Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity

Authors: Helen Imrie, Hema Viswambharan, Natalie J Haywood, Katherine I Bridge, Nadira Y Yuldasheva, Stacey Galloway, Katie J Simmons, Richard M Cubbon, Piruthivi Sukumar, Nicole T Watt, Laeticia Lichtenstein, Judy I Wyatt, Hiromi Kudo, Robert Goldin, Baptiste Rode, Stephen B Wheatcroft, Mark T Kearney

Source: Adipocyte, Vol 11, Iss 1, Pp 366-378 (2022)

Subject Terms: Adipocyte, insulin‐like growth factor (IGF), lipodystrophy, obesity, browning, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Cytology, QH573-671, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3945; https://doaj.org/toc/2162-397X

Access URL: https://doaj.org/article/3a306229dac84d0493dc86af288e28b8

Common FXIII and fibrinogen polymorphisms in abdominal aortic aneurysms.

Authors: Fraser L Macrae, Hannah Lee Evans, Katherine I Bridge, Anne Johnson, D Julian A Scott, Robert A S Ariëns

Source: PLoS ONE, Vol 9, Iss 11, p e112407 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4226572?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6f32b8ae57d04f7bba552899bda48185

Studying Adipose Endothelial Cell/Adipocyte Cross-Talk in Human Subcutaneous Adipose Tissue

Authors: Oliver I. Brown, author¹, Katherine I. Bridge, author¹, Sam Straw, author¹, Natallia Makava, author¹, Jason Scragg, author¹, Sunti Limumpornpetch, author¹, Cheukyau Luk, author¹, Jessica Smith, author¹, Anna Skromna, author¹, Alexander F. Bruns, author¹, Piruthivi Sukumar, author¹, Lee D. Roberts, author¹, Richard Cubbon, author¹, Klaus K. Witte, author¹, Stephen Wheatcroft, author¹, Mark T. Kearney, author¹

Source: Journal of Visualized Experiments. (206)

Availability: http://www.jove.com/video/66608

Preservation of Smooth Muscle Cell Integrity and Function: A Target for Limiting Abdominal Aortic Aneurysm Expansion?

Authors: Emily R. Clark, Rebecca J. Helliwell, Marc A. Bailey, Karen E. Hemmings, Katherine I. Bridge, Kathryn J. Griffin, D. Julian A. Scott, Louise M. Jennings, Kirsten Riches-Suman, Karen E. Porter

Source: Cells, Vol 11, Iss 6, p 1043 (2022)

Subject Terms: abdominal aortic aneurysm, bioreactor, tissue strength, smooth muscle cell phenotype, proliferation, senescence, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/6/1043; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/bf66a1d854d54314911c41df8274de19

Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice

Authors: Cheukyau Luk, Katherine I. Bridge, Nele Warmke, Katie J. Simmons, Michael Drozd, Amy Moran, Amanda D. V. MacCannell, Chew W. Cheng, Sam Straw, Jason L. Scragg, Jessica Smith, Claire H. Ozber, Chloe G. Wilkinson, Anna Skromna, Natallia Makava, Hiran A. Prag, T. Simon Futers, Oliver I. Brown, Alexander-Francisco Bruns, Andrew MN Walker, Nicole T. Watt, Romana Mughal, Kathryn J. Griffin, Nadira Y. Yuldasheva, Sunti Limumpornpetch, Hema Viswambharan, Piruthivi Sukumar, David J. Beech, Antonio Vidal-Puig, Klaus K. Witte, Michael P. Murphy, Richard C. Hartley, Stephen B. Wheatcroft, Richard M. Cubbon, Lee D. Roberts, Mark T. Kearney, Natalie J. Haywood

Source: Nature Communications, Vol 16, Iss 1, Pp 1-15 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d77e74ff3433493a95b24c364e6056f9

Paracrine Role of the Endothelium in Metabolic Homeostasis in Health and Nutrient Excess

Authors: Cheukyau Luk, Natalie J. Haywood, Katherine I. Bridge, Mark T. Kearney

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: endothelium, adipose tissue, paracrine signaling, cardiometabolic syndrome, obesity, metabolism, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.882923/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/d4442bbb6490479aa8c9229753bbdac0