CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications

Authors: Daniel Allen, Orli Knop, Bryan Itkowitz, Nechama Kalter, Michael Rosenberg, Ortal Iancu, Katia Beider, Yu Nee Lee, Arnon Nagler, Raz Somech, Ayal Hendel

Source: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c083e55eea434c40b1934e6fc7cf4b59

Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs

Authors: Ortal Iancu, Daniel Allen, Orli Knop, Yonathan Zehavi, Dor Breier, Adaya Arbiv, Atar Lev, Yu Nee Lee, Katia Beider, Arnon Nagler, Raz Somech, Ayal Hendel

Source: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 105-121 (2023)

Subject Terms: MT: RNA/DNA Editing, CRISPR-Cas9, rAAV6, HSPCs, genome editing, gene regulation, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253122003237; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/ae155571bbed4c078012ef702c2c303a

CXCL13 chemokine is a novel player in multiple myeloma osteolytic microenvironment, M2 macrophage polarization, and tumor progression

Authors: Katia Beider, Valeria Voevoda-Dimenshtein, Ali Zoabi, Evgenia Rosenberg, Hila Magen, Olga Ostrovsky, Avichai Shimoni, Lola Weiss, Michal Abraham, Amnon Peled, Arnon Nagler

Source: Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-19 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/28b1779f57e848828346e9c476554774

P854: EFFECT OF HPSE AND HPSE2 SNPS ON THE RISK OF DEVELOPING PRIMARY PARASKELETAL MULTIPLE MYELOMA

Authors: Olga Ostrovsky, Katia Beider, Hila Magen, Merav Leiba, Israel Vlodavsky, Arnon Nagler

Source: HemaSphere, Vol 7, p e25846d4 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000970320.25846.d4; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/60148b467aa742649abe6de85f64194a

Genetically determined telomere length and multiple myeloma risk and outcome

Authors: Matteo Giaccherini, Angelica Macauda, Enrico Orciuolo, Marcin Rymko, Karolina Gruenpeter, Charles Dumontet, Malgorzata Raźny, Victor Moreno, Gabriele Buda, Katia Beider, Judit Varkonyi, Hervé Avet-Loiseau, Joaquín Martinez-Lopez, Herlander Marques, Marzena Watek, Maria Eugenia Sarasquete, Vibeke Andersen, Lionel Karlin, Anna Suska, Marcin Kruszewski, Niels Abildgaard, Marek Dudziński, Aleksandra Butrym, Arnold Nagler, Annette Juul Vangsted, Katalin Kadar, Tomczak Waldemar, Krzysztof Jamroziak, Svend Erik Hove Jacobsen, Lene Hyldahl Ebbesen, Michał Taszner, Grzegorz Mazur, Fabienne Lesueur, Matteo Pelosini, Ramon Garcia-Sanz, Artur Jurczyszyn, Delphine Demangel, Rui Manuel Reis, Elżbieta Iskierka-Jażdżewska, Miroslaw Markiewicz, Federica Gemignani, Edyta Subocz, Daria Zawirska, Agnieszka Druzd-Sitek, Anna Stępień, M. Henar Alonso, Juan Sainz, Federico Canzian, Daniele Campa

Source: Blood Cancer Journal, Vol 11, Iss 4, Pp 1-10 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/a30e9bbd7c0543db9834e87fd2531155

Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma

Authors: Olga Ostrovsky, Katia Beider, Hila Magen, Merav Leiba, Ralph D. Sanderson, Israel Vlodavsky, Arnon Nagler

Source: Cells, Vol 12, Iss 6, p 913 (2023)

Subject Terms: HPSE gene, HPSE2 gene, SNPs, multiple myeloma, extramedullary disease, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/6/913; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/96093207e230487dbe545e4390f6fa9f

Molecular and Functional Signatures Associated with CAR T Cell Exhaustion and Impaired Clinical Response in Patients with B Cell Malignancies

Authors: Katia Beider, Orit Itzhaki, Jacob Schachter, Ania Hava Grushchenko-Polaq, Valeria Voevoda-Dimenshtein, Evgenia Rosenberg, Olga Ostrovsky, Olivia Devillers, Ronnie Shapira Frommer, Li-at Zeltzer, Amos Toren, Elad Jacoby, Avichai Shimoni, Abraham Avigdor, Arnon Nagler, Michal J. Besser

Source: Cells, Vol 11, Iss 7, p 1140 (2022)

Subject Terms: CAR T, B cell malignancies, exhaustion, resistance, molecular signature, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/7/1140; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/02514ef3cdbe4b41b2bc1bbc9123ee34

Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation

Authors: Shahar Biechonski, Leonid Olender, Adi Zipin-Roitman, Muhammad Yassin, Nasma Aqaqe, Victoria Marcu-Malina, Melanie Rall-Scharpf, Magan Trottier, M. Stephen Meyn, Lisa Wiesmüller, Katia Beider, Yael Raz, Dan Grisaru, Arnon Nagler, Michael Milyavsky

