Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice

Authors: George Ssebyatika, Katja Dinkelborg, Luisa J. Ströh, Florian Hinte, Laura Corneillie, Lucas Hueffner, Elina M. Guzman, Prossie L. Nankya, Nina Plückebaum, Lukas Fehlau, Jonathan Garn, Nele Meyer, Sarah Prallet, Ann-Kathrin Mehnert, Anke R. M. Kraft, Lieven Verhoye, Carina Jacobsen, Eike Steinmann, Heiner Wedemeyer, Abel Viejo-Borbolla, Viet Loan Dao Thi, Thomas Pietschmann, Marc Lütgehetmann, Philip Meuleman, Maura Dandri, Thomas Krey, Patrick Behrendt

Source: Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/70fc6f1c219946bf8d2d9052b8b8987c

Monitoring of hepatitis E virus infection and replication by functional tagging of the ORF2 protein

Authors: Maliki Ankavay, Nathalie Da Silva, Angela Pollán, Noémie Oechslin, Katja Dinkelborg, Patrick Behrendt, Darius Moradpour, Jérôme Gouttenoire

Source: JHEP Reports, Vol 7, Iss 3, Pp 101293- (2025)

Subject Terms: HEV, HiBiT, ORF2 protein, random insertion, split-luciferase, transposon, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924002970; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/f99ca0b6aeba4df1ba220481dc47a93a

Dynamic evolution of the sofosbuvir-associated variant A1343V in HEV-infected patients under concomitant sofosbuvir-ribavirin treatment

Authors: André Gömer, Katja Dinkelborg, Mara Klöhn, Michelle Jagst, Michael Hermann Wißing, Nicola Frericks, Pia Nörenberg, Patrick Behrendt, Markus Cornberg, Heiner Wedemeyer, Eike Steinmann, Benjamin Maasoumy, Daniel Todt

Source: JHEP Reports, Vol 6, Iss 3, Pp 100989- (2024)

Subject Terms: Viral RNA-directed RNA polymerase inhibitors, high-throughput sequencing, resistance profiling, intra-host evolution, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923003208; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/ca23583ef8d0487da1ab21c7ddd9e36c