Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

Authors: Andrew L Hong, Yuen-Yi Tseng, Jeremiah A Wala, Won-Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles WM Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William C Hahn

Source: eLife, Vol 8 (2019)

Subject Terms: renal medullary carcinoma, SMARCB1, MLN2238, ubiquitin-proteasome system, cell cycle, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/44161; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/ea9c3a1d96864bb8bbdbc626e575f019

Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer

Authors: Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Y. Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie B. Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Monica Manam, Laura E. MacConaill, Evelina Ceca, Sidney N. Benich, Wendy B. London, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway

Source: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4017a15f72474d229f7c23ceb2ec8422

Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST].

Authors: Lorna Kelly, Kenneth Bryan, Su Young Kim, Katherine A Janeway, J Keith Killian, Hans-Ulrich Schildhaus, Markku Miettinen, Lee Helman, Paul S Meltzer, Matt van de Rijn, Maria Debiec-Rychter, Maureen O'Sullivan, NIH Pediatric and Wild-Type GIST Clinic

Source: PLoS ONE, Vol 8, Iss 5, p e64102 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3663836?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e2c502f366b0451e803fd03db8d24b5d

Author Correction: Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer

Authors: Suzanne J. Forrest, Hersh Gupta, Abigail Ward, Yvonne Y. Li, Duong Doan, Alyaa Al-Ibraheemi, Sanda Alexandrescu, Pratiti Bandopadhayay, Suzanne Shusterman, Elizabeth A. Mullen, Natalie B. Collins, Susan N. Chi, Karen D. Wright, Priti Kumari, Tali Mazor, Keith L. Ligon, Priyanka Shivdasani, Monica Manam, Laura E. MacConaill, Evelina Ceca, Sidney N. Benich, Wendy B. London, Richard L. Schilsky, Suanna S. Bruinooge, Jaime M. Guidry Auvil, Ethan Cerami, Barrett J. Rollins, Matthew L. Meyerson, Neal I. Lindeman, Bruce E. Johnson, Andrew D. Cherniack, Alanna J. Church, Katherine A. Janeway

Source: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/fb4f1740ba5f49008685d912d84b0bbb

An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma

Authors: David S. Shulman, Sarah B. Whittle, Didier Surdez, Kelly M. Bailey, Enrique de Álava, Jason T. Yustein, Adam Shlien, Masanori Hayashi, Alexander J. R. Bishop, Brian D. Crompton, Steven G. DuBois, Neerav Shukla, Patrick J. Leavey, Stephen L. Lessnick, Heinrich Kovar, Olivier Delattre, Thomas G. P. Grünewald, Cristina R. Antonescu, Ryan D. Roberts, Jeffrey A. Toretsky, Franck Tirode, Richard Gorlick, Katherine A. Janeway, Damon Reed, Elizabeth R. Lawlor, Patrick J. Grohar

Source: npj Precision Oncology, Vol 6, Iss 1, Pp 1-11 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/85d5d49a92054aefa68b0e44c262da64

Retrospective evaluation of single patient investigational new drug (IND) requests in pediatric oncology

Authors: David S. Shulman, Lulla V. Kiwinda, Stacey Edwards, Catherine M. Clinton, Sarah Hunt, Lianne Greenspan, Kristen D. Lawler, Gregory Reaman, Hasan Al‐Sayegh, Kira Bona, Allison F. O'Neill, Suzanne Shusterman, Katherine A. Janeway, Andrew E. Place, Susan N. Chi, Clement Ma, Steven G. DuBois

Source: Cancer Medicine, Vol 10, Iss 7, Pp 2310-2318 (2021)

Subject Terms: FDA, IND, investigational new drug, pediatric oncology, single patient IND, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/a55985f140e94952817cff413dfa8e6f

Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children’s Oncology Group

Authors: Lisa M. Kopp, Richard B. Womer, Cindy L. Schwartz, David H. Ebb, Vivian I. Franco, David Hall, Donald A. Barkauskas, Mark D. Krailo, Holcombe E. Grier, Paul A. Meyers, Leonard H. Wexler, Neyssa M. Marina, Katherine A. Janeway, Richard Gorlick, Mark L. Bernstein, Steven E. Lipshultz, for the Children’s Oncology Group

Source: Cardio-Oncology, Vol 5, Iss 1, Pp 1-12 (2019)

Subject Terms: Osteosarcoma, Pediatrics, Cardiotoxicity, Doxorubicin, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40959-019-0050-9; https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/c1df26e926ca40859f1f7499883d65cd

Integrated genetic and pharmacologic interrogation of rare cancers

Authors: Andrew L. Hong, Yuen-Yi Tseng, Glenn S. Cowley, Oliver Jonas, Jaime H. Cheah, Bryan D. Kynnap, Mihir B. Doshi, Coyin Oh, Stephanie C. Meyer, Alanna J. Church, Shubhroz Gill, Craig M. Bielski, Paula Keskula, Alma Imamovic, Sara Howell, Gregory V. Kryukov, Paul A. Clemons, Aviad Tsherniak, Francisca Vazquez, Brian D. Crompton, Alykhan F. Shamji, Carlos Rodriguez-Galindo, Katherine A. Janeway, Charles W. M. Roberts, Kimberly Stegmaier, Paul van Hummelen, Michael J. Cima, Robert S. Langer, Levi A. Garraway, Stuart L. Schreiber, David E. Root, William C. Hahn, Jesse S. Boehm

Source: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a374f09a5d1640b381b40c1ebaec01db

Emerging concepts for PI3K/mTOR inhibition as a potential treatment for osteosarcoma [version 1; referees: 2 approved]

Authors: Michael W. Bishop, Katherine A. Janeway

Source: F1000Research, Vol 5 (2016)

Subject Terms: Cancer Therapeutics, Cell Growth & Division, Cell Signaling, Medical Genetics, Pediatric Oncology, Sarcomas, Medicine, Science

File Description: electronic resource

Relation: http://f1000research.com/articles/5-1590/v1; https://doaj.org/toc/2046-1402

Access URL: https://doaj.org/article/ed29982a5afa49f89328b879bba1d319

A single‐institution pediatric and young adult interventional oncology collaborative: Novel therapeutic options for relapsed/refractory solid tumors

Authors: Raja Shaikh, Brent R. Weil, Christopher B. Weldon, Nan Chen, Wendy B. London, Morgan Krush, Megan Anderson, Mark Gebhardt, Alanna J. Church, Steven G. DuBois, Yana Pikman, Jennifer Spidle, Catherine B. Wall, Angela Feraco, Nicole J. Ullrich, Jennifer W. Mack, Elizabeth Mullen, Junne Kamihara, Suzanne Forrest, Suzanne Shusterman, Katherine A. Janeway, Ahmad Alomari, Horacio Padua, Carlos Rodriguez‐Galindo, Allison F. O'Neill

Source: Cancer Medicine, Vol 12, Iss 12, Pp 13300-13308 (2023)

Subject Terms: interventional, mRECIST, pediatric, radiology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/c80b0344ed624477a0354a19d3dcdca0