Multi-step regulation of microRNA expression and secretion into small extracellular vesicles by insulin

Authors: Lino, Marsel, Garcia-Martin, Ruben, Muñoz, Vitor Rosetto, Ruiz, Gabriel Palermo, Nawaz, Allah, Brandão, Bruna Brasil, Dreyfus, Jonathan, Pan, Hui, Kahn, C. Ronald

Source: In Cell Reports 23 July 2024 43(7)

Ketohexokinase-C regulates global protein acetylation to decrease carnitine palmitoyltransferase 1a-mediated fatty acid oxidation

Authors: Helsley, Robert N., Park, Se-Hyung, Vekaria, Hemendra J., Sullivan, Patrick G., Conroy, Lindsey R., Sun, Ramon C., Romero, María del Mar, Herrero, Laura, Bons, Joanna, King, Christina D., Rose, Jacob, Meyer, Jesse G., Schilling, Birgit, Kahn, C. Ronald, Softic, Samir

Source: Journal of hepatology. 79(1):25-42

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192577090.0x000001&indx=1&recIds=ETOCvdc_100192577090.0x000001

A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes

Authors: Girdhar, Khyati, Huang, Qian, Chow, I-Ting, Vatanen, Tommi, Brady, Claudia, Raisingani, Amol, Autissier, Patrick, Atkinson, Mark A., Kwok, William W., Kahn, C. Ronald, Altindis, Emrah

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Aug 01. 119(31), 1-12.

Access URL: https://www.jstor.org/stable/27172158

FoxK1 associated gene regulatory network in hepatic insulin action and its relationship to FoxO1 and insulin receptor mediated transcriptional regulation

Authors: Allu, Prasanna K.R., Cardamone, Maria Dafne, Gomes, Antonio S., Dall'agnese, Alessandra, Cederquist, Carly, Pan, Hui, Dreyfuss, Jonathan M., Enerbäck, Sven, Kahn, C. Ronald

Source: In Molecular Metabolism December 2023 78

Hepatic insulin receptor: new views on the mechanisms of liver disease

Authors: Lee, Wang-Hsin, Najjar, Sonia M., Kahn, C. Ronald, Hinds, Terry D., Jr

Source: In Metabolism August 2023 145

Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD

Authors: Park, Se-Hyung, Helsley, Robert N., Fadhul, Taghreed, Willoughby, Jennifer L.S., Noetzli, Leila, Tu, Ho-Chou, Solheim, Marie H., Fujisaka, Shiho, Pan, Hui, Dreyfuss, Jonathan M., Bons, Joanna, Rose, Jacob, King, Christina D., Schilling, Birgit, Lusis, Aldons J., Pan, Calvin, Gupta, Manoj, Kulkarni, Rohit N., Fitzgerald, Kevin, Kern, Philip A., Divanovic, Senad, Kahn, C. Ronald, Softic, Samir

Source: In Metabolism August 2023 145

Extracellular miRNAs as mediators of obesity‐associated disease

Authors: Brandao, Bruna Brasil, Lino, Marsel, Kahn, C. Ronald

Source: Journal of physiology. 600(5):1155-1169

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142289184.0x000001&indx=1&recIds=ETOCvdc_100142289184.0x000001

Insulin action in the brain: cell types, circuits, and diseases

Authors: Chen, Wenqiang, Cai, Weikang, Hoover, Benjamin, Kahn, C. Ronald

Source: Trends in neurosciences. 45(5):384-400

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100161086045.0x000001&indx=1&recIds=ETOCvdc_100161086045.0x000001

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Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

Authors: Nagao, Hirofumi, Cai, Weikang, Albrechtsen, Nicolai J. Wewer, Steger, Martin, Batista, Thiago M., Pan, Hui, Dreyfuss, Jonathan M., Mann, Matthias, Kahn, C. Ronald

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Apr . 118(17), 1-12.

