An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status

Authors: Takata, Hiroshi, Mitchell, Julie L., Pacheco, Julian, Pagliuzza, Amélie, Pinyakorn, Suteeraporn, Buranapraditkun, Supranee, Sacdalan, Carlo, Leyre, Louise, Nathanson, Sam, Kakazu, Juyeon C., Intasan, Jintana, Prueksakaew, Peeriya, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Haddad, Elias K., Rolland, Morgane, Tovanabutra, Sodsai, Vasan, Sandhya, Hsu, Denise C., Chomont, Nicolas, Trautmann, Lydie

Source: In Cell Host & Microbe 13 September 2023 31(9):1494-1506

Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8+ T cells

Authors: Teeratakulpisarn, Nipat, Pattanachaiwit, Supanit, Sriplienchan, Somchai, Tantivitayakul, Ponpen, Kanaprach, Ratchapong, Ruxrungtham, Kiat, Dumrongpisutikul, Netsiri, Rojnuckarin, Ponlapat, Chottanapund, Suthat, Poltavee, Kultida, Luekasemsuk, Tassanee, Savadsuk, Hathairat, Puttamsawin, Suwanna, Benjapornpong, Khunthalee, Ratnaratorn, Nisakorn, Tangnaree, Kamonkan, Munkong, Chutharat, Thaimanee, Rommanus, Eamyoung, Patcharin, Ubolyam, Sasiwimol, Lerdlum, Sukalya, Manasnayakorn, Sopark, Rerknimitr, Rugsun, Sirivichayakul, Sunee, Wattanaboonyongcharoen, Phandee, Cowden, Jessica, Schuetz, Alexandra, Akapirat, Siriwat, Churikanont, Nampueng, Getchalarat, Saowanit, Hsu, Denise, Turk, Ellen, Butterworth, Oratai, Milazzo, Mark, Eller, Leigh Anne, Ake, Julie, Spudich, Serena, Fox, CAPT Lawrence, Ratto-Kim, Silvia, DeGruttola, Victor, Chinvarun, Yotin, Sithinamsuwan, Pasiri, Fletcher, James, Shiramizu, Bruce, Takata, Hiroshi, Kakazu, Juyeon C., Mitchell, Julie L., Kroon, Eugene, Colby, Donn J., Sacdalan, Carlo, Bai, Hongjun, Ehrenberg, Philip K., Geretz, Aviva, Buranapraditkun, Supranee, Pinyakorn, Suteeraporn, Intasan, Jintana, Tipsuk, Somporn, Suttichom, Duanghathai, Prueksakaew, Peeriya, Chalermchai, Thep, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Michael, Nelson L., Robb, Merlin L., Haddad, Elias K., Crowell, Trevor A, Vasan, Sandhya, Valcour, Victor G., Douek, Daniel C., Thomas, Rasmi, Rolland, Morgane, Chomont, Nicolas, Ananworanich, Jintanat, Trautmann, Lydie

Source: In eBioMedicine October 2022 84

Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS.

Authors: Sarabia, Indra, Novis, Camille L., Macedo, Amanda B., Takata, Hiroshi, Nell, Racheal, Kakazu, Juyeon C., Furler, Robert L., Shakya, Binita, Schubert, Heidi L., Hill, Christopher P., DePaula-Silva, Ana Beatriz, Spivak, Adam M., Trautmann, Lydie, Planelles, Vicente, Bosque, Alberto

Source: Frontiers in Immunology; 6/14/2021, Vol. 12, p1-18, 18p

Subject Terms: HIV, VIRUS diseases, MITOCHONDRIA, CELL death, T cells, NATURAL immunity, CELL communication