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9313fac1c8ce4adb8917c5a6468462c9

CMV Seropositive Status Increases Heparanase SNPs Regulatory Activity, Risk of Acute GVHD and Yield of CD34+ Cell Mobilization

Authors: Olga Ostrovsky, Katia Beider, Yan Morgulis, Nira Bloom, Angel Cid-Arregui, Avichai Shimoni, Israel Vlodavsky, Arnon Nagler

Source: Cells, Vol 10, Iss 12, p 3489 (2021)

Subject Terms: HPSE gene, CMV, SNPs, enhancer, insulator, allogeneic HSCT, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/12/3489; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/a14e451496104742984e45ee76b62551

The HPSE Gene Insulator—A Novel Regulatory Element That Affects Heparanase Expression, Stem Cell Mobilization, and the Risk of Acute Graft versus Host Disease

Authors: Olga Ostrovsky, Polina Baryakh, Yan Morgulis, Margarita Mayorov, Nira Bloom, Katia Beider, Avichai Shimoni, Israel Vlodavsky, Arnon Nagler

Source: Cells, Vol 10, Iss 10, p 2523 (2021)

Subject Terms: HPSE gene, enhancer, insulator, SNPs, allogeneic HSCT, acute GVHD, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/10/2523; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/62328108394d4e648beef44b2a0652d4

Shaping of CD56bri Natural Killer Cells in Patients With Steroid-Refractory/Resistant Acute Graft-vs.-Host Disease via Extracorporeal Photopheresis

Authors: Ming Ni, Lei Wang, Mingya Yang, Brigitte Neuber, Leopold Sellner, Angela Hückelhoven-Krauss, Maria-Luisa Schubert, Thomas Luft, Ute Hegenbart, Stefan Schönland, Patrick Wuchter, Bao-an Chen, Volker Eckstein, William Krüger, Ronit Yerushalmi, Katia Beider, Arnon Nagler, Carsten Müller-Tidow, Peter Dreger, Michael Schmitt, Anita Schmitt

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: GvHD, ECP, immunomodulation, natural killer cells, anti-viral effect, anti-leukemia effect, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00547/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3d6c75863e2c4034873565fb0cd070dc

Characterization of cyclin E expression in multiple myeloma and its functional role in seliciclib-induced apoptotic cell death.

Authors: Liat Josefsberg Ben-Yehoshua, Katia Beider, Avichai Shimoni, Olga Ostrovsky, Michal Samookh, Amnon Peled, Arnon Nagler

Source: PLoS ONE, Vol 7, Iss 4, p e33856 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3338814?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0c806b6c216e4c80a8e056c4672e5273

Novel Strategies for Immunotherapy in Multiple Myeloma: Previous Experience and Future Directions

Authors: Ivetta Danylesko, Katia Beider, Avichai Shimoni, Arnon Nagler

Source: Clinical and Developmental Immunology, Vol 2012 (2012)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1740-2522; https://doaj.org/toc/1740-2530

Access URL: https://doaj.org/article/a04eafc67c174775b5da4b4516f1376a

Involvement of CCR6/CCL20/IL-17 axis in NSCLC disease progression.

Authors: Sophie Kirshberg, Uzi Izhar, Gail Amir, Jonathan Demma, Fiona Vernea, Katia Beider, Zippora Shlomai, Hanna Wald, Gideon Zamir, Oz M Shapira, Amnon Peled, Ori Wald

Source: PLoS ONE, Vol 6, Iss 9, p e24856 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3174223?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/92051df2fab7467db6dcba7266ebef30

Interaction between CXCR4 and CCL20 pathways regulates tumor growth.

Authors: Katia Beider, Michal Abraham, Michal Begin, Hanna Wald, Ido D Weiss, Ori Wald, Eli Pikarsky, Rinat Abramovitch, Evelyne Zeira, Eithan Galun, Arnon Nagler, Amnon Peled

Source: PLoS ONE, Vol 4, Iss 4, p e5125 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2659745?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0ccab68378004efcbddf7cba8d115914

IFN-γ Treatment at Early Stages of Influenza Virus Infection Protects Mice from Death in a NK Cell-Dependent Manner.

Authors: Ido D. Weiss, Ori Wald, Hanna Wald, Katia Beider, Michal Abraham, Eithan Galun, Arnon Nagler, Amnon Peled

Source: Journal of Interferon & Cytokine Research; Jun2010, Vol. 30 Issue 6, p439-449, 11p

Subject Terms: INFLUENZA vaccines, INTERFERONS, LABORATORY mice, INFLUENZA viruses, KILLER cells, PANDEMICS, INFLAMMATION, CYTOKINES