Systems metabolic engineering of the primary and secondary metabolism of Streptomyces albidoflavus enhances production of the reverse antibiotic nybomycin against multi-resistant Staphylococcus aureus

Authors: Stegmüller, Julian, Rodríguez Estévez, Marta, Shu, Wei, Gläser, Lars, Myronovskyi, Maksym, Rückert-Reed, Christian, Kalinowski, Jörn, Luzhetskyy, Andriy, Wittmann, Christoph

Source: In Metabolic Engineering January 2024 81:123-143

The MerR‐family regulator NmlR is involved in the defense against oxidative stress in Streptococcus pneumoniae

Authors: Fritsch, Verena Nadin, Linzner, Nico, Busche, Tobias, Said, Nelly, Weise, Christoph, Kalinowski, Jörn, Wahl, Markus C., Antelmann, Haike

Source: Molecular microbiology. 119(2):191-207

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182089087.0x000001&indx=1&recIds=ETOCvdc_100182089087.0x000001

Free-floating extracellular DNA (exDNA) in different wastewaters: Status quo on exDNA-associated antimicrobial resistance genes

Authors: Savin, Mykhailo, Hammerl, Jens Andre, Hassa, Julia, Hembach, Norman, Kalinowski, Jörn, Schwartz, Thomas, Droop, Felix, Mutters, Nico T.

Source: In Environmental Pollution 15 November 2023 337

Staphylococcus aureus adapts to the immunometabolite itaconic acid by inducing acid and oxidative stress responses including S-bacillithiolations and S-itaconations

Authors: Loi, Vu Van, Busche, Tobias, Kuropka, Benno, Müller, Susanne, Methling, Karen, Lalk, Michael, Kalinowski, Jörn, Antelmann, Haike

Source: In Free Radical Biology and Medicine 1 November 2023 208:859-876

Sézary Syndrome Shows Whole Genome Duplication as a Late Event in Tumor Evolution

Authors: Hain, Carsten, Stadler, Rudolf, Kalinowski, Jörn

Source: Journal of investigative dermatology. 142(6):1755-1758

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163665192.0x000001&indx=1&recIds=ETOCvdc_100163665192.0x000001

T-Cell Receptor Rearrangements in Early Stages of Mycosis Fungoides May Be Associated with Pronounced Copy Number Variations: A Prognostic Factor?

Authors: Hain, Carsten, Cieslak, Cassandra, Kalinowski, Jörn, Stadler, Rudolf

Source: Cancers; Feb2025, Vol. 17 Issue 3, p556, 7p

Subject Terms: T cells, GENOMICS, MYCOSIS fungoides, DESCRIPTIVE statistics, DECISION making in clinical medicine, GENETIC variation, GENE expression profiling, CHROMOSOMES, GENETIC mutation, EARLY diagnosis, TUMOR classification, CELL receptors, SENSITIVITY & specificity (Statistics), SEQUENCE analysis, DISEASE progression

Targeting Transcriptional Regulators Affecting Acarbose Biosynthesis in Actinoplanes sp. SE50/110 Using CRISPRi Silencing.

Authors: Dymek, Saskia, Jacob, Lucas, Pühler, Alfred, Kalinowski, Jörn

Source: Microorganisms; Jan2025, Vol. 13 Issue 1, p1, 16p

Subject Terms: REGULATOR genes, TYPE 2 diabetes, GENE silencing, CRISPRS, ACARBOSE

Evaluation of virulence potential of methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates from a German refugee cohort

Authors: Creutz, Ines, Busche, Tobias, Layer, Franziska, Bednarz, Hanna, Kalinowski, Jörn, Niehaus, Karsten

Source: In Travel Medicine and Infectious Disease January-February 2022 45

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli

Authors: Rust, Michael, Helfrich, Eric J. N., Freeman, Michael F., Nanudorn, Pakjira, Field, Christopher M., Rückert, Christian, Kündig, Tomas, Page, Michael J., Webb, Victoria L., Kalinowski, Jörn, Sunagawa, Shinichi, Piel, Jörn

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Apr . 117(17), 9508-9518.

Access URL: https://www.jstor.org/stable/26929958

The two-Cys-type TetR repressor GbaA confers resistance under disulfide and electrophile stress in Staphylococcus aureus

Authors: Van Loi, Vu, Busche, Tobias, Fritsch, Verena Nadin, Weise, Christoph, Gruhlke, Martin Clemens Horst, Slusarenko, Alan John, Kalinowski, Jörn, Antelmann, Haike

Source: In Free Radical Biology and Medicine December 2021 177:120-131

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

Authors: Altmüller, Janine, Angelov, Angel, Aschenbrenner, Anna C., Bals, Robert, Bartholomäus, Alexander, Becker, Anke, Becker, Matthias, Bezdan, Daniela, Bitzer, Michael, Blumert, Conny, Bonifacio, Ezio, Bork, Peer, Boyke, Bunk, Blum, Helmut, Casadei, Nicolas, Clavel, Thomas, Colome-Tatche, Maria, Cornberg, Markus, De La Rosa Velázquez, Inti Alberto, Diefenbach, Andreas, Dilthey, Alexander, Fischer, Nicole, Förstner, Konrad, Franzenburg, Sören, Frick, Julia-Stefanie, Gabernet, Gisela, Gagneur, Julien, Ganzenmueller, Tina, Gauder, Marie, Geißert, Janina, Goesmann, Alexander, Göpel, Siri, Grundhoff, Adam, Grundmann, Hajo, Hain, Torsten, Hanses, Frank, Hehr, Ute, Heimbach, André, Hoeper, Marius, Horn, Friedemann, Hübschmann, Daniel, Hummel, Michael, Iftner, Thomas, Iftner, Angelika, Illig, Thomas, Janssen, Stefan, Kalinowski, Jörn, Kallies, René, Kehr, Birte, Keller, Andreas, Keppler, Oliver T., Kim-Hellmuth, Sarah, Klein, Christoph, Knop, Michael, Kohlbacher, Oliver, Köhrer, Karl, Korbel, Jan, Kremsner, Peter G., Kühnert, Denise, Kurth, Ingo, Landthaler, Markus, Li, Yang, Ludwig, Kerstin U., Makarewicz, Oliwia, Marini, Federico, Marz, Manja, McHardy, Alice C., Mertes, Christian, Münchhoff, Maximilian, Nahnsen, Sven, Nöthen, Markus, Ntoumi, Francine, Nürnberg, Peter, Ossowski, Stephan, Overmann, Jörg, Peter, Silke, Pfeffer, Klaus, Pink, Isabell, Poetsch, Anna R., Protzer, Ulrike, Pühler, Alfred, Rajewsky, Nikolaus, Ralser, Markus, Reiche, Kristin, Rieß, Olaf, Ripke, Stephan, Nunes da Rocha, Ulisses, Rosenstiel, Philip, Saliba, Antoine-Emmanuel, Sander, Leif Erik, Sawitzki, Birgit, Scheithauer, Simone, Schiffer, Philipp, Schmid-Burgk, Jonathan, Schneider, Wulf, Schulte, Eva-Christina, Schultze, Joachim L., Sczyrba, Alexander, Sharaf, Mariam L., Singh, Yogesh, Sonnabend, Michael, Stegle, Oliver, Stoye, Jens, Theis, Fabian, Ulas, Thomas, Vehreschild, Janne, Velavan, Thirumalaisamy P., Vogel, Jörg, Volland, Sonja, von Kleist, Max, Walker, Andreas, Walter, Jörn, Wieczorek, Dagmar, Winkler, Sylke, Ziebuhr, John, Krämer, Benjamin, Knoll, Rainer, Bonaguro, Lorenzo, ToVinh, Michael, Raabe, Jan, Astaburuaga-García, Rosario, Schulte-Schrepping, Jonas, Kaiser, Kim Melanie, Rieke, Gereon J., Bischoff, Jenny, Monin, Malte B., Hoffmeister, Christoph, Schlabe, Stefan, De Domenico, Elena, Reusch, Nico, Händler, Kristian, Reynolds, Gary, Blüthgen, Nils, Hack, Gudrun, Finnemann, Claudia, Nischalke, Hans D., Strassburg, Christian P., Stephenson, Emily, Su, Yapeng, Gardner, Louis, Yuan, Dan, Chen, Daniel, Goldman, Jason, Rosenstiel, Philipp, Schmidt, Susanne V., Latz, Eicke, Hrusovsky, Kevin, Ball, Andrew J., Johnson, Joe M., Koenig, Paul-Albert, Schmidt, Florian I., Haniffa, Muzlifah, Heath, James R., Kümmerer, Beate M., Keitel, Verena, Jensen, Björn, Stubbemann, Paula, Kurth, Florian, Sander, Leif E., Nattermann, Jacob

Source: In Immunity 9 November 2021 54(11):2650-2669

The linear plasmid pSA3239 is essential for the replication of the Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome

Authors: Novakova, Renata, Rückert, Christian, Knirschova, Renata, Feckova, Lubomira, Busche, Tobias, Csolleiova, Dominika, Homerova, Dagmar, Rezuchova, Bronislava, Javorova, Rachel, Sevcikova, Beatrica, Kalinowski, Jörn, Kormanec, Jan

Source: In Research in Microbiology September-October 2021 172(6)

A targeted transcriptomics approach for the determination of mixture effects of pesticides

Authors: Lichtenstein, Dajana, Mentz, Almut, Sprenger, Heike, Schmidt, Felix F., Albaum, Stefan P., Kalinowski, Joern, Planatscher, Hannes, Joos, Thomas O., Poetz, Oliver, Braeuning, Albert ^*

Source: In Toxicology August 2021 460

Recombinant expression and characterization of novel P450s from Actinosynnema mirum

Authors: Schmitz, Lisa Marie, Hageneier, Felix, Rosenthal, Katrin, Busche, Tobias, Brandt, David, Kalinowski, Jörn, Lütz, Stephan

Source: In Bioorganic & Medicinal Chemistry 15 July 2021 42

An eight-compound mixture but not corresponding concentrations of individual chemicals induces triglyceride accumulation in human liver cells

Authors: Lichtenstein, Dajana, Lasch, Alexandra, Alarcan, Jimmy, Mentz, Almut, Kalinowski, Jörn, Schmidt, Felix F., Pötz, Oliver, Marx-Stoelting, Philip, Braeuning, Albert ^*

Source: In Toxicology July 2021 459

Pesticide mixture effects on liver protein abundance in HepaRG cells

Authors: Schmidt, Felix F., Lichtenstein, Dajana, Planatscher, Hannes, Mentz, Almut, Kalinowski, Joern, Steinhilber, Andreas E., Joos, Thomas O., Braeuning, Albert, Pötz, Oliver ^*

Source: In Toxicology 30 June 2021 458

New insights into the diversity and evolution of the archaeal mobilome from three complete genomes of Saccharolobus shibatae

Authors: Medvedeva, Sofia, Brandt, David, Cvirkaite‐Krupovic, Virginija, Liu, Ying, Severinov, Konstantin, Ishino, Sonoko, Ishino, Yoshizumi, Prangishvili, David, Kalinowski, Jörn, Krupovic, Mart

Source: Environmental microbiology. 23(8):4612-4630

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139820713.0x000001&indx=1&recIds=ETOCvdc_100139820713.0x000001

Microparticles enhance the formation of seven major classes of natural products in native and metabolically engineered actinobacteria through accelerated morphological development

Authors: Kuhl, Martin, Rückert, Christian, Gläser, Lars, Beganovic, Selma, Luzhetskyy, Andriy, Kalinowski, Jörn, Wittmann, Christoph

Source: Biotechnology and bioengineering. 118(8):3076-3093

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138896665.0x000001&indx=1&recIds=ETOCvdc_100138896665.0x000001

Genomic and proteomic profiles of biofilms on microplastics are decoupled from artificial surface properties

Authors: Oberbeckmann, Sonja, Bartosik, Daniel, Huang, Sixing, Werner, Johannes, Hirschfeld, Claudia, Wibberg, Daniel, Heiden, Stefan E., Bunk, Boyke, Overmann, Jörg, Becher, Dörte, Kalinowski, Jörn, Schweder, Thomas, Labrenz, Matthias, Markert, Stephanie

Source: Environmental microbiology. 23(6):3099-3115

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122630757.0x000001&indx=1&recIds=ETOCvdc_100122630757.0x000001

Genomic-Led Discovery of a Novel Glycopeptide Antibiotic by Nonomuraea coxensis DSM 45129

Authors: Yushchuk, Oleksandr, Vior, Natalia M., Andreo-Vidal, Andres, Berini, Francesca, Rückert, Christian, Busche, Tobias, Binda, Elisa, Kalinowski, Jörn, Truman, Andrew W., Marinelli, Flavia

Source: ACS chemical biology. 16(5):915-928

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626652807&indx=1&recIds=ETOCRN626652807