Access URL: https://www.jstor.org/stable/27040200

Tissue differences in the exosomal/small extracellular vesicle proteome and their potential as indicators of altered tissue metabolism

Authors: Garcia-Martin, Ruben, Brandao, Bruna Brasil, Thomou, Thomas, Altindis, Emrah, Kahn, C. Ronald

Source: In Cell Reports 18 January 2022 38(3)

A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor

Authors: Zhang, Fa, Altindis, Emrah, Kahn, C. Ronald, DiMarchi, Richard D., Gelfanov, Vasily

Source: In Molecular Metabolism November 2021 53

Insulin action at a molecular level – 100 years of progress

Authors: White, Morris F., Kahn, C. Ronald

Source: In Molecular Metabolism October 2021 52

Insulin: A pacesetter for the shape of modern biomedical science and the Nobel Prize

Authors: Flier, Jeffrey S., Kahn, C. Ronald

Source: In Molecular Metabolism October 2021 52

miRNA-22 deletion limits white adipose expansion and activates brown fat to attenuate high-fat diet-induced fat mass accumulation

Authors: Lima, Vanessa M., Liu, Jianming, Brandão, Bruna B., Lino, Caroline A., Balbino Silva, Camila S., Ribeiro, Márcio A.C., Oliveira, Tiago E., Real, Caroline C., de Paula Faria, Daniele, Cederquist, Carly, Huang, Zhan-Peng, Hu, Xiaoyun, Barreto-Chaves, Maria Luiza, Ferreira, Julio C.B., Festuccia, William T., Mori, Marcelo A., Kahn, C. Ronald, Wang, Da-Zhi, Diniz, Gabriela P.

Source: In Metabolism April 2021 117

Apolipoprotein C3 and circulating mediators of preadipocyte proliferation in states of lipodystrophy

Authors: Brandao Bruna Brasil, Sakaguchi Masaji, Batista, Thiago Martins, Hu Jiang, Nie Song, Schepmoes Athena A, BonDurant Lucas, Moreau François, Qian Wei-Jun, Kulkarni N. Rohit, Kahn, C. Ronald

Source: Molecular Metabolism, Vol 64, Iss , Pp 101572- (2022)

Subject Terms: Adipogenesis, Inter-cellular crosstalk, Apolipoprotein, Metabolic syndrome, Circulating growth factor, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877822001417; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/485b206b95a246cd93c323de93b87a1b

Characterization of viral insulins reveals white adipose tissue-specific effects in mice

Authors: Chrudinová, Martina, Moreau, François, Noh, Hye Lim, Páníková, Terezie, Žáková, Lenka, Friedline, Randall H., Valenzuela, Francisco A., Kim, Jason K., Jiráček, Jiří, Kahn, C. Ronald, Altindis, Emrah

Source: In Molecular Metabolism February 2021 44

Hepatic SerpinA1 improves energy and glucose metabolism through regulation of preadipocyte proliferation and UCP1 expression.

Authors: Okagawa, Shota, Sakaguchi, Masaji, Okubo, Yuma, Takekuma, Yuri, Igata, Motoyuki, Kondo, Tatsuya, Takeda, Naoki, Araki, Kimi, Brandao, Bruna Brasil, Qian, Wei-Jun, Tseng, Yu-Hua, Kulkarni, Rohit N., Kubota, Naoto, Kahn, C. Ronald, Araki, Eiichi

Source: Nature Communications; 11/12/2024, Vol. 15 Issue 1, p1-19, 19p

Subject Terms: BROWN adipose tissue, ADIPOSE tissues, EPHRIN receptors, METABOLIC regulation, UNCOUPLING proteins, FAT cells

A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

Authors: Batista, Thiago M., Jayavelu, Ashok Kumar, Wewer Albrechtsen, Nicolai J., Iovino, Salvatore, Lebastchi, Jasmin, Pan, Hui, Dreyfuss, Jonathan M., Krook, Anna, Zierath, Juleen R., Mann, Matthias, Kahn, C. Ronald

Source: In Cell Metabolism 3 November 2020 32(5):844-859

Diabetes in ageing: pathways for developing the evidence base for clinical guidance

Authors: Munshi, Medha N ^*, Meneilly, Graydon S, Rodríguez-Mañas, Leocadio, Close, Kelly L, Conlin, Paul R, Cukierman-Yaffe, Tali, Forbes, Angus, Ganda, Om P, Kahn, C Ronald, Huang, Elbert, Laffel, Lori M, Lee, Christine G, Lee, Sei, Nathan, David M, Pandya, Naushira, Pratley, Richard, Gabbay, Robert, Sinclair, Alan J

Source: In The Lancet Diabetes & Endocrinology October 2020 8(10):855-867