Antibodies against ARHGDIB are associated with long-term kidney graft loss

Authors: Kamburova, Elena G., Gruijters, Maartje L., Kardol-Hoefnagel, Tineke, Wisse, Bram W., Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., van Reekum, Franka E., van Zuilen, Arjan D., Verhaar, Marianne C., Bots, Michiel L., Drop, Adriaan C.A.D., Plaisier, Loes, Melchers, Rowena C.A., Seelen, Marc A.J., Sanders, Jan Stephan, Hepkema, Bouke G., Lambeck, Annechien J.A., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G.J., Voorter, Christina E., Wieten, Lotte, van Duijnhoven, Elly M., Gelens, Mariëlle A.C.J., Christiaans, Maarten H.L., van Ittersum, Frans J., Nurmohamed, Shaikh A., Lardy, Neubury M., Swelsen, Wendy, van der Pant, Karlijn A.M.I., van der Weerd, Neelke C., ten Berge, Ineke J.M., Hoitsma, Andries, van der Boog, Paul J.M., de Fijter, Johan W., Betjes, Michiel G.H., Heidt, Sebastiaan, Roelen, Dave L., Claas, Frans H., Bemelman, Frederike J., Otten, Henny G. ^*

Source: In American Journal of Transplantation December 2019 19(12):3335-3344

Results and reflections from the PROfiling Consortium on Antibody Repertoire and Effector functions in kidney transplantation: A mini‐review

Authors: Kamburova, Elena G., Hoitsma, Andries, Claas, Frans H., Otten, Henny G.

Source: Tissue antigens. 94(2):129-140

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085842217.0x000001&indx=1&recIds=ETOCvdc_100085842217.0x000001

Allocation to highly sensitized patients based on acceptable mismatches results in low rejection rates comparable to nonsensitized patients

Authors: Heidt, Sebastiaan, Haasnoot, Geert W., Witvliet, Marian D., Linden‐van Oevelen, Marissa J. H., Kamburova, Elena G., Wisse, Bram W., Joosten, Irma, Allebes, Wil A., Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., Reekum, Franka E., Zuilen, Arjan D., Verhaar, Marianne C., Bots, Michiel L., Drop, Adriaan C. A. D., Plaisier, Loes, Seelen, Marc A. J., Sanders, Jan‐Stephan, Hepkema, Bouke G., Lambeck, Annechien J. A., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G. J., Voorter, Christina E., Wieten, Lotte, Duijnhoven, Elly M., Gelens, Marielle A.C.J., Christiaans, Maarten H. L., Ittersum, Frans J., Nurmohamed, Shaikh A., Lardy, Neubury M., Swelsen, Wendy, Pant, Karlijn A. M. I., Weerd, Neelke C., ten Berge, Ineke J. M., Bemelman, Frederike J., Hoitsma, Andries, Boog, Paul J. M., Fijter, Johan W., Betjes, Michiel G. H., Otten, Henny G., Roelen, Dave L., Claas, Frans H. J.

Source: American journal of transplantation. 19(10):2926-2933

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091975909.0x000001&indx=1&recIds=ETOCvdc_100091975909.0x000001

Determination of the clinical relevance of donor epitope‐specific HLA‐antibodies in kidney transplantation.

Authors: Kardol‐Hoefnagel, Tineke, Senejohnny, Danial Mohammadi, Kamburova, Elena G., Wisse, Bram W., Reteig, Leon, Gruijters, Maartje L., Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., van Reekum, Franka E., van Zuilen, Arjan D., Verhaar, Marianne C., Bots, Michiel L., Drop, Adriaan C. A. D., Plaisier, Loes, Melchers, Rowena C. A.

Source: HLA: Immune Response Genetics; Jan2024, Vol. 103 Issue 1, p1-14, 14p

Subject Terms: IMMUNOGLOBULINS, DEAD, KIDNEY transplantation, GRAFT survival, ANTIGEN analysis, SURVIVAL rate, HLA-DR antigens

Ellipro scores of donor epitope specific HLA antibodies are not associated with kidney graft survival.

Authors: Kardol‐Hoefnagel, Tineke, Senejohnny, Danial Mohammadi, Kamburova, Elena G., Wisse, Bram W., Gruijters, Maartje L., Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., van Reekum, Franka E., van Zuilen, Arjan D., Verhaar, Marianne C., Drop, Adriaan C. A. D., Plaisier, Loes, Melchers, Rowena C. A., Seelen, Marc A. J., Sanders, Jan Stephan

Source: HLA: Immune Response Genetics; Jan2024, Vol. 103 Issue 1, p1-6, 6p

Subject Terms: IMMUNOGLOBULINS, GRAFT survival, KIDNEYS, KIDNEY transplantation

The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production

Authors: Smeekens, Sanne P., van den Hoogen, Martijn W.F., Kamburova, Elena G., van de Veerdonk, Frank L., Joosten, Irma, Koenen, Hans J.M.P., Netea, Mihai G., Hilbrands, Luuk B., Joosten, Leo A.B.

Source: In Transplant Immunology June 2013 28(4):183-188

T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation.

Authors: Peereboom, Emma T. M., Matern, Benedict M., Tomosugi, Toshihide, Niemann, Matthias, Drylewicz, Julia, Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., van Reekum, Franka E., Verhaar, Marianne C., Kamburova, Elena G., Seelen, Marc A. J., Sanders, Jan Stephan, Hepkema, Bouke G., Lambeck, Annechien J., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G. J.

