Therapeutic delivery of recombinant glucocerebrosidase enzyme-containing extracellular vesicles to human cells from Gaucher disease patients

Authors: Keatdamrong Janpipatkul, Nareerat Sutjarit, Amornrat Tangprasittipap, Tai Chaiamarit, Pawarit Innachai, Kanoknetr Suksen, Tanida Chokpanuwat, Thipwimol Tim-Aroon, Usanarat Anurathapan, Natee Jearawiriyapaisarn, Alisa Tubsuwan, Supareak Bowornpinyo, Nithi Asavapanumas, Arthit Chairoungdua, Kanit Bhukhai, Suradej Hongeng

Source: Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-14 (2024)

Subject Terms: Gaucher disease, Glucocerebrosidase, Extracellular vesicles, Macrophages, Neurons, Lentiviral vector, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/59a850ee25e242c784be1f2144fdcbd3

CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1

Authors: Wannisa Khamaikawin, Chonticha Saisawang, Boonrat Tassaneetrithep, Kanit Bhukhai, Phetcharat Phanthong, Suparerk Borwornpinyo, Angsana Phuphuakrat, Ekawat Pasomsub, Sujittra Chaisavaneeyakorn, Usanarat Anurathapan, Nopporn Apiwattanakul, Suradej Hongeng

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Subject Terms: CCR5 CRISPR/Cas9, C46 HIV-1 fusion inhibitor, HIV-1 gene therapy, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3964034463254bb8bbb9ab7dbff414ef

An increase in ER stress and unfolded protein response in iPSCs-derived neuronal cells from neuronopathic Gaucher disease patients

Authors: Tanapat Pornsukjantra, Nongluk Saikachain, Nareerat Sutjarit, Arthaporn Khongkrapan, Alisa Tubsuwan, Kanit Bhukhai, Thipwimol Tim-Aroon, Usanarat Anurathapan, Suradej Hongeng, Nithi Asavapanumas

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Subject Terms: Gaucher disease, iPSCs-derived neurons, ER stress, UPR, LSDs, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0f6e96ed824b4ccca62b25c09c125f40

Improving hematopoietic differentiation from human induced pluripotent stem cells by the modulation of Hippo signaling with a diarylheptanoid derivative

Authors: Umnuaychoke Thongsa-ad, Anongnat Wongpan, Wasinee Wongkummool, Phaewa Chaiwijit, Kwanchanok Uppakara, Gorawin Chaiyakitpattana, Passanan Singpant, Pirut Tong-ngam, Amnat Chukhan, Wachirachai Pabuprappap, Sirapope Wongniam, Apichart Suksamrarn, Suradej Hongeng, Usanarat Anurathapan, Kasem Kulkeaw, Alisa Tubsuwan, Kanit Bhukhai

Source: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-20 (2024)

Subject Terms: Diarylheptanoid, Human induced pluripotent stem cells, Primitive hematopoietic stem and progenitor cells, Hippo signaling pathway, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/1307d64570604af68cd78ca8bd7b61ed

HIV-1 proviral DNA in purified peripheral blood CD34+ stem and progenitor cells in individuals with long-term HAART; paving the way to HIV gene therapyKey points

Authors: Boonrat Tassaneetrithep, Angsana Phuphuakrat, Ekawat Pasomsub, Kanit Bhukhai, Wasinee Wongkummool, Thongkoon Priengprom, Wannisa Khamaikawin, Sujittra Chaisavaneeyakorn, Usanarat Anurathapan, Nopporn Apiwattanakul, Suradej Hongeng

Source: Heliyon, Vol 10, Iss 4, Pp e26613- (2024)

Subject Terms: HIV-1 infection, People living with HIV-1, Peripheral CD34+ HSPCs, Intact proviral DNA assay, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024026446; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/b397e8c13c164e05ae86e773686674f4

Establishment of MUi030-A: A human induced pluripotent stem cell line carrying homozygous L444P mutation in the GBA1 gene to study type-3 Gaucher disease

Authors: Kitsada Kangboonruang, Tanapat Pornsukjantra, Pirut Tong-Ngam, Tanida Chokpanuwat, Thipwimol Tim-Aroon, Duangrurdee Wattanasirichaigoon, Usanarat Anurathapan, Suradej Hongeng, Nithi Asavapanumas, Kanit Bhukhai, Alisa Tubsuwan

Source: Stem Cell Research, Vol 73, Iss , Pp 103229- (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506123002155; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/7d6440b83bd94cfe949e746889387da2

Neuropilin-1 cooperates with PD-1 in CD8+ T cells predicting outcomes in melanoma patients treated with anti-PD1

Authors: Julien Rossignol, Zakia Belaid, Guillemette Fouquet, Flavia Guillem, Rachel Rignault, Pierre Milpied, Amédée Renand, Tereza Coman, Maud D’Aveni, Michael Dussiot, Elia Colin, Jonathan Levy, Caroline Carvalho, Nicolas Goudin, Nicolas Cagnard, Francine Côté, Joel Babdor, Kanit Bhukhai, Laura Polivka, Amélie E. Bigorgne, Héloise Halse, Aurélien Marabelle, Séverine Mouraud, Yves Lepelletier, Thiago T. Maciel, Marie-Thérèse Rubio, Delphine Heron, Caroline Robert, Isabelle Girault, Doris Lebeherec, Jean-Yves Scoazec, Ivan Moura, Louise Condon, Mirjana Weimershaus, Franck Pages, Jean Davoust, David Gross, Olivier Hermine

Source: iScience, Vol 25, Iss 6, Pp 104353- (2022)

Subject Terms: Immunology, Cancer, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222006241; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/f5e6f0c742664340a9161e17f5444749

A generation of human induced pluripotent stem cell line (MUi031-A) from a type-3 Gaucher disease patient carrying homozygous mutation on GBA1 gene

Authors: Tanapat Pornsukjantra, Kitsada Kangboonruang, Pirut Tong-Ngam, Thipwimol Tim-Aroon, Duangrurdee Wattanasirichaigoon, Usanarat Anurathapan, Suradej Hongeng, Alisa Tubsuwan, Kanit Bhukhai, Nithi Asavapanumas

Source: Stem Cell Research, Vol 60, Iss , Pp 102698- (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506122000472; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/473a8ab9e4dd4d03953ac06bf76f6fbd

Erythrocytosis associated with IgA nephropathy

Authors: Camille Cohen, Séverine Coulon, Kanit Bhukhai, Antoine Neuraz, Michael Dussiot, Guillemette Fouquet, Marie-Bénédicte Le Stang, Martin Flamant, François Vrtovsnik, Aurélie Hummel, Bertrand Knebelmann, Laurent Mesnard, Eric Rondeau, Thiago T. Maciel, Fabrizia Favale, Nicole Casadevall, Thao Nguyen-Khoa, Stéphane Moutereau, Christophe Legendre, Marc Benhamou, Renato C. Monteiro, Olivier Hermine, Khalil El Karoui, Ivan C. Moura

Source: EBioMedicine, Vol 75, Iss , Pp 103785- (2022)

Subject Terms: IgA, IgA nephropathy, Erythrocytosis, Polycythemia, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235239642100579X; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/736d119de1ba4bb9b49d07811c31cf55

The Future of Gene Therapy for Transfusion-Dependent Beta-Thalassemia: The Power of the Lentiviral Vector for Genetically Modified Hematopoietic Stem Cells

Authors: Parin Rattananon, Usanarat Anurathapan, Kanit Bhukhai, Suradej Hongeng

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: β-thalassemia, hematopoietic stem cells (HSCs), gene therapy, lentiviral vector, transfusion-dependent, allogeneic HSC transplantation, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.730873/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/9b0bc4e756c44979b067202db03017e6

Enhancing Erythropoiesis by a Phytoestrogen Diarylheptanoid from Curcuma comosa

Authors: Kanit Bhukhai, Guillemette Fouquet, Yutthana Rittavee, Nopmullee Tanhuad, Chaiyaporn Lakmuang, Suparerk Borwornpinyo, Usanarat Anurathapan, Apichart Suksamrarn, Pawinee Piyachaturawat, Arthit Chairoungdua, Olivier Hermine, Suradej Hongeng

Source: Biomedicines, Vol 10, Iss 6, p 1427 (2022)

Subject Terms: anemia, erythropoiesis, erythropoietin receptor signaling, diarylheptanoid, phytoestrogen, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/6/1427; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/13bee47eb76d46ba96521c203fbba1dc

Potential Application of Gambogic Acid for Retarding Renal Cyst Progression in Polycystic Kidney Disease

Authors: Nutchanard Khunpatee, Kanit Bhukhai, Varanuj Chatsudthipong, Chaowalit Yuajit

Source: Molecules, Vol 27, Iss 12, p 3837 (2022)

Subject Terms: gambogic acid, MDCK cyst growth, ERK1/2, S6K, AMPK, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/12/3837; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/81d414e2c21c4108ae9f6606271b1461

Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2

Authors: Chotiwat Seephetdee, Nattawut Buasri, Kanit Bhukhai, Kitima Srisanga, Suwimon Manopwisedjaroen, Sarat Lertjintanakit, Nut Phueakphud, Chatbenja Pakiranay, Niwat Kangwanrangsan, Sirawat Srichatrapimuk, Suppachok Kirdlarp, Somnuek Sungkanuparph, Somchai Chutipongtanate, Arunee Thitithanyanont, Suradej Hongeng, Patompon Wongtrakoongate

Source: Vaccines, Vol 9, Iss 5, p 498 (2021)

Subject Terms: HexaPro, spike, SARS-CoV-2, vaccine, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/9/5/498; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/9e133e4f2cfe4a6fb3f21915c3c897cb

The Bioactive Peptide SL-13R Expands Human Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells In Vitro

Authors: Takenobu Nii, Katsuhiro Konno, Masaki Matsumoto, Kanit Bhukhai, Suparerk Borwornpinyo, Kazuhiro Sakai, Suradej Hongeng, Daisuke Sugiyama

Source: Molecules, Vol 26, Iss 7, p 1995 (2021)

Subject Terms: umbilical cord blood, hematopoietic stem/progenitor cell, peptide, cell culture, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/7/1995; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/37f7a2ccf8844156b47423597bf7979e

Current and future alternative therapies for beta-thalassemia major

Authors: Edouard de Dreuzy, Kanit Bhukhai, Philippe Leboulch, Emmanuel Payen

Source: Biomedical Journal, Vol 39, Iss 1, Pp 24-38 (2016)

Subject Terms: Beta-thalassemia, Allogeneic transplantation, Beta-globin, Gene therapy, Gamma-globin inducers, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2319417016000172; https://doaj.org/toc/2319-4170

Access URL: https://doaj.org/article/7dd31e8bb0664f8a86c02b6bd1351dc2

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