inglis, Olivia, Stephens, Shannon B. Z., Trejo, JoAnn, Kauffman, Alexander S., Mellon, Pamela L., Lawson, Mark A.

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174692750.0x000001&indx=1&recIds=ETOCvdc_100174692750.0x000001

Organizational and activational effects of sex steroids on kisspeptin neuron development

Authors: Poling, Matthew C., Kauffman, Alexander S.

Source: In Frontiers in Neuroendocrinology January 2013 34(1):3-17

Sexual differentiation and development of forebrain reproductive circuits

Authors: Semaan, Sheila J, Kauffman, Alexander S

Source: In Current Opinion in Neurobiology 2010 20(4):424-431