Source: Frontiers in Immunology; 11/18/2021, Vol. 12, p1-13, 13p

Subject Terms: T cells, KIDNEY transplantation, EPITOPES, KIDNEY failure, BIOMARKERS, PSYCHONEUROIMMUNOLOGY

Longitudinal Analysis of T and B Cell Phenotype and Function in Renal Transplant Recipients with or without Rituximab Induction Therapy.

Authors: Kamburova, Elena G.¹, Koenen, Hans J. P. M.¹, van den Hoogen, Martijn W. F.², Baas, Marije C.², Joosten, Irma¹, Hilbrands, Luuk B.²

Source: PLoS ONE. Nov2014, Vol. 9 Issue 11, p1-8. 8p.

Subject Terms: *B cells, *T cells, *PHENOTYPES, *KIDNEY transplantation, *RITUXIMAB, *IMMUNOSUPPRESSIVE agents

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Antibodies Against ARHGDIB and ARHGDIBGene Expression Associate With Kidney Allograft Outcome

Authors: Senev, Aleksandar, Otten, Henny G., Kamburova, Elena G., Callemeyn, Jasper, Lerut, Evelyne, Van Sandt, Vicky, Kuypers, Dirk, Emonds, Marie-Paule, Naesens, Maarten

Source: Transplantation; July 2020, Vol. 104 Issue: 7 p1462-1471, 10p

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Effect of initial immunosuppression on long-term kidney transplant outcome in immunological low-risk patients.

Authors: Michielsen, Laura A, Zuilen, Arjan D van, Verhaar, Marianne C, Wisse, Bram W, Kamburova, Elena G, Joosten, Irma, Allebes, Wil A, van der Meer, Arnold, Baas, Marije C, Spierings, Eric, Hack, Cornelis E, Reekum, Franka E van, Bots, Michiel L, Drop, Adriaan C A D, Plaisier, Loes, Seelen, Marc A J, Sanders, Jan-Stephan F, Hepkema, Bouke G, Lambeck, Annechien J, Bungener, Laura B

Source: Nephrology Dialysis Transplantation; Aug2019, Vol. 34 Issue 8, p1417-1422, 6p, 1 Diagram, 2 Charts, 1 Graph

Subject Terms: KIDNEY transplantation

Geographic Terms: NETHERLANDS

paired kidney analysis on the impact of pre-transplant anti-HLA antibodies on graft survival.

Authors: Michielsen, Laura A, Wisse, Bram W, Kamburova, Elena G, Verhaar, Marianne C, Joosten, Irma, Allebes, Wil A, van der Meer, Arnold, Hilbrands, Luuk B, Baas, Marije C, Spierings, Eric, Hack, Cornelis E, Reekum, Franka E van, Bots, Michiel L, Drop, Adriaan C A D, Plaisier, Loes, Seelen, Marc A J, Sanders, Jan-Stephan F, Hepkema, Bouke G, Lambeck, Annechien J, Bungener, Laura B

Source: Nephrology Dialysis Transplantation; Jun2019, Vol. 34 Issue 6, p1056-1063, 8p, 1 Diagram, 2 Charts, 2 Graphs

Subject Terms: IMMUNOGLOBULINS, KIDNEYS, KIDNEY transplantation

Toward a Sensible Single-antigen Bead Cutoff Based on Kidney Graft Survival.

Authors: Wisse, Bram W., Kamburova, Elena G., Joosten, Irma, Allebes, Wil A., van der Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., van Reekum, Franka E., van Zuilen, Arjan D., Verhaar, Marianne C., Bots, Michiel L., Drop, Adriaan C.A.D., Plaisier, Loes, Seelen, Marc A.J., Stephan Sanders, Jan, Hepkema, Bouke G., Lambeck, Annechien J.A., Bungener, Laura B.

Source: Transplantation; Apr2019, Vol. 103 Issue 4, p789-797, 9p

Antibodies against ARHGDIBare associated with long‐term kidney graft loss

Authors: Kamburova, Elena G., Gruijters, Maartje L., Kardol‐Hoefnagel, Tineke, Wisse, Bram W., Joosten, Irma, Allebes, Wil A., Meer, Arnold, Hilbrands, Luuk B., Baas, Marije C., Spierings, Eric, Hack, Cornelis E., Reekum, Franka E., Zuilen, Arjan D., Verhaar, Marianne C., Bots, Michiel L., Drop, Adriaan C. A. D., Plaisier, Loes, Melchers, Rowena C. A., Seelen, Marc A. J., Sanders, Jan Stephan, Hepkema, Bouke G., Lambeck, Annechien J. A., Bungener, Laura B., Roozendaal, Caroline, Tilanus, Marcel G. J., Voorter, Christina E., Wieten, Lotte, Duijnhoven, Elly M., Gelens, Mariëlle A. C. J., Christiaans, Maarten H. L., van Ittersum, Frans J., Nurmohamed, Shaikh A., Lardy, Neubury M., Swelsen, Wendy, Pant, Karlijn A. M. I., Weerd, Neelke C., Berge, Ineke J. M., Hoitsma, Andries, Boog, Paul J. M., de Fijter, Johan W., Betjes, Michiel G. H., Heidt, Sebastiaan, Roelen, Dave L., Claas, Frans H., Bemelman, Frederike J., Otten, Henny G.

Source: American Journal of Transplantation; December 2019, Vol. 19 Issue: 12 p3335-3344, 10p

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Type of rejection and biopsy findings after induction therapy with a single dose of rituximab

Authors: van den Hoogen, Martijn W.F., Kamburova, Elena G., Baas, Marije C., Steenbergen, Eric J., Florquin, Sandrine, Koenen, Hans J.P.M., Joosten, Irma, Hilbrands, Luuk B.

Source: In Transplant Immunology October 2014 31(4):222-222

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