Primary Nucleation of Polymorphic α-Synuclein Dimers Depends on Copper Concentrations and Definite Copper-Binding Site

Authors: Carmia Blacher, Karina Abramov-Harpaz, Yifat Miller

Source: Biomolecules, Vol 14, Iss 6, p 627 (2024)

Subject Terms: Parkinson’s disease, metal ions, α-synuclein, amyloids, self-assembly, neurodegenerative diseases, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/6/627; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/5011fecde52e4af4910bb027b5b67a7a

Insights into Non-Proteolytic Inhibitory Mechanisms of Polymorphic Early-Stage Amyloid β Oligomers by Insulin Degrading Enzyme

Authors: Karina Abramov-Harpaz, Yifat Miller

Source: Biomolecules, Vol 12, Iss 12, p 1886 (2022)

Subject Terms: molecular dynamics simulations, amyloids, Alzheimer, insulin-degrading enzyme, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/12/1886; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/f2b0a42846b34f8cbd24434c1c5ed7e3

PLA2-Triggered Activation of Cyclosporine-Phospholipid Prodrug as a Drug Targeting Approach in Inflammatory Bowel Disease Therapy

Authors: Milica Markovic, Shimon Ben-Shabat, Jagadeesh Nagendra Manda, Karina Abramov-Harpaz, Clil Regev, Yifat Miller, Aaron Aponick, Ellen M. Zimmermann, Arik Dahan

Source: Pharmaceutics, Vol 14, Iss 3, p 675 (2022)

Subject Terms: inflammatory bowel disease, drug targeting, oral drug delivery, prodrug, cyclosporine, phospholipase A2, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/3/675; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/ce2b19224b9c4189b6e40db9f106c9c1