Prediction of resistance to bevacizumab plus FOLFOX in metastatic colorectal cancer-Results of the prospective multicenter PERMAD trial.

Authors: Thomas Seufferlein, Ludwig Lausser, Alexander Stein, Dirk Arnold, Gerald Prager, Stefan Kasper-Virchow, Michael Niedermeier, Lothar Müller, Stefan Kubicka, Alexander König, Petra Büchner-Steudel, Kai Wille, Andreas W Berger, Angelika M R Kestler, Johann M Kraus, Silke D Werle, Lukas Perkhofer, Thomas J Ettrich, Hans A Kestler

Source: PLoS ONE, Vol 19, Iss 6, p e0304324 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/70304decadfc447c8eecb19ea70285b5

Convalescent plasma treatment for SARS-CoV-2 infected high-risk patients: a matched pair analysis to the LEOSS cohort

Authors: Noemi F. Freise, Smaranda Gliga, Johannes Fischer, Nadine Lübke, Matthias Lutterbeck, Miriam Schöler, Edwin Bölke, Hans Martin Orth, Torsten Feldt, Christoph Roemmele, Dominik Wilke, Jochen Schneider, Kai Wille, Christian Hohmann, Richard Strauss, Martin Hower, Andreas Ruf, Joerg Schubert, Nora Isberner, Melanie Stecher, Lisa Pilgram, Jörg J. Vehreschild, LEOSS Study Group, Frank Hanses, Tom Luedde, Björn Jensen

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/2948c18af740438fb69cf9d409d8bd99

PB2187: ARTERIAL AND VENOUS THROMBOEMBOLIC COMPLICATIONS IN 832 PATIENTS WITH BCR-ABL-NEGATIVE MYELOPROLIFERATIVE NEOPLASMS (MPN)

Authors: Kai Wille, Eva Deventer, Parvis Sadjadian, Tatjana Becker, Vera Kolatzki, Karlo Hünerbein, Raphael Meixner, Hanna Marchi, Christiane Fuchs, Martin Griesshammer

Source: HemaSphere, Vol 7, p e9728155 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000975500.97281.55; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/0d87891a3d3e40988b5592e33d3bf2b2

Outcome of 129 Pregnancies in Polycythemia Vera Patients: A Report of the European LeukemiaNET

Authors: Kai Wille, Maja Brouka, Johannes Bernhardt, Axel Rüfer, Emilia Niculescu-Mizil, Mirjana Gotic, Susanne Isfort, Steffen Koschmieder, Tiziano Barbui, Parvis Sadjadian, Tatjana Becker, Vera Kolatzki, Raphael Meixner, Hannah Marchi, Christiane Fuchs, Frank Stegelmann, Konstanze Döhner, Jean-Jacques Kiladjian, Martin Griesshammer

Source: HemaSphere, Vol 7, Iss 5, p e882 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000882; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/b035eab057074d4ba4e409996281a096

Corrigendum to 'Machine Learning Based Prediction of COVID-19 Mortality Suggests Repositioning of Anticancer Drug for Treating Severe Cases'[Artificial Intelligence in Life Sciences] 1(2021), 100020

Authors: Thomas Linden, Frank Hanses, Daniel Domingo-Fernández, Lauren Nicole DeLong, Alpha Tom Kodamullil, Jochen Schneider, Maria J.G.T. Vehreschild, Julia Lanznaster, Maria Madeleine Ruethrich, Stefan Borgmann, Martin Hower, Kai Wille, Torsten Feldt, Siegbert Rieg, Bernd Hertenstein, Christoph Wyen, Christoph Roemmele, Jörg Janne Vehreschild, Carolin E.M. Jakob, Melanie Stecher, Maria Kuzikov, Andrea Zaliani, Holger Fröhlich

Source: Artificial Intelligence in the Life Sciences, Vol 2, Iss , Pp 100032- (2022)

Subject Terms: Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667318522000034; https://doaj.org/toc/2667-3185

Access URL: https://doaj.org/article/5a320d6d6a6f48538d8322230d437d85

Obesity and Impaired Metabolic Health Increase Risk of COVID-19-Related Mortality in Young and Middle-Aged Adults to the Level Observed in Older People: The LEOSS Registry

Authors: Norbert Stefan, Katrin Sippel, Martin Heni, Andreas Fritsche, Robert Wagner, Carolin E. M. Jakob, Hubert Preißl, Alexander von Werder, Yascha Khodamoradi, Stefan Borgmann, Maria Madeleine Rüthrich, Frank Hanses, Martina Haselberger, Christiane Piepel, Martin Hower, Jürgen vom Dahl, Kai Wille, Christoph Römmele, Janne Vehreschild, Melanie Stecher, Michele Solimena, Michael Roden, Annette Schürmann, Baptist Gallwitz, Martin Hrabe de Angelis, David S. Ludwig, Matthias B. Schulze, Bjoern Erik Ole Jensen, Andreas L. Birkenfeld

Source: Frontiers in Medicine, Vol 9 (2022)

Subject Terms: obesity, diabetes, hypertension, impaired metabolic health, mortality, COVID-19, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.875430/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/f99d511553474728bf4cf86f386a4ed5

Machine Learning Based Prediction of COVID-19 Mortality Suggests Repositioning of Anticancer Drug for Treating Severe Cases

Authors: Thomas Linden, Frank Hanses, Daniel Domingo-Fernández, Lauren Nicole DeLong, Alpha Tom Kodamullil, Jochen Schneider, Maria J.G.T. Vehreschild, Julia Lanznaster, Maria Madeleine Ruethrich, Stefan Borgmann, Martin Hower, Kai Wille, Torsten Feldt, Siegbert Rieg, Bernd Hertenstein, Christoph Wyen, Christoph Roemmele, Jörg Janne Vehreschild, Carolin E.M. Jakob, Melanie Stecher, Maria Kuzikov, Andrea Zaliani, Holger Fröhlich

Source: Artificial Intelligence in the Life Sciences, Vol 1, Iss , Pp 100020- (2021)

Subject Terms: Machine learning, Explainable ai, Precision medicine, Covid19, Drug repositioning, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667318521000209; https://doaj.org/toc/2667-3185

Access URL: https://doaj.org/article/f1ebf07fad2e486282bb8146b1b0d351

COVID-19 Severity and Thrombo-Inflammatory Response Linked to Ethnicity

Authors: Beate Heissig, Yousef Salama, Roman Iakoubov, Joerg Janne Vehreschild, Ricardo Rios, Tatiane Nogueira, Maria J. G. T. Vehreschild, Melanie Stecher, Hirotake Mori, Julia Lanznaster, Eisuke Adachi, Carolin Jakob, Yoko Tabe, Maria Ruethrich, Stefan Borgmann, Toshio Naito, Kai Wille, Simon Valenti, Martin Hower, Nobutaka Hattori, Siegbert Rieg, Tetsutaro Nagaoka, Bjoern-Erik Jensen, Hiroshi Yotsuyanagi, Bernd Hertenstein, Hideoki Ogawa, Christoph Wyen, Eiki Kominami, Christoph Roemmele, Satoshi Takahashi, Jan Rupp, Kazuhisa Takahashi, Frank Hanses, Koichi Hattori, on behalf of the LEOSS Study Group

Source: Biomedicines, Vol 10, Iss 10, p 2549 (2022)

Subject Terms: COVID-19 disease severity, cardiovascular disease, comorbidities, coagulation, inflammation, PSM, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/10/2549; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/34847be6412547e9a351db8920480279

Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease.

Authors: Sebastian Cremer, Lisa Pilgram, Alexander Berkowitsch, Melanie Stecher, Siegbert Rieg, Mariana Shumliakivska, Denisa Bojkova, Julian Uwe Gabriel Wagner, Galip Servet Aslan, Christoph Spinner, Guillermo Luxán, Frank Hanses, Sebastian Dolff, Christiane Piepel, Clemens Ruppert, Andreas Guenther, Maria Madeleine Rüthrich, Jörg Janne Vehreschild, Kai Wille, Martina Haselberger, Hanno Heuzeroth, Arne Hansen, Thomas Eschenhagen, Jindrich Cinatl, Sandra Ciesek, Stefanie Dimmeler, Stefan Borgmann, Andreas Zeiher, LEOSS study group

Source: PLoS ONE, Vol 16, Iss 10, p e0258684 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/7e234542cdff42628f85dca9a1f5a0e7

Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease

Authors: Sebastian Cremer, Lisa Pilgram, Alexander Berkowitsch, Melanie Stecher, Siegbert Rieg, Mariana Shumliakivska, Denisa Bojkova, Julian Uwe Gabriel Wagner, Galip Servet Aslan, Christoph Spinner, Guillermo Luxán, Frank Hanses, Sebastian Dolff, Christiane Piepel, Clemens Ruppert, Andreas Guenther, Maria Madeleine Rüthrich, Jörg Janne Vehreschild, Kai Wille, Martina Haselberger, Hanno Heuzeroth, Arne Hansen, Thomas Eschenhagen, Jindrich Cinatl, Sandra Ciesek, Stefanie Dimmeler, Stefan Borgmann, Andreas Zeiher, on behalf of the LEOSS study group

Source: PLoS ONE, Vol 16, Iss 10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530317/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b5baff8de9bf4e33b669346990756db5

Neoadjuvant plus adjuvant or only adjuvant nab-paclitaxel plus gemcitabine for resectable pancreatic cancer - the NEONAX trial (AIO-PAK-0313), a prospective, randomized, controlled, phase II study of the AIO pancreatic cancer group

Authors: Thomas J. Ettrich, Andreas W. Berger, Lukas Perkhofer, Severin Daum, Alexander König, Andreas Dickhut, Uwe Wittel, Kai Wille, Michael Geissler, Hana Algül, Eike Gallmeier, Jens Atzpodien, Marko Kornmann, Rainer Muche, Nicole Prasnikar, Andrea Tannapfel, Anke Reinacher-Schick, Waldemar Uhl, Thomas Seufferlein

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)

Subject Terms: Pancreatic ductal adenocarcinoma, Pancreatic cancer, Resectable, Neoadjuvant chemotherapy, Perioperative chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-5183-y; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/4b8d6fac7cb54c6aaa9dcd06f710f790