Leukocyte profiles across the cardiovascular disease continuum: A population-based cohort study

Authors: Groot, Hilde E., van Blokland, Irene V., Lipsic, Erik, Karper, Jacco C., van der Harst, Pim

Source: In Journal of Molecular and Cellular Cardiology January 2020 138:158-164

Translational overview of cytokine inhibition in acute myocardial infarction and chronic heart failure

Authors: Hartman, Minke H.T., Groot, Hilde E., Leach, Irene Mateo, Karper, Jacco C., van der Harst, Pim

Source: In Trends in Cardiovascular Medicine August 2018 28(6):369-379

High-sensitivity C-reactive protein and long term reperfusion success of primary percutaneous intervention in ST-elevation myocardial infarction

Authors: Groot, Hilde E., Karper, Jacco C., Lipsic, Erik, van Veldhuisen, Dirk J., van der Horst, Iwan C.C., van der Harst, Pim

Source: In International Journal of Cardiology 1 December 2017 248:51-56

RP105 deficiency attenuates early atherosclerosis via decreased monocyte influx in a CCR2 dependent manner

Authors: Wezel, Anouk, van der Velden, Daniël, Maassen, Johanna M., Lagraauw, H. Maxime, de Vries, Margreet R., Karper, Jacco C., Kuiper, Johan, Bot, Ilze, Quax, Paul H.A.

Source: In Atherosclerosis January 2015 238(1):132-139

A randomized controlled trial of eplerenone in asymptomatic phospholamban p.Arg14del carriers.

Authors: Brouwer, Remco de, Rijdt, Wouter P te, Hoorntje, Edgar T, Amin, Ahmad, Asselbergs, Folkert W, Cox, Moniek G P J, Heijden, Jeroen F van der, Hillege, Hans, Karper, Jacco C, Mahmoud, Belend, van der Meer, Peter, Oomen, Anton, Riele, Anneline S J M te, Silljé, Herman H W, Tan, Hanno L, Tintelen, Jan Peter van, Veldhuisen, Dirk J van, Westenbrink, Berend Daan, Wiesfeld, Ans C P, Willems, Tineke P

Source: European Heart Journal; 10/21/2023, Vol. 44 Issue 40, p4284-4287, 4p

Subject Terms: PHOSPHOLAMBAN, ARRHYTHMIA, RANDOMIZED controlled trials, ARRHYTHMOGENIC right ventricular dysplasia, VENTRICULAR arrhythmia, HEART failure, CARDIAC magnetic resonance imaging

TLR4 Accessory Molecule RP105 (CD180) Regulates Monocyte-Driven Arteriogenesis in a Murine Hind Limb Ischemia Model.

Authors: Bastiaansen, Antonius J. N. M.^1,2, Karper, Jacco C.^1,2, Wezel, Anouk^1,2,3, de Boer, Hetty C.^2,4, Welten, Sabine M. J.^1,2, de Jong, Rob C. M.^1,2, Peters, Erna A. B.^1,2, de Vries, Margreet R.^1,2, van Oeveren-Rietdijk, Annemarie M.^2,4, van Zonneveld, Anton Jan^2,4, Hamming, Jaap F.¹, Nossent, A. Yaël^1,2 a.y.nossent@lumc.nl, Quax, Paul H. A.^1,2 p.h.a.quax@lumc.nl

Source: PLoS ONE. Jun2014, Vol. 9 Issue 6, p1-12. 12p.

Subject Terms: *TOLL-like receptors, *MONOCYTES, *IMMUNOHISTOCHEMISTRY, *DEVELOPMENTAL biology, *NATURAL immunity, *MACROPHAGES

TLR Accessory Molecule RP105 (CD180) Is Involved in Post-Interventional Vascular Remodeling and Soluble RP105 Modulates Neointima Formation.

Authors: Karper, Jacco C.^1,2, Ewing, Mark M.^1,2,3, de Vries, Margreet R.^1,2,3, de Jager, Saskia C. A.⁴, Peters, Erna A. B.^1,2, de Boer, Hetty C.^2,5, van Zonneveld, Anton-Jan^2,5, Kuiper, Johan⁴, Huizinga, Eric G.⁶, Brondijk, T. Harma C.⁶, Jukema, J. Wouter³, Quax, Paul H. A.^1,2 p.h.a.quax@lumc.nl

Source: PLoS ONE. Jul2013, Vol. 8 Issue 7, p1-9. 9p.

Subject Terms: *CELLULAR signal transduction, *VASCULAR smooth muscle, *MUSCLE cells, *FEMORAL artery, *GENETIC transformation, *CORONARY disease, *IMMUNOTHERAPY

BNP in heart failure: even leucocytes cannot escape its influence.

Authors: Karper, Jacco C.¹, Westenbrink, B. Daan¹

Source: European Journal of Heart Failure. Jun2015, Vol. 17 Issue 6, p536-538. 3p. 1 Diagram.

Subject Terms: *HEART failure patients, *HEART failure, *BRAIN natriuretic factor, *BIOMARKERS, *LEUKOCYTES, *DIAGNOSIS

Genetically Determined ABO Blood Group and its Associations With Health and Disease.

Authors: Groot, Hilde E., Villegas Sierra, Laura E., Said, M. Abdullah, Lipsic, Erik, Karper, Jacco C., van der Harst, Pim

Source: Arteriosclerosis, Thrombosis & Vascular Biology; Mar2020, Vol. 40 Issue 3, p830-838, 9p

Plasma interleukin 6 levels are associated with cardiac function after ST-elevation myocardial infarction.

Authors: Groot, Hilde E., Al Ali, Lawien, van der Horst, Iwan C. C., Schurer, Remco A. J., van der Werf, Hindrik W., Lipsic, Erik, van Veldhuisen, Dirk J., Karper, Jacco C., van der Harst, Pim

Source: Clinical Research in Cardiology; Jun2019, Vol. 108 Issue 6, p612-621, 10p

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Human genetic determinants of the gut microbiome and their associations with health and disease: a phenome-wide association study.

Authors: Groot, Hilde E., van de Vegte, Yordi J., Verweij, Niek, Lipsic, Erik, Karper, Jacco C., van der Harst, Pim

Source: Scientific Reports; 9/8/2020, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p

Subject Terms: HUMAN genetics, GUT microbiome, MEDICAL genetics, PREBIOTICS, PROBIOTICS

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