Penetrance of Parkinson's Disease in LRRK2 p.G2019S Carriers Is Modified by a Polygenic Risk Score

Authors: Iwaki, Hirotaka, Blauwendraat, Cornelis, Makarious, Mary B., Bandrés‐Ciga, Sara, Leonard, Hampton L., Gibbs, J. Raphael, Hernandez, Dena G., Scholz, Sonja W., Faghri, Faraz, Nalls, Mike A., Singleton, Andrew B., Noyce, Alastair J, Kaiyrzhanov, Rauan, Middlehurst, Ben, Kia, Demis A, Tan, Manuela, Houlden, Henry, Morris, Huw R, Plun‐Favreau, Helene, Holmans, Peter, Hardy, John, Trabzuni, Daniah, Quinn, John, Bubb, Vivien, Mok, Kin Y, Kinghorn, Kerri J., Wood, Nicholas W, Lewis, Patrick, Schreglmann, Sebastian, Lovering, Ruth, R'Bibo, Lea, Manzoni, Claudia, Rizig, Mie, Ryten, Mina, Guelfi, Sebastian, Escott‐Price, Valentina, Chelban, Viorica, Foltynie, Thomas, Williams, Nigel, Morrison, Karen E., Clarke, Carl, Brice, Alexis, Danjou, Fabrice, Lesage, Suzanne, Corvol, Jean‐Christophe, Martinez, Maria, Schulte, Claudia, Brockmann, Kathrin, Simón‐Sánchez, Javier, Heutink, Peter, Rizzu, Patrizia, Sharma, Manu, Gasser, Thomas, Cookson, Mark R, Bandres‐Ciga, Sara, Craig, David W., Billingsley, Kimberley, Narendra, Derek, Raphael Gibbs, J, Keuren‐Jensen, Kendall Van, Shulman, Joshua M., Robak, Laurie, Bras, Jose, Guerreiro, Rita, Lubbe, Steven, Finkbeiner, Steven, Mencacci, Niccolo E., Lungu, Codrin, Singleton, Andrew B, Reed, Xylena, Alcalay, Roy N., Gan‐Or, Ziv, Rouleau, Guy A., Krohn, Lynne, Hilten, Jacobus J, Marinus, Johan, Adarmes‐Gómez, Astrid D., Aguilar, Miquel, Alvarez, Ignacio, Alvarez, Victoria, Barrero, Francisco Javier, Yarza, Jesús Alberto Bergareche, Bernal‐Bernal, Inmaculada, Blazquez, Marta, Bonilla‐Toribio, Marta, Botía, Juan A., Boungiorno, María Teresa, Buiza‐Rueda, Dolores, Cámara, Ana, Carrillo, Fátima, Carrión‐Claro, Mario, Cerdan, Debora, Clarimón, Jordi, Compta, Yaroslau, Diez‐Fairen, Monica, Dols‐Icardo, Oriol, Duarte, Jacinto, Duran, Raquel, Escamilla‐Sevilla, Francisco, Ezquerra, Mario, Feliz, Cici, Fernández, Manel, Fernández‐Santiago, Rubén, Garcia, Ciara, García‐Ruiz, Pedro, Gómez‐Garre, Pilar, Heredia, Maria Jose Gomez, Gonzalez‐Aramburu, Isabel, Pagola, Ana Gorostidi, Hoenicka, Janet, Infante, Jon, Jesús, Silvia, Jimenez‐Escrig, Adriano, Kulisevsky, Jaime, Labrador‐Espinosa, Miguel A., Lopez‐Sendon, Jose Luis, Munain Arregui, Adolfo López, Macias, Daniel, Torres, Irene Martínez, Marín, Juan, Marti, Maria Jose, Martínez‐Castrillo, Juan Carlos, Méndez‐del‐Barrio, Carlota, González, Manuel Menéndez, Mata, Marina, Mínguez, Adolfo, Mir, Pablo, Rezola, Elisabet Mondragon, Muñoz, Esteban, Pagonabarraga, Javier, Pastor, Pau, Errazquin, Francisco Perez, Periñán‐Tocino, Teresa, Ruiz‐Martínez, Javier, Ruz, Clara, Rodriguez, Antonio Sanchez, Sierra, María, Suarez‐Sanmartin, Esther, Tabernero, Cesar, Tartari, Juan Pablo, Tejera‐Parrado, Cristina, Tolosa, Eduard, Valldeoriola, Francesc, Vargas‐González, Laura, Vela, Lydia, Vives, Francisco, Zimprich, Alexander, Pihlstrom, Lasse, Toft, Mathias, Koks, Sulev, Taba, Pille, Hassin‐Baer, Sharon, Majamaa, Kari, Siitonen, Ari, Tienari, Pentti, Okubadejo, Njideka U., Ojo, Oluwadamilola O., Kaiyrzhanov, Coordinator ‐ Rauan, Shashkin, Chingiz, Zharkinbekova, Nazira, Akhmetzhanov, Vadim, Aitkulova, Akbota, Zholdybayeva, Elena, Zharmukhanov, Zharkyn, Kaishybayeva, Gulnaz, Karimova, Altynay, Sadykova, Dinara

Source: Movement disorders. 35(5):774-780

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107197734.0x000001&indx=1&recIds=ETOCvdc_100107197734.0